Search clinical trials for: Pleural diseases

Total 376490 results

Johns Hopkins University
Medical University of South Carolina; Vanderbilt University Medical Center; University... and other collaborators

Recruiting

Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System (NEWTON)

Pleural Effusion

United States, United Kingdom
National Cancer Institute (NCI)

Recruiting

Long Term Follow-up of Mesothelioma Patients and Their Family Members With Germline Mutations in BAP1 and Other Genes

Mesothelioma | Families

United States
Abramson Cancer Center at Penn Medicine

Recruiting

Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM)

Mesotheliomas Pleural

United States
Inhibrx, Inc.

Recruiting

Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

Sarcoma | Pancreatic Adenocarcinoma | Ewing Sarcoma | Gastric Adenocarcinoma | Chondrosarcoma | Solid Tumors | Malignant Pleural Mesothelioma | Colorectal Adenocarcinoma | GIST | SDH-deficient Solid Tumors

United States
University Hospital Olomouc
Thomayer University Hospital

Recruiting

Efficacy and Analgesic Use During the Therapy of Iatrogenic Pneumothorax Using Pleuralvent™ and Chest Tube (ASPIRATE)

Pneumothorax

Czechia
Rennes University Hospital

Recruiting

Outpatient Management of Primary Spontaneous Pneumothorax: Pigtail Catheter With Unidirectional Valve vs. Exsufflation, Randomized Prospective Study (PNEUM-AMBU)

Pneumothorax, Spontaneous

France
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Recruiting

Prospectively Collected Pleural Biopsies for Validation of Malignant Pleural Mesothelioma Prognostic Biomarkers

Mesothelioma

United States
Dr. Wiley Chung

Recruiting

VATS Decortication Versus IR Guided Chest Tube Insertion With Fibrinolytics for the Management of Empyema (DICE)

Empyema, Pleural

Canada
KU Leuven

Not yet recruiting

IP3R Modulation by Cancer Genes in Mesothelioma

Malignant Mesothelioma
VM Oncology, LLC

Recruiting

Selective TrkA Inhibitor VMD-928 to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

Sarcoma | Cervical Cancer | Breast Cancer | Adenoid Cystic Carcinoma | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Thymic Carcinoma | Lung Cancer | Mesothelioma | Bladder Cancer | Head and Neck Carcinoma | Uterine Cancer | Any Solid Tumors Progressed After a Prior Immunotherapy

United States, Puerto Rico
Istituto Scientifico Romagnolo per lo Studio e...

Recruiting

Pembrolizumab Plus Autologous Dendritic Cell Vaccine in Patients With PD-L1 Negative Advanced Mesothelioma Who Have Failed Prior Therapies (MESOVAX)

Progressive Disease | Mesothelioma, Malignant | Advanced Cancer | PD-L1 Negative

Italy
National Taiwan University Hospital

Recruiting

Treatment of Macrolide-resistant Mycoplasma Pneumoniae

Pneumonia, Mycoplasma

Taiwan
University Hospital, Toulouse

Recruiting

Automated Oxygen Administration in Patients With Hypoxemic Pneumonia and Pleuropneumonia (OPPAÎ)

Pneumonia | Pneumonia, Ventilator-Associated | Length of Stay

France
University Hospital, Akershus

Recruiting

Computed Tomography (CT) Guided Lung Biopsy With Plug

Computed Tomography, Biopsy, Pneumothorax, Chest Tube, Plug

Norway
Institut Bergonié
Bayer; Merck KGaA, Darmstadt, Germany

Recruiting

A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors (REGOMUNE)

Hepatocellular Carcinoma | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Soft-tissue Sarcoma | Urothelial Carcinoma | Thyroid Cancer | Gastro-enteropancreatic Neuroendocrine Tumor | Biliary Tract Cancer | HPV-Related Carcinoma | Solid Tumor, Adult | Mesotheliomas Pleural | GIST | Renal Carcinoma | Colorectal... and other conditions

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Indwelling Pleural Catheters With or Without Doxycycline in Treating Patients With Malignant Pleural Effusions

Pleural Neoplasm

United States
Postgraduate Institute of Medical Education and...

Recruiting

Minirigid Versus Conventional Rigid Thoracoscopy in Undiagnosed Pleural Effusions (MICRO)

Pleural Effusion

India
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Cutaneous Melanoma | Recurrent Malignant Female Reproductive System Neoplasm | Refractory Malignant Female Reproductive System Neoplasm | Recurrent Lip and Oral Cavity Carcinoma | Recurrent Malignant Endocrine... and other conditions

United States
Istituto Scientifico Romagnolo per lo Studio e...

Recruiting

Accelerated Hypofractionated Radiotherapy in the Treatment of Malignant Pleural Mesothelioma (MesoRT)

Malignant Pleural Mesothelioma

Italy
Checkpoint Therapeutics, Inc.
Novotech (Australia) Pty Limited

Recruiting

Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancers

Melanoma | Renal Cell Carcinoma | Head and Neck Cancer | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Non Hodgkin Lymphoma | Endometrial Cancer | Carcinoma, Small Cell | Urothelial Carcinoma | Classical Hodgkin Lymphoma | Merkel Cell Carcinoma | Cutaneous Squamous Cell Carcinoma | Malignant Mesothelioma, Advanced

Australia, New Zealand, Thailand, Ukraine, Spain, Russian Federation, France, Poland, South Africa
University of Calgary
Alberta Health services

Recruiting

The Management of Traumatic Hemothoraces (HemoTxRCT)

Hemothorax | Thoracic Injuries

Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Brentuximab Vedotin in Treating Patients With CD30+ Malignant Mesothelioma That Cannot Be Removed by Surgery

Malignant Mesothelioma | CD30-Positive Neoplastic Cells Present

United States
University of Oklahoma

Recruiting

Use of Endobronchial Ultrasound Scope (EBUS) Transducer to Identify Pneumothorax-A Feasibility Study

Pneumothorax

United States
Odense University Hospital
Danish Medical Association; Danmarks Lungeforening

Recruiting

Study Designed to Optimize the Treatment of Primary Pneumothorax (TOPP)

Primary Spontaneous Pneumothorax | Pleural Disease

Denmark
Rigshospitalet, Denmark

Recruiting

uPAR-PET for Prognostication in Patients With Non-small Cell Lung Cancer, Malignant Pleural Mesothelioma and Large Cell Neuroendocrine Carcinoma of the Lung

Non-small Cell Lung Cancer | Malignant Pleural Mesothelioma | Large Cell Neuroendocrine Carcinoma of the Lung

Denmark
University of Chicago

Recruiting

A Pilot Window-Of-Opportunity Study of the Anti-PD-1 Antibody Pembrolizumab in Patients With Resectable Malignant Pleural Mesothelioma

Pleural Mesothelioma

United States
Mayo Clinic

Recruiting

Staging Procedures to Diagnose Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
Mayo Clinic

Recruiting

Chemotherapy Followed by Surgery and Neoadjuvant Hemothoracic Intensity Modified Radiation Therapy (IMRT) for Patients With Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
Mayo Clinic

Recruiting

Surgery for Mesothelioma After Radiation Therapy "SMART" for Resectable Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
Abramson Cancer Center at Penn Medicine

Recruiting

Phase II Trial of Radical Pleurectomy With or Without Intraoperative PDT for Malignant Pleural Mesothelioma (MPM-PDT)

Epitheliod Malignant Pleural Mesothelioma

United States
Eastern Regional Medical Center

Recruiting

Combination Tissue Plasminogen Activator (Tpa) and Dornase Alfa (Dnase) Administration Through Intrapleural Catheters for the Treatment of Loculated or Non-Draining Malignant Pleural Effusions

Loculated or Non-draining Malignant Pleural Effusions

United States
National Cancer Institute (NCI)

Recruiting

Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma

Stomach Neoplasms | Pancreatic Neoplasms | Thymoma | Mesothelioma | Biliary Tract Neoplasms

United States
Medical University of Vienna

Recruiting

Establishment of a Tumor Bank for Tissue Samples

Endocrine Gland Neoplasms | Breast Neoplasms | Lung Neoplasms | Colorectal Neoplasms | Ovarian Neoplasms | Neoplasms of the Female Genitalia

Austria, Germany, Belgium
Centre hospitalier de l'Université de Montréal...

Recruiting

Cervical Video Assisted Thoracoscopic Surgery (C-VATS) (CT0030)

Lung Cancer

Canada
Lung Clinic Hemer

Recruiting

Breath Analysis by Ion Mobility Spectrometry

Lung Diseases

Germany
National Cancer Institute (NCI)

Recruiting

Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

Malignant Pleural Mesotheliomas NOS | Esophageal Cancers NOS | Lung Cancer NOS | Thoracic Cancers | Cancers of Non Thoracic Origin With Metastases to the Lungs or Pleura

United States
National Cancer Institute (NCI)

Recruiting

Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer

Kidney Cancer | Kidney Neoplasms | Pneumothorax | FLCN Protein, Human

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Study of the Disease Process of Lymphangioleiomyomatosis

Pneumothorax | Tuberous Sclerosis | Lung Disease | Lymphangioleiomyomatosis

United States
Ikena Oncology

Active, not recruiting

Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects With Advanced Solid Tumors

Solid Tumor | Solid Tumors, Adult | Malignant Pleural Mesothelioma (MPM) | Epithelioid Hemangioendothelioma (EHE) | NF2 Deficient Mesothelioma | Other NF2 Deficient Solid Tumors and Solid Tumors With YAP1/TAZ Fusion Genes | NF2 Deficiency | YAP1 or TAZ Gene Fusions

United States, United Kingdom
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Using a Targeted Cancer Vaccine (Galinpepimut-S) With Immunotherapy (Nivolumab) in Mesothelioma

Mesothelioma | Wilms Tumor | Pleural Mesothelioma

United States
Bayer

Active, not recruiting

Impact of Multiple Doses of BAY63-2521 on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Patients With Interstitial Lung Disease (ILD) Associated Pulmonary Hypertension (PH)

Hypertension, Pulmonary

Germany
National Cancer Institute (NCI)

Completed

Collection of Malignant Ascites, Pleural Fluid, and Blood From People With Solid Tumors

Cancer | Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesothelioma

Epithelioid Mesothelioma | Pleural Malignant Mesothelioma | Sarcomatoid Mesothelioma | Recurrent Malignant Mesothelioma

United States
Daryoush Hamidi Alamdari, PhD

Completed

Persistent Pleural Effusion Treatment Following Cardiothoracic Surgery by Platelet-Fibrin Glue

Pleural Effusion

Iran, Islamic Republic of
National Cancer Institute (NCI)

Active, not recruiting

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

Biphasic Mesothelioma | Epithelioid Mesothelioma | Stage III Pleural Malignant Mesothelioma AJCC v7 | Stage I Pleural Malignant Mesothelioma AJCC v7 | Stage IA Pleural Malignant Mesothelioma AJCC v7 | Stage IB Pleural Malignant Mesothelioma AJCC v7 | Stage II Pleural Malignant Mesothelioma AJCC...

United States
Roswell Park Cancer Institute

Suspended

Photodynamic Therapy to Amplify the Response to Immunotherapy in Patients With Non-small Cell Lung Cancer With Pleural Disease

Lung Non-Small Cell Carcinoma | Pleural Disorder

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Triple-Negative Breast Carcinoma and other conditions

United States, Canada
M.D. Anderson Cancer Center

Suspended

A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers

Small Cell Lung Cancer | Hodgkin's Lymphoma | Cervical Carcinoma | Peritoneal Mesothelioma | Pleural Mesothelioma | Neuroendocrine Carcinomas | Microsatellite High Cancers | Extrapulmonary High Grade

United States
Institut für Klinische Krebsforschung IKF GmbH...
Bristol-Myers Squibb

Active, not recruiting

Nivolumab With Chemotherapy in Pleural Mesothelioma After Surgery

Pleural Mesothelioma Malignant

Germany
Memorial Sloan Kettering Cancer Center
M.D. Anderson Cancer Center; Mayo Clinic; Brigham and Women's Hospital; Princess...

Active, not recruiting

Pleurectomy/Decortication (Neo) Adjuvant Chemotherapy and Intensity Modulated Radiation Therapy to the Pleura in Patients With Locally Advanced Malignant Pleural Mesothelioma

Mesothelioma

United States

Search clinical trials for: Pleural diseases

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