Search clinical trials for: MRA (Tocilizumab)

Total 6109 results

Hoffmann-La Roche

Completed

A Study to Evaluate Glofitamab as Single Agent Administered After Pretreatment With Obinutuzumab in Chinese Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Lymphoma

China
Hoffmann-La Roche

Terminated

A Study of RO7172508 in Patients With Locally Advanced and/or Metastatic CEA-Positive Solid Tumors

Solid Tumors

Spain, Belgium, Denmark, Canada
Hoffmann-La Roche

Completed

Characterization of Non-Steroidal Anti-Inflammatory Drug (NSAID) Intake in Rheumatoid Arthritis (RA) Participants on Tocilizumab (RoACTEMRA®) Treatment (CONIFER)

Rheumatoid Arthritis

Germany
Hoffmann-La Roche

Terminated

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Ankylosing Spondylitis Who Have Failed Treatment With NSAIDs

Spondylitis, Ankylosing

Belgium, Czech Republic, France, Germany, Italy, Poland, Spain, United States, Canada, South Africa, United Kingdom, Russian Federation, Australia, Bulgaria, India, Lithuania, Brazil, Slovakia
Rennes University Hospital

Completed

Comparative Study of Non-enhanced Versus Contrast Enhanced MR Angiography in Peripheral Arterial Disease on a 3T MR Scanner. (AngioIRMNative)

Peripheral Arterial Disease

France
Hoffmann-La Roche

Recruiting

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

Spain, Australia, Germany, United States, Italy, United Kingdom, France
Guerbet

Completed

DOTAREM®-Enhanced MRA Compared to GADOVIST®-Enhanced MRA in Patients With Abdominal or Lower Limb Arterial Diseases

Peripheral Arterial Disease

France
Alain Algazi
Genentech, Inc.

Recruiting

Preoperative Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck

Carcinoma | Cancer | Head and Neck Cancer | Squamous Cell Carcinoma

United States
Hoffmann-La Roche

Completed

A Study Of Tocilizumab in Patients With Moderate to Severe Active Rheumatoid Arthritis Who Have an Inadequate Response to or Are Unable to Tolerate Biologic and Non-Biologic Disease-modifying Antirheumatic Drugs (DMARDs)

Rheumatoid Arthritis

United States
University of Michigan Rogel Cancer Center

Completed

Trastuzumab and Pertuzumab in Combination With Tocilizumab in Subjects With Metastatic HER2 Positive Breast Cancer Resistant to Trastuzumab

Breast Cancer

United States
GI Alliance
Sonic Incytes

Not yet recruiting

Validation Study of the Velacur System in Comparison to MRE & MRI-PDFF in Patients With (Suspected) Liver Disease

Non-alcoholic Fatty Liver Disease (NAFLD)

United States
Burnasyan Federal Medical Biophysical Center

Completed

A Study of the Effectiveness of an Off Label Mefloquine Use for the Treatment of Patients With COVID19

Pneumonia, Viral | Respiratory Failure

Russian Federation
Case Western Reserve University

Completed

AIDS 347: IL-6 Blockade in Treated HIV Infection (IL-6)

HIV Infections

United States
Oslo University Hospital
University of Oslo; Norwegian University of Science and Technology; St. Olavs... and other collaborators

Completed

Effect of the Interleukin-6 Receptor Antagonist Tocilizumab in Non-ST Elevation Myocardial Infarction

Non-ST Elevation Myocardial Infarction

Norway
Centre Hospitalier Universitaire Dijon

Completed

Evaluation of Tocilizumab as an add-on Therapy to Corticoids in Giant Cell Arteritis: Proof of Concept Study. (HORTOCI)

Giant Cell Arteritis

France
Pfizer

Completed

Clinical Study to Evaluate Pharmacokinetics and Safety of PF-06700841 After Single and Multiple Oral Doses as Modified Release Formulations

Healthy Participants

United States
Genentech, Inc.

Active, not recruiting

A Study of Runimotamab in Participants With Locally Advanced or Metastatic HER2-Expressing Cancers

Solid Tumors

United States, Italy, Korea, Republic of, Spain, Denmark, Taiwan, Australia, France, Netherlands, United Kingdom, Singapore, Belgium, Japan, Canada
Ain Shams University
Misr International University

Completed

Comparison of Tocilizumab Versus Tocilizumab/Infliximab in Patients With COVID-19-associated Cytokine Storm Syndrome

Covid19 | Corona Virus Infection | Cytokine Storm

Egypt
Spanish Foundation of Rheumatology
Roche Farma, S.A

Unknown

Uncontrolled Study to Evaluate Efficacy of Tocilizumab in Patients With Moderate or Severe Rheumatoid Arthritis

Arthritis, Rheumatoid

Spain
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Active, not recruiting

Mechanisms of Cardiac Dysfunction in HIV and the Effect of Statins: A Cardiac MRI Study

HIV Infections

United States, South Africa
Assistance Publique Hopitaux De Marseille

Unknown

A Trial Using ANAKINRA, TOCILIZUMAB Alone or in Association With RUXOLITINIB in Severe Stage 2b and 3 of COVID19-associated Disease (INFLAMMACOV)

Covid19

France
University of Ulm

Completed

Critically Ill ICU Patients Under Casirivimab- and/or Tocilizumab Application (CasiTocCOVID)

COVID-19 | Critically Ill | Outcome, Fatal | Interleukin 6 | Tocilizumab

Germany
NYU Langone Health

Terminated

Ferric Carboxymaltose to Improve Skeletal Muscle Metabolism in Heart Failure Patients With Functional Iron Deficiency

Iron-deficiency

United States
Rigshospitalet, Denmark

Completed

Acute Exercise and NK Cell Regulation in Tissue and Circulation After IL-6R Blockade

Appetitive Behavior | Physical Stress | Interleukin-6 Inhibition

Denmark
Hoffmann-La Roche

Completed

A Study of RO6958688 in Participants With Locally Advanced and/or Metastatic Carcinoembryonic Antigen Positive Solid Tumors

Solid Tumors

United States, Denmark, Spain, Canada, France, Netherlands, Italy
University of Edinburgh

Unknown

PET/MR Imaging In Patients With Infective Endocarditis

Infective Endocarditis

United Kingdom
National Institute on Alcohol Abuse and Alcoholism...

Recruiting

Development Of Neuroimaging Methods To Assess The Neurobiology Of Addiction

Normal Physiology

United States
Assistance Publique Hopitaux De Marseille

Unknown

Comparison of Both Metabolic and Functional Effects Induced by Two Neuromuscular Electrical Stimulation Protocols: A Comprehensive Approach Using Magnetic Resonance Imaging and Spectroscopy

Healthy

France
Rigshospitalet, Denmark

Completed

Ectopic Adipose Tissue, Exercise Training and IL-6

Adiposity

Denmark
Christian Hassager

Completed

IL-6 Inhibition for Modulating Inflammation After Cardiac Arrest (IMICA)

Systemic Inflammatory Response Syndrome | Heart Arrest | Out-Of-Hospital Cardiac Arrest

Denmark
University Hospital, Antwerp

Completed

Self-Reported Versus Objective Measured Compliance With Oral Appliance Therapy for Obstructive Sleep Apnea Hypopnea Syndrome

OSAHS

Belgium
Medical University of Warsaw

Recruiting

Tocilizumab in Corticosteroid-Resistant Graves' Orbitopathy (Thyroid Eye Disease)

Thyroid Eye Disease | Ophthalmopathy | Orbitopathy, Graves

Poland
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

"Comparison of the Efficacy and Safety of Adalimumab to That of Tocilizumab in Severe Uveitis of Behçet's Disease" (UVB)

Behcet's Uveitis
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7443904 in Combination With Glofitamab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin

United States, Denmark, Italy, France, Australia, United Kingdom
Hoffmann-La Roche

Completed

A Study to Evaluate Efficacy of Tocilizumab Administered as Monotherapy or in Combination With Methotrexate and/or Other Disease Modifying Antirheumatic Drugs (DMARDs) in Rheumatoid Arthritis (RA) Participants

Rheumatoid Arthritis

Italy
University of California, Los Angeles
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Recruiting

Quantifying Body Composition and Liver Disease in Children Using Free-Breathing MRI and MRE

NAFLD | NASH - Nonalcoholic Steatohepatitis

United States
University of Aberdeen
NHS Grampian

Completed

Persistent Symptoms and Early Incomplete Recovery After Acute Stress-induced Cardiomyopathy: Is There Ongoing Heart Distress? The HEROIC Study (HEROIC)

Tako-tsubo Cardiomyopathy

United Kingdom
Sonic Incytes

Active, not recruiting

The Sonic Incytes Liver Incytes System, Evaluation of Liver Fibrosis and Steatosis Versus MRE and MRI PDFF

Liver Fibroses | Non-Alcoholic Fatty Liver Disease (NAFLD) | Non-Alcoholic Steatohepatitis (NASH) | Liver Steatoses

United States
Vastra Gotaland Region
Karolinska University Hospital; The Swedish Research Council; Uppsala University...

Recruiting

TocIlizumab in Chronic Antibody-mediated Rejection in Kidney Transplant Recipients (INTERCEPT)

Antibody-mediated Rejection

Sweden
Hoffmann-La Roche

Completed

A Study of Tocilizumab With or Without Methotrexate in Patients With Rheumatoid Arthritis.

Rheumatoid Arthritis

Slovakia
Ablynx

Completed

A Phase IIb Study for ALX-0061 Monotherapy in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Czechia, Bulgaria, Germany, Mexico, Poland, Romania, Serbia, Spain, Hungary, United States, Belgium, Georgia, Moldova, Republic of, North Macedonia
Hoffmann-La Roche

Completed

A Study of Tocilizumab Added to DMARDs in Patients With Moderate to Severe Rheumatoid Arthritis and an Inadequate Response to DMARDs.

Rheumatoid Arthritis

Russian Federation
Hoffmann-La Roche

Terminated

A Study of RoActemra/Actemra (Tocilizumab) in Combination With DMARDs Versus Current Best Practice DMARD Therapy in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Finland
National Taiwan University Hospital

Unknown

CE-MRA Using Gadovist in Comparison to IA DSA Using Ultravist

Magnetic Resonance Angiography | Angiography, Digital Subtraction

Taiwan
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Completed

MRI Study With Ferumoxytol in Assessing Early Response in Patients With Glioblastoma Multiforme Receiving Temozolomide and Radiation Therapy

Adult Brain Glioblastoma

United States
Shengjing Hospital

Recruiting

MRE for Assessment of Histopathological Growth Patterns in Colorectal Liver Metastases

Metastatic Colorectal Cancer

China
Assiut University

Completed

Role of Positron Emission Tomography/ Computed Tomography (PET/CT) and in Bone Metastases. (PET/CT)

Bone Metastases

Egypt
FMH College of Medicine and Dentistry

Completed

TOCILIZUMAB - An Option for Patients With COVID-19 Associated Cytokine Release Syndrome; A Single Center Experience

Covid19

Pakistan
Hellenic Institute for the Study of Sepsis

Completed

Personalised Immunotherapy for SARS-CoV-2 (COVID-19) Associated With Organ Dysfunction (ESCAPE)

Virus Diseases | COVID-19 | Corona Virus Infection | Macrophage Activation Syndrome

Greece
Regeneron Pharmaceuticals
Sanofi

Completed

Single-dose Study to Describe the Pharmacodynamics (PD) and Safety of Sarilumab (REGN88/SAR153191) and Tocilizumab in Adults With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States

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