Continuous Versus Interval Walking Training in Patients With COPD - a Pilot Study

February 23, 2016 updated by: Klaus Kenn, Schön Klinik Berchtesgadener Land

Continuous Versus Interval Walking Training in Patients With Severe Chronic Obstructive Pulmonary Disease - a Pilot Study

This study will investigate the effects of interval walking training versus continuous walking training in patients with chronic obstructive pulmonary disease. Patients will be recruited during a 3-week inpatient pulmonary rehabilitation program and will be randomized to one of the two intervention groups. All walking training sessions will be performed on the same treadmill. Walking intensity in the continuous walking group will be 60 percent of the average speed of the 6-minute walking test. Patients in the interval training group will perform high intensity intervals at 120% of the 6-minute walking test speed for 60 seconds alternating with 60 seconds of rest. The total exercise duration will be progressively increased from 10 to 32 minutes.

Study Overview

Status

Completed

Study Type

Interventional

Enrollment (Actual)

20

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

      • Schönau am Königssee, Germany, 83471
        • Schön Klinik Berchtesgadener Land

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • ADULT
  • OLDER_ADULT
  • CHILD

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • COPD stage III or IV according to the Global Initiative for chronic obstructive lung disease [GOLD]
  • stationary patient in the Schön Klinik Berchtesgadener Land

Exclusion Criteria:

  • acute, severe exacerbation of COPD
  • failure to comply with study process

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: TREATMENT
  • Allocation: RANDOMIZED
  • Interventional Model: PARALLEL
  • Masking: SINGLE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
ACTIVE_COMPARATOR: Continuous walking training
n=10 patients with COPD Walking intensity 60 percent of 6-minute walking test speed
ACTIVE_COMPARATOR: Interval walking training
n=10 patients with COPD Walking intensity 120 percent of 6-minute walking test speed for 1 minute alternating with 1 minute of rest

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
perceived exertion for dyspnea during walking training
Time Frame: day 1 to 21
measured via modified Borg scale (0 to 10)
day 1 to 21

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
heart rate during walking training
Time Frame: day 1 to 21
day 1 to 21
perceived exertion for leg fatigue (Borg-scale)
Time Frame: during three weeks of rehabilitation
during three weeks of rehabilitation
Oxygen saturation during walking training
Time Frame: day 1 to 21
measured via pulse oximeter
day 1 to 21
fat free mass in kilogram
Time Frame: day 1 to 21
measured via Bioimpedance Analysis
day 1 to 21
forced expiratory volume in 1 second (FEV1) in liter
Time Frame: day 1 to 21
measured by spirometry
day 1 to 21
Sit-to-stand-test
Time Frame: day 1 to 21
5 repetitions of standing up and sitting down from a chair with crossed arms as quick as possible
day 1 to 21
6-minute walking test
Time Frame: day 1 to 21
the best 6-minute walking test out of two tests on admission and at discharge will be taken
day 1 to 21
36 item short-form health Survey (SF-36)
Time Frame: day 1 to 21
questionnaire for disease unspecific quality of life
day 1 to 21
chronic respiratory questionnaire (CRQ)
Time Frame: day 1 to 21
disease specific quality of life questionnaire
day 1 to 21
hospital anxiety and depression scale (HADS)
Time Frame: day 1 to 21
questionnaire on symptoms of anxiety and depression
day 1 to 21

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

July 1, 2014

Primary Completion (ACTUAL)

November 1, 2015

Study Completion (ACTUAL)

November 1, 2015

Study Registration Dates

First Submitted

July 31, 2014

First Submitted That Met QC Criteria

August 1, 2014

First Posted (ESTIMATE)

August 5, 2014

Study Record Updates

Last Update Posted (ESTIMATE)

February 24, 2016

Last Update Submitted That Met QC Criteria

February 23, 2016

Last Verified

February 1, 2016

More Information

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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