Search clinical trials for: Suboptimal molecular response

Total 107960 results

Boston Children's Hospital

Recruiting

Biomarkers of ADHD Treatment Response (BAT)

ADHD

United States
University of Kansas Medical Center

Recruiting

Neoadjuvant TIL- and Response-Adapted Chemoimmunotherapy for TNBC (NeoTRACT)

Breast Cancer | Triple Negative Breast Cancer

United States
University Hospital Dubrava

Recruiting

Evaluation of Intraoperative Dexmedetomidine Use in Patients Undergoing Surgical Aortic Valve Replacement

Aortic Valve Stenosis | Systemic Inflammatory Response

Croatia
Second Affiliated Hospital, School of Medicine,...

Recruiting

Clinical Efficacy of Indomethacin in Early Treatment of Acute Pancreatitis

Systemic Inflammatory Response Syndrome | Acute Pancreatitis

China
AstraZeneca
SWOG Clinical Trials Partnerships; Daiichi Sankyo

Recruiting

A Study of Dato-DXd With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Without Pathological Complete Response Following Neoadjuvant Therapy (TROPION-Breast03)

Breast Cancer

United States, China, Denmark, United Kingdom, Korea, Republic of, Canada, Germany, Italy, Belgium, Spain, Japan, France, Taiwan, Greece, Brazil, Sweden, Puerto Rico
Abraham Nunes
Nova Scotia Health Authority

Recruiting

Predictors of Intravenous Ketamine Response in TRD

Bipolar Disorder | Major Depressive Disorder | Treatment Resistant Depression

Canada
Qilu Hospital of Shandong University

Recruiting

The Clinical Efficacy of Immunomodulators in RA Patients

Arthritis, Rheumatoid

China
Rigshospitalet, Denmark
Lundbeck Foundation; Mental Health Centre Copenhagen; Center for Integrated Molecular...

Recruiting

Precision Medicine in the Depression Treatment (BDD)

Cognitive Dysfunction | Depressive Disorder, Major | Cognitive Behavioral Therapy | Treatment Outcome | Antidepressive Agents

Denmark
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation (JANUS)

Stage III Rectal Cancer AJCC v8 | Stage II Rectal Cancer AJCC v8 | Locally Advanced Rectal Carcinoma

United States, Puerto Rico
University Hospital, Bordeaux

Recruiting

CML Pediatric ITK Response According to Molecular Identification at Diagnosis (CML Piramid)

Chronic Myeloid Leukemia

France
Innovaderm Research Inc.

Recruiting

Effects of Abrocitinib in Subjects With Atopic Dermatitis With an Unsatisfactory Response After Treatment With Dupilumab

Atopic Dermatitis

Canada, United States
Guangdong Provincial People's Hospital

Recruiting

Patient-reported Outcomes in Preoperative Immunochemotherapy/Radiotherapy-treated Esophageal Cancer Patients (PICCRT)

Esophageal Squamous Cell Carcinoma | Immunotherapy | Patient-reported Outcomes

China
Yongpeng Wang

Recruiting

A Study of Fluzoparib Combined With QL1101 Maintenance Treatment in Patients With Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy

Ovarian Cancer

China
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Envafolimab, Lenvatinib Combined With TACE in the Treatment of Unresectable Locally Advanced Hepatocellular Carcinoma

Objective Response Rate (ORR)
Monash Medical Centre

Recruiting

Vocal Cord Responses During Hyperventilation in Normal Individuals and in Mild and Severe Asthmatics.

Asthma | Hyperventilation | Larynx

Australia
VA Office of Research and Development
VA Palo Alto Health Care System; VA Puget Sound Health Care System; Michael E... and other collaborators

Not yet recruiting

A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer

Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Gastroesophageal Junction Carcinoma

United States
Renmin Hospital of Wuhan University

Recruiting

Short-course Radiotherapy Combined With Neoadjuvant Chemotherapy and PD-1 Inhibitor in the Treatment of Locally Advanced Gastric Adenocarcinoma

Disorder in Complete Remission in Response to Treatment

China
GlaxoSmithKline

Recruiting

A Study on the Safety and Immune Response of AS37 Together With Hepatitis B Antigen in Adults Aged 18-45 Years

Hepatitis B

Germany, United Kingdom, Belgium
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

An Imaging Agent (Fluorodopa F 18) With Positron Emission Tomography/Magnetic Resonance Imaging for Assessing Treatment Response in Patients With High-Grade Soft Tissue Sarcomas

Soft Tissue Sarcoma | Recurrent Soft Tissue Sarcoma | Resectable Soft Tissue Sarcoma

United States
Ain Shams University

Not yet recruiting

Assessment of Rituximab Therapeutic Response Versus Conventional Treatment

Pharmacological Action
Hospital Garcia de Orta
Instituto de Medicina Molecular João Lobo Antunes

Recruiting

Diastolic Dysfunction in Septic Shock and Cardiomyopathy Genetic Variants (SepticHeartG)

Septic Shock | Cardiomyopathies | Diastolic Dysfunction

Portugal
St. Jude Children's Research Hospital
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

Solid Organ Transplant | Respiratory Viral Infection | Hematopoietic Cell Transplant

United States
Indonesia University

Recruiting

The Role of Simvastatin in The Epithelial-Mesenchymal Transition Process of Breast Cancer

Triple Negative Breast Cancer | Chemotherapy Effect | Simvastatin Adverse Reaction

Indonesia
Axsome Therapeutics, Inc.

Recruiting

Open-Label Study of AXS-07 for the Acute Treatment of Migraine in Adults With a Prior Inadequate Response to an Oral CGRP Inhibitor (EMERGE)

Migraine

United States
Mario Luca Morieri

Recruiting

Genetic-Dependent Cardiovascular Response to PPAR-Alpha Agonist Fenofibrate (MAGNETIC)

Cardiovascular Diseases | Type 2 Diabetes | Pharmacogenomic Drug Interaction

Italy
Mclean Hospital

Recruiting

SMART Trial to Predict Anhedonia Response to Antidepressant Treatment

Major Depressive Disorder

United States
RenJi Hospital
Peking University First Hospital; Fudan University; Shanghai Zhongshan Hospital; First Affiliated Hospital, Sun Yat-Sen University and other collaborators

Recruiting

Molecular Markers in Predicting Response to Treatment in FH-deficient RCC Patients

Biomarkers | FH-Deficient RCC | Systemic Treatments

China
Hospices Civils de Lyon

Recruiting

Predictive Clinical Features for Response to Adjuvant Immunotherapy in Stage II,III and IV Resected Melanoma (Mel-ImmAdj)

Melanoma

France
Taipei Veterans General Hospital, Taiwan

Not yet recruiting

The Application and Validation of Triple Drug Response Surface Models on Density Spectral Array in Clinical Anesthesia

Anesthesia | Drug Interaction | Anesthesia; Functional

Taiwan
National Cancer Centre, Singapore
National University Hospital, Singapore; Singapore General Hospital; Tan Tock... and other collaborators

Recruiting

Deep, Multi-omics Phenotyping to Predict Response, Resistance and Recurrence to Adjuvant Atezolizumab Plus Bevacizumab in Resected Hepatocellular Carcinoma (EMPHASIS)

Hepatocellular Carcinoma

Singapore
University of California, San Diego

Recruiting

Effects of Cannabidiol and Tetrahydrocannabinol on Microbiome and Neuroinflammation in HIV (CAMI)

HIV | Cannabis | Microbiome | THC | Neuroinflammatory Response | Neuroinflammatory Disease

United States
Erasmus Medical Center

Recruiting

Biomarker Identification of Radionuclide Therapy-induced Radiation Responses (Radio-Marker)

Neuroendocrine Tumors

Netherlands
Peking University Cancer Hospital & Institute

Recruiting

Camrelizumab Plus Apatinib and Temozolomide as Neoadjuvant in High Risk Acral Melanoma

Melanoma | Temozolomide | Apatinib | Camrelizumab | Acral Melanoma | Neoadjuvant | Pathological Response

China
Ege University

Recruiting

Reduced Dose Thrombolytic in Intermediate/High Risk Pulmonary Thromboembolism

Pulmonary Embolism

Turkey
Henan Provincial People's Hospital

Not yet recruiting

Study on Gene Evolution in Glioma Under Stress Therapy

Genetic Change

China
Stephen Shiao
Merck Sharp & Dohme LLC; Incyte Corporation

Recruiting

Reinvigorating TNBC Response to Immunotherapy With Combination Myeloid Inhibition and Radiation

Breast Cancer | TNBC - Triple-Negative Breast Cancer

United States
The Children's Hospital of Zhejiang University...
First Affiliated Hospital, Sun Yat-Sen University; Tongji Hospital; Qilu Hospital... and other collaborators

Recruiting

Cytokine Guided Risk Stratification and Treatment in Pediatric Hemophagocytic Lymphohistiocytosis

Cytokine Storm | Hemophagocytic Lymphohistiocytoses

China
Zhenzhen Liu

Recruiting

Clinical Study of Camrelizumab Combined With TCb Versus TCb in Neoadjuvant Treatment of Triple-negative Breast Cancer

Breast Cancer | Triple Negative Breast Cancer | Camrelizumab

China
Beijing Tiantan Hospital
Beijing GeneX Health Technology Co., Ltd

Recruiting

PTCs-based Precision Treatment Strategy on Recurrent High-grade Gliomas

Recurrent High Grade Glioma

China
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Oral Ozanimod in Pediatric Participants With Moderately to Severely Active Crohn's Disease With an Inadequate Response to Conventional Therapy

Crohn Disease

United States, Belgium, Hungary, France, Canada, Spain, Australia, Germany, Poland, United Kingdom
Jonathan Sevransky
Regeneron Pharmaceuticals

Recruiting

Alirocumab in Patients With Sepsis (PALMS)

Sepsis

United States
Assiut University

Not yet recruiting

Comparing The Effect of Tadalafil 5 mg/Day to Sildenafil 25 mg/Day on Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios in Erectile Dysfunction Patients; and Comparison of Clinical Response

Erectile Dysfunction and Neutrophil Lymphocyte Ratio

Egypt
Unity Health Toronto
Centre for Addiction and Mental Health; Toronto Metropolitan University

Recruiting

Auditory MMN EEG in TRD in Response to Ketamine

Treatment-resistant Depression (TRD)

Canada
Gitte Moos Knudsen

Recruiting

Precision Medicine in the Treatment of Epilepsy (BDE)

Epilepsy

Denmark
University of Victoria

Recruiting

Role of Desloratadine in Reducing Inflammation From Occupational Heat Strain

Inflammatory Response | Heat Stress, Exertional | Firefighter Personal Protective Equipment

Canada
Tanta University

Not yet recruiting

Quadratus Lumborum Versus Transversus Abdominis Plane Block Versus Caudal Block for Postoperative Analgesia After Pediatric Inguinal Hernia : Double-Blinded Randomized Trial

Postoperative Pain | Inguinal Hernia | Caudal Block | Quadratus Lumborum Block | Transversus Abdominis Plane Block
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo; Coordenação de Aperfeiçoamento...

Not yet recruiting

Metabolic and Molecular Responses Under the Effect of Taurine Supplementation With and Without Multicomponent Training

Sarcopenic Obesity
University Medical Centre Ljubljana

Recruiting

Cytomegalovirus Prophylaxis With Letermovir in Heart Transplant Recipients (CYPHER-TXPilot)

CMV Viremia

Slovenia
Basilea Pharmaceutica

Not yet recruiting

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis

Candidemia | Candidiasis, Invasive
Melanoma Institute Australia
Bristol-Myers Squibb

Recruiting

A Phase 2 Clinical Trial of Neoadjuvant Relatlimab and Nivolumab in High Risk, Clinical Stage II Cutaneous Melanoma (Neo ReNi II)

Stage II Melanoma

Australia

Search clinical trials for: Suboptimal molecular response

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