Search clinical trials for: pharmacokinetic

Total 12689 results

Forma Therapeutics, Inc.
Novo Nordisk A/S

Recruiting

A Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell Disease

Sickle Cell Disease

Lebanon, Canada, Kenya, United Kingdom
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of IBI356 in Healthy Participants and in Atopic Dermatitis Patients

Healthy Participants | Atopic Dermatitis Patients

China
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit

Not yet recruiting

Postpartum Primaquine in Breast Milk (PBC)

Postpartum Women

Thailand
Curon Biopharmaceutical (Shanghai) Co.,Ltd

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of CN201

Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

China
Changchun GeneScience Pharmaceutical Co., Ltd.
West China Hospital

Not yet recruiting

A Randomized, Double-blind, Placebo-controlled Phase II Clinical Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetic Profile of Genakumab Injection in Patients With Connective Tissue Disease-associated Interstitial Lung Disease

Systemic Sclerosis Associated Interstitial Lung Disease | Rheumatoid Arthritis Associated Interstitial Lung Disease (RA-ILD) | Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD)

China
GlaxoSmithKline

Not yet recruiting

A First Time in Human Study to Evaluate the Safety and Tolerability of GSK3996401 Following Dosing With GSK4347859 in Healthy Participants

Systemic Lupus Erythematosus

United Kingdom
Jiangsu Simcere Pharmaceutical Co., Ltd.
Shanghai Xianxiang Medical Technology Co., Ltd.

Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SIM0237 Alone or in Combination With BCG in NMIBC

Non-Muscle-Invasive Bladder Cancer (NMIBC)

China
Wave Life Sciences Ltd.

Recruiting

A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1) (RestorAATion-1)

Alpha-1 Antitrypsin Deficiency

United Kingdom
Ji Xing Pharmaceuticals Australia Pty Ltd
Novotech (Australia) Pty Limited

Recruiting

JX09 SAD/MAD in Healthy Participants

Resistant Hypertension

Australia
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

A Clinical Study to Compare the Safety and Pharmacokinetics of SHR-1314 Injection in Healthy Subjects at Different Specifications Devices

Moderate-to-Severe Plaque Psoriasis

China
IMBiologics Corp.

Not yet recruiting

A Study of IMB-101 in Healthy Volunteers and Participants With Rheumatoid Arthritis

Rheumatoid Arthritis
Pfizer

Recruiting

A Study to Understand the Effect of Multiple Ascending Doses of PF-07293893 in Healthy Adult Participants

Healthy Participants

Belgium
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Randomized, Double-Blind, Dose-Escalation, Placebo-Controlled Phase I Clinical Trial Investigating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Oral Doses of HRS-7085 Tablets in Healthy Subjects, With Assessment of Food Effects

Inflammatory Bowel Disease
Mabscale, LLC

Recruiting

Study, Evaluating Pharmacokinetics, Pharmacodynamics, Immunogenicity and Safety Profiles of Rituximab Compared to MabThera® in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Russian Federation
Mabwell (Shanghai) Bioscience Co., Ltd.

Recruiting

Study to Evaluate the Pharmacokinetic Characteristics, Safety, Tolerability, and Preliminary Efficacy of 9MW1911 in Patients With Chronic Obstructive Pulmonary Disease (COPD).

Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

China
Qilu Pharmaceutical Co., Ltd.

Recruiting

A Study Comparing Pharmacokinetic and Safety of QL2107 and Keytruda® (Marketed in China and the United States) in Healthy Adults

Tumor

China
Oregon Health and Science University
National Center for Advancing Translational Sciences (NCATS)

Not yet recruiting

Ashwagandha Pharmacokinetics Study in Older Adults

Healthy | Aging

United States
Keymed Biosciences Co.Ltd

Not yet recruiting

Study Evaluating the Pharmacokinetics of CM310 in Healthy Subjects

Healthy

China
GlaxoSmithKline
Medicines for Malaria Venture

Recruiting

A Study to Investigate the Safety of GSK4024484 in Healthy Adult Participants

Malaria, Falciparum

United Kingdom
Akeso

Not yet recruiting

A Study to Evaluate the Safety, Tolerance, Pharmacokinetics, and Preliminary Antineoplastic Activity of AK132 in Advanced Malignant Solid Tumor

Advanced Malignant Solid Tumor

China
Chiesi Farmaceutici S.p.A.

Recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis

Bronchiectasis

United Kingdom
scPharmaceuticals, Inc.

Recruiting

Pharmacokinetics and Pharmacodynamics of Subcutaneous vs Intravenous Furosemide in Healthy Volunteers

Heart Failure | Fluid Overload

United States
Central South University

Recruiting

Clinical Study of Individualized Vancomycin Dosing Based on Population PK Model

Severe Infection

China
Jasper Therapeutics, Inc.

Recruiting

Dose Escalation Trial Of Safety, Pharmacokinetic/Pharmacodynamic And Preliminary Clinical Activity of Briquilimab In Adult Patients With Chronic Spontaneous Urticaria (CSU) (BEACON)

Chronic Spontaneous Urticaria

United States, Germany
Terns, Inc.

Not yet recruiting

CARDINAL- A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of TERN-701 in Participants With Chronic Myeloid Leukemia

Chronic Myeloid Leukemia | Chronic Myeloid Leukemia, Chronic Phase

United States
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

A Clinical Trial Evaluated the Safety and Tolerability, Pharmacokinetic and Pharmacodynamics Profile, and Immunogenicity of a Single Dose of JS010 Injection in Healthy Subjects

Migraine

China
AbbVie

Recruiting

A Study to Assess the Safety, Pharmacokinetics, and Efficacy of Intravenous (IV) ABBV-303, as Monotherapy and in Combination With IV Infused Budigalimab (ABBV-181), in Adults With Advanced Solid Tumors

Solid Tumors

United States, Israel
JMackem Co., Ltd
Seoul National University Hospital

Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Oral Administration of AJH-2947 in Healthy Korean and/or Caucasian Adult Male Subjects

Diabetic Neuropathies | Neuropathic Pain | Post Herpetic Neuralgia

Korea, Republic of
Hinova Pharmaceuticals Inc.

Recruiting

A Phase I Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in mCRPC Patients

Metastatic Castration-resistant Prostate Cancer

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Monalizumab and MEDI5752 in Patients With MSI and/or dMMR Metastatic Cancer (MONAMI)

MSI | dMMR Colorectal Cancer

France
Azidus Brasil
Boya Bio Pharmaceutical Group Co Ltd

Not yet recruiting

Efficacy and Safety and Pharmacokinetics of Boya IVIG (Boya)

Primary Immunodeficiency Disease
Ionis Pharmaceuticals, Inc.

Recruiting

Orbit Study: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Intrathecally Administered ION356 in Participants With Pelizaeus Merzbacher Disease (PMD)

Pelizaeus-Merzbacher Disease

France, Netherlands
Kinnov Therapeutics

Not yet recruiting

A Study to Assess the Pharmacokinetic Profile of Prazosin and Cyproheptadine

Alcohol Use Disorder
Heinrich-Heine University, Duesseldorf

Recruiting

PRIMETEST II - Clinical Stage II A/B Seminoma Treated With RA-RPLND

Seminoma

Germany
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Safety, Tolerability, Drug Levels, Food, Formulation, and pH Effects on Relative Absorption of BMS-986465 and Its Active Derivative BMS-986464 in Healthy Participants

Healthy Participants

United States
Gubra A/S
Quotient Sciences

Recruiting

A First-In-Human Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GUB014295

Overweight | Healthy Volunteers

United Kingdom
Hillhurst Biopharmaceuticals, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

A Safety, Efficacy, and Pharmacokinetic (PK) Study of HBI-002, an Oral Carbon Monoxide (CO) Therapeutic, in Subjects With Sickle Cell Disease (SCD)

Anemia, Sickle Cell

United States
Jiangsu Gensciences lnc.

Recruiting

Phase 3 Clinical Project of Pegylated Recombinant Human Coagulation Factor VIII-Fc Fusion Protein

Severe Hemophilia A

China
AstraZeneca

Recruiting

Study to Assess the Pharmacokinetic Bioequivalence of Budesonide and Albuterol With an Alternate Propellant Compared to Current Propellant.

Heathy Participants

United States
Science Valley Research Institute
Biós Farmacêutica

Recruiting

Pharmacokinetic Aspects of 25-mg Estradiol Pellet in Climacteric Women (CLARA)

Menopause | Hypoestrogenism | Climacteric Syndrome

Brazil
Genentech, Inc.

Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Vixarelimab in Participants With Moderate to Severe Ulcerative Colitis (UC)

Ulcerative Colitis

United States, Poland
AstraZeneca

Recruiting

A Single and Multiple Ascending Dose Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD2389 in Healthy Participants

Healthy Participants

United States
PENTA Foundation
Baylor College of Medicine; Institut National de la Santé Et de la Recherche... and other collaborators

Not yet recruiting

Pharmacokinetics Safety and Acceptability of DRV/r for Children Living With HIV (UNIVERSAL2)

HIV Infections
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Population Pharmacokinetics of Paracetamol in Overweight and Obese Children (PARAENFO)

Obesity | Overweight

France
Bio-Thera Solutions

Recruiting

Assessment of Safety, Tolerability and Pharmacokinetics With BAT4706 and BAT1308 in Advanced Solid Tumors Patients

Advanced Solid Tumor

China
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

A Clinical Trail to Compare Pharmacokinetics of Two PEG-rhGH Injections With Different Preparations

Pediatric Growth Hormone Deficiency (PGHD)

China
Changchun GeneScience Pharmaceutical Co., Ltd.

Not yet recruiting

A Clinical Trial to Compare Pharmacokinetics of Two Different PEG-rhGH Preparations

Pediatric Growth Hormone Deficiency (PGHD)

China
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); National Institute...

Recruiting

Analysis of Cellular Kinases and Aging in PBMCs and Colorectal Tissue

HIV Infections | Aging

United States
Ikaria Bioscience Pty Ltd
SHANGHAI RONA Therapeutics Co.,Ltd.

Not yet recruiting

the Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects in Adult Subjects With Elevated LDL-C

To Reduce the LDL-C Level in Hypercholesteremia Patients
AstraZeneca
Parexel

Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD6234 After Repeat Dose Administration in Participants Who Are Overweight or Obese

Healthy Participants

United States, United Kingdom, Germany

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