Search clinical trials for: high dose dual therapy

Total 85701 results

Sun Yat-sen University

Enrolling by invitation

Chemotherapy Combined With High-dose Radiotherapy for Low Rectal Cancer Using MR Guided Linear Accelerator

Rectal Cancer

China
Sumitomo Pharma America, Inc.

Completed

A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy

Glioblastoma

United States, Korea, Republic of, Taiwan, Canada, Japan
Abbott Medical Devices
Bristol-Myers Squibb; Eli Lilly and Company; Daiichi Sankyo, Inc.; Baim Institute...

Completed

XIENCE V® USA Dual Antiplatelet Therapy (DAPT) Cohort (XVU-AV DAPT)

Myocardial Ischemia | Coronary Artery Disease | Coronary Disease | Chronic Total Occlusion of Coronary Artery | Coronary Restenosis | Vascular Disease | Coronary Artery Stenosis

United States
Yonsei University

Active, not recruiting

A Randomized Comparison of CLOpidogrel Monotherapy Versus Extended Dual-antiplatelet Therapy Beyond 12 Months After Implantation of Drug-eluting StEnts in High-risk Lesions or Patients; A-CLOSE Trial

Coronary Artery Disease | DES

Korea, Republic of
Bryan Allen
National Cancer Institute (NCI); Gateway for Cancer Research; Holden Comprehensive...

Active, not recruiting

A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme

Glioblastoma Multiforme

United States
Novartis

Terminated

Avoiding Cardiovascular Events Through Combination Therapy in Patients Living With Systolic Hypertension (ACCOMPLISH)

Hypertension

United States, Denmark, Finland, Norway, Sweden
Joseph J. Cullen, MD, FACS
National Cancer Institute (NCI); National Institutes of Health (NIH)

Active, not recruiting

A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme

Glioblastoma | Glioblastoma Multiforme | GBM

United States
H. Lee Moffitt Cancer Center and Research Institute
Novartis; Celgene Corporation

Active, not recruiting

Ofatumumab, High Dose Methylprednisolone, Ofatumumab and Lenalidomide Consolidative Therapy for Untreated CLL/SLL

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Institut de Recherches Internationales Servier
ADIR, a Servier Group company

Terminated

Efficacy and Safety of Atorvastatin + Perindopril Fixed-Dose Combination S05167 in Adult Patients With Arterial Hypertension and Dyslipidemia

Hypertension | Dyslipidemias

Georgia, Russian Federation, Ukraine
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Active, not recruiting

Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer

Prostate Cancer

United States, Canada
Memorial Sloan Kettering Cancer Center
Spectrum Pharmaceuticals, Inc

Active, not recruiting

Study of Captisol Enabled Melphalan and Pharmacokinetics for Patients With Multiple Myeloma or Light Chain Amyloidosis That Are Receiving an Autologous Transplant.

Multiple Myeloma | Amyloidosis

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Active, not recruiting

Hyperthermia and High Dose Rate Radiation Therapy in Treating Patients With Recurrent Prostate Cancer After Radiation

Recurrent Prostate Carcinoma

United States
Erasmus Medical Center
DUMAS is sponsored by an unrestricted grant from Thrombolytic Science International...

Completed

Dual Thrombolytic Therapy With Mutant Pro-urokinase and Low Dose Alteplase for Ischemic Stroke (DUMAS)

Ischemic Stroke

Netherlands
NewAmsterdam Pharma

Completed

A Dose-Finding Study in Japanese Patients to Evaluate the Effect of Obicetrapib as an Adjunct to Stable Statin Therapy.

Dyslipidemia | Hypercholesterolemia | High Cholesterol

Japan
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Active, not recruiting

Fulvestrant and/or Anastrozole in Treating Postmenopausal Patients With Stage II-III Breast Cancer Undergoing Surgery

Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Recurrent Breast Cancer | Estrogen Receptor-positive Breast Cancer | HER2-negative Breast Cancer | Invasive Lobular Breast Carcinoma | Invasive Ductal Breast Carcinoma

United States, Puerto Rico
Amicus Therapeutics

Active, not recruiting

Gene Therapy for Children With CLN3 Batten Disease

Batten Disease | CLN3

United States
Beijing Tiantan Hospital
Ministry of Science and Technology of the People's Republic of China

Active, not recruiting

Intensive Medical Therapy for High-risk Intracranial or Extracranial Atherosclerosis (INSPIRES)

Transient Ischemic Attack | Acute Stroke

China
The Third Xiangya Hospital of Central South University

Completed

Low-dose Quadruple Combination Therapy in Patients With Hypertension (QUADUAL)

Hypertension | Arterial Hypertension

China
Memorial Sloan Kettering Cancer Center
Sanofi; Columbia University; Medical College of Wisconsin; University of Rochester and other collaborators

Active, not recruiting

Study of the Impact of CD34+ Cell Dose on Absolute Lymphocyte Count Following High-Dose Therapy and Autologous Stem Cell Transplantation for Relapsed and Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Diffuse Large B-cell Lymphoma (DLBCL) | Relapsed Diffuse Large B-cell Lymphoma (DLBCL) | Refractory Diffuse Large B-cell Lymphoma (DLBCL)

United States
Helixmith Co., Ltd.

Completed

Safety and Efficacy Study for the Treatment of Painful Diabetic Neuropathy

Painful Diabetic Neuropathies

United States, Korea, Republic of
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Low Dose Radiation Therapy for Glioblastoma Multiforme

High Grade Glioma

United States
Memorial Sloan Kettering Cancer Center
Weill Medical College of Cornell University; University of Washington; H. Lee...

Active, not recruiting

A Phase 2 Multicenter Study of High Dose Chemotherapy With Autologous Stem Cell Transplant Followed by Maintenance Therapy With Romidepsin for the Treatment of T Cell Non-Hodgkin Lymphoma

T Cell Non-Hodgkin Lymphoma

United States
Institut du Cancer de Montpellier - Val d'Aurelle

Completed

Sphincter-preserving Surgery After Preoperative Treatment of Ultra-low Rectal Carcinoma (GRECCAR1)

Rectal Cancer

France
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI); NCIC Clinical Trials Group; Children's Oncology... and other collaborators

Active, not recruiting

High-Dose Interferon Alfa in Treating Patients With Stage II or Stage III Melanoma

Melanoma (Skin)

United States, Canada, Australia, South Africa
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy Regimens in Treating Patients With Limited-Stage Small Cell Lung Cancer Receiving Cisplatin and Etoposide

Lung Cancer

United States, Puerto Rico, Korea, Republic of, Israel
Basilea Pharmaceutica
ArQule, Inc. (a wholly owned subsidiary of Merck Sharp and Dohme, a subsidiary...

Completed

Phase 1/2 Study of Derazantinib (ARQ 087) in Adult Subjects With Advanced Solid Tumors With FGFR Genetic Alterations

Solid Tumor

United States, Italy
University of California, San Diego
National Cancer Institute (NCI)

Terminated

Allogeneic Stem Cell Transplant After ATG, High-Dose Melphalan, and Fludarabine for Patients With Breast Cancer

Breast Cancer

United States
University of California, San Diego
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

FRESH-DOSE: Families Responsibility Education Support Health-Dual Options for Sustained Effectiveness

Obesity | Overweight

United States
Rutgers, The State University of New Jersey
Rutgers Cancer Institute of New Jersey; Elekta Limited; Cianna Medical, Inc.

Completed

Accelerated Partial Breast Radiation Therapy Using High-Dose Rate Brachytherapy in Treating Patients With Early Stage Breast Cancer After Surgery (TRIUMPH-T)

Invasive Breast Carcinoma | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Estrogen Receptor Positive | Progesterone Receptor Positive | Ductal Breast Carcinoma In Situ

United States
Centre Hospitalier Universitaire de Saint Etienne
Institut de Cancérologie de la Loire

Completed

High Dose Therapy Followed by Autologous Transplantation for Myeloma Patients With Severe Renal Impairment (IRMYG)

Multiple Myeloma | Renal Failure

France, Belgium, Algeria, Lebanon
University of Florida
Janssen, LP

Completed

Switching From DAPT to Dual Pathway Inhibition With Low-dose Rivaroxaban in Adjunct to Aspirin in Patients With Coronary Artery Disease (SWAP-AC)

Coronary Artery Disease

United States
University Health Network, Toronto
Princess Margaret Hospital, Canada

Completed

5 Fraction Stereotactic Body Radiation Therapy for Oligometastases Regimen, for Extra-Cranial Oligometastases

Solid Tumors With Oligometastatic Spread

Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Active, not recruiting

Higher Per Daily Treatment-Dose Radiation Therapy or Standard Per Daily Treatment Radiation Therapy in Treating Patients With Early-Stage Breast Cancer That Was Removed by Surgery

Breast Cancer

United States, Canada, Israel, Hong Kong, Korea, Republic of, Singapore, Switzerland, Japan
Cancer Trials Ireland

Active, not recruiting

A Prospective Phase II Dose Escalation Study Using IMRT for High Risk N0 M0 Prostate Cancer. ICORG 08-17

Prostate Cancer

Ireland
Mayo Clinic
Regenerative Medicine Minnesota

Terminated

Patient-Derived Stem Cell Therapy for Diabetic Kidney Disease

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Diabetic Kidney Disease | Diabetic Nephropathies | Chronic Kidney Disease | Kidney Failure | Diabetic Nephropathy Type 2 | Kidney Insufficiency

United States
Rennes University Hospital

Completed

Trial Involving Subjects Over 70 Years of Age With Non Small-cell Lung Cancer of Stage IV and Comparing a "Classical" Strategy of Treatment Allocation, With an"Optimized" Strategy Allocating the Same Treatments (ESOGIA)

Non Small-cell Lung Cancer

France
AHS Cancer Control Alberta
Tom Baker Cancer Centre

Terminated

GEMHDM2014 : Gem-HDM HDT and ASCT for Relapsed/ Refractory Lymphoma (GEMHDM2014)

Follicular Lymphoma | Hodgkin's Lymphoma - Relapsed/Refractory | Non-Hodgkin's Lymphoma - Aggressive

Canada
Makerere University

Completed

Safety and Efficacy of High Dose Rifampicin in Tuberculosis (TB)-HIV Co-infected Patients on Efavirenz- or Dolutegravir-based Antiretroviral Therapy (SAEFRIF)

Tuberculosis

Uganda
Alessandro Pasqualotto
Hospital de Clinicas de Porto Alegre; Irmandade Santa Casa de Misericórdia... and other collaborators

Completed

Randomized Trial of Liposomal Amphotericin B for Histoplasmosis in AIDS Patients

AIDS | Histoplasmosis

Brazil
Janssen Research & Development, LLC

Completed

A Study of Abiraterone Acetate Plus Low-Dose Prednisone Plus Androgen Deprivation Therapy (ADT) Versus ADT Alone in Newly Diagnosed Participants With High-Risk, Metastatic Hormone-Naive Prostate Cancer (mHNPC)

Prostate Neoplasms

Canada, France, Poland, Ukraine, United Kingdom, China, Belgium, Spain, Argentina, Colombia, Israel, Mexico, Portugal, Bulgaria, Germany, Malaysia, Romania, South Africa, Turkey, Korea, Republic of, Japan, Australia, Netherlands, Sweden, New Zealand and more
Ripple Therapeutics Pty Ltd
Novotech (Australia) Pty Limited

Active, not recruiting

Safety and Efficacy of IBE-814 Intravitreal (IVT) Implant - A Sustained, Low Dose Dexamethasone Therapy

Diabetic Macular Oedema | Retinal Vein Occlusion With Macular Oedema

Australia, New Zealand, Hong Kong, Canada
German Oncology Center, Cyprus

Active, not recruiting

Hypo-Combi Trial: Hypofractionated EBRT Plus HDR-BT Boost for Prostate Cancer (Hypo-Combi)

Prostate Adenocarcinoma | Radiation Toxicity

Cyprus
Federal State Budget Institution Research Center...

Active, not recruiting

Efficacy, Safety, and Tolerability of Higher Doses Estrogen Therapy in Women With Premature Ovarian Insufficiency

Primary Ovarian Insufficiency

Russian Federation
Hanyang University Seoul Hospital
Abbott; Soon Chun Hyang University

Completed

Xience Registry In Complex Lesion of Acute Coronary Syndrome Patients witH Ticagrelor (RICH) (RICH)

Coronary Artery Disease | Acute Coronary Syndrome | Percutaneous Coronary Intervention

Korea, Republic of
Institut Cancerologie de l'Ouest
Hospices Civils de Lyon; Centre Antoine Lacassagne

Terminated

Phase-1 Study of Folinic Acid to Modulate MGMT Gene in Glioblastoma (FOLAGLI)

Glioblastoma | Grade IV Astrocytoma

France
Arbor Pharmaceuticals, Inc.

Completed

An Efficacy and Safety Study in Children 6 to Less Than 18 Years of Age With Hypertension

Hypertension

United States, Brazil, Turkey, Poland, Mexico, Colombia, Italy, Argentina, Bulgaria, Hungary, South Africa, Ukraine
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; NCIC Clinical... and other collaborators

Active, not recruiting

Surgery With or Without Docetaxel and Leuprolide or Goserelin in Treating Patients With High-Risk Localized Prostate Cancer

Prostate Cancer

United States, Canada
Technische Universität Dresden

Completed

Percutaneous High-dose Radiotherapy in Patients With Oligometastases of Prostate Carcinoma (Oli-P)

Prostate Cancer | Oligometastatic Disease

Germany
The Aurum Institute NPC
Johns Hopkins University; University of California

Completed

Safety Tolerability DDI Short Course Treatment of LTBI Infection With High-dose Rifapentine and Isoniazid or Standard Isoniazid Preventive Therapy in HIV+ Patients (DOLPHIN & DOLPHIN TOO) (IMPAACT4TB)

HIV Infections | Respiratory Tract Infections

South Africa
Dana-Farber Cancer Institute
Massachusetts General Hospital; Beth Israel Deaconess Medical Center

Terminated

CHOEP + High Dose Therapy + Auto SCT for T-Cell Lymphoma

T-cell Non-Hodgkin Lymphoma

United States

Search clinical trials for: high dose dual therapy

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