Clinical Trials Sponsored by BioNTech SE

Total 1843 results

Essen Biotech

Not yet recruiting

Sequential CAR-T Cells Targeting CD33/CD123 in Patients With Acute Myelocytic Leukemia AML (BAH244)

Acute Myeloid Leukemia | AML | AML, Adult | AML, Adult Recurrent

China
Essen Biotech

Not yet recruiting

Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease (BAH243)

Sickle Cell Disease | Sickle-Cell Disease With Crisis

China
Essen Biotech

Not yet recruiting

Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE) (BAH242)

Autoimmune Diseases | Systemic Lupus Erythematosus | Systemic Sclerosis | Lupus Nephritis | Microscopic Polyangiitis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Sjogren's Syndrome | Idiopathic Inflammatory Myopathies | Granulomatous Polyangiitis

China
Swalife Biotech

Not yet recruiting

Observe the Effect of Wheatgrass and Tulsi Formulation or Individuals Taken With Other Allopathic Drugs

Smoking | Blood Sugar; High | Blood Pressure, High | Weight, Birth

India
Cousin Biotech

Recruiting

Laparoscopic Inguinal and Femoral heRniA rePaIr Using Pre-shapeD 4DMESH® (4DLap)

Inguinal Hernia | Femoral Hernia

Belgium, Spain, France
Biotech Dental

Recruiting

Performance and Safety Use of the Mono Block Implant "KONTACT MB"

Dental Implant | Dental Restoration | Dentistry | Implant-supported Fixed Prosthesis

France
Meccellis Biotech

Recruiting

Safety and Clinical Performance of a Biological Matrix Used in Abdominal Wall Reconstruction (PMCF_AWR)

Abdominal Hernia | Abdominal Wall Defect | Abdominal Wall Injury

France
J2H Biotech

Completed

Phase 1 Study to Investigate Safety, Tolerability, PK/PD of J2H-1702 in Healthy Females

Non-alcoholic Steatohepatitis

Korea, Republic of
Acticor Biotech

Active, not recruiting

ACTISAVE: ACuTe Ischemic Stroke Study Evaluating Glenzocimab Used as Add-on Therapy Versus placEbo (ACTISAVE)

Acute Ischemic Stroke

United States, Germany
Meccellis Biotech

Completed

Safety and Performance Evaluation of a Biological Matrix Used for Rectal Prolapse Repair by Ventral Rectopexy

Rectal Prolapse

France
Biotech Dental

Completed

Performance and Safety Use of the Nanostructured Titanium Dental Implant "KONTACT N"

Dental Implant | Edentulous Alveolar Ridge | Dental Restoration | Implant-supported Fixed Prosthesis

France
Rottapharm Biotech

Completed

A Study of the EP4 Antagonist CR6086 in Combination With Methotrexate, in DMARD-naïve Patients With Early Rheumatoid Arthritis

Rheumatoid Arthritis, DMARD-naive and Early Disease Patients

Czechia
ElsaLys Biotech

Available

Early Access Program With Inolimomab in Steroid-refractory Acute Graft Versus Host Disease

Steroid Resistant Acute Graft Versus Host Disease

France
Rottapharm Biotech

Completed

Intra-articular PVA Hydrogel in Knee Osteoarthritis

Knee Osteoarthritis

Poland
Vaxon Biotech

Completed

Efficacy Study of Vx001 Vaccine in NSCLC Patients

Non-small Cell Lung Cancer Metastatic

Germany, Greece, Spain, Romania, France, Italy, Czechia, Poland
Vaxon Biotech

Completed

Safety Study of Vx006 Vaccine in Solid Tumor Patients

Solid Tumor

Greece
Cinfa Biotech

Completed

Pharmacokinetic and Pharmacodynamics of B12019 and Neulasta® in Healthy Subjects

Clinical Pharmacology

Germany
Oncolytics Biotech

Withdrawn

Study of Intratumoral REOLYSIN® in Combination With Gemcitabine and Cisplatin as Neoadjuvant Therapy in Muscle-invasive Transitional Cell Carcinoma of the Bladder

Muscle-invasive Transitional Cell Carcinoma of the Bladder
Oncolytics Biotech

Completed

Phase 2 Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin for Non-Small Cell Lung Cancer With KRAS or EGFR Activation

Carcinoma, Non-small Cell Lung

United States
Neovii Biotech

Terminated

Safety and Efficacy Study of the Trifunctional Antibody Ertumaxomab to Treat Patients With Advanced or Metastatic Breast Cancer (IV REXBC 02)

Breast Cancer | Breast Neoplasms

Belgium
Oncolytics Biotech

Completed

Efficacy Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Platinum-Refractory Head and Neck Cancers

Carcinoma, Squamous Cell of the Head and Neck

United States, Canada, Spain, Belgium, United Kingdom, Greece, Germany, Hungary, Poland, Slovenia, France, Italy, Russian Federation
Puleva Biotech

Completed

Safety of Lactobacillus Fermentum in Newborn Infants

Tolerance

Spain
Neovii Biotech

Completed

CASIMAS: Catumaxomab Safety Phase IIIb Study With Intraperitoneal Infusion in Patients With Malignant Ascites Due to Epithelial Cancers (CASIMAS)

Neoplasms | Carcinoma | Cancer | Malignant Ascites

France, Germany, Italy, Spain
Stryker Biotech

Completed

Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee

Osteoarthritis of the Knee

United States
Puleva Biotech

Completed

Effect of a Follow on Formula With Lactobacillus Fermentum on the Incidence of Infections

Incidence of Infectious Diseases
Facet Biotech

Completed

Humanized Anti-IL-2 Receptor Monoclonal Antibody in Moderate-to-severe Ulcerative Colitis

Ulcerative Colitis | Inflammatory Bowel Disease | Gastrointestinal Disease

United States, Canada, Belgium
Dong-A University
AstraZeneca; Biotronik SE & Co. KG

Completed

Comparing Ticagrelor Versus Clopidogrel on Microcirculation (PLEIO)

Acute Coronary Syndrome

Korea, Republic of
Flanders Medical Research Program
Biotronik SE & Co. KG

Completed

AMS INSIGHT 1 Study - Bioabsorbable Metal Stent Investigation in Chronic Limb Ischemia Treatment (AMS-INSIGHT1)

Peripheral Artery Disease

Austria, Belgium, Germany, Netherlands
Biotronik Australia Pty Ltd.
Biotronik SE & Co. KG

Active, not recruiting

BIO|CONCEPT.Amvia Study

Heart Failure | Bradycardia

Australia
Biotronik Australia Pty Ltd.

Completed

BIO|CONCEPT.Renamic Neo Study

Medical Devices

Australia
Saint Vincent's Hospital, Korea
Biotronik SE & Co. KG

Recruiting

Verifying Remote Monitoring Effect on Net Cardiovascular Outcome; RemoteVerify (RêVe) (ReVe)

Congestive Heart Failure | Cardiac Resynchronization Therapy | Defibrillators

Korea, Republic of
Saint Vincent's Hospital, Korea
Biotronik SE & Co. KG

Completed

Remote Care for CIED Patients in Korea

Arrhythmias, Cardiac

Korea, Republic of
Spanish Society of Cardiology
Biotronik SE & Co. KG

Unknown

Closed Loop Stimulation for Neuromediated Syncope (SPAIN Study) (SPAIN)

Syncope, Vasovagal

Spain
Virogin Biotech Canada Ltd

Recruiting

Phase I Study VG2025 as a Single Agent and in Combination Therapy With Nivolumab in Subjects With Advanced Malignant Solid Tumors

Solid Tumor

United States
Virogin Biotech Canada Ltd

Recruiting

An Open-Label, Multiple-Center, Phase IIa/IIb Clinical Trial to Evaluate the Efficacy, Safety and Tolerability of VG161 as Monotherapy and in Combination With Nivolumab for Treatment of Patients With Hepatocellular Carcinoma or Intrahepatic Cholangiocarcinoma

Hepatocellular Carcinoma | Intrahepatic Cholangiocarcinoma

United States
Centre Hospitalier Universitaire de Besancon
Biotronik SE & Co. KG

Recruiting

Post Intensive Care Unit Atrial Fibrillation (PIAF)

Critical Illness | Atrial Fibrillation

France
Sanofi
BioNTech RNA Pharmaceuticals GmbH

Terminated

A First-in-Human Dose Escalation and Expansion Study to Evaluate Intratumoral Administration of SAR441000 as Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Metastatic Neoplasm

France, Spain, United States, Belgium, Germany, Netherlands
Ortho Biotech, Inc.

Completed

The Effect of PROCRIT (Epoetin Alfa) on Postoperative Vigor and Handgrip Strength (VIGOR Study)

Anemia
Acepodia Biotech, Inc.

Not yet recruiting

ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)

Metastatic Solid Tumor | Locally Advanced Solid Tumor

United States
Canwell Biotech Limited

Not yet recruiting

CAN1012 Combined With PD-1 in Patients With Solid Tumors

Advanced Solid Tumor

China
Shanghai Henlius Biotech

Not yet recruiting

A Randomized, Single Intravenous Dose, Parallel Phase I Clinical Study to Compare the Pharmacokinetic Characteristics, Safety, and Immunogenicity of HLX05 Vs. Erbitux® (Cetuximab) in Healthy Adult Male Chinese Subjects

EGFR Overexpression
Marinomed Biotech AG

Recruiting

Lubricating Effectiveness of Carragelose Eye Drops in Patients Affected by Mild to Moderate Dry Eye

Dry Eye Syndromes

Spain
Krystal Biotech, Inc.

Recruiting

A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

Metastatic Renal Cell Carcinoma | Metastatic Colorectal Cancer | Lung Cancer Metastatic | Lung Cancer, Non-small Cell | Advanced Cancer | Solid Tumor, Adult | Metastatic Osteosarcoma | Metastatic Sarcoma | Metastatic Hepatocellular Carcinoma | Lung Cancer, Small Cell

United States
CEN Biotech
MYEXPRESION

Recruiting

Performance of PEAR 2.0 Software in Prescribing Biotherapy in Patients With Rheumatoid Arthritis

Polyarthritis; Rheumatoid

France
HRYZ Biotech Co.

Recruiting

HRYZ-T101 TCR-T Cell for HPV-18 Positive Advanced Solid Tumor

Cervical Cancer | Head and Neck Squamous Cell Carcinoma | Oropharyngeal Cancer | Anal Carcinoma | Vagina Tumor | Carcinoma of Penis | Carcinoma of Vulva

China
Carina Biotech Limited

Recruiting

A Study of CNA3103 (LGR5-targeted, Autologous CAR-T Cells) Administered to Subjects With Metastatic Colorectal Cancer

Colorectal Cancer Metastatic

Australia
Shanghai Henlius Biotech

Recruiting

A Phase Ib/II Clinical Trial to Evaluate the Safety and Efficacy of HLX208+HLX10 in NSCLC With BRAF V600E Mutation

Non Small Cell Lung Cancer

China
Shanghai Henlius Biotech

Recruiting

Phase II Clinical Study to Compare the Efficacy and Safety of HLX07 + Serplulimab +Chemotherapy Versus Placebo + Serplulimab + Chemotherapy in First-Line Treatment of Patients With Recurrent or Metastatic NPC

Nasopharyngeal Carcinoma by AJCC V8 Stage

China
Krystal Biotech, Inc.

Recruiting

A Study Assessing KB407 for the Treatment of Cystic Fibrosis

Cystic Fibrosis

United States
Moleculin Biotech, Inc.

Recruiting

Study of Liposomal Annamycin in Combination With Cytarabine for the Treatment of Subjects With Acute Myeloid Leukemia (AML)

Leukemia, Myeloid, Acute

Italy, Poland

Clinical Trials Sponsored by BioNTech SE

Sponsors and Collaborators

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CROs in Zambia

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