Search clinical trials for: oropharyngeal cancer

Total 86650 results

Robert L. Ferris, MD, PhD
Bristol-Myers Squibb

Active, not recruiting

Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer

Oropharynx Squamous Cell Carcinoma | Carcinoma, Squamous Cell of Head and Neck

United States
Thomas Jefferson University

Completed

Exercise Training and Behavioral Modification for the Improvement of Physical Activity in Head and Neck Cancer Patients Undergoing Cancer Treatment

Head and Neck Carcinoma | Lung Carcinoma | Oral Cavity Carcinoma | Paranasal Sinus Carcinoma | Stage III Laryngeal Cancer AJCC v8 | Stage IV Laryngeal Cancer AJCC v8 | Hypopharyngeal Carcinoma | Laryngeal Carcinoma | Stage IVA Laryngeal Cancer AJCC v8 | Stage IVB Laryngeal Cancer AJCC v8 | Stage IVC Laryngeal... and other conditions

United States
Jennifer Choe
Arcus Biosciences, Inc.

Withdrawn

A Study of Concurrent Chemoradiation in Combination With or Without PD1 Inhibitor AB122 Adenosine 2a Receptor / Adenosine 2b Receptor Inhibitor AB928 Therapies in Locally Advanced Head and Neck Cancers (PANTHEoN)

Head and Neck Cancer | Squamous Cell Carcinoma of Head and Neck | Oropharynx Cancer | Oral Cavity Cancer | Oropharynx Squamous Cell Carcinoma | Pharynx Cancer | Larynx Cancer | Hypopharynx Cancer | Oral Cavity Squamous Cell Carcinoma | Hypopharynx Squamous Cell Carcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers

Cervical Cancer | Anal Cancer | Oropharyngeal Cancer | Vulvar, Vaginal, Penile, Rectal Cancer | HPV Positive Cancer

United States
Turnstone Biologics, Corp.
Takeda

Terminated

Study of TBio-6517 Given Alone or in Combination With Pembrolizumab in Solid Tumors (RAPTOR)

Renal Cell Carcinoma | Cervical Cancer | Solid Tumor | Mesothelioma | Melanoma (Skin) | Oropharynx Cancer | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Microsatellite Stable Colorectal Cancer | Cutaneous Squamous Cell Carcinoma

United States, Canada, Korea, Republic of
Jonsson Comprehensive Cancer Center
AstraZeneca

Terminated

Stereotactic Body Radiation Therapy and Durvalumab With or Without Tremelimumab Before Surgery in Treating Participants With Human Papillomavirus Positive Oropharyngeal Squamous Cell Caner

Oropharyngeal Squamous Cell Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies

Cervical Cancer | Anal Cancer | Oropharyngeal Cancer | HPV Cancers | Vulvar, Vaginal, Penile, Rectal Cancer

United States
Nebraska Methodist Health System

Active, not recruiting

De-Escalation Protocol Of HPV Mediated Oropharyngeal Squamous Cell Carcinoma

Oropharynx Cancer | HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Clinical Stage

United States
The Netherlands Cancer Institute
AstraZeneca

Active, not recruiting

Olaparib and Radiotherapy in Head and Neck Cancer

Head and Neck Neoplasms | Carcinoma, Squamous Cell | Laryngeal Cancer Stage II | Laryngeal Cancer Stage III

Netherlands
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Active, not recruiting

Swallowing Outcomes and Circulating Tumor DNA in Patients With HPV Related Oropharyngeal Cancer Treated With Transoral Surgery and Reduced Intensity Adjuvant Therapy

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Oropharyngeal Human Papillomavirus-Positive Squamous...

United States
University of Michigan Rogel Cancer Center
National Cancer Institute (NCI); VA Ann Arbor Healthcare System

Active, not recruiting

Individualized Adaptive De-escalated Radiotherapy for HPV-related Oropharynx Cancer

Oropharynx Cancer

United States
Maastricht Radiation Oncology
Brigham and Women's Hospital; Princess Margaret Hospital, Canada

Active, not recruiting

Predicting Radiological Extranodal Extension in Oropharyngeal Carcinoma Patients Using AI (AI4rENE)

Head and Neck Carcinoma

Canada, Netherlands, United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck

Metastatic Squamous Cell Carcinoma of the Hypopharynx | Metastatic Squamous Cell Carcinoma of the Larynx | Metastatic Squamous Cell Carcinoma of the Oral Cavity | Metastatic Squamous Cell Carcinoma of the Oropharynx | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous... and other conditions

United States
University of Alberta

Completed

Staying Connected: a Mobile Health Study With the Noona® and Mobili-T® Systems

Oropharynx Cancer

Canada
Lawson Health Research Institute

Active, not recruiting

Primary Radiotherapy Versus Primary Surgery for HPV-Associated Oropharyngeal Cancer (ORATOR2)

Oropharyngeal Cancer

Canada, Australia
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Active, not recruiting

Radiation Therapy With Cisplatin or Cetuximab in Treating Patients With Oropharyngeal Cancer

Head and Neck Cancer | Precancerous Condition

United States, Canada
Mayo Clinic
National Cancer Institute (NCI)

Completed

Radiation Therapy and Docetaxel in Treating Patients With HPV-Related Oropharyngeal Cancer

Human Papillomavirus Infection | Stage IVA Oropharyngeal Squamous Cell Carcinoma | Stage IVB Oropharyngeal Squamous Cell Carcinoma | Stage I Oropharyngeal Squamous Cell Carcinoma | Stage II Oropharyngeal Squamous Cell Carcinoma | Stage III Oropharyngeal Squamous Cell Carcinoma

United States
University of Chicago
National Cancer Institute (NCI)

Active, not recruiting

Nab-paclitaxel and Carboplatin Followed by Response-Based Local Therapy in Treating Patients With Stage III or IV HPV-Related Oropharyngeal Cancer (OPTIMA)

Human Papilloma Virus Infection | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IVA Squamous Cell Carcinoma of the Oropharynx | Stage IVB Squamous Cell Carcinoma of the Oropharynx

United States
M.D. Anderson Cancer Center
Sanofi

Withdrawn

Phase 2 Study of Neoadjuvant SAR444245 Plus Cemiplimab in HPV Related Oropharynx Squamous Cell Carcinoma

Head and Neck Cancer | Oropharynx Cancer | Squamous Cell Carcinoma

United States
Hyunseok Kang, MD
NRG Oncology

Completed

Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin

Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IV Hypopharyngeal... and other conditions

United States
Klus Pharma Inc.

Completed

Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene

Cervical Cancer | Head and Neck Cancer | Mucoepidermoid Carcinoma | Pancreatic Cancer | Recurrent Prostate Cancer | Lung Cancer | Rectal Cancer | Solid Tumor | Prostate Cancer | Cholangiocarcinoma | Bile Duct Cancer | Recurrent Ovarian Carcinoma | Bladder Cancer | Skin Cancer | HER2-positive Breast Cancer | Rare Diseases | Colo-rectal Cancer and other conditions

United States
Icahn School of Medicine at Mount Sinai
Arizona State University; The Biodesign Institute

Active, not recruiting

The Quarterback Trial: Reduced Dose Radiotherapy for HPV+ Oropharynx Cancer

Squamous Cell Carcinomas

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer

Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Unresectable Head and Neck Squamous Cell Carcinoma | Unresectable Oropharyngeal... and other conditions

United States
University of Arizona
National Cancer Institute (NCI)

Completed

Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell Carcinoma

Head and Neck Cancer | Recurrent Head and Neck Squamous Cell Carcinoma | Oropharyngeal Cancer | HNSCC | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma | Stage IVA Nasal Cavity and... and other conditions

United States
Dana-Farber Cancer Institute

Active, not recruiting

Post-treatment Surveillance in HPV+ Oropharyngeal SCC

Oropharyngeal Squamous Cell Carcinoma | HPV

United States
University of Chicago

Completed

Pilot Study of Chemotherapy for HPV-Associated Oropharyngeal Cancer

Oropharyngeal Squamous Cell Carcinoma

United States
University of Michigan Rogel Cancer Center

Completed

Phase II Treatment Stratification Trial Using Neck Dissection-Driven Selection to Improve Quality of Life for Low Risk Patients With HPV+ Oropharyngeal Squamous Cell Cancer

Oropharyngeal Squamous Cell Cancer

United States
George Washington University

Active, not recruiting

Induction Chemotherapy Followed by Surgery for Locally Advanced Head and Neck Cancer

Head and Neck Cancer

United States
Region Örebro County
Värmland County Council, Sweden; Region Stockholm; Dalarna County Council, Sweden and other collaborators

Active, not recruiting

Circulating Biomarkers in Oropharyngeal Cancers (CIRCOS)

Oropharynx Cancer | Oropharynx Squamous Cell Carcinoma | Base of the Tongue Carcinoma | Tonsillar Cancer

Sweden
National Cancer Institute (NCI)

Completed

Ipilimumab, Cetuximab, and Intensity-Modulated Radiation Therapy in Treating Patients With Previously Untreated Stage III-IVB Head and Neck Cancer

Stage IVA Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVB Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVB Laryngeal Squamous Cell Carcinoma AJCC v7 | Stage IVB... and other conditions

United States
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IV Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma | Stage IVA Oropharyngeal Carcinoma AJCC v7 | Stage IVB Oropharyngeal Carcinoma AJCC v7

United States
Jonsson Comprehensive Cancer Center
Eli Lilly and Company

Terminated

Radiation Therapy and Cisplatin With or Without Cetuximab in Treating Patients With HPV Positive, KRAS-Variant Stage III-IV Oropharyngeal Squamous Cell Carcinoma

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage IV HPV-Mediated (p16-Positive)... and other conditions

United States
Monopar Therapeutics

Terminated

Clonidine HCl MBT vs. Placebo to Prevent Chemoradiotherapy-Induced Severe Oral Mucositis in Oropharyngeal Cancer. (VOICE)

Chemoradiotherapy-Induced Severe Oral Mucositis

United States, Spain, Germany, France, Puerto Rico
UNC Lineberger Comprehensive Cancer Center

Completed

Functional Sparing of Salivary Glands Using MRI Sialography for Patients Undergoing Definitive Radiation Therapy for Head and Neck Cancers of the Oropharynx

Head and Neck Cancer | Oropharynx Cancer | Xerostomia Due to Radiotherapy

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Withdrawn

Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced or Refractory Solid Tumors

Cancer
Universitätsklinikum Hamburg-Eppendorf
Charite University, Berlin, Germany; University Hospital Ulm; University Medical...

Active, not recruiting

Comparative Effectiveness Trial of Transoral Head and Neck Surgery Followed by Adjuvant Radio(Chemo)Therapy Versus Primary Radiochemotherapy for Oropharyngeal Cancer

Oropharyngeal Cancer

Germany
Sanford Health
Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab in Combination With CRT for LA-SCCHN

Head and Neck Cancer | Laryngeal Cancer | Oropharynx Cancer | Oral Cavity Cancer | Larynx Cancer | Squamous Cell Carcinoma | Hypopharynx Cancer

United States
The University of Texas Health Science Center,...
M.D. Anderson Cancer Center

Terminated

CytID Analysis of Oral Lesions

Oropharyngeal Cancer | Oral Cavity Cancer

United States
Emory University
National Cancer Institute (NCI); National Institutes of Health (NIH); Exelixis

Active, not recruiting

Pembrolizumab & Cabozantinib in Patients With Head and Neck Squamous Cell Cancer

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IV Hypopharyngeal Squamous Cell Carcinoma... and other conditions

United States
Rigshospitalet, Denmark
The Novo Nordic Foundation

Completed

Outpatient Ultrasound for the Diagnostic Work-up of Oropharynx Cancer

Oropharynx Cancer | Tonsil Cancer | Tonsil Hypertrophy | Tonsil Neoplasm | Tonsil Lymphoma | Base of Tongue Carcinoma | Oropharynx Neoplasm | Base of Tongue Tumor

Denmark
University Health Network, Toronto
National Institute on Deafness and Other Communication Disorders (NIDCD)

Completed

Physiological Flow of Liquids in Head and Neck Cancer Patients: A Pilot Study

Deglutition Disorders | Oropharynx Cancer

Canada
University of California, San Diego
Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma

Head and Neck Cancer | Head and Neck Neoplasms | Nasopharynx Cancer | Head and Neck Squamous Cell Carcinoma | Oropharynx Cancer | Oral Cavity Cancer | Larynx Cancer | HNSCC | Hypopharynx Cancer | Cutaneous Squamous Cell Carcinoma | Lip SCC | Sinonasal Carcinoma

United States
Celldex Therapeutics

Terminated

A Study of CDX-3379 and Cetuximab and in Patients With Advanced Head and Neck Squamous Cell Carcinoma

Advanced Head and Neck Squamous Cell Carcinoma

United States
Brigham and Women's Hospital

Active, not recruiting

Improving Detection and Early Action for HPV-positive Oropharynx Cancer (IDEA-HPV)

HPV Positive Oropharyngeal Squamous Cell Carcinoma

United States
Rigshospitalet, Denmark

Active, not recruiting

Functional Outcome After Treatment for Oropharyngeal Squamous Cell Carcinoma

Quality of Life | Pain | Oropharynx Cancer | Human Papilloma Virus | Swallowing Disorder | Saliva Altered

Denmark
National Cancer Institute (NCI)

Completed

M7824 in Subjects With HPV Associated Malignancies

Cervical Cancer | Anal Cancer | Oropharyngeal Cancer | Human Papilloma Virus | Vaginal or Penile Cancer

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Bupropion Hydrochloride or Patient's Choice for Smoking Cessation in Patients With Squamous Cell Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy

Nasopharyngeal Carcinoma | Current Smoker | Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Hypopharyngeal Squamous Cell Carcinoma | Laryngeal Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma

United States
Rigshospitalet, Denmark
Odense University Hospital; Aarhus University Hospital; Region Capital Denmark; Candys Foundation

Completed

Postoperative Pain, Why Still in Hospital and DAOH Following TORS for SCCUP & OSAS

Pain, Postoperative | Postoperative Pain | Analgesia | Surgery | Cancer of Head and Neck | Oropharyngeal Cancer | Carcinoma of Unknown Primary

Denmark
Institut Claudius Regaud
AstraZeneca

Completed

Cisplatin or ImmunoTHerapy in Association With Definitive Radiotherapy in HPV-related oropharyngEal Squamous Cell Carcinoma: a Randomized Phase II Trial. (CITHARE)

Oropharyngeal Squamous Cell Carcinoma

France
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Prepare to Care, A Supported Self-Management Intervention for Head and Neck Cancer CaregiversHead and Neck Cancer

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Caregiver | Salivary Gland Squamous Cell Carcinoma | Malignant Head and Neck Neoplasm | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Stage... and other conditions

United States

Search clinical trials for: oropharyngeal cancer

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