Clinical Trials Sponsored by Guy's and St Thomas's NHS Foundation Trust

Total 437 results

Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust; Manchester Metropolitan University

Completed

Percutaneous Mitral Valve Intervention: Predicting Improvements in Left Ventricular Performance (PMVI-PiP)

Mitral Regurgitation | Mitral Valve Insufficiency

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
University College, London; The Whittington Hospital NHS Trust

Completed

Intermittent Versus Continuous Feeding in ICU Patients

Intensive Care (ICU) Myopathy

United Kingdom
St George's, University of London
King's College Hospital NHS Trust; Guy's and St Thomas' NHS Foundation Trust

Completed

Exercise Training in Hypertrophic Cardiomyopathy: (SAFE-HCM) (SAFE-HCM)

Hypertrophic Cardiomyopathy

United Kingdom
University College, London
Guy's and St Thomas' NHS Foundation Trust; The Whittington Hospital NHS Trust

Unknown

MACS Study - Microparticles and Coagulation in Sickle Cell Disease (MACS)

Sickle Cell Disease

United Kingdom
King's College London
Co-sponsor: Guy's and St Thomas' NHS Foundation Trust

Completed

Protein and Skeletal Muscle in Older Twins: Role of the Gut Microbiome (PROMOTe)

Frailty | Sarcopenia | Age-Related Sarcopenia

United Kingdom
King's College London
King's College Hospital NHS Trust; Guy's and St Thomas' NHS Foundation Trust; Chelsea and Westminster NHS Foundation Trust

Unknown

OPEN Feasibility Study

HIV Neuropathy

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; Uppsala University

Active, not recruiting

Prostate Cancer Active Surveillance Trigger Trial (PCASTT-UK): Comparing Current Practice for Men With Prostate Cancer on Active Surveillance (AS) to an AS Protocol With Standardised Triggers for Transitioning to Curative Treatment

Prostate Cancer

United Kingdom
King's College London
Diabetes UK; Guy's and St Thomas' Foundation NHS Trust

Completed

A Psychosocial Education Programme for Young People With Type 1 Diabetes - the Youth Empowerment Skills (YES) (YES)

Diabetes Mellitus, Type 1

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
University of Cambridge; Pneumacare Ltd

Completed

Structured Light Plethysmography in Obstructive Airways Disease

Pediatric Respiratory Diseases

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
University College London Hospitals; Guy's and St Thomas' NHS Foundation Trust

Recruiting

Connecting Breath and Mind for CYP With Long COVID

Anxiety | Post-COVID-19 Syndrome | Breathlessness

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; Sir Halley Stewart Trust

Completed

Thinking Outside the Box

Medication Adherence | Medication Compliance | Attitude | Caregivers

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Harvard Medical School (HMS and HSDM)

Recruiting

Study of the Treatment and Outcomes in Critically Ill Patients With COVID-19 and High Risk of Acute Kidney Injury

Critical Illness | Acute Kidney Injury | COVID

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Oxford University Hospitals NHS Trust; NHS Greater Glasgow and Clyde; Northumbria... and other collaborators

Recruiting

Assess the Clinical Effectiveness in AI Prioritising CT Heads (ACCEPT)

Stroke, Ischemic | Skull Fractures | Trauma, Brain | Encephalomalacia | Mass Lesion | Hemorrhage, Intracranial | Midline Deviation

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; The Dunhill Medical Trust

Unknown

Motivating Structured Walking Activity in Intermittent Claudication (MOSAIC)

Peripheral Arterial Disease | Intermittent Claudication | Peripheral Vascular Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust; Royal Brompton & Harefield NHS Foundation... and other collaborators

Not yet recruiting

Haemodynamics of Mitral Regurgitation Reduction (STRESS-MR)

Mitral Regurgitation
King's College London
Guy's and St Thomas' NHS Foundation Trust; Brighton and Sussex University Hospitals...

Recruiting

A Study to Measure the Expression of the HER2-HER3 Dimer in Tumour and Blood (Exosomes) Samples From Patients With HER2 Positive Breast Cancer Receiving HER2 Targeted Therapies (HERdi PREDICT)

HER2-positive Breast Cancer

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; British Heart Foundation

Recruiting

Atrial CMR in Patients With CVA of Unknown Source and no Known AF (CARM-AF)

Atrial Fibrillation | Stroke, Ischemic

United Kingdom
Tom Jackson
Royal Brompton & Harefield NHS Foundation Trust; CardioInsight Technologies...

Completed

Predicting Response to CRT Using Body Surface ECG Mapping

Heart Failure

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; Royal Brompton & Harefield...

Completed

Domiciliary Transcutaneous Electrical Stimulation in Obstructive Sleep Apnoea (TESLA-home)

Obstructive Sleep Apnea

United Kingdom
King's College London
Guy's and St Thomas' NHS Foundation Trust; Action Medical Research

Recruiting

Developing Advanced Neuroimaging for Clinical Evaluation of Autoimmune Encephalitis (DANCE-AE)

Autoimmune Encephalitis | Anti-N-Methyl-D-Aspartate Receptor Encephalitis

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; Imperial College London

Not yet recruiting

Comparing the Effectiveness of Phacoemulsification + ECP Laser and Phacoemulsification Alone for Glaucoma Patients (CONCEPT)

Cataract | Glaucoma Open-Angle Primary
Guy's and St Thomas' NHS Foundation Trust
King's College London; Massachusetts General Hospital

Recruiting

Personalised Responses to Dietary Composition Trial (PREDICT)

Heart Diseases | Healthy | Obesity | Diabetes | Diet Modification | Microbial Colonization | Diet Habit | Metabolism

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
University of Nottingham; University of Warwick

Completed

Personalised Simulation Technologies for Optimising Treatment in the Intensive Care Unit (PSTOTICU)

Respiratory Insufficiency | Respiratory Distress Syndrome, Adult

United Kingdom
King's College London
Cancer Research UK; Guy's and St Thomas' NHS Foundation Trust

Unknown

Assay Development for Cancer Biomarkers

Tumors

United Kingdom
Lightpoint Medical Limited
King's College London; Guy's and St Thomas' NHS Foundation Trust

Completed

LightPathTM Imaging System for Ex-vivo Assessment of Margin and Lymph Node Status in Breast Cancer Surgical Specimens

Breast Cancer

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; University College, London

Recruiting

Cerclage After Full Dilatation Caesarean Section (CRAFT)

Preterm Birth | Preterm Premature Rupture of Membrane | Preterm Spontaneous Labor With Preterm Delivery

United Kingdom
Lightpoint Medical Limited
King's College London; Guy's and St Thomas' NHS Foundation Trust

Unknown

The Breast Surgery EnLight and LightPath Imaging System Study

Breast Neoplasms

United Kingdom
Brighton & Sussex Medical School
Guy's and St Thomas' NHS Foundation Trust; Brighton and Sussex University Hospitals...

Completed

Adherence to Self-care Regimens for Young People With Food Allergy

Food Allergy

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
The Leeds Teaching Hospitals NHS Trust; Versus Arthritis; Serac Healthcare

Not yet recruiting

Scintigraphy for Prediction In Rheumatoid Intentional Therapy Tapering (SPIRITT)

Rheumatoid Arthritis
University of Roma La Sapienza
King's College Hospital NHS Trust; Guy's and St Thomas' NHS Foundation Trust

Completed

A Feasibility Clinical Trial to Evaluate High Frequency Spinal Cord Stimulation for the Treatment of Patients With Chronic Migraine (rCM HF-SCS)

Refractory Chronic Migraine

Italy
King's College London
Guy's and St Thomas' NHS Foundation Trust; UK Research and Innovation

Recruiting

Role of the Oral Microbiome & Mucosal Immunity in COVID-19 Disease (MIMSA)

COVID-19 | Periodontal Diseases | Microbial Colonization | Oral Disease | Mucosal Infection | Innate Inflammatory Response

United Kingdom
King's College London
Guy's and St Thomas' NHS Foundation Trust; Integra LifeSciences Corporation

Unknown

Evaluating Outcomes of Immediate Breast Reconstruction (POBRAD-M) (POBRAD-M)

Breast Neoplasms | Breast Diseases

United Kingdom
King's College London
University College London Hospitals; Guy's and St Thomas' NHS Foundation Trust and other collaborators

Unknown

Advances in Group-based Falls Rehabilitation

Accidental Falls
Norfolk and Norwich University Hospitals NHS Foundation...
Guy's and St Thomas' NHS Foundation Trust; University Hospitals, Leicester; University... and other collaborators

Recruiting

The CAVA Multicentre Dizziness Trial (CAVA 2)

Vestibular Migraine | Benign Paroxysmal Positional Vertigo (BPPV) | Ménière's Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; City, University of London

Completed

Lubricating Eye Drops After Routine Cataract Surgery

Cataract | Dry Eye

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
National Institute for Health Research, United Kingdom

Active, not recruiting

Pneumococcal Vaccination to Accelerate Immune Recovery in Sepsis Survivors (VACIRiSS)

Sepsis

United Kingdom
King's College London
University College London Hospitals; Guy's and St Thomas' NHS Foundation Trust

Unknown

Advances in Vestibular Rehabilitation

Vestibular

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; City, University of London

Unknown

Posterior Capsular Opacification and Glistenings in Hydrophobic and Hydrophilic Intraocular Lenses

Cataract | Intraocular Lens Opacification
Guy's and St Thomas' NHS Foundation Trust
King's College London; City, University of London

Completed

A Study Comparing Two Monofocal, Aspheric, Hydrophobic Acrylic Intraocular Lenses: the Alcon CLAREON® and the Abbott Medical Optics PCB00

Patient Satisfaction | Cataract Extraction | Cataract Surgery | Phacoemulsification | Intraocular Lens Implant | Patient Related Outcome Measures | Glistenings | Hydrophobic Acrylic | Light Scatter

United Kingdom
South London and Maudsley NHS Foundation Trust
Special Trustees for St Thomas' and Guy's Hospitals

Unknown

Cognitive Behavioural Therapy in Dissociative Seizures

Dissociative Seizures

United Kingdom
King's College London
Guy's and St Thomas' NHS Foundation Trust; MND Association; Marie Curie Charity

Recruiting

Virtual Peer-to-peer Support Programme for Carers of MND

Motor Neuron Disease | Amyotrophic Lateral Sclerosis

United Kingdom
NanoMab Technology (UK) Limited
King's College London; Guy's and St Thomas' NHS Foundation Trust

Recruiting

PD-L1 Expression in Lung Cancer (PELICAN)

Non-Small Cell Lung Cancer

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

CT Guided WiSE-CRT

Heart Failure

United Kingdom
King's College Hospital NHS Trust
London School of Hygiene and Tropical Medicine; Guy's and St Thomas' NHS Foundation...

Unknown

Comparison Between Propofol and Inhalational Anaesthetic Agents on Cardiovascular Outcomes Following Cardiac Surgery (COPIA)

Cardiovascular Diseases | Coronary Heart Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; City, University of London

Not yet recruiting

Comparison of Aspheric Toric Intraocular Lenses for Micro-monovision

Cataract | Presbyopia | Astigmatism

United Kingdom
Imperial College London
University College London Hospitals; Guy's and St Thomas' NHS Foundation Trust

Completed

Neuroprotective Effects of Hypothermia Combined With Inhaled Xenon Following Perinatal Asphyxia (TOBYXe)

Hypoxic Ischaemic Encephalopathy

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; City, University of London

Unknown

Use of Prophylactic Lubricating Drops After Cataract Surgery

Dry Eye | Patient Satisfaction | Cataract Surgery | Patient Related Outcome Measures

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; City, University of London

Unknown

Toric Intraocular Lenses for Cataract Patients in the NHS

Cataract | Astigmatism | Cornea
Guy's and St Thomas' NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

The Feasibility of Measuring Energy Expenditure During Physical Rehabilitation In Critically Ill Patients (ENERGY-ICU)

Intensive Care

United Kingdom
King's College Hospital NHS Trust
King's College London; Cardiff University; Guy's and St Thomas' NHS Foundation... and other collaborators

Recruiting

Beta-blockers for Oesophageal Varices (BOPPP)

Cirrhoses, Liver | Oesophageal Varices

United Kingdom

Clinical Trials Sponsored by Guy's and St Thomas's NHS Foundation Trust

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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CROs in Germany

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