Clinical Trials Sponsored by CDG Therapeutics, Inc.

Total 3011 results

Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Completed

Pharmacokinetics and Safety of rFVIIIFc Manufactured at 15,000 L (15K) Scale (Elevate)

Severe Hemophilia A

United States, Australia, New Zealand
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Completed

Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Recombinant Coagulation Factor VIII Fc Fusion Protein (rFVIIIFc) in Previously Treated Pediatric Subjects With Hemophilia A (Kids ALONG)

Hemophilia A

United States, Poland, United Kingdom, Netherlands, South Africa, Hong Kong, Australia, Ireland
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Completed

Study of Recombinant Coagulation Factor IX Fc Fusion Protein, BIIB029, in Previously Treated Pediatric Participants With Hemophilia B (Kids B-LONG)

Hemophilia B

United States, United Kingdom, South Africa, Netherlands, Ireland, Australia
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Terminated

Fc factOrs and Real-World hemophiliA Patient-ReporteD Outcomes (FORWARD)

Hemophilia A | Hemophilia B

United States
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Completed

Study of Recombinant Factor IX Fc Fusion Protein (rFIXFc) in Participants With Hemophilia B

Severe Hemophilia B

Sweden, United States, France, Italy, Russian Federation, United Kingdom, Germany, China, Poland, Japan, Australia, Brazil, Canada, India, South Africa, Hong Kong, Belgium
Johannes Gutenberg University Mainz
Leap Therapeutics, Inc.

Unknown

DKN-01 Inhibition in Advanced Liver Cancer

Hepatocellular Carcinoma

Germany
F-star Therapeutics, Inc.
PRA Health Sciences

Completed

A Fixed-Sequence, Drug-Drug Interaction Study Between Multiple Oral Doses of Inarigivir Soproxil and a Single Oral Dose of Midazolam in Healthy Subjects

Drug Interaction Potentiation

Netherlands
National University Hospital, Singapore
Karyopharm Therapeutics Inc

Completed

Phase I Study of KPT330 in Asian Patients

Solid Tumors

Singapore
Larimar Therapeutics, Inc.
Children's Hospital of Philadelphia

Completed

A Study to Assess Variation in Potential Biomarkers in Friedreich Ataxia

Friedreich Ataxia

United States
F-star Therapeutics, Inc.
PRA Health Sciences

Terminated

Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic Treatment Naive Subjects Infected With Hepatitis B Virus

Hepatitis B | Hepatitis B, Chronic | HBV

Hong Kong
Acorda Therapeutics
Prometrika, LLC; BCS Consulting, Inc.

Completed

An Open Label, Proof of Concept Study to Evaluate the Effects of Dalfampridine Withdrawal on Gait and Balance Parameters in Subjects With Multiple Sclerosis (MS)

Multiple Sclerosis

United States
Vidac Pharma
PharPoint Research, Inc.; Therapeutics, Inc.; Medistat Ltd., Israel

Completed

Study to Evaluate the Efficacy, Safety, and Tolerability of Topical VDA-1102 Ointment in Subjects With Actinic Keratosis (Phase2b)

Actinic Keratosis

United States
Kona Research Center
Integrative Therapeutics, Inc.; Bioenergy Life Science, Inc.

Completed

Treatment of Chronic Fatigue Syndrome and Fibromyalgia With D-ribose- a Multicenter Study

Fibromyalgia | Chronic Fatigue Syndrome

United States
Kenneth Krantz, MD, PhD
FHI Clinical, Inc.

Not yet recruiting

SLV213 Treatment in Ambulatory COVID-19 Patients

Covid19
University of Colorado, Denver
Pfizer; Criterium, Inc.; Cascadian Therapeutics Inc.

Completed

Tucatinib, Palbociclib and Letrozole in Metastatic Hormone Receptor Positive and HER2-positive Breast Cancer

Breast Cancer

United States
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum; Syntonix Pharmaceuticals, Inc.

Completed

Phase I/IIa Study of FIXFc in Hemophilia B Patients

Hemophilia B

United States
Bausch Health Americas, Inc.
Galderma R&D; Oceana Therapeutics, Inc.

Completed

A Randomized, Blinded, Multicenter Study to Evaluate NASHA/Dx for the Treatment of Fecal Incontinence

Fecal Incontinence

United States, Germany, Sweden, United Kingdom
Vanderbilt-Ingram Cancer Center
Astex Pharmaceuticals, Inc.; Forma Therapeutics, Inc.

Withdrawn

ASTX727 and FT-2102 in Treating IDH1-Mutated Recurrent/Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemia

Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome
Galera Therapeutics, Inc.
INC Research Australia Pty Ltd; Nucleous Network

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of Orally-administered GC4702 in Healthy Volunteers

Healthy Volunteer

Australia
Immune-Onc Therapeutics
Regeneron Pharmaceuticals

Completed

First-in-human Study of IO-108 as Single Agent and in Combination With a PD-1 Immune Check Point Inhibitor in Patients With Advanced Solid Tumors

Solid Tumor, Adult

United States
iN Therapeutics Co., Ltd.

Recruiting

A MAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers and PHN Patients.

Pain | Osteoarthritis | Chronic Pain | Neuropathic Pain | Post Herpetic Neuralgia

Australia
iN Therapeutics Co., Ltd.

Completed

A SAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers

Pain | Osteoarthritis

Australia
Rempex (a wholly owned subsidiary of Melinta Therapeutics...
Innovative Medicines Initiative; Universitätsklinikum Köln

Completed

Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Minocin (Minocycline) for Injection in Healthy Adults

Normal Healthy Volunteers

Netherlands
Durata Therapeutics International BV (an Affiliate...

Withdrawn

Dalbavancin vs Comparator in Pediatric Subjects With Acute Hematogenous Osteomyelitis (AHOM)

Osteomyelitis
Rempex (a wholly owned subsidiary of Melinta Therapeutics...
Innovative Medicines Initiative; Universitätsklinikum Köln

Terminated

Evaluate Safety and Pharmacokinetics of Minocin (Minocycline) for Injection in Subjects With Renal Insufficiency

Renal Insufficiency, Chronic | Healthy Subjects | Renal Insufficiency, Acute

Germany
Aeon Therapeutics (Shanghai) Co., Ltd.
Renmin Hospital of Wuhan University; Eureka Therapeutics Inc.

Terminated

Clinical Study of ET1402L1-CAR T Cells in AFP Expressing Hepatocellular Carcinoma

Liver Neoplasms | Hepatocellular Carcinoma | Liver Cancer | Metastatic Liver Cancer

China
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Eli Lilly and Company; Genentech, Inc.; Kazia... and other collaborators

Recruiting

Genetic Testing in Guiding Treatment for Patients With Brain Metastases

Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Brain | NTRK Family Gene Mutation | CDK Gene Mutation | PI3K Gene Mutation | ROS1 Gene Mutation | KRAS G12C Mutation

United States
Ocular Therapeutix, Inc.
Duke University; Fortrea

Recruiting

Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration

Neovascular Age-Related Macular Degeneration

United States
Midwest Eye Institute
Ocular Therapeutix, Inc.

Terminated

Assessing the Efficacy and Safety of DEXTENZA in Pseudo Phakic Patients Undergoing Gas Bubble Repair and Laser Following Retinal Detachment

Retinal Detachment

United States
Grene Vision Group
Ocular Therapeutix, Inc.

Completed

The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus In-office Post-Op Day 1

Cataract

United States
The Cleveland Clinic
Ocular Therapeutix, Inc.

Enrolling by invitation

Dextenza in the Post-op Management of Vitreoretinal Surgeries

Ocular Inflammation | Post-operative Pain | Vitreoretinal Surgery | Post-Operative Inflammation

United States
OncXerna Theraputics, Inc.
Merck Sharp & Dohme LLC

Completed

An Open Label Study of Bavituximab and Pembrolizumab in Advanced Gastric and GEJ Cancer Patients

Gastric Cancer | GastroEsophageal Cancer

Korea, Republic of, United Kingdom, Taiwan, United States
Artery Therapeutics, Inc.
National Institute on Aging (NIA)

Recruiting

Safety and Pharmacokinetics of Single Ascending Doses and Multiple Ascending Doses of CS6253 in Healthy Volunteers

Alzheimer's Disease

Spain
Carmot Australia First Pty Ltd
Carmot Therapeutics, Inc.

Recruiting

Phase 1 Study of CT-996 in Overweight/Obese Participants and Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes | Overweight or Obesity

Australia
Aardvark Therapeutics, Inc.
Children's Hospital Colorado; Stanford University

Recruiting

A Study of Oral ARD-101 in Patients With Prader-Willi Syndrome

Prader-Willi Syndrome

United States
Carmot Therapeutics, Inc.
Carmot Australia First Pty Ltd

Recruiting

A Study of CT-388 in Otherwise Healthy Overweight and Obese Adults and Patients With Type 2 Diabetes Mellitus

Diabetes

Australia, Mexico
Anewsha Therapeutics Inc.
University of Michigan; Biologics Consulting

Not yet recruiting

(CBDRA60) to Prevent or Reduce Symptoms of COVID-19 and Prevention of Post-Acute Sequelae of SARS-CoV-2 Infection PASC

COVID-19 | SAR

United States
Anthos Therapeutics, Inc.
The TIMI Study Group; Fortrea

Active, not recruiting

Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation (AZALEA-TIMI 71)

Stroke | Atrial Fibrillation (AF)

United States, Canada, Czechia, Hungary, Korea, Republic of, Poland, Taiwan
Neomatrix Therapeutics, Inc.
United States Department of Defense

Active, not recruiting

Phase 1 Healthy Volunteer Burn Therapy Study

Burns

United States
Vinbiocare Biotechnology Joint Stock Company
Arcturus Therapeutics, Inc.

Completed

The ARCT-154 Self-Amplifying RNA Vaccine Efficacy Study (ARCT-154-01) (ARCT-154-01)

COVID-19 Vaccines

Vietnam
Jiangsu Simcere Pharmaceutical Co., Ltd.
G1 Therapeutics, Inc.

Completed

Evaluation of TRILACICLIB in Chinese Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC) for Chemotherapy-induced Myelosuppression, Antitumor Effects of Combination Regimens, and Safety in a Real-world Study

Extensive-stage Small-cell Lung Cancer

China
Partner Therapeutics, Inc.
United States Department of Defense

Completed

Study of Sargramostim in Patients With COVID-19 (iLeukPulm)

COVID-19 | SARS-CoV-2

United States
Healthcare Innovation Technology Lab
Curio Digital Therapeutics, Inc.

Active, not recruiting

Curio Digital Therapy for the Treatment of Post-partum Depression (SuMMER)

PostPartum Depression

United States
Aardvark Therapeutics, Inc.
University of California, San Diego

Completed

Study to Evaluate ARD-101 in Adults With Obesity

Obesity

United States
SCRI Development Innovations, LLC
Novartis; Onyx Therapeutics, Inc.

Completed

Study of the Combination of Panobinostat and Carfilzomib in Patients With Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

United States
The Lymphoma Academic Research Organisation
Karyopharm Therapeutics Inc

Completed

A Phase Ib Study of Oral Selinexor in Adult Patients With Relapsed/Refractory B-cell Lymphoma Receiving R-DHAOx or R-GDP (SELINDA)

B-cell Lymphoma

Belgium, France
University of California, Los Angeles
INSYS Therapeutics Inc

Completed

Characterization of the Analgesic Effect of CBD in Healthy, Normal Volunteers

Pain

United States
Matthew Ingham
Takeda; Karyopharm Therapeutics Inc

Withdrawn

Selinexor in Combination With Ixazomib for the Treatment of Advanced Sarcoma

Sarcoma | Ewing Sarcoma | Liposarcoma | Alveolar Soft Part Sarcoma | Malignant Peripheral Nerve Sheath Tumors

United States
NovaDigm Therapeutics, Inc.
United States Department of Defense

Completed

Effect of Adjuvant & Route of Administration on Safety & Immunogenicity of NDV-3 Vaccine

Candidiasis | Staphylococcal Infections | Yeast Infections

United States
Clarus Therapeutics, Inc.
Celerion; Syneos Health; ARUP Laboratories

Completed

Assessment of Blood From Men Receiving Oral TU in Various Collection Tubes

Hypogonadism, Male

United States

Clinical Trials Sponsored by CDG Therapeutics, Inc.

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Australia

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Rare Diseases

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