Search clinical trials for: EGFR activating mutations

Total 2740 results

Taipei Veterans General Hospital, Taiwan
National Taiwan University Hospital; China Medical University Hospital; Tri-Service... and other collaborators

Unknown

Genius Study Study to Compare Efficacy and Safety of Gefitinib/ Pemetrexed With Pemetrexed Alone as Maintenance Therapy in Patients With Stage IV EGFR Mutation Negative or T790M Single Mutation Who Respond to Pemetrexed/ Platinum as First-line Therapy

NSCLC

Taiwan
National Cancer Institute (NCI)

Terminated

Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage IV Breast Cancer | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB... and other conditions

United States
Indiana University School of Medicine
Genentech, Inc.

Completed

Pilot Study Using Neoadj Chemo-Rad & EGFR-tyrosine Kinase Inhibitor for Potentially Resectable Pancreatic Cancer

Pancreatic Cancer

United States
Bracco Diagnostics, Inc

Terminated

Kidney Damage In Patients With Severe Fall In eGFR

Coronary Artery Stenosis

Canada
Amgen

Completed

Study of Panitumumab Efficacy in Patients With Recurrent and/or Metastatic Head and Neck Cancer (SPECTRUM)

Recurrent and/or Metastatic Head and Neck Cancer
US Oncology Research
Quintiles, Inc.

Completed

Biomarker Analysis for Patients With Metastatic Colorectal Cancer (MCC)

Colorectal Neoplasms | Advanced Metastatic Colorectal Cancer

United States
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Second Affiliated Hospital...

Unknown

Intermittent and Maintenance of Erlotinib in Combination With Pemetrexed/Carboplatin in Ⅲb/IV Non Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Mutation

Lung, Carcinoma
Betta Pharmaceuticals Co., Ltd.

Completed

Dose Escalation Of Icotinib In Previously Treated Patients With Routine Dose

Non-small Cell Lung Cancer

China
Betta Pharmaceuticals Co., Ltd.

Completed

Icotinib Combined With WBRT For NSCLC Patients With Brain Metastases and EGFR Mutation

Non-small Cell Lung Cancer | Brain Metastases

China
Betta Pharmaceuticals Co., Ltd.

Completed

Safety and Efficacy Study of Icotinb in Non-small Cell Lung Cancer (NSCLC) Patients (ICOGEN)

Non-small Cell Lung Cancer

China
Seoul St. Mary's Hospital
Novartis

Unknown

Prospective Investigation of Dynamics of ABL Mutations in Imatinib Failed CML Patients Treated With Nilotinib (AMICAN)

Chronic Myeloid Leukemia

Korea, Republic of
Abramson Cancer Center of the University of Pennsylvania
National Cancer Institute (NCI)

Unknown

Sunitinib Before and After Surgery in Treating Patients With Stage IV Kidney Cancer

Kidney Cancer

United States
Amgen

Completed

Evaluating Panitumumab (ABX-EGF) Monotherapy in Patients With Metastatic Colorectal Cancer Following Treatment With Fluoropyrimidine, Irinotecan, and Oxaliplatin Chemotherapy

Colorectal Cancer | Metastatic Cancer
University Hospital Birmingham

Unknown

Different Factors Affecting Patients With Newly Diagnosed Bladder Cancer

Bladder Cancer

United Kingdom
Boehringer Ingelheim

Completed

A Phase II Trial of Afatinib(BIBW 2992) in Third-line Treatment for Patients With Stage IIIB/IV Adenocarcinoma of the Lung Harbouring Wild-type Epidermal Growth Factor Receptor[EGFR]

Carcinoma, Non-Small-Cell Lung

Korea, Republic of
Zhejiang University

Unknown

Continuation of TKI With or Without Chemotherapy Beyond Gradual Progression

Non Small Cell Lung Cancer

China
Memorial Sloan Kettering Cancer Center
Boehringer Ingelheim; National Comprehensive Cancer Network

Withdrawn

Afatinib In Combination With Cisplatin Or Carboplatin + Pemetrexed In Patients With EGFR-Mutant Lung Cancers Undergoing Definitive Chemoradiation

Non-small Cell Lung Cancer
Medical Research Council

Completed

Study of Tumor Tissue Testing in Selecting Treatment for Patients With Metastatic or Locally Advanced Colorectal Cancer

Colorectal Cancer

United Kingdom
Sidney Kimmel Cancer Center at Thomas Jefferson...
National Cancer Institute (NCI)

Unknown

Gene Expression in Predicting Response to Paclitaxel in Patients With Breast Cancer

Breast Cancer
University of Sheffield

Unknown

Genes That Affect Disease Outcome in Patients With Metastatic Colorectal Cancer

Colorectal Cancer
Ulsan University Hospital
AstraZeneca

Unknown

Efficacy of EGFR TKIs in Patients With Rare EGFR-mutated NSCLC

Lung Neoplasms

Korea, Republic of
National University Hospital, Singapore

Unknown

A Retrospective Molecular Epidemiology Study in Singapore Patients With Advanced Non Small Cell Lung Cancer (NSCLC) of Adenocarcinoma Histology to Assess Epidermal Growth Factor Receptor (EGFR) Mutation Status

NSCLC

Singapore
Xinjiang Medical University

Unknown

Erlotinib Intercalated With Chemotherapy Versus Erlotinib as First Line Treatment in Stage IIIB/IV NSCLC Patients With EGFR Mutation

Non-Small Cell Lung Cancer

China
Seoul National University Hospital

Unknown

Analysis of Plasma Tumor DNA in Lung Cancer Patients

Non Small Cell Lung Cancer Patients

Korea, Republic of
National Taiwan University Hospital

Unknown

Gene Mutations in Non-Small Cell Lung Cancer Cells

Carcinoma, Non-Small-Cell Lung

Taiwan
Boehringer Ingelheim

Terminated

Phase II Trial of BIBW 2992 (Afatinib) in Genetically Pre-screened Cancers With EGFR and/or HER2 Gene Amplification.

Neoplasms

United States, Taiwan
Assistance Publique - Hôpitaux de Paris

Completed

Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (DVDA)

Cardiomyopathy | Arrhythmogenic Right Ventricular Dysplasia

France
Millennium Pharmaceuticals, Inc.

Completed

Study of MLN4924, a Novel Inhibitor of Nedd8 Activating Enzyme, in Adult Patients With Lymphoma or Multiple Myeloma

Lymphoma | Multiple Myeloma | Hodgkin Lymphoma | Hematologic Malignancies

United States
National Taiwan University Hospital

Unknown

A Pilot Study on ALK Gene Mutations in Neuroblastoma

Neuroblastoma

Taiwan
Novartis Pharmaceuticals

Completed

Six Months Efficacy and Safety of Aliskiren Therapy on Top of Standard Therapy, on Morbidity and Mortality in Patients With Acute Decompensated Heart Failure (ASTRONAUT)

Acute Decompensated Heart Failure | Congestive Heart Failure

Colombia, Czech Republic, India, Italy, Belgium, Turkey, Argentina, France, Germany, Israel, Spain, Canada, Taiwan, United States, Singapore, Russian Federation, Philippines, Slovakia, Sweden, Hungary, Finland, Poland, Romania, Brazil
Sun Yat-sen University

Completed

Prophylactic EVOZAC® Calming Skin Spray for EGFR-TKIs Associated Rash Eruption in NSCLC

Non-small Cell Lung Cancer

China
AstraZeneca

Completed

Retrospective Study in a NSCLC M+ p (Ca_Pulmon)

EGFR Mutated Non-small Cell Lung Cancer Patients

Spain
AstraZeneca

Completed

Epidemiological and Scientific Evaluation of EGFR Mutation Status in Patients With Newly Diagnosed Locally Advanced or m (REASON)

Newly Diagnosed Locally Advanced or Metastatic Non-small Cell Lung Cancer

Germany
AbbVie (prior sponsor, Abbott)

Completed

A Prospective, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate Efficacy and Safety of Atrasentan, Including Thoracic Bioimpedance, in Type 2 Diabetic Subjects With Nephropathy

Diabetic Nephropathy | Chronic Kidney Disease

United States
Memorial Sloan Kettering Cancer Center

Completed

Proximal Molecular Effects of Concurrent Chemoradiotherapy on Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma

United States
Genmab

Completed

Zalutumumab in Patients With Non-curable Head and Neck Cancer

Head and Neck Cancer | Squamous Cell Cancer

Sweden, United Kingdom, France, Hungary, Canada, Brazil, Belgium, Lithuania, Russian Federation, Serbia, Estonia, Poland
Centre Hospitalier Universitaire Dijon

Unknown

Clinical and Molecular Characterisation of Orofaciodigital Syndromes and Other Clinical Phenotypes Secondary to Mutations in the OFD1 Gene (OFD1)

Orofaciodigital Syndromes

France
Bracco Diagnostics, Inc

Completed

Kidney Damage in Patients With Normal eGFR

Coronary Artery Stenosis

United States
Children's Cancer and Leukaemia Group

Unknown

Erlotinib Alone or in Combination With Radiation Therapy in Treating Young Patients With Refractory or Relapsed Malignant Brain Tumors or Newly Diagnosed Brain Stem Glioma

Brain and Central Nervous System Tumors

United Kingdom, Ireland
Lawrence Livermore National Laboratory at University...
National Cancer Institute (NCI)

Unknown

Prostate Cancer Screening and Dietary Heterocyclic Amines in African American Men

Prostate Cancer

United States
Sheba Medical Center

Unknown

An Open Label Study of BIBW 2992/Afatinib in Advanced Non-Small Cell Lung Cancer Patients Pre-treated With Erlotinib or Gefitinib

NSCLC

Israel
The Christie NHS Foundation Trust

Unknown

Study of DNA Mutations in Predicting the Effect of External-Beam Radiation Therapy in Patients With Early Breast Cancer, Localized Prostate Cancer, or Gynecological Cancer

Sarcoma | Cervical Cancer | Breast Cancer | Ovarian Cancer | Fallopian Tube Cancer | Prostate Cancer | Vulvar Cancer | Endometrial Cancer | Vaginal Cancer | Primary Peritoneal Cavity Cancer

United Kingdom
The University of New South Wales

Completed

Combination Chemotherapy With or Without Gemtuzumab Ozogamicin or Tipifarnib in Treating Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Myelodysplastic Syndromes | Leukemia

United Kingdom
University College London Hospitals

Completed

Carboplatin or Docetaxel in Treating Women With Metastatic Genetic Breast Cancer

Breast Cancer | Hereditary Breast/Ovarian Cancer (brca1, brca2) | brca1 Mutation Carrier | brca2 Mutation Carrier

Australia, Israel, United Kingdom, Spain, Sweden, Portugal
University of Alabama at Birmingham
National Cancer Institute (NCI)

Withdrawn

Celecoxib in Preventing Cancer in Patients at High Risk for Ovarian Epithelial Cancer Who Are Undergoing Prophylactic Oophorectomy

Ovarian Cancer | brca1 Mutation Carrier | brca2 Mutation Carrier

United States
Leeds Cancer Centre at St. James's University Hospital

Unknown

Identifying Gene Mutations in Patients With Melanoma and in Families With a History of Hereditary Melanoma

Melanoma (Skin) | Hereditary Multiple Melanoma

United Kingdom
Leeds Cancer Centre at St. James's University Hospital

Unknown

Study of Families With Melanoma

Melanoma (Skin)

United Kingdom
Leeds Cancer Centre at St. James's University Hospital

Unknown

Answering Questions About Vitamin D Supplementation and Sun Exposure in Patients Who Have Undergone Surgery for Stage IB, Stage II, or Stage IIIA Melanoma

Melanoma (Skin)

United Kingdom
Cancer Research Centre at Weston Park Hospital

Unknown

Studying Patterns, Causes, and Control of Disease in Patients With Lung Cancer in the North Trent (England) Region

Lung Cancer

United Kingdom
Leeds Cancer Centre at St. James's University Hospital

Completed

Alemtuzumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia in Partial Remission or Complete Remission

Leukemia

United Kingdom

Search clinical trials for: EGFR activating mutations

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