Search clinical trials for: Drug Interactions

Total 260201 results

Pfizer

Completed

A STUDY TO EVALUATE THE EFFECT OF PF-06651600 ON PHARMACOKINETICS OF SINGLE DOSE SUMATRIPTAN IN HEALTHY PARTICIPANTS.

Healthy Volunteers

United States
University of Illinois at Chicago

Completed

Hop Botanical Dietary Supplements - Metabolism and Safety in Women

Food-Drug Interactions

United States
Centre Hospitalier Universitaire Vaudois

Completed

Drug-drug Interactions Between Antiretroviral Drugs and Cardiovascular Drugs in Elderly Patients

Cardiovascular Diseases | HIV Infections | Drug Interactions

Switzerland
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Completed

Clinical Trial to Evaluate Pharmacological Interactions Between γ-hydroxybutyrate (GHB) and Cobicistat (GHB_Cobi)

HIV | Pharmacokinetic Interactions

Spain
Rambam Health Care Campus
Weizmann Institute of Science

Unknown

Exploring Interactions Between Growth Hormone and the Microbiome

Growth Hormone Deficiency

Israel
Prof. Dr. med. Cornelius Bollheimer

Completed

The Pharmacist in the Acute Geriatric Inpatient Treatment Team (AGITATE)

Pharmacists in Geriatric Health Services | Conditions Unspecified

Germany
Aalborg University

Completed

A Mechanistic Evaluation of the Interactions Between Thermoceptive and Pruriceptive Sensory Processing

Itch | Histamine | Cowhage | Thermal Stimulation | Serotonine

Denmark
AstraZeneca
Parexel

Completed

A Study in Healthy Male Subjects to Understand How Savolitinib Behaves Inside the Body (Pharmacokinetics) When Administered Alone and in Combination With Famotidine

Solid Tumours

United States
University of Southern Denmark

Completed

Inter- and Intra-individual Variations in Metformin Pharmacokinetics - The Importance of Genes and Drug Interactions

Metformin | Organic Cation Transporter 1 | Codeine

Denmark
Sihuan Pharmaceutical Holdings Group Ltd.

Unknown

Pharmacokinetic Interactions of Quadruple Therapy With Anaprazole/Amoxicilin/Clarithromycin/Bismuth

Healthy Male Volunteers
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Completed

Influence of Fedratinib on the Pharmacokinetics of the Transporter Probe Substrates Digoxin, Rosuvastatin, and Metformin

Healthy Volunteers

United States
Fondation Ophtalmologique Adolphe de Rothschild

Withdrawn

Myofibroblastic Transformation Secondary to Epithelial-stromal Interactions in the Keratoconus (MYKE)

Keratoconus
Proteostasis Therapeutics, Inc.

Completed

Study Assessing the Safety, Tolerability, Pharmacokinetics, Food Effect, and Drug-Drug Interactions of PTI-801 in Healthy Volunteers, and Safety, Tolerability, and Pharmacokinetics of PTI-801 in Subjects With Cystic Fibrosis

Cystic Fibrosis | Healthy Volunteer

United States, Canada, Denmark, Germany, Sweden
Yale University
Boehringer Ingelheim

Completed

Pharmacokinetic Interactions Between Buprenorphine and Tipranavir/Ritonavir (BUTI)

HIV Infections

United States
Walter K. Kraft
Merck Sharp & Dohme LLC

Completed

Doravirine, Rifapentine and Isoniazid Interaction (DORIIS)

Latent Tuberculosis | Human Immunodeficiency Virus | Drug Interaction Potentiation | Rifamycins Causing Adverse Effects in Therapeutic Use

United States
ViiV Healthcare

Completed

Study to Evaluate the Pharmacokinetic (PK) Interactions Between GSK3640254 and Dolutegravir (DTG)

HIV Infections

United States
Assembly Biosciences

Completed

A Study to Assess CYP3A4 Modulator, Oral Contraceptive, and pH Modifier Drug Interactions for ABI-H2158 in Healthy Adults

Chronic Hepatitis B

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Gene-by-Stress Interactions in Intervention Studies Significance

Cardiovascular Diseases

United States
Mallinckrodt

Completed

Drug Interactions Between Morphine and Orally or IV Administered Acetaminophen

Pain

United States
Fundacion Clinic per a la Recerca Biomédica

Unknown

Clinical Trial to Evaluate the Efficacy, Pharmacokinetics (PK) Interactions and Safety of Dolutegravir Plus 2 Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in HIV-1-Infected Solid Organ Transplant Patients

HIV-1-infection | Solid Organ Transplant

Spain
CTI BioPharma
Covance

Completed

To Evaluate the Effect of Clarithromycin on the Systemic Exposure of Pacritinib in Healthy Subjects

Drug Interaction Study

United States
Nemours Children's Clinic
Merck Sharp & Dohme LLC

Completed

Transporter Mediated Uptake of Montelukast (TPORT)

Asthma

United States
Pfizer

Completed

Effect of Multiple Doses of Modafinil on the Pharmacokinetics of Single Dose Lorlatinib in Healthy Participants

Healthy Volunteers | Adult | Drug Interactions | Humans

Belgium
Bridge Biotherapeutics, Inc.
KCRN Research, LLC

Completed

Assess the Drug Interactions of BBT-877 and Midazolam, Itraconazole, and Esomeprazole in Healthy Adult Subjects

Healthy Participants

United States
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical...

Unknown

Identification of P-cresyl Sulfate Producer Phenotype by Oral Tyrosine Challenge Test: Interactions Among Diet, Gut Microbiota, and Host Genome

Healthy | Chronic Kidney Diseases

Taiwan
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Investigating the Interactions of AZD0530 With Alcohol in Social Drinkers

Alcohol Drinking

United States
IlDong Pharmaceutical Co Ltd

Unknown

To Evaluate the Pharmacokinetic/Pharmacodynamic Interactions and Safety Between ID1801 and ID1803 in Healthy Male Adults

Hypertension | Dyslipidemias
Indiana University
National Institute of General Medical Sciences (NIGMS)

Completed

Bupropion Stereoselective Disposition and CYP2D6-mediated Drug Interactions in Healthy Volunteers

Adverse Effect of Drug Therapy Metabolism Medications (Diagnosis)

United States
National Human Genome Research Institute (NHGRI)

Terminated

Genetic Analysis of Neural Tube and Orofacial Cleft Defects in the Irish Population

Hereditary Oral Clefts | Neural Tube Defects (NTDs) | Facial Cleft Defect

United States
Germans Trias i Pujol Hospital
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la... and other collaborators

Completed

Study to Evaluate the Influence of Nevirapine to Atazanavir in Steady State Equilibrium in HIV Patients

HIV Infections

Spain
Germans Trias i Pujol Hospital
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la... and other collaborators

Completed

Drug Interactions Between Echinacea Purpurea and Darunavir/Ritonavir

HIV Infections

Spain
Ain Shams University

Unknown

Evaluation of Drug Interactions of Saxagliptin With Sildenafil in Healthy Volunteers

Diabetes Mellitus, Type 2 | Drug Interaction | Erectile Dysfunction With Diabetes Mellitus
Pfizer

Completed

Evaluate Taste and Relative Bioavailability of Two Microsphere Formulations of Crizotinib in Healthy Participants

Healthy Volunteers

United States
Fundación FLS de Lucha Contra el Sida, las Enfermedades...
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau; Irs...

Completed

Drug Interactions Between Silimarine and Darunavir/Ritonavir

HIV

Spain
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Completed

Drug Interactions Between Echinacea Purpurea and Etravirine

HIV

Spain
Idorsia Pharmaceuticals Ltd.

Completed

A Clinical Study to Examine the Drug-drug Interactions Between ACT-541468 and Citalopram in Healthy Male and Female Subjects

Healthy

Germany
Paul Gougis

Unknown

PRevention of INteractions Between Phytotherapies and CancEr Treatments by a SmartphonE/Tablet Automated SurvEy (PRINCESSE)

Cancer

France
Beijing Continent Pharmaceutical Co, Ltd.

Completed

Pharmacokinetic Interactions Between Hydronidone and Entecavir Capsules in Healthy Chinese Subjects

Hydronidone

China
Genelex Corporation
Harding University

Completed

Pharmacogenetic Testing Among Home Health Patients

Drug Interaction Potentiation | Adverse Drug Events | Adverse Drug Reactions | Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant | Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant | Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 Enzyme... and other conditions

United States
Hanmi Pharmaceutical Company Limited

Completed

A Study to Evaluate the Pharmacokinetic and Pharmacodynamic Interactions Between HGP0904, HGP0608, and HCP1306 in Healthy Male Subjects.

Healthy

Korea, Republic of
Zagazig University

Completed

Risk Factors for Potential Drug -Drug Interactions: Study in Surgical Intensive Care Unit -Zagazig University Hospitals.

Drug Interaction

Egypt
H. Lee Moffitt Cancer Center and Research Institute
National Institutes of Health (NIH)

Completed

Drug /Cue Interactions In Alcohol-Tobacco Comorbidity

Nicotine Dependence

United States
University of Washington
Fred Hutchinson Cancer Center; National Institute of General Medical Sciences...

Completed

Sulforaphane as an Antagonist to Human PXR-mediated Drug-drug Interactions

Adverse Drug Interactions

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Phenotypic Drug Probes as Predictors of Drug-drug Interactions With Tacrolimus

Kidney Transplantation | Drug Interactions

Belgium
Galmed Pharmaceuticals Ltd
Hammersmith Medicines Research; Diamond Pharma Services Regulatory Affairs... and other collaborators

Completed

Study of Potential for Drug Interactions Mediated by CYP3A4 Inhibition With Aramchol in Healthy Volunteers

Healthy

United Kingdom
Pop Test Oncology LLC
Baylor College of Medicine; University of California, San Diego; Michael E. DeBakey... and other collaborators

Completed

Clinical Trial to Evaluate the Safety of PT150 (Formerly ORG34517) When it is Taken Concurrently With Alcohol

Alcohol Dependence | Alcohol Interaction

United States
Nanjing Sanhome Pharmaceutical, Co., Ltd.

Completed

A Drug-drug Interaction Study of SH229 Tablets and Daclatasvir Dihydrochloride Tablets in Healthy Subjects

Drug Interactions

China
George Mason University
National Institute on Drug Abuse (NIDA)

Completed

Parent-Adolescent Interactions and Adolescent Development (PAIT)

Substance Abuse

United States
University of Sao Paulo

Unknown

Effect of Anti-epileptic Drugs on Etonogestrel-releasing Implant Pharmacokinetics in Women With Epilepsy

Contraception | Drug Interactions

Brazil
National Taiwan University Hospital

Completed

Effect of Everolimus on the Pharmacokinetics of Tacrolimus in Renal Transplant Patients

Drug Interaction Potentiation

Taiwan

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