Search clinical trials for: graf versus host disease

Total 391081 results

Singapore National Eye Centre
Singapore General Hospital

Completed

Ocular Surface Disease in Chronic Graft-Versus-Host Disease (GVHD) Patients

Dry Eye | GVHD

Singapore
Dana-Farber Cancer Institute
Roche-Genentech

Active, not recruiting

Obinutuzumab in cGVHD After Allogeneic Peripheral Blood Stem Cell Transplantation

Graft vs. Host Disease

United States
Polish Lymphoma Research Group
AstraZeneca

Active, not recruiting

Acalabrutinib in CLL and MCL Patients Subjected to Allogeneic Hematopoietic Stem Cell Transplantation (alloSCT) (ACALLO)

Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Adverse Event | Chronic Graft-versus-host-disease | Response Rate

Poland
Dimitrios Tzachanis, MD PhD
Bristol-Myers Squibb

Active, not recruiting

Comparing Cyclophosphamide and Abatacept With Standard of Care Treatment Following Stem Cell Transplantation

Hematologic Neoplasms | GVHD

United States
Memorial Sloan Kettering Cancer Center
Incyte Corporation; Hackensack Meridian Health

Completed

Study of the Safety and Efficacy of Ruxolitinib Cream for Non-Sclerotic Chronic Cutaneous Graft-Versus-Host Disease

Non-sclerotic Cutaneous Chronic Graft-versus-host Disease

United States
Genentech, Inc.

Completed

Study to Evaluate the Safety and Pharmacokinetics of Efmarodocokin Alfa in Combination With Standard of Care in Participants Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Acute Graft-versus-host Disease

United States
Incyte Corporation

Active, not recruiting

A Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Itacitinib

Chronic Graft Versus Host Disease | Myelofibrosis | Postlung Transplant (Bronchiolitis Obliterans)

United States, Spain, Italy, Germany, Belgium, Austria, Israel, Canada, Greece
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Extracorporeal Photopheresis and Low Dose Aldesleukin in Treating Patients With Steroid Refractory Chronic Graft-Versus-Host Disease

Chronic Graft Versus Host Disease

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801) (1703/1801)

Lymphoma | Acute Leukemia | Myelodysplasia | Chronic Myelogenous Leukemia (CML)

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease | Precancerous/Nonmalignant Condition
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Leflunomide in Treating Patients With Steroid Dependent Chronic Graft Versus Host Disease

Chronic Graft Versus Host Disease | Steroid Refractory Graft Versus Host Disease

United States
Guenther Koehne

Suspended

CD34+ Enriched Transplants to Treat Myelodysplastic Syndrome

Myelodysplastic Syndromes | Graft Vs Host Disease | Graft-versus-host-disease

United States
Janssen Korea, Ltd., Korea

Terminated

A Study to Investigate the Comparative Effectiveness of Ibrutinib in Steroid Dependent/Refractory cGVHD Participants

Chronic Graft vs Host Disease

Korea, Republic of
Amgen

Completed

Study of Efavaleukin Alfa in Healthy Chinese, Japanese, and Caucasian Participants

Inflammatory Diseases

United Kingdom
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center; Washington... and other collaborators

Active, not recruiting

Improving Outcomes Assessment in Chronic GVHD

Chronic Graft Versus Host Disease

United States
Fundación Pública Andaluza para la gestión de la...

Active, not recruiting

Ixazomib in the Prophylaxis of Chronic Graft-versus-host Disease.

Multiple Myeloma | Hematopoietic Stem Cell Transplantation

Spain
Incyte Corporation

Available

Expanded Access Program for Axatilimab in Chronic Graft Versus Host Disease (GVHD)

Chronic Graft Vs. Host Disease
Fundación Pública Andaluza para la gestión de la...
Instituto de Salud Carlos III

Active, not recruiting

Metabolome and Microbiome Impact on Acute GVHD in Recipients of Hematopoietic Transplant (AlloBolome)

Graft-versus-host Disease

Spain
Washington University School of Medicine
GlaxoSmithKline; American Cancer Society, Inc.

Completed

Belimumab for Prevention of Chronic Graft-versus-Host Disease Following Allogeneic Hematopoietic Cell Transplantation

Graft Vs Host Disease | Graft-versus-host-disease

United States
CytoDyn, Inc.
Amarex Clinical Research

Terminated

A Study of Acute Graft-Versus-Host Disease (GVHD) in Patients Undergoing Allogeneic Stem-Cell Transplantation (GVHD)

Graft Vs Host Disease

United States
NYU Langone Health

Completed

High-Dose Post-Transplant Cyclophosphamide and Bortezomib (CyBor) for the Prevention of Graft-versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

GVHD

United States
Massachusetts General Hospital
American Cancer Society, Inc.

Completed

FMT In High-Risk Acute GVHD After ALLO HCT

Hematopoietic Cell Transplantation | Acute Graft-Versus-Host Disease (Gvhd) Grade | Fecal Microbiota Transplant

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Tocilizumab for the Prevention of Graft Versus Host Disease After Cord Blood Transplantation

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Leukemia | Hodgkin Lymphoma | Myelodysplastic-Myeloproliferative Diseases | Acute Lymphoblastic Leukemia | Non Hodgkin Lymphoma | Acute Leukemia | Myeloproliferative Disorder

United States
Assistance Publique - Hôpitaux de Paris
GlaxoSmithKline

Terminated

Efficacy of Fluticasone Propionate Associated With Salmeterol Using Inhalation Chamber Versus Placebo to Improve the Respiratory Function in Children Over Six Years of Age Who Underwent Allogeneic Hematopoietic Stem Cell Transplantation With a Decline of FEV1 ≥10% From Pre Transplantation (RESPPEDOBS)

Bronchiolitis Obliterans | Respiratory Disease | Stem Cell Transplant Complications

France
Wang wanxia

Enrolling by invitation

A Study of Ropivacaine Complex Methylene Blue Fascia Iliaca Compartment Block on Analgesia in Patients Undergoing Hip Arthroplasty

Femoral Neck Disease

China
NYU Langone Health

Active, not recruiting

Cyclophosphamide, Abatacept, and Tacrolimus for GvHD Prevention

Graft-versus-host Disease

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

A Phase II Study of Allo-HCT for B-Cell NHL Using Zevalin, Fludarabine and Melphalan

Lymphoma | Leukemia | Graft Versus Host Disease

United States
Novartis Pharmaceuticals

Available

Managed Access Programs for INC424, Ruxolitinib

Primary Myelofibrosis (PMF) | Polycythemia Vera (PV) | Post Polycythemia Myelofibrosis (PPV MF) | Thrombocythemia Myelofibrosis (PET-MF) | Severe/Very Severe COVID-19 Illness | Steroid Refractory Acute Graft Versus Host Disease (SR aGVHD) | Steroid Refractory Chronic Graft Versus Host Disease...
Ruijin Hospital

Completed

Endocytoscopy of Upper Gastrointestinal Tract in Acute Graft-versus-host Disease: a Pilot Study

Endocytoscopy

China
CSL Behring
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Active, not recruiting

Treatment of GVHD in Hematopoietic Stem Cell Transplant (HSCT) Recipients Using AAT Plus Corticosteroids (CS) Compared With Corticosteroids Alone (BMT CTN 1705)

Graft Versus Host Disease (GVHD)

United States
Dana-Farber Cancer Institute
Prometheus Laboratories

Active, not recruiting

A Phase II Trial of Low-Dose Interleukin-2 (IL-2) Added to Extra-Corporeal Photopheresis for Steroid-Refractory cGVHD

Chronic Graft-versus-host-disease

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Prometheus Laboratories

Active, not recruiting

Daily IL-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease

Chronic Graft-versus-host Disease

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Prometheus Laboratories; Miltenyi Biomedicine...

Active, not recruiting

Trial of Regulatory T-cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease

Chronic Graft Versus Host Disease | Chronic GVHD | Complications of Organ Transplant Stem Cells

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Suspended

Electron Beam Radiotherapy for the Treatment of Refractory Sclerodermatous Chronic Graft Versus Host Disease

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm | Refractory Sclerodermatous Graft Versus Host Disease

United States
Genentech, Inc.

Terminated

A Study to Assess the Safety and Pharmacokinetics of GDC-8264 in Combination With Standard of Care in Participants With Acute Graft-Versus-Host Disease (aGVHD)

Acute Graft-versus-host Disease

United States, Canada
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb

Completed

CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease

GVHD | Graft-versus-host-disease | GVHD, Acute

United States
Incyte Corporation

Terminated

GRAVITAS-309: Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

Chronic Graft-versus-host Disease

United States, Spain, France, Canada, Israel, United Kingdom, Germany, Italy, Denmark, Sweden, Finland, Belgium, Poland, Greece, Austria, Switzerland
Oncoimmune, Inc., a subsidiary of Merck & Co.,...
National Cancer Institute (NCI); University of Michigan Rogel Cancer Center; Ohio... and other collaborators

Completed

Phase II Trial of Efprezimod Alfa (CD24Fc, MK-7110) for the Prevention of Acute Graft-Versus-Host Disease (GVHD) Following Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-002)

Leukemia | Hematopoietic Stem Cell Transplantation | Graft Versus Host Disease

United States
University of Utah
Incyte Corporation

Terminated

Itacitinib (INCB039110) and Extracorporeal Photopheresis (ECP) for First-Line Treatment in Chronic GVHD (FLIGHT)

Chronic Graft-versus-host-disease

United States
Assistance Publique - Hôpitaux de Paris

Active, not recruiting

To Compare the Efficacy of the Addition of Methotrexate (MTX) to Current Standard Acute Graft-versus-host Disease (GVHD) First-line Treatment With Corticosteroids (MTX-aGVHD)

Stem Cell Transplant Complications | GVHD, Acute | GVH - Graft Versus Host Reaction | Allogeneic Disease

France
Beth Israel Deaconess Medical Center
Bristol-Myers Squibb; Dana-Farber Cancer Institute

Completed

Abatacept to Treat Steroid Refractory Chronic Graft Versus Host Disease (cGVHD)

Chronic Graft Versus Host Disease

United States
BioNova Pharmaceuticals (Shanghai) LTD.

Completed

Efficacy and Safety of BN101 in Subjects With Chronic Graft Versus Host Disease (cGVHD)

GVHD, Chronic

China
Children's Hospital Medical Center, Cincinnati

Completed

Study of Ruxolitinib for Acute and Chronic Graft Versus Host Disease

Solid Organ Transplant | Acute-graft-versus-host Disease | Chronic Graft-versus-host-disease

United States
VectivBio AG

Active, not recruiting

Proof-of-concept Trial of Apraglutide in GVHD

GVHD

United States, Spain, Germany, Portugal
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplant

Follicular Lymphoma | Diffuse Large B-Cell Lymphoma | Hodgkin Lymphoma | Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | Myeloproliferative... and other conditions

United States
Cytopeutics Sdn. Bhd.
Universiti Tunku Abdul Rahman

Active, not recruiting

UCMSCs as Front-line Approach of Treatment for Patients With aGVHD (GVHD Cyto-MSC)

Acute-graft-versus-host Disease

Malaysia
Kadmon, a Sanofi Company

Terminated

Efficacy and Safety of KD025 in Subjects With cGVHD After At Least 2 Prior Lines of Systemic Therapy

Chronic Graft-versus-host-disease

United States
University of California, San Francisco

Completed

Dexamethasone Solution and Dexamethasone in Mucolox™

Oral Lichen Planus | Pemphigus Vulgaris | Mucous Membrane Pemphigoid | Chronic Graft-versus-host-disease

United States
University Health Network, Toronto

Active, not recruiting

A Randomized Phase II Study to Compare the Potential Long-Lasting Positive Effect of Decidual Stromal Cells to the Best Available Treatment in Graft Versus Host Disease

Graft Vs Host Disease

Canada
Jiangsu HengRui Medicine Co., Ltd.

Completed

To Assess SHR0302 Oral Solutions and Tablets in Healthy Subjects Clinical Studies of Relative Bioavailability

Graft-versus-host Disease

China

Search clinical trials for: graf versus host disease

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