Search clinical trials for: Non alcoholic steatohepatitis

Total 53409 results

Madrigal Pharmaceuticals, Inc.

Active, not recruiting

A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and Fibrosis (MAESTRO-NASH)

NASH - Nonalcoholic Steatohepatitis

United States, Spain, Australia, United Kingdom, Canada, Israel, Belgium, Italy, France, Puerto Rico, Switzerland, Germany, Austria, Poland, Mexico, Hungary
Pfizer

Completed

A STUDY TO COMPARE THE PHARMACOKINETICS OF PF-06835919 IN PARTICIPANTS WITH AND WITHOUT HEPATIC IMPAIRMENT

Hepatic Impairment | Healthy Participants

Czechia, Slovakia, Belgium
Bristol-Myers Squibb

Terminated

Safety and Effectiveness of BMS-986263 in Adults With Compensated Cirrhosis (Liver Disease) From Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis (NASH)

United States, Germany, Taiwan, United Kingdom, Spain, Argentina, Brazil, France, Israel, Italy, Japan, Korea, Republic of, Belgium, Canada, Puerto Rico, Switzerland
89bio, Inc.

Active, not recruiting

Study Evaluating the Safety, Efficacy and Tolerability of BIO89-100 in Subjects With Biopsy-confirmed Nonalcoholic Steatohepatitis (NASH) (ENLIVEN)

NASH - Nonalcoholic Steatohepatitis

United States, Puerto Rico
AstraZeneca
Parexel

Completed

A Study to Assess Safety, Tolerability, PK and PD of AZD2693 in Non-alcoholic Steatohepatitis Patients

Non-alcoholic Steatohepatitis (NASH)

United States
Tanta University

Active, not recruiting

Comparative Study Between Obeticholic Acid Versus Vitamin E in Patients With Non-alcoholic Steatohepatitis

Non-alcoholic Steatohepatitis

Egypt
Zydus Therapeutics Inc.

Completed

Saroglitazar Magnesium in Patients With Nonalcoholic Fatty Liver Disease and/or Nonalcoholic Steatohepatitis (EVIDENCES IV)

Nonalcoholic Steatohepatitis | Non-Alcoholic Fatty Liver Disease

United States
Zydus Therapeutics Inc.

Completed

Saroglitazar Magnesium in the Treatment of Non-Alcoholic Steatohepatitis (EVIDENCES VI)

Non Alcoholic Steatohepatitis

United States
Johannes Gutenberg University Mainz
Goethe University

Completed

Role of a Wheat Containing Diet on Non-alcoholic Steatohepatitis (NASH-ATI)

Diabetes Mellitus, Type 2 | Hyperlipidemias | NASH - Nonalcoholic Steatohepatitis

Germany
University of California, San Francisco
University of Colorado, Denver; The Methodist Hospital Research Institute

Terminated

Mild Hypothermia and Acute Kidney Injury in Liver Transplantation (MHALT)

End Stage Liver Disease | Chronic Kidney Diseases | Hepatitis B | Hepatocellular Carcinoma | Cirrhosis | Acute Kidney Injury | NASH - Nonalcoholic Steatohepatitis | Liver Transplant; Complications | Alcoholic Cirrhosis | Hepatitis c

United States
Sagimet Biosciences Inc.

Completed

A Phase I Pharmacokinetic Study of TVB-2640 (Denifanstat) in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic Function

Cirrhosis | Hepatic Impairment | Non-alcoholic Steatohepatitis

United States, Hungary
Sagimet Biosciences Inc.

Completed

Study of TVB-2640 in Subjects With Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Fatty Liver Disease

United States, Canada, Puerto Rico, Poland
Novartis Pharmaceuticals

Terminated

Efficacy, Safety and Tolerability of the Combination of Tropifexor & Licogliflozin and Each Monotherapy, Compared With Placebo in Adult Patients With NASH and Liver Fibrosis. (ELIVATE)

Non Alcoholic Steatohepatitis (NASH)

United States, South Africa, Spain, Germany, Italy, Taiwan, Canada, Korea, Republic of, Singapore, Bulgaria, Estonia, Mexico, Japan, Denmark, United Kingdom, Colombia, Brazil, Belgium, Russian Federation, Puerto Rico, Chile, Argen... and more
University of Wisconsin, Madison
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); GE... and other collaborators

Active, not recruiting

Technical Validation of MR Biomarkers of Obesity-Associated NAFLD (NAFLD)

Non-Alcoholic Fatty Liver Disease | Non-alcoholic Steatohepatitis

United States
University of California, Davis
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Active, not recruiting

Non-alcoholic Fatty Liver Disease Parametric PET (FLiPP) Study (FLiPP)

Non-alcoholic Fatty Liver Disease (NAFLD) | Non-alcoholic Steatohepatitis (NASH)

United States
Lipocine Inc.

Completed

The Efficacy, Safety and Tolerability of Oral LPCN 1144 in Subjects With Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis (NASH)

United States
AstraZeneca
Parexel

Completed

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of AZD9550 Following Single Ascending Dose Administration to Healthy Participants

Non-alcoholic Steatohepatitis

United Kingdom
Novo Nordisk A/S

Completed

A Research Study Looking Into Blood and Urine Levels of the Medicine NNC0194-0499 in the Body and How Well it is Tolerated in Participants With Reduced Kidney Function and Normal Kidney Function

Non-alcoholic Steatohepatitis (NASH)

Germany
Cascade Pharmaceuticals, Inc
Laboratory Corporation of America

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of CS0159 in Subjects With NASH

Nonalcoholic Steatohepatitis (NASH)

United States
Redx Pharma Plc
Simbec Research

Completed

A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers

Liver Diseases | Fibrosis | Kidney Diseases | Inflammation | Idiopathic Pulmonary Fibrosis | Non-alcoholic Steatohepatitis

United Kingdom
Merck Sharp & Dohme LLC

Completed

A Study of Efinopegdutide (MK-6024) in Participants With Nonalcoholic Fatty Liver Disease (NAFLD) (MK-6024-001)

Nonalcoholic Fatty Liver Disease | Nonalcoholic Steatohepatitis

United States, Argentina, Australia, Canada, France, Israel, Italy, Korea, Republic of, Mexico, New Zealand, Poland, Russian Federation, Spain, Taiwan, Turkey, Ukraine
University of Pittsburgh
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Active, not recruiting

The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes (TRIABETES)

Obesity | Type 2 Diabetes Mellitus

United States
Galectin Therapeutics Inc.

Active, not recruiting

Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis (NAVIGATE)

Cirrhosis | NASH - Nonalcoholic Steatohepatitis | Prevention of Esophageal Varices

United States, France, Spain, Australia, Canada, Israel, Puerto Rico, Belgium, Argentina, Chile, Germany, Korea, Republic of, Mexico, Poland, United Kingdom
University of Pittsburgh

Completed

Integrated Approaches for Identifying Molecular Targets in Liver Disease (InLi)

Steatohepatitis, Nonalcoholic | Alcoholic Liver Disease | Non-Alcoholic Fatty Liver Disease | Steatohepatitis

United States
Natalie Torok

Active, not recruiting

Novel MRE Technique to Assess a Risk Factor for Liver Cancer

NASH - Nonalcoholic Steatohepatitis

United States
Stanford University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Active, not recruiting

Study of Oral Idebenone to Treat Non-Alcoholic Steatohepatitis

Non Alcoholic Steatohepatitis

United States
Intercept Pharmaceuticals

Completed

Study Evaluating the Efficacy and Safety of Obeticholic Acid in Subjects With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (REVERSE)

Nonalcoholic Steatohepatitis | Compensated Cirrhosis

United States, Spain, France, Australia, New Zealand, Puerto Rico, Germany, Canada, United Kingdom, Hungary, Poland, Ukraine
McGill University Health Centre/Research Institute...
Merck Sharp & Dohme LLC

Completed

Raltegravir-based Antiretroviral Versus Maintaining Any Other Antiretroviral Therapy in HIV Mono-infected Patients

Fatty Liver | HIV | Nonalcoholic Steatohepatitis

Canada
Intercept Pharmaceuticals

Terminated

Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment (REGENERATE)

Non Alcoholic Steatohepatitis (NASH)

United States, Finland, France, Spain, United Kingdom, Israel, Austria, Italy, Denmark, Germany, Belgium, Switzerland, Puerto Rico, Poland, Australia, Sweden, Serbia, New Zealand, Canada, Hungary, Portugal
Novo Nordisk A/S

Completed

Barriers to MASLD Management in Europe: Findings From a Multidisciplinary HCP-survey (BARRIERS-MASLD)

Non-alcoholic Steatohepatitis (MASH) | Non-alcoholic Fatty Liver Disease (MASLD)

India
Madrigal Pharmaceuticals, Inc.

Completed

Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses of MGL-3196 in Subjects With Varying Degrees of Hepatic Impairment and Healthy Matched Control Subjects

Hepatic Impairment | NASH - Nonalcoholic Steatohepatitis | Cirrhosis, Liver

United States
Terns, Inc.

Completed

DUET Study: A Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Orally Administered TERN-501 as Monotherapy and in Combination With TERN-101 in Noncirrhotic Adults With Presumed Non-Alcoholic Steatohepatitis

NASH - Nonalcoholic Steatohepatitis

United States
Aligos Therapeutics

Completed

A Study of ALG-055009 in Healthy Volunteers and Subjects With Hyperlipidemia

NASH - Nonalcoholic Steatohepatitis

France
ChemomAb Ltd.

Completed

The Study of Multiple Doses of CM-101 in Male and Female NAFLD (Nonalcoholic Fatty Liver Disease) and NAFLD/NASH (Nonalcoholic Steatohepatitis) Subjects

Nonalcoholic Fatty Liver Disease

Israel
ChemomAb Ltd.

Completed

Subcutaneous Doses of CM-101 as a Treatment for Medical Conditions Involving Inflammatory and Fibrotic Mechanisms in Healthy Male Subjects

Nonalcoholic Steatohepatitis (NASH) | Primary Sclerosing Cholangitis (PSC) | Systemic Sclerosis (SSc)

Israel
Northwell Health

Completed

Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy

Kidney Stones

United States
Madrigal Pharmaceuticals, Inc.

Completed

A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Non Alcoholic Fatty Liver Disease Patients (MAESTRO-NAFLD1)

Non-Alcoholic Fatty Liver Disease

United States, Puerto Rico
University of California, Davis

Completed

Evaluation of Multi-Organ Metabolism and Perfusion in NAFLD by Total Body Dynamic PET Scan on EXPLORER (EXPLORER)

Nonalcoholic Steatohepatitis (NASH) | Non-Alcoholic Fatty Liver Disease (NAFLD)

United States
Corcept Therapeutics

Active, not recruiting

A Sub Study of the Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant in Patients With Presumed Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis (NASH)

United States
University Hospital for Infectious Diseases, Croatia
Croatian Science Foundation

Completed

The Role of Immune Semaphorins in NAFLD (SepsisFAT)

Immune Response | Biomarkers | Liver Fibrosis | Non-Alcoholic Fatty Liver Disease | Non Alcoholic Steatohepatitis

Croatia
Poxel SA

Completed

Study of PXL065 in Patients With Nonalcoholic Steatohepatitis (NASH)

NASH - Nonalcoholic Steatohepatitis

United States
Perspectum
King's College Hospital NHS Trust; University of Coimbra; Liverpool University... and other collaborators

Completed

Non-invasive Rapid Assessment of NAFLD Using Magnetic Resonance Imaging With LiverMultiScan (RADIcAL1)

Metabolic Syndrome | NAFLD | NASH - Nonalcoholic Steatohepatitis

United Kingdom, Germany, Netherlands, Portugal
Indiana University
Sonic Incytes

Terminated

Quantitative Ultrasound With Liver Incytes for Evaluation of Non-Alcoholic Fatty Liver Disease

NAFLD | NASH - Nonalcoholic Steatohepatitis

United States
Novartis Pharmaceuticals

Terminated

Study of Various Treatments in Non-alcoholic Fatty Liver Disease (NAFLD) Patients Who Have Aspects of Non-alcoholic Steatohepatitis (NASH) (NEXSCOT)

Non-alcoholic Fatty Liver Disease | Nonalcoholic Steatohepatitis

United States, Germany, Argentina
RWTH Aachen University

Completed

Dietary Modulation of Intestinal Microbiota as Trigger of Liver Health: Role of Bile Acids - "A Diet for Liver Health" (ADLH)

NASH - Nonalcoholic Steatohepatitis

Sweden, Austria, Germany
Vanderbilt University

Enrolling by invitation

Abundance and Distribution of Lipids and Proteins in Nonalcoholic Fatty Liver Disease (NAFLD)

Nonalcoholic Fatty Liver Disease

United States
Sinew Pharma Inc.

Completed

Phase I Pharmacokinetic Study of HUYPS-1 in Healthy Volunteers

Nonalcoholic Steatohepatitis

Taiwan
University of Missouri-Columbia

Completed

The Liver Health Study for Patients With NAFLD

Obesity | Nonalcoholic Steatohepatitis | Nonalcoholic Fatty Liver

United States
Indiana University School of Medicine

Terminated

Vitamin E for NASH Treatment in HIV Infected Individuals

HIV Infections | NAFLD | NASH - Nonalcoholic Steatohepatitis

United States
Inventiva Pharma

Completed

Phase 2b Study in NASH to Assess IVA337 (NATIVE)

Non-Alcoholic Steatohepatitis (NASH)

United States, Spain, United Kingdom, France, Belgium, Austria, Switzerland, Australia, Germany, Slovenia, Bulgaria, Canada, Czechia, Italy, Mauritius, Poland

Search clinical trials for: Non alcoholic steatohepatitis

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