Clinical Trials Sponsored by Ligand+Pharmaceuticals

Total 19894 results

Liegang Liu

Completed

Associations of Plasma Vanadium Concentrations With Gestational Diabetes Mellitus

Gestational Diabetes
Liegang Liu

Completed

Plasma Transthyretin Levels and Risk of Type 2 Diabetes Mellitus and Impaired Glucose Regulation

Type 2 Diabetes | Impaired Glucose Regulation
Claudio Gobbi
Merck AG Switzerland

Active, not recruiting

Safety and Efficacy of Cladribine Therapy After Anti CD20 Therapy

Multiple Sclerosis

Switzerland
Liegang Liu

Completed

Association of β-amyloid 40 and 42 With Prediabetes

PreDiabetes
Liegang Liu

Completed

Association Between TMAO and Diabetes

Type2 Diabetes
ISA Pharmaceuticals
Regeneron Pharmaceuticals

Active, not recruiting

A Randomized Phase 2 Study of Cemiplimab ± ISA101b in HPV16-Positive OPC

Squamous Cell Carcinoma of the Oropharynx | HPV16 Positive

Netherlands, United States, United Kingdom, France, Belgium, Czechia, Spain, Italy, Germany, Brazil, Hungary, Mexico, Poland
Portola Pharmaceuticals

Completed

Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 2 of 4)

Healthy Volunteers
Portola Pharmaceuticals

Completed

Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 4 of 4)

Healthy Volunteers
Portola Pharmaceuticals

Completed

The Effect o f Hepatic Impairment on the Pharmacokinetics and Pharmacodynamics of Betrixiban, an Oral FXa Antagonist

Hepatic Impairment

United States
Portola Pharmaceuticals

Withdrawn

BRAVO - Betrixaban Registry Using Real Time Observations in Acute Medical Illness to Assess Venous Thrombosis and Bleeding Outcomes

Venous Thromboses

United States
Jazz Pharmaceuticals
GW Pharmaceuticals

Completed

An Open-label Extension Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)

Seizures | Tuberous Sclerosis Complex

United States
Solvay Pharmaceuticals
Unimed Pharmaceuticals

Completed

Observation Study of T-Gel (1%) in Treatment of Adolescent Boys With Hypogonadism

Primary or Secondary Hypogonadism | Constitutional Delay in Growth and Puberty (CDGP)

United States
Solvay Pharmaceuticals
Unimed Pharmaceuticals

Completed

Pharmacokinetic Evaluation of Testosterone Gel (1%)

Primary or Secondary Hypogonadism | Constitutional Delay in Growth and Puberty (CDGP)

United States
Portola Pharmaceuticals

Completed

Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 3 of 4)

Healthy Volunteers

United States
Portola Pharmaceuticals

Withdrawn

CELTIC-1: A Phase 2B Study of Cerdulatinib in Patients With Relapsed/Refractory Peripheral T-Cell Lymphoma (PTCL)

AITL | Peripheral T-Cell Lymphoma (PTCL NOS) | Nodal Lymphomas of T Follicular Helper (TFH) | Follicular T-cell Lymphoma (FTCL) | ALCL | HSTCL | EATL I,II | MEITL, EATL Type II | Nasal Lymphoma
Portola Pharmaceuticals

Completed

A Study in Older Subject to Evaluate the Safety and Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Rivaroxaban

Bleeding

United States
Regeneron Pharmaceuticals
Alnylam Pharmaceuticals

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Pozelimab in Combination With Cemdisiran in Healthy Adult Volunteers

Healthy

Belgium
Ferring Pharmaceuticals
Xanodyne Pharmaceuticals

Completed

A Study of Tranexamic Acid (XP12B) in Women With Heavy Menstrual Bleeding

Menorrhagia

United States
Ping Liang

Recruiting

Clinical Decision Biological Biomarker and Prognosis Prediction of Hepatocellular Carcinoma by Deep Learning

Hepatocellular Carcinoma | Surgery | Ablation | Prognosis | Contrast-enhanced Ultrasound

China
XinLing Liang

Recruiting

Prognosis of Acute Kidney Injury:China Collaborative Study on AKI（CCS-AKI）Study

Acute Kidney Injury

China
Jing Liang

Unknown

Safety, Efficacy and Operability of Using the New Tissue Containment System During Laprascopic Hysterectomy

Gynecologic Surgery
ISA Pharmaceuticals
Regeneron Pharmaceuticals

Active, not recruiting

A Phase II Study of Cemiplimab and ISA101b in Patients With Recurrent/Metastatic HPV16 Positive OPC

Squamous Cell Carcinoma of the Oropharynx

United States, Israel, Belgium, Germany, Spain, United Kingdom, Italy, France, Czechia
Portola Pharmaceuticals

Completed

A Healthy Volunteer Pharmacokinetics (PK)/Pharmacodynamics (PD), Safety and Tolerability Study of Andexanet in Healthy Japanese and Caucasian Subjects

Bleeding

United States
Jazz Pharmaceuticals
GW Pharmaceuticals

Terminated

A Long-term Safety Study of Cannabidiol Oral Solution (GWP42003-P, CBD-OS) in Patients With Rett Syndrome

Rett Syndrome | RTT

United States, Canada, Italy, Spain, United Kingdom, Australia
Alexion Pharmaceuticals
Portola Pharmaceuticals

Completed

Phase 1/2a Dose Escalation Study in Participants With CLL, SLL, or NHL

Follicular Lymphoma (FL/Indolent NHL) | Aggressive NHL (a NHL) | Chronic Lymphocytic Leukemia (CLL) / Small Lymphocytic Lymphoma (SLL) | T-cell Lymphoma (PTCL and CTCL) | B-cell Non Hodgkin Lymphoma (NHL)

United States
Schön Klinik Berchtesgadener Land

Recruiting

CO2-Patterns During Hyperoxia and Physical Exercise in COPD

COPD

Germany
Schön Klinik Berchtesgadener Land

Completed

Effect of Inpatient Pulmonary Rehabilitation on Frailty in Candidates for Lung-Transplantation

COPD | ILD | Advanced Lung Disease

Germany
Schön Klinik Berchtesgadener Land

Completed

Benefits of Pulmonary Rehabilitation in Patients With Severe Lymphangioleiomyomatosis (LAM)

Lymphangioleiomyomatosis | Pulmonary Rehabilitation | LAM

Germany
Schön Klinik Berchtesgadener Land

Completed

Effects of Whole-Body Vibration Training Versus Balance Training in Patients With Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

Germany
Schön Klinik Berchtesgadener Land

Unknown

Effects of Different Exercise Training Modalities in Alpha-1 Antitrypsin Deficiency Patients

Chronic Obstructive Pulmonary Disease | Alpha 1-Antitrypsin Deficiency

Germany
Schön Klinik Berchtesgadener Land

Completed

Effects of Supplemental Oxygen Delivered by a Portable Oxygen Concentrator Compared to a Liquid Oxygen Device in COPD

Chronic Obstructive Pulmonary Disease

Germany
Schön Klinik Berchtesgadener Land

Completed

Continuous Versus Interval Walking Training in Patients With COPD - a Pilot Study

Chronic Obstructive Airway Disease

Germany
Schön Klinik Berchtesgadener Land

Completed

Cardiorespiratory Response During Whole Body Vibration Training in Patients With Chronic Lung Disease

Chronic Obstructive Lung Disease (n=10) | Interstitial Lung Disease (n=10)

Germany
Schön Klinik Berchtesgadener Land

Completed

Effects of a Whole Body Vibration Training in Patients After Lung Transplantation

Patients Following Lung Transplantation (Single and Double)

Germany
NovaBay Pharmaceuticals, Inc.
Novum Pharmaceutical Research Services; International Dermatology Research,...

Completed

Safety and Efficacy of Topical NVC-422 Gel in Impetigo

Impetigo

Dominican Republic
PETHEMA Foundation
Millennium Pharmaceuticals, Inc.; Johnson & Johnson Pharmaceutical Research...

Completed

Velcade-Melphalan-Prednisone in Older Untreated Multiple Myeloma Patients.

Multiple Myeloma

Spain
Nanjing Legend Biotech Co.
Janssen Research & Development, LLC

Recruiting

A Study of LCAR-B38M CAR-T Cells, a Chimeric Antigen Receptor T-cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Chinese Participants With Relapsed or Refractory Multiple Myeloma (CARTIFAN-1)

Multiple Myeloma

China
Liegang Liu

Completed

Associations of Plasma Fatty Acid Patterns With Gestational Diabetes Mellitus

Gestational Diabetes
Douglas Pharmaceuticals America Ltd
Novum Pharmaceutical Research Services; ACM Global Laboratories

Completed

A Therapeutic Equivalence Study of Ketoconazole Cream 2%

Tinea Pedis

Belize, United States
Schön Klinik Berchtesgadener Land

Completed

Sleep Characteristics in Post-COVID-19 Patients

Post-COVID-19

Germany
Schön Klinik Berchtesgadener Land

Completed

Automatic Oxygen Titration in Patients After SARS-CoV-2 Infection

Post-COVID19

Germany
Schön Klinik Berchtesgadener Land

Unknown

Coping Strategies Within Pulmonary Rehabilitation in Patients With IPF and COPD

Chronic Obstructive Pulmonary Disease | Idiopathic Pulmonary Fibrosis

Germany
Schön Klinik Berchtesgadener Land

Completed

Effects of an Auto-Regulating Oxygen System Compared to Constant-Flow Oxygen During Walking in Hypoxemic COPD Patients

COPD

Germany
Schön Klinik Berchtesgadener Land

Unknown

The Effect of Reflective Breathing Therapy Compared With Conventional Breathing Therapy in Patients With Chronic Obstructive Pulmonary Disease (COPD) III-IV; part2

Chronic Obstructive Pulmonary Disease

Germany
Schön Klinik Berchtesgadener Land

Completed

Effects of Vibration Training on Exercise Capacity in COPD-patients

Chronic Obstructive Pulmonary Disease

Germany
Schön Klinik Berchtesgadener Land

Unknown

Effects of Nocturnal Non-invasive Ventilation on Energy Expenditure in Patients With Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | Pulmonary Rehabilitation | Energy Expenditure | Non-invasive Ventilation

Germany
Mu Dong Liang

Not yet recruiting

The Effect and Mechanism of Computerized Cognition Training on the Incidence of Postoperative Cognitive Dysfunction After Cardiac Surgery

Postoperative Cognitive Dysfunction(POCD)
Wrightington, Wigan and Leigh NHS Foundation Trust

Completed

Kinematics of Silastic Joint Replacements in the Hand

Inflammatory Arthritis | Degenerative Arthritis

United Kingdom
LIANA FATTORI ABATI

Completed

Three- Dimensional Evaluation of Accelerated Tooth Movement

Malocclusion

Brazil
Nai Liang Li

Completed

Quality Study of Anesthetic Technique on Breast Cancer Surgery (PQSAT)

Postoperative Pain | Satisfaction | Quality of Recovery

Taiwan

Clinical Trials Sponsored by Ligand+Pharmaceuticals

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Finland

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Rare Diseases

Drug Interventions

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