Search clinical trials for: human pharmacology

Total 25629 results

Glaxo Wellcome

Completed

A Pilot Study To Evaluate the Effect of Retrovir (Zidovudine: AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Associated Dementia and Neuromuscular Diseases

HIV Infections | Neuromuscular Diseases | AIDS Dementia Complex

United States
Schering-Plough

Completed

Safety and Effectiveness of PEG-Intron in HIV-Infected Patients

HIV Infections

United States, Puerto Rico
National Center for Research Resources (NCRR)
Juvenile Diabetes Research Foundation

Unknown

Modification of the "Edmonton Protocol" to Allow for Successful Islet Transplantation From a Single Pancreas and Extension of the "Edmonton Protocol" to Kidney Transplant Recipients

Diabetes Mellitus

United States
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase I/II Study of Human Anti-Cytomegalovirus (CMV) Monoclonal Antibody MSL-109 in Newborns With Symptomatic Congenital CMV Infection Without Central Nervous System Disease

Cytomegalovirus Infections
ICOS Corporation
Suntory Pharmaceutical

Terminated

Safety and Efficacy of Recombinant Human Platelet-Activating Factor Acetylhydrolase for the Treatment of Severe Sepsis

Sepsis

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Education Program to Promote Female Condom Use

HIV Infections

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Improving Gait in Patients With Spinal Cord Injuries

Spinal Cord Injuries

United States
Lederle Laboratories

Completed

An Open-Label, Crossover Study to Assess the Effect of Food on the Oral Bioavailability and Pharmacokinetic Profile of 3'-Deoxy-3'-Fluorothymidine (FLT) in Asymptomatic Human Immunodeficiency Virus (HIV)-Infected Subjects

HIV Infections

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Bone Development in Adolescent Girls: Effects of Calcium and Exercise

Osteoporosis

United States
Sandoz

Completed

A Pilot Study to Evaluate the Effects of Subcutaneously Administered Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor in Pediatric HIV-Infected Patients With Neutropenia Secondary to Azidothymidine

HIV Infections | Cytopenias

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Increased Access to Emergency Contraceptive Pills

Sexually Transmitted Diseases | Pregnancy

United States
Glaxo Wellcome

Completed

Treatment and Suppression of Hairy Leukoplakia in ARC Patients With Oral Acyclovir (ACV)

HIV Infections | Leukoplakia, Hairy

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Prosthetic Limbs After Leg Amputation: Alternative Method of Socket Design

Amputation

United States
Pfizer

Completed

A Comparison of Fluconazole and Amphotericin B in the Treatment of Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States, Canada
Research Institute for Genetic and Human Therapy

Completed

Safety and Effectiveness of Combining Hydroxyurea (HU) With Didanosine (ddI) and Stavudine (d4T) for Treatment of HIV-Infected Adults

HIV Infections

United States
Hoffmann-La Roche

Completed

An Open-Label, Multicenter Study to Evaluate the Safety and Tolerability of Dideoxycytidine (ddC) in Patients With AIDS or Advanced ARC Who Previously Demonstrated Intolerance to Zidovudine (AZT) in Protocol N3300 or N3492

HIV Infections

United States
United Biomedical

Completed

A Phase I Safety and Immunogenicity Trial of UBI HIV Lipopeptide Immunotherapeutic P3C541b in HIV-1 Seropositive Human Subjects

HIV Infections

United States
United Biomedical

Completed

A Phase I/II Safety and Immunogenicity Trial of UBI Microparticulate Monovalent (HIV-1 MN) Branched Peptide Vaccine in HIV-1 Seronegative Human Subjects

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

A Study to Compare the Effectiveness of Two Anti-HIV Drug Combinations

HIV Infections

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Migraine and Recurrent Abdominal Pain in Children

Abdominal Pain | Migraine

United States
Eunice Kennedy Shriver National Institute of Child...
National Institute of Nursing Research (NINR)

Completed

HIV Symptom Management Program for African American Mothers

HIV Infections

United States
Glaxo Wellcome

Completed

The Antiviral Efficacy of Concurrent Zidovudine and 2',3'-Dideoxyinosine or 2',3'-Dideoxycytidine in Patients With Human Immunodeficiency Virus Disease

HIV Infections

United States, Puerto Rico, Australia
Interferon Sciences

Completed

Double-Blind, Randomized, Dose Ranging Study of Alferon LDO (Low Dose Oral Interferon Alfa-n3 (Human Leukocyte Derived)) in HIV+ Subjects

HIV Infections

United States
The Immune Response Corporation

Completed

A Multicenter, Double-Blind, Phase III, Adjuvant-Controlled Study of the Effect of 10 Units of HIV-1 Immunogen (Remune) Compared to Incomplete Freund's Adjuvant (IFA) Alone Every 12 Weeks on AIDS-Free Survival in Subjects With HIV Infection and CD4 T-Lymphocytes Between 300 and 549 Cells/microL Rega

HIV Infections

United States
National Center for Research Resources (NCRR)
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Study of Gonadotropin-Releasing Hormone Pulse Frequency in Sexual Maturation and in the Menstrual Cycle

Precocious Puberty | Hypogonadism

United States
Eunice Kennedy Shriver National Institute of Child...
Baylor College of Medicine

Completed

Nutritional Aspects of Rett Syndrome

Rett Syndrome
Eunice Kennedy Shriver National Institute of Child...
Baylor College of Medicine

Completed

Study of Cardiac and Paroxysmal Abnormalities in Rett Syndrome

Rett Syndrome
Merck Sharp & Dohme LLC

Unknown

The Safety and Effectiveness of Indinavir Plus Ritonavir Plus Two NRTIs in HIV-Infected Patients Who Need Early Intervention Treatment

HIV Infections

United States
Abgenix

Completed

A Blinded Study Comparing the Safety and Efficacy of a Fully Human Anti-IL8 Monoclonal Antibody (ABX-IL8) to Placebo in Patients With Chronic Bronchitis and COPD

Pulmonary Disease, Chronic Obstructive | Bronchitis, Chronic

United States
Eunice Kennedy Shriver National Institute of Child...
Children's National Research Institute

Terminated

Phase I Pilot Study of Liver-Directed Gene Therapy for Partial Ornithine Transcarbamylase Deficiency

Ornithine Transcarbamylase Deficiency Disease
XOMA (US) LLC

Completed

Safety and Efficacy of a Monoclonal Antibody for Treatment of Rheumatoid Arthritis.

Rheumatoid Arthritis

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

A Mother's Role in Delaying Onset of Sexual Activity in Her Children

Child Behavior | Adolescent Behavior

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Using fMRI to Evaluate Instructional Programs for Children With Developmental Dyslexia

Developmental Dyslexia

United States
Interferon Sciences

Completed

Double-Blind, Randomized, Placebo-Controlled Study of Low Dose Oral Interferon Alfa-n3 (Human Leukocyte Derived) in ARC Patients

HIV Infections

United States
Eunice Kennedy Shriver National Institute of Child...
National Institute of Mental Health (NIMH)

Unknown

Valproate Response in Aggressive Autistic Adolescents

Autism

United States
Eunice Kennedy Shriver National Institute of Child...
University of Washington

Unknown

Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders

Wiskott-Aldrich Syndrome | Leukocyte Adhesion Deficiency Syndrome | X-Linked Agammaglobulinemia | X-Linked Hyper IgM Syndrome

United States
National Center for Research Resources (NCRR)
Genentech, Inc.

Completed

Growth Hormone Use in Cystic Fibrosis - a Multicenter Study

Cystic Fibrosis

United States
Triangle Pharmaceuticals

Unknown

A Safety Study to Evaluate 12 Weeks of Treatment with Clevudine in Patients Infected with Hepatitis B Virus.

Hepatitis B

United States, Canada, China, France, Singapore
Eunice Kennedy Shriver National Institute of Child...
Johns Hopkins University

Completed

Study of the Pathogenesis of Rett Syndrome

Rett Syndrome
Sandoz

Completed

A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients With Cytopenia

HIV Infections | Cytopenias

United States
Pfizer

Completed

A Comparison of the Safety and Effectiveness of Fluconazole or Clotrimazole in the Treatment of Fungal Infections of the Mouth and Throat in Patients With AIDS

HIV Infections | Candidiasis, Oral

United States
National Center for Research Resources (NCRR)

Unknown

Linkage and Identification of (a) Candidate Gene(s) for Tooth Disorders

Anodontia

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Achilles Tendon Lengthening in Patients With Diabetes to Prevent Foot Ulcers

Diabetes Mellitus | Foot Ulcer | Peripheral Neuropathy

United States
Eunice Kennedy Shriver National Institute of Child...
Nationwide Children's Hospital

Completed

Randomized Study of Succimer (Dimercaptosuccinic Acid) on Growth of Lead-Poisoned Children

Lead Poisoning
Pfizer

Completed

Phase I Study of the Clinical Pharmacology of Azithromycin in Buffy Coat of HIV-Infected Subjects.

HIV Infections | Bacterial Infections

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Constraint-Based Therapy to Improve Motor Function in Children With Cerebral Palsy

Cerebral Palsy | Motor Deficits

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Emergency Contraception (ECP): Reducing Unintended Pregnancies

Pregnancy | Contraception

United States
Sandoz

Completed

A Phase I/II Trial to Assess the Safety and Tolerance of Escalating Doses of a Human Anti-Cytomegalovirus Monoclonal Antibody (SDZ MSL-109) in Patients With the Acquired Immunodeficiency Syndrome and CMV Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Lederle Laboratories

Completed

An Ascending, Single Oral Dose Pharmacokinetic Study of 3'-Deoxy-3'-Fluorothymidine (FLT) in Asymptomatic Human Immunodeficiency Virus (HIV)-Infected Subjects

HIV Infections

United States
National Center for Research Resources (NCRR)
Tulane University School of Medicine

Completed

Phase III Randomized Study of High Vs Standard Dose of Interferon Alfa for Chronic Hepatitis C

Hepatitis C

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