Search clinical trials for: randomised double blind crossover trial

Total 47287 results

William Beaumont Army Medical Center

Recruiting

A Prospective Randomized Double Blinded Controlled Trial of Non-Operative Management of TFCC Injuries (TFCC)

Wrist Injuries | PRP

United States
WeiWei Zhan

Recruiting

A Multicenter Trial of PLA vs. Surgery for Treating PTMC

Thyroid Cancer | Treatment Related Cancer

China, Italy
SyneuRx International (Taiwan) Corp
Amarex Clinical Research

Recruiting

An Adaptive Phase II/III, Two-Part, Double-Blind, Randomized, Placebo-controlled, Dose-Finding, Multi-center Study of the Safety and Efficacy of NaBen®, as an Add-on Therapy With Clozapine, for Residual Symptoms of Refractory Schizophrenia in Adults

Refractory Schizophrenia

United States
VA Office of Research and Development

Recruiting

Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics (VA INTREPID)

Diabetes | Amputation | Osteomyelitis

United States
Sunnybrook Health Sciences Centre
Canadian Institutes of Health Research (CIHR)

Recruiting

Lithium for Fracture Treatment: a Double Blind Randomized Controlled Trial (LiFT) (LiFT)

Fractures

Canada
AgoneX Biopharmaceuticals, Inc.

Not yet recruiting

A Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Assess the Efficacy and Safety of Subcutaneous AGX-201 for Migraine Prophylaxis

Migraine Prophylaxis
Fundacion para la Formacion e Investigacion Sanitarias...

Completed

Randomized Double-blind Trial to Study the Benefit of Colchicine in Patients With Acutely Decompensated Heart Failure (COLICA)

HEART FAILURE

Spain
Hope Biosciences Stem Cell Research Foundation
Hope Biosciences

Completed

Randomized, Double-Blind Clinical Trial for Parkinson's Disease (Early and Moderate) (PD)

Parkinson Disease

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Subcutaneous (SC) Versus Pembrolizumab Intravenous (IV) Administered With Platinum Doublet Chemotherapy in Participants With Metastatic Squamous or Nonsquamous Non-Small Cell Lung Cancer (NSCLC) (MK-3475-A86)

Non-Small Cell Lung Cancer

Poland, United States, Brazil, France, Guatemala, Hungary, Japan, Korea, Republic of, Peru, Romania, Russian Federation, South Africa, Spain, Taiwan, Turkey, Ukraine
Escient Pharmaceuticals, Inc

Active, not recruiting

Phase 2a, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of EP262 in Subjects With Atopic Dermatitis (EASE)

Atopic Dermatitis

United States, Canada
China Medical University Hospital

Completed

The Safety and Efficacy Evaluation of XSLJZ in Advanced Hepatocellular Carcinoma Patients With Multiple Protein Kinase Inhibitor Therapy: A Randomized, Double-Blind, Controlled Trial

Hepatocellular Carcinoma

Taiwan
Appalachian State University

Completed

Improving Locomotor Learning With Brain Stimulation (ELLMITS)

Motor Learning

United States
M.D. Anderson Cancer Center

Active, not recruiting

Crossover Trial of Systemic Chemotherapy in Patients With Metastatic Well-Differentiated Mucinous Appendiceal Adenocarcinomas With Pseudomyxoma Peritonei

Gastrointestinal Neoplasms

United States
Najit Technologies, Inc.
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Trial of an Inactivated Yellow Fever Virus Vaccine

Yellow Fever

United States
Merit E. Cudkowicz, MD
Massachusetts General Hospital

Active, not recruiting

HEALEY ALS Platform Trial - Master Protocol

Amyotrophic Lateral Sclerosis

United States
General Committee of Teaching Hospitals and Institutes...

Active, not recruiting

A Comparative Study Between Ultrasound Guided Shoulder Block and Pericapsular Nerve Group Bock for Shoulder Arthroscopic Surgeries: Double Blinded Randomized Clinical Trial

Efficacy of PENG Block Managing Perioperative Pain With Shoulder Arthroscopy Surgeries | Efficacy of Shoulder Block in Managing Perioperative Pain With Shoulder Arthroscopy Surgeries

Egypt
Q32 Bio Inc.
Innovaderm Research Inc.

Active, not recruiting

Randomized, Double-Blind, Placebo-Controlled Phase 2a, Proof-of-Concept Trial of ADX-914 Phase 2a Trial for the Treatment of Severe Alopecia Areata (SIGNAL-AA)

Alopecia Areata

United States
University of Sao Paulo
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.; Conselho Nacional... and other collaborators

Enrolling by invitation

Ibogaine in the Treatment of Alcoholism: a Randomized, Double-blind, Placebo-controlled, Escalating-dose, Phase 2 Trial

Alcoholism

Brazil
James J. Irrgang
Brooke Army Medical Center; Wake Forest University

Terminated

Phase 1/2 Prospective Double-Blind Placebo-Controlled Randomized Clinical Trial of Losartan to Treat Grade II & III Hamstring Strains

Hamstring Injury

United States
VA Office of Research and Development

Terminated

Lithium for Suicidal Behavior in Mood Disorders (Li+)

Depressive Disorder | Bipolar Disorder | Suicide, Attempted | Suicide

United States
Second Xiangya Hospital of Central South University

Withdrawn

A Novel Application of 2% Lidocaine Injection for Male Rigid cycstoscopy-a Patient-blinded Randomised Trial

Bladder Cancer

China
National Institute of Allergy and Infectious Diseases...

Completed

A Phase 1, First-in-human, Double-blinded, Randomized, Placebo-controlled Trial of a Zika Virus Purified Inactivated Vaccine (ZPIV) With Alum Adjuvant in Healthy Flavivirus-naive and Flavivirus-Primed Subjects.

Zika Virus Infection

United States
UCB Pharma

Completed

A Multi-Centre, Randomized, Double-Blind, Placebo Controlled Pilot Trial to Assess the Efficacy, Safety, and Tolerability of SPM 927 in Subjects With Postherpetic Neuralgia (PHN).

Postherpetic Neuralgia
National Institute of Allergy and Infectious Diseases...
GlaxoSmithKline; PPD; Rho Federal Systems Division, Inc.; Immune Tolerance Network...

Active, not recruiting

Belimumab With Rituximab for Primary Membranous Nephropathy (REBOOT)

Nephrotic Syndrome | Membranous Nephropathy

United States, Canada
Denovo Biopharma LLC

Completed

A Biomarker-Guided, Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of Liafensine in Patients With Treatment-Resistant Depression (ENLIGHTEN)

Treatment Resistant Depression

United States, Canada
Dan Hasson
AFA Insurance; Stiftelsen Stressmottagningen

Completed

Possible Effects of the Dietary Supplement Magnesium Compared to Placebo

Health Promotion
AstraZeneca

Active, not recruiting

A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease (SERENA-4)

ER-Positive HER2-Negative Breast Cancer

Austria, Belgium, France, Germany, Italy, United Kingdom, United States, Canada, India, Taiwan, Russian Federation, Korea, Republic of, Hungary, Japan, Mexico, Turkey, China, Malaysia, Spain, Czechia, Portugal, Poland, Norway, Bulgaria, Slovaki... and more
NORCE Norwegian Research Centre AS
University of Bergen; University of Vienna

Active, not recruiting

Music for Autism (M4A) (M4A)

Autism Spectrum Disorder | Autism

Austria, Norway
Kanyos Bio, Inc., a wholly-owned subsidiary of...

Completed

Assessment of KAN-101 in Celiac Disease (ACeD)

Celiac Disease

United States
MYOS Corp
Citruslabs

Completed

A Randomized, Double-Blind, Controlled Trial to Assess the Efficacy of a Fortetropin Supplement in Improving Symptoms of Osteoarthritis

Osteoarthritis

United States
State University of New York at Buffalo

Terminated

Double Blinded Randomized Control Trial of Types of IVF in Children With DKA

Diabetic Ketoacidosis

United States
Göteborg University
Sahlgrenska University Hospital, Sweden

Terminated

Iodine Status in Swedish Lactating Women - Effect of Iodine Supplementation in the Thyroid Function of Mother and Infant

Lactation | Thyroid Gland; Node

Sweden
Odense University Hospital

Active, not recruiting

The DANish COronary DEcalcification (DANCODE) Trial (DANCODE)

Coronary Artery Disease

Denmark
Albireo

Completed

Double-blind, Randomised Study of A3384 in BAM/BAD

Bile Acid Malabsorption

Sweden, United Kingdom
PepsiCo Global R&D

Completed

A Prospective, Randomized, Placebo-controlled, Double-blind Study to Assess the Efficacy of Bacillus Coagulans Unique IS2 on Improving Bowel Movement Characteristics, Gastrointestinal-related Symptoms and Quality of Life in Healthy Adult Participants

Stool Frequency

Canada
Amgen

Completed

Apremilast as a Direct Treatment for Mild-to-moderate Plaque Psoriasis Versus Placebo: an Analysis of Clinical Safety and Efficacy (ADVANCE)

Psoriasis

United States, Canada
Rigshospitalet, Denmark

Terminated

A Randomized, Double-blinded, Clinical, Placebo-controlled Trial on the Effects of Therapy With Letrozole and hUman Choriongonadotropin in Male Hypogonadism Induced by Illicit Use of Anabolic Androgenic Steroids- The LUCAS Trial

Hypogonadotropic Hypogonadism | Hypogonadism | Hypogonadism, Male

Denmark
Indonesia University

Completed

EFFECTIVENESS AND SAFETY OF CREAM CONTAINING SPENT GRAIN WAX EXTRACT, ARGAN OIL, AND SHEA BUTTER POST-TRICHOLOROACETIC ACID 15% PEEL: RANDOMIZED, CONTROLLED, DOUBLE-BLIND, SPLIT-FACE CLINICAL TRIAL

Aging Disorder

Indonesia
Seed Health

Active, not recruiting

Randomized, Double-Blind Placebo-Controlled Trial to Assess Overall User Experience of a Synbiotic Vaginal Suppository

Vaginal Personal Care

United States
Annovis Bio Inc.
TFS Trial Form Support

Completed

A Double-blind Study to Investigate Efficacy and Safety of Buntanetap Compared With Placebo in Participants With Early PD

Parkinson's Disease, Idiopathic

United States, Spain, Poland, Germany, Hungary, Italy
Beijing Dongfang Biotech Co., Ltd.

Active, not recruiting

Influence of JY09 on Pharmacokinetics of Metformin , Rosuvastatin , and Digoxin and the QT Interval Study in Overweight Chinese Subjects

Diabetes Mellitus, Type 2 | Overweight

China
Population Council
University of Zimbabwe

Completed

A Crossover Acceptability Study Assessing a DPP Capsule for HIV and Pregnancy Prevention (952)

HIV Infections | Contraception

Zimbabwe
University of Oulu
Helsinki University Central Hospital

Active, not recruiting

Preemer Trial - Prophylactic Mesh Versus no Mesh in the Midline Emergency Laparotomy Closure for Prevention of Incisional Hernia: a Multi Center, Double-blind, Randomized Controlled Trial

Incisional Hernia | Emergency Laparotomy | Midline Laparotomy | Hernia Prevention

Finland
Biologische Heilmittel Heel GmbH

Completed

TRAUMED - a Clinical Trial in Acute Ankle Sprain (TRAUMED)

Ankle Sprain

Germany
Zealand University Hospital

Completed

Low-Intensity Extracorporeal Shock Wave Treatment for Erectile Dysfunction: A Randomized, Controlled, Double Blind Trial

Erectile Dysfunction

Denmark
Institut Curie
National Cancer Institute, France

Completed

ER-One: A Double-blind Trial of Erector Spinae Block (ESP) Versus Paravertebral Block (PVB) Before Breast Cancer Surgery (ER-One)

Breast Surgery

France
Centre for Addiction and Mental Health
Ottawa Heart Institute Research Corporation; Canadian Cancer Society (CCS)

Completed

Personalized Dosing of Nicotine Replacement (NRT to Effect)

Tobacco Use Disorder | Nicotine Dependence

Canada
Sanofi
Regeneron Pharmaceuticals

Completed

A Phase 4, Randomized, Double-blind, Placebo-controlled,Multicenter, Parallel-group Study of the Effect of Dupilumab on Sleep Disturbance in Patients With Uncontrolled Persistent Asthma (MORPHEO)

Asthma

Spain, United States, Argentina, Canada, Germany, Italy, Netherlands, Portugal, Russian Federation, Ukraine, United Kingdom
Rajavithi Hospital

Completed

Efficacy of Postoperative Pain Control Between Transarticular VS Periartiucular Multimodal Drug Infiltration in Total Hip Arthroplasty: Double-blinded Randomized Control Trial

Pain, Post Operative | Arthroplasty Complications

Thailand
AstraZeneca
The Cleveland Clinic; Concentrics Research LLC; Concentrics Research - STATKING... and other collaborators

Completed

Technology-Assisted Cholesterol Trial in Consumers (TACTiC) (TACTiC)

High Cholesterol

United States

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