Clinical Trials Sponsored by Baker Heart Research Institute

Total 757 results

H. Lee Moffitt Cancer Center and Research Institute
Bayer

Completed

Pre-operative 5-Fluorouracil (5-FU) and Sorafenib With External Radiation in Locally Advanced Rectal Cancer

Rectal Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute
Bayer

Completed

Phase II Trial Of ZK-EPO (ZK 219477) (Sagopilone) In Metastatic Melanoma

Melanoma

United States
H. Lee Moffitt Cancer Center and Research Institute
Bayer

Terminated

Depocyt® With Sorafenib in Neoplastic Meningitis

Neoplastic Meningitis

United States
Blood Systems Research Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Transfusion-Associated Microchimerism in Individuals Receiving a Blood Transfusion After a Traumatic Injury

Wounds and Injuries | Blood Transfusion | Chimerism

United States
Blood Systems Research Institute
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Detailed Evaluation of Microchimerism

Wounds and Injuries | Blood Transfusion | Chimerism | Hematopoiesis

United States
Carelon Research
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Long-term Outcomes of Children With Hypoplastic Left Heart Syndrome and the Impact of Norwood Shunt Type (SVRIII)

Heart Defects
Kansas City Heart Rhythm Research Foundation
Montefiore Medical Center; Texas Cardiac Arrhythmia Research Foundation; Kansas... and other collaborators

Not yet recruiting

The ORCHESTRATE-Myocarditis Registry

Ischemia | Chest Pain | Myocarditis

United States
Janssen Scientific Affairs, LLC
Bayer; Duke Clinical Research Institute

Completed

Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF)

Atrial Fibrillation

United States, Puerto Rico
Medstar Health Research Institute
Sanofi; Bayer; American Diabetes Association

Completed

The Synergy to Control Emergency Department Hyperglycemia Program for Type 2 Diabetes (STEP-DM)

Diabetes Mellitus, Type 2 | Medication Adherence | HYPERGLYCEMIA

United States
Baker Heart and Diabetes Institute
The Alfred; Monash Medical Centre; Servier Laboratories (Australia) Pty Ltd

Unknown

Cardiovascular Effects of Agomelatine and Escitalopram in Patients With Major Depressive Disorder (MDD)

Major Depressive Disorder (MDD)

Australia
Carelon Research
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Single Ventricle Reconstruction Extension Study (SVR II) - Pediatric Heart Network (SVRII)

Heart Defects
Ottawa Heart Institute Research Corporation
Bristol-Myers Squibb; Sanofi

Completed

Trial of Clopidogrel After Surgery for Coronary Artery Disease (CASCADE Trial) (CASCADE)

Atherosclerosis

Canada
Mt. Sinai Medical Center, Miami
Florida Heart Research Institute

Completed

Contrast Nephropathy and Nitrates (CoNaN)

Contrast Induced Nephropathy

United States
Medstar Health Research Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Dobutamine Echocardiography In Patients With Ischemic Heart Failure Evaluated for Revascularization (DECIPHER)

Heart Diseases | Cardiovascular Diseases | Heart Failure | Coronary Disease | Heart Failure, Congestive
Brandon Hathorn
Baylor Heart and Vascular Institute Cardiovascular Research Review Committee

Completed

Assessment of Strength Outcomes After Use of the PrimusRS for Specificity of Training in a Cardiac Rehabilitation Setting

Coronary Artery Disease | Valve Disease, Heart
Ottawa Heart Institute Research Corporation
Roche Diagnostics; Genome Canada

Active, not recruiting

Biomarkers to Classify Heart Failure

Heart Failure

Canada
Duke University
American Heart Association; Duke Clinical Research Institute

Completed

Mobile Health Behavioral Intervention in Patients With Heart Failure and Diabetes Mellitus (TARGET-HFDM)

Heart Failure | Diabetes Mellitus

United States
Ottawa Heart Institute Research Corporation
Ontario HIV Treatment Network

Completed

The Effects of Statin Therapy on Coronary Flow Reserve and Inflammatory Markers in HIV-Positive Patients

Human Immunodeficiency Virus (HIV) | Cardiovascular Disease (CVD)

Canada
Mario Negri Institute for Pharmacological Research
Heart Care Foundation

Completed

CYCLosporinE A in Reperfused Acute Myocardial Infarction (CYCLE)

Acute Myocardial Infarction

Italy
H. Lee Moffitt Cancer Center and Research Institute
Bayer

Completed

Assess Gamma H2AX Positivity in Circulating Prostate Cancer Cells Before and After Radium 223

Prostate Cancer | Prostate Adenocarcinoma

United States
Janssen Scientific Affairs, LLC
Bayer; Duke Clinical Research Institute

Completed

Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II (ORBIT-AF II) (ORBIT-AF II)

Atrial Fibrillation

United States, Puerto Rico, Virgin Islands (U.S.)
Baker Heart and Diabetes Institute
The Alfred; Peter MacCallum Cancer Centre, Australia; Menzies Institute for Medical... and other collaborators

Not yet recruiting

Risk-guided Disease managEment Plan to prevEnt CAD in Patients Treated With Previous Cancer (REDEEM-CAD)

Coronary Artery Disease
Nova Scotia Health Authority
Canadian Institutes of Health Research (CIHR); Abbott; Ottawa Heart Institute...

Recruiting

Reversal of Atrial Substrate to Prevent Atrial (RASTA AF)

Atrial Fibrillation

Canada
Population Health Research Institute
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Recruiting

Prospective Urban Rural Epidemiology Study (PURE)

Cardiovascular Diseases | Lung Diseases | Cancer | Risk Factor, Cardiovascular | Health Behavior | Injuries | Environmental Exposure | Renal Disease | Communicable Disease

India, Saudi Arabia, Iran, Islamic Republic of, Peru, Pakistan, Argentina, Bangladesh, Brazil, Canada, Chile, China, Colombia, Kazakhstan, Kyrgyzstan, Malaysia, Palestinian Territory, occupied, Philippines, Poland, Russian Federation and more
Kansas City Heart Rhythm Research Foundation
Kansas City Heart Rhythm Institute, Overland Park, KS

Recruiting

Efficacy Rate of Unipolar Polarity Switch for Lesion Assessment in Pulmonary Vein Isolation

Atrial Fibrillation

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI); Heart Failure Clinical Research...

Terminated

Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart Failure (SMMART-HF)

Heart Failure | Mitral Valve Insufficiency

United States, Canada
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Completed

Survey of Attitudes and Factors Associated With CPR in an Older Population

Cardiac Arrest

Canada
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Completed

Predicting Bleeding Risk on Anticoagulant Therapy for Venous Thromboembolism

Venous Thromboembolism

United States, Canada, United Kingdom
Ottawa Heart Institute Research Corporation
Bristol-Myers Squibb; Pfizer; Canadian Institutes of Health Research (CIHR); Me... and other collaborators

Active, not recruiting

Sub-Clinical Atrial Fibrillation Biomarker Study (SCAF-b)

Subclinical Atrial Fibrillation

Canada
German Heart Institute
University College, London; Bambino Gesù Hospital and Research Institute

Unknown

Proof of Concept of Model Based Cardiovascular Prediction

Aortic Valve Disease | Aortic Coarctation | Cardiovascular Modeling | Cardiovascular MRI
ResMed
Royal North Shore Hospital; International Diabetes Center at Park Nicollet; Baker...

Completed

GLYCOSA Study:Effect of PAP Treatment on Glycemic Control in Patients With Type 2 Diabetes

Diabetes Mellitus Type 2

United States, Australia, Canada
Children's Hospital Medical Center, Cincinnati
Children's National Research Institute; Uganda Heart Institute

Completed

Rheumatic Heart Disease Community Streptococcal Treatment Program "RESET"

Rheumatic Heart Disease

Uganda
Lawson Health Research Institute
Heart and Stroke Foundation of Canada

Not yet recruiting

Sweet spoT for cArdiac Rhythm monitorinG After sTrokE (STARGATE)

Stroke | Atrial Fibrillation
Pfizer
National Heart, Lung, and Blood Institute (NHLBI); Carelon Research

Recruiting

A Study to Learn About The COVID-19 (Study) Vaccine (Called COMIRNATY) in People That Are Less Than 21 Years Old.

Myocarditis

United States, Canada
Population Health Research Institute
Heart and Stroke Foundation of Canada

Recruiting

Adjunctive, Low-dose tPA in Primary PCI for STEMI (STRIVE)

Myocardial Infarction | Percutaneous Coronary Intervention

Canada
Montreal Heart Institute
National Health and Medical Research Council, Australia

Completed

Identifying Strategies to Alleviate Cardiovascular Stress in Coronary Patients During Heatwaves

Coronary Artery Disease

Canada
Ottawa Hospital Research Institute
Heart and Stroke Foundation of Ontario

Completed

Sympathetic Activity in Patients With End-stage Renal Disease on Peritoneal Dialysis (SAPD)

End-stage Renal Disease (ESRD) | Kidney Disease

Canada
Duke University
Patient-Centered Outcomes Research Institute; American Heart Association

Completed

Patient-centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER)

Stroke | Ischemic Stroke

United States
Ottawa Hospital Research Institute
Heart and Stroke Foundation of Ontario

Completed

Pro-coagulant Markers and Anticoagulant Failure in Cancer Patients at Risk for Recurrence of Venous Thromboembolism (REMARK)

Cancer | Venous Thromboembolism | Pulmonary Embolism | Deep-Vein Thrombosis

Canada
Ottawa Hospital Research Institute
Heart and Stroke Foundation of Ontario

Completed

Atrial Fibrillation Without Hemodynamic Instability in the Intensive Care Unit (AFIB)

Atrial Fibrillation
Ottawa Hospital Research Institute
Heart and Stroke Foundation of Ontario

Completed

Sex Hormones and Blood PCSK9 Levels

Hypercholesterolemia

Canada
University of Minnesota
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health... and other collaborators

Terminated

Simvastatin Therapy for Moderate and Severe COPD (STATCOPE)

Pulmonary Disease, Chronic Obstructive

United States, Canada
Singapore Clinical Research Institute
National Medical Research Council (NMRC), Singapore; Sirtex Medical; Bayer Healthcare...

Completed

Study of SIR-Spheres Plus Sorafenib as 1st Line Treatment for Non-resectable Primary Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma

Singapore, Korea, Republic of, Malaysia, Myanmar
D'Or Institute for Research and Education
Bayer; RPH Central Pharma

Recruiting

A Phase 2 Trial of Darolutamide as a Prostate-Specific Membrane Antigen (PSMA) Expression Enhancer in Patients With Localized Prostate Cancer

Prostate Cancer

Brazil
Lawson Health Research Institute
Heart and Stroke Foundation of Canada

Recruiting

Identifying Therapeutic Hemodialysis Targets Through Cerebrovascular Reactivity; RESPIRACT 2 (RESPIRACT 2)

Chronic Kidney Failure

Canada
University of British Columbia
Medtronic; Ottawa Heart Institute Research Corporation

Active, not recruiting

The Impact of "First-Line" Rhythm Therapy on AF Progression (PROGRESSIVE-AF)

Atrial Fibrillation

Canada
Boca Raton Regional Hospital
AstraZeneca; Ottawa Heart Institute Research Corporation

Completed

Ticagrelor Antiplatelet Therapy to Reduce Graft Events and Thrombosis (TARGET)

Saphenous Vein Graft Disease

United States, Canada
Innovation Research & Training
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Evaluation Study of Web-based Resource for Youth

Healthy | Chronic Disease

United States
Menssana Research, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Breath Test for Early Detection of Lung Cancer

Lung Neoplasms

United States
Ottawa Hospital Research Institute
Heart and Stroke Foundation of Ontario

Completed

A Survey of Factors Associated With the Successful Recognition of Agonal Breathing and Cardiac Arrest.

Cardiac Arrest

Canada

Clinical Trials Sponsored by Baker Heart Research Institute

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