Search clinical trials for: ALA

Total 255115 results

Merck Sharp & Dohme LLC

Terminated

A Study of the Efficacy and Safety of MK-0431D (a Fixed-dose Combination of Sitagliptin and Simvastatin) for the Treatment of Participants With Type 2 Diabetes Mellitus (T2DM) With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-266)

Type 2 Diabetes Mellitus
St Stephens Aids Trust
Bristol-Myers Squibb

Terminated

Pharmacokinetic Effect of Evotaz/Microgynon Co-administration

HIV

United Kingdom
Jilin University

Unknown

Marched Pair Study Conventional Doxorubicin(DOX) Versus Pegylated Liposomal Doxorubicin(PLD) Neoadjuvant Chemotherapy

Antineoplastic Combined Chemotherapy Protocols

China
National Cancer Institute (NCI)

Completed

Bevacizumab and Sorafenib in Treating Patients With Unresectable Stage III or Stage IV Malignant Melanoma

Stage IV Skin Melanoma | Recurrent Melanoma | Stage III Skin Melanoma

United States
University of Washington
National Cancer Institute (NCI)

Completed

Sirolimus, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Bladder Cancer

Stage III Bladder Cancer | Stage IV Bladder Cancer | Recurrent Bladder Carcinoma | Stage II Bladder Cancer

United States
National Cancer Institute (NCI)

Withdrawn

RO4929097 After Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma

Refractory Plasma Cell Myeloma | DS Stage I Plasma Cell Myeloma | DS Stage II Plasma Cell Myeloma | DS Stage III Plasma Cell Myeloma

United States
Red Cross War Memorial Childrens Hospital

Unknown

Efficacy of Combining Topical Antibiotic/Steroid/Moisturizer Therapy Compared to Active Comparator in Atopic Dermatitis.

Severe Atopic Dermatitis

South Africa
National Cancer Institute (NCI)

Terminated

Imatinib Mesylate With or Without Bevacizumab in Treating Patients With Metastatic or Unresectable Gastrointestinal Stromal Tumor (S0502)

Gastrointestinal Stromal Tumor

United States, Canada
Janssen Sciences Ireland UC

Completed

A Study in Healthy Female Participants to Investigate the Effect of JNJ-56136379 at Steady-state on the Single-dose Pharmacokinetics of Ethinylestradiol and Drospirenone (Oral Contraceptive) and on the Single-dose Pharmacokinetics of Midazolam (Probe Substrate for Cytochrome P450 3A4)

Healthy

Belgium
Hoffmann-La Roche

Completed

A Study on The Safety of Administering Rituximab at A More Rapid Rate in Patients With Rheumatoid Arthritis (RATE-RA)

Rheumatoid Arthritis

United States
National Cancer Institute (NCI)

Completed

Erlotinib Hydrochloride and Bevacizumab in Treating Patients With Stage IV Breast Cancer

Stage IV Breast Cancer | Recurrent Breast Carcinoma

United States
GlaxoSmithKline

Completed

Outcomes and Costs Associated With Initiating Maintenance Treatment With Fluticasone Propionate 250mcg/Salmeterol Xinafoate 50mcg Combination (FSC) Versus Anticholinergics Including Tiotropium (TIO) in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
St Stephens Aids Trust
Merck Sharp & Dohme LLC

Completed

Renal Integrase Study

HIV

United Kingdom
Marc Tewfik

Completed

Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery

Chronic Sinusitis

Canada
Susan Knox
GlaxoSmithKline; Corixa Corporation

Completed

Phase 2 Study of Bexxar in Relapsed/Refractory DLCL

Lymphoma

United States
Shanghai Public Health Clinical Center

Unknown

The Efficacy and Safety of R-EPOCH and R-CHOP Regimen for Patients With AIDS Associated CD20+ Diffuse Large B Lymphoma

To Evaluate the Efficacy and Safety of R-EPOCH and R-CHOP Regimen for Patients With AIDS Associated CD20+ Diffuse Large B Lymphoma
University of Florence
Merck Sharp & Dohme LLC

Unknown

Recovery of Muscle Function After Deep Neuromuscular Block by Means of Diaphragm Ultrasonography

Post-operative Residual Curarization

Italy
Juan A. Arnaiz

Unknown

Safety & Efficacy of Dual Therapy With Raltegravir/Lamivudine (RALAM)

AIDS

Spain
University of Hawaii
Gilead Sciences

Unknown

Sleep and Cognition After Atripla to Stribild Switch

HIV

United States
PETHEMA Foundation

Completed

LAL-BR/2001: Study Treatment to Low Risk ALL

Acute Lymphoblastic Leukemia

Spain
Centre Hospitalier Universitaire Vaudois
Hospices Civils de Lyon; University Hospital, Geneva; Central Hospital, Nancy...

Unknown

Antidepressants During Pregnancy and Lactation: Pharmacokinetics and Clinical Implications

Depressive Disorder | Lactation

France, Switzerland
Merck Sharp & Dohme LLC

Withdrawn

A Study of Single Dose Pain Therapy in Patients With Painful Diabetic Neuropathy (0000-115)

Painful Diabetic Neuropathy
Mingzhi Zhang
Shanxi Province Cancer Hospital; Wuhan University; Qingdao University; Wuhan Union... and other collaborators

Unknown

Treatment of Natural Killer/T Cell Lymphoma-I/II (CTTNKTL-I/II)

Nasal and Nasal-type NK/T-cell Lymphoma

China
Transdermal Therapeutics, Inc.
Albert Einstein College of Medicine; Montefiore Medical Center

Unknown

The Analgesic Activity of a Topical Formulation in Patients With Osteoarthritis of the Hands

Osteoarthritis of the Hands
University of Southern California
Novartis

Terminated

Panobinostat and Fluorouracil Followed By Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer Who Did Not Respond to Previous Fluorouracil-Based Chemotherapy

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Merck Sharp & Dohme LLC

Completed

A Study of Safety, Tolerability, and Immunogenicity of the MRKAd5 Gag/Pol/Nef Vaccine in Healthy Adults (V520-016)

HIV Infections | HIV-1
Fred Hutchinson Cancer Center
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

MsFLASH-03: Comparative Efficacy of Low-Dose Estradiol and Venlafaxine XR for Treatment of Menopausal Symptoms

Hot Flashes | Menopause | Vasomotor Disturbance

United States
First Affiliated Hospital Xi'an Jiaotong University

Unknown

Effects of Different Doses of Dexmedetomidine on Postoperative Cognitive Dysfunction in Elderly Hypertensive Patients

Postoperative Cognitive Dysfunction
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Followed by Melphalan and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Acute Myeloid Leukemia

Leukemia

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy, Surgery, and Radiation Therapy in Treating Children With Advanced Soft Tissue Sarcoma

Sarcoma

Puerto Rico, United States, Switzerland
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

High-Dose Cholecalciferol in Treating Patients Receiving Combination Chemotherapy and Bevacizumab as First-Line Therapy For Metastatic Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer

United States
University of California, San Francisco

Completed

Comparison of Pain of Conventional to Buffered Local Anesthesia During Injection in Pediatric Dental Patients (BufferDent)

Pain

United States
Universitaire Ziekenhuizen KU Leuven

Unknown

Optimization of Procedural Sedation Protocol Used for Dental Care Delivery in People With Mental Disability (OptiSeDent)

Dental Care for Disabled

Belgium
Vertex Pharmaceuticals Incorporated

Completed

A Phase 1 Study to Examine the Drug-Drug Interaction of Ciprofloxacin, Itraconazole, and Rifampin on the Combination of Lumacaftor With Ivacaftor in Healthy Adult Subjects

Cystic Fibrosis

United States
Scottish Cancer Therapy Network

Completed

Tamoxifen, Ovarian Ablation, and/or Combination Chemotherapy in Treating Premenopausal Women With Stage I, Stage II, or Stage IIIA Invasive Breast Cancer

Breast Cancer

United Kingdom
National Cancer Institute (NCI)

Completed

A Phase I, Pharmacological, and Biological Study of OSI-774 in Combination With FOLFOX 4 (5-FU, Leucovorin, and Oxaliplatin) and Bevacizumab (Avastin) in Patients With Advanced Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
The University of New South Wales

Completed

Combination Chemotherapy With or Without Gemtuzumab Ozogamicin or Tipifarnib in Treating Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Myelodysplastic Syndromes | Leukemia

United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Combination Chemotherapy With or Without Radiation Therapy and Peripheral Stem Cell Transplant in Treating Children With Hodgkin's Lymphoma

Lymphoma

United Kingdom, Ireland
Yale University

Completed

Sequential High-Dose Chemotherapy and Stem Cell Transplantation in Treating Patients With Chemotherapy-Sensitive Metastatic Breast Cancer

Breast Cancer

United States
Seattle Children's Hospital
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Trial of Early Aggressive Drug Therapy in Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis | Juvenile Rheumatoid Arthritis | Juvenile Chronic Polyarthritis

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy Compared With Hormone Therapy in Treating Patients With Recurrent, Stage III, or Stage IV Endometrial Cancer

Endometrial Cancer

United States, Canada
Washington University School of Medicine
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Treatment of Acute Sinusitis

Acute Respiratory Infections | Acute Rhinosinusitis

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Compare The Ability of Different Anti-HIV Drugs to Decrease Viral Load After Nelfinavir (an Anti-HIV Drug)Treatment Failure

HIV Infections

United States, Puerto Rico
Pfizer

Completed

Investigational Agent AG-013736 In Combinations With Standard Of Care Treatments For Patient's With Advanced Solid Tumor

Neoplasms

Poland, United States, Spain
GlaxoSmithKline

Completed

A Placebo-controlled Study to Investigate the Safety, and Pharmacokinetics of Oral GSK626616AC in Healthy Subjects

Healthy Subjects | Anaemia

Australia
University of Sao Paulo

Completed

Four Interventions in the Management of Psychomotor Agitation, Safety and Efficacy Evaluation

Psychomotor Agitation

Brazil
Research in Real-Life Ltd
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Device Mixing in Asthma, a General Practice Research Database Study (EBsalbutamol)

Asthma

United Kingdom
Makerere University
Health Research Board, Ireland

Unknown

Drug Interaction Between Coartem® and Nevirapine, Efavirenz or Rifampicin in HIV Positive Ugandan Patients

HIV Infections | Tuberculosis

Uganda
King Faisal University

Completed

Aminophylline and Cognitive Function After Sevoflurane Anaesthesia

Anaesthesia

Saudi Arabia
University of Washington

Unknown

Role of CYP2B6, CYP3A4, and MDR1 in the Metabolic Clearance of Methadone

Substance-Related Disorders

United States

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