Search clinical trials for: Ixodes ricinus-Contact Phase Inhibitor

Total 81532 results

Fundació Institut Germans Trias i Pujol
Germans Trias i Pujol Hospital; University of Turin, Italy; Instituto de Salud... and other collaborators

Recruiting

Safety and Impact of Dasatinib on Viral Persistence and Inflammation in People With HIV Under Antiretroviral Treatment

HIV Infection Primary

Spain
National Cancer Centre, Singapore
Taiho Pharmaceutical Co., Ltd.

Recruiting

A Phase 2 Study of Osimertinib and S-1 in Treatment Resistant EGFR Mutant NSCLC

NSCLC

Singapore
Nader Sanai
Barrow Neurological Institute; Ivy Brain Tumor Center

Recruiting

Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG

Glioma | Glioblastoma | High Grade Glioma | Glioma, Malignant

United States
Shanghai Pulmonary Hospital, Shanghai, China

Recruiting

Induction Therapy With PD-1 Antibody Combined With Platinum-based Doublet Chemotherapy for Locally-advanced Non-small Cell Lung Cancer

Non-small Cell Lung Cancer | Locally Advanced

China
University Hospital, Antwerp
Roche Pharma AG; Algemeen Ziekenhuis Maria Middelares; Kom Op Tegen Kanker; Vitaz

Recruiting

Integration of the PD-L1 Inhibitor Atezolizumab and WT1/DC Vaccination Into Platinum/Pemetrexed-based First-line Treatment for Epithelioid Malignant Pleural Mesothelioma (Immuno-MESODEC)

Malignant Pleural Mesothelioma

Belgium
1ST Biotherapeutics, Inc.
Merck Sharp & Dohme LLC

Recruiting

A Phase I/II, Open-label Study to Investigate the Safety, Tolerability, PK, and Preliminary Efficacy of FB849

Advanced Solid Tumor

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; Leap Therapeutics,...

Recruiting

Phase 2 Study Evaluating the Efficacy of the Combination of DKN-01 (DKK1 Inhibitor, Leap Therapeutics) and Pembrolizumab in the Treatment of Advanced or Recurrent Endometrial Cancer

Endometrial Cancer

United States
Sun Yat-sen University

Recruiting

TACE-HAIC Plus Atezolizumab and Bevacizumab for Unresectable HCC: a Phase 2 Clinical Trial

Hepatocellular Carcinoma

China
Yonsei University

Not yet recruiting

First-line Trastuzumab, Gemcitabine, Cisplatin and Nivolumab in Advanced HER2- Positive Biliary Tract Cancer: a Multicenter, Open-label, Single-arm Phase Ib/II Trial (HERBOT)

HER2 Positive Advanced/Metastatic/Nonresectable Biliary Tract Cancer

Korea, Republic of
Hefei TG ImmunoPharma Co., Ltd.

Recruiting

A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors

Melanoma | Colorectal Cancer | Ovarian Cancer | Triple Negative Breast Cancer

United States
Sun Yat-sen University
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Not yet recruiting

A Phase Ib/II Clinical Study of Camrelizumab and Apatinib Plus GP in the Treatment of Advanced Biliary Tract Cancer

Metastatic Biliary Tract Cancer | Locally Advanced Biliary Tract Cancer

China
Shandong New Time Pharmaceutical Co., LTD

Not yet recruiting

A Phase II Study of Rulonilimab Combined With Chemotherapy in the First-Line Treatment for Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

NSCLC | Non-small Cell Lung Cancer | PD-1

China
Xuanzhu Biopharmaceutical Co., Ltd.

Not yet recruiting

To Evaluate the Phase I Clinical Study of XZB-0004 in Patients With AML and MDS

AML | MDS

China
Imunon
Break Through Cancer Foundation

Recruiting

Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer (MRD)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

United States
M.D. Anderson Cancer Center
Mirati Therapeutics

Recruiting

Phase I Trial of Adagrasib (MRTX849) in Combination With Cetuximab and Irinotecan in Patients With Colorectal Cancer

Colorectal Cancer | Colon Cancer

United States
Corium, Inc.
Worldwide Clinical Trials; Premier Research Group plc; Almac; Prometrika, LLC

Recruiting

A Safety/Tolerability and PK Study With Azstarys® in Children With ADHD (KP415P02)

Attention Deficit/Hyperactivity Disorder

United States
Trakya University

Recruiting

The Effect of Virtual Reality on Preoperative Anxiety Before Abdominal Surgery

Anxiety

Turkey
Sun Yat-sen University

Not yet recruiting

SBRT Plus Lenvatinib and TACE for Advanced Primary HCC: A Phase 3 Trial (SEARCH) (SEARCH)

Advanced Hepatocellular Carcinoma

China
University Health Network, Toronto

Not yet recruiting

meChANisms and sAfety of SGLT2 Inhibition in peRitoneal dialYsis (CANARY)

End Stage Kidney Disease | Kidney Dysfunction | Peritoneal Dialysis Complication | Sodium-glucose Co-transporter-2 Inhibitors | Residual Kidney Function

Canada
M.D. Anderson Cancer Center
Mereo BioPharma

Recruiting

EON: A Single-arm Phase II Study of Etigilimab (OMP-313M32) in Combination With Checkpoint Inhibition (Nivolumab) in Patients With Platinum-resistant, Recurrent Epithelial Ovarian Cancer

Ovarian Cancer

United States
Palatin Technologies, Inc

Recruiting

A Phase IIb, Multicenter, Open-Label, Prospective Study of Bremelanotide in Diabetic Kidney Disease (BREAKOUT)

Kidney Disease

United States
TJ Biopharma Co., Ltd.

Recruiting

A Phase 3 Clinical Study to Evaluate Lemzoparlimab for Injection in Combination With Azacitidine (AZA) Versus AZA Monotherapy in Treatment-naïve Patients With Higher-risk Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes(MDS)

China
KARE Biosciences
Biomedical Advanced Research and Development Authority; BioLink Life Sciences... and other collaborators

Recruiting

Phase 2/Phase 3 Study To Evaluate The Efficacy And Safety Of Ramatroban Along With The Standard Of Care In Subjects Hospitalized For COVID Pneumonia

COVID-19 Pneumonia | COVID-19 Respiratory Infection

India
M.D. Anderson Cancer Center

Recruiting

Phase II Study of Nivolumab in Combination With Relatlimab in Patients With Active Melanoma Brain Metastases

Melanoma (Skin)

United States
EDDC (Experimental Drug Development Centre), A*STAR...
Parexel

Recruiting

A Study of EBC-129 in Advanced Solid Tumours

Advanced Solid Tumours

United States, Singapore
M.D. Anderson Cancer Center

Recruiting

Phase II Trial of the PARP Inhibitor Niraparib and PD-1 Inhibitor Dostarlimab in Patients With Advanced Cancers With Active Progressing Brain Metastases (STARLET)

Brain Metastases

United States
Laboratoire français de Fractionnement et de Biotechnologies

Recruiting

A Phase 3 Study of the Safety and Efficacy of Coagulation Factor VIIa (Recombinant) for the Prevention of Excessive Bleeding in Patients With Congenital Hemophilia A or B With Inhibitors to Factor VIII or IX Undergoing Elective Major Surgical Procedures SCOPE HIM (SCOPE HIM)

Hemophilia

United States, Thailand, Mexico, Turkey, South Africa, Malaysia
Esperion Therapeutics, Inc.

Recruiting

A Phase 2 Clinical Study in Children With HeFH Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing (CLEAR Path 1)

Hypercholesterolemia

United States, Spain, Denmark, Canada, Netherlands, Germany
University of California, San Francisco
GlaxoSmithKline

Recruiting

Combination Therapy in Cancers With Mutations in DNA Repair Genes

Metastatic Solid Tumor | BRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene Mutation

United States
AstraZeneca

Recruiting

Phase III, Open-label, First-line Study of Dato-DXd in Combination With Durvalumab and Carboplatin for Advanced NSCLC Without Actionable Genomic Alterations (AVANZAR)

NSCLC

China, United States, United Kingdom, Korea, Republic of, Italy, Hungary, Spain, Vietnam, France, Brazil, Canada, Japan, Taiwan, Germany, Austria, Turkey, India, Peru, Poland, Sweden, Bulgaria, Greece, Mexico, Denmark
University of Mississippi Medical Center
Eli Lilly and Company

Recruiting

Empagliflozin in ESKD - A Feasibility Study

Heart Failure | Kidney Failure, Chronic

United States
University of Campinas, Brazil

Recruiting

DApagliflozin Cardiovascular Effects on Patients at End-stage REnal Disease (Dare-Esrd)

End-stage Kidney Disease

Brazil
M.D. Anderson Cancer Center
Daiichi Sankyo

Recruiting

A Phase 1/2, Open-label Study of Valemetostat in Combination With Rituximab and Lenalidomide in Relapsed or Refractory Follicular Lymphoma

Lymphoma

United States
Baptist Health South Florida
BeiGene

Recruiting

Zanubrutinib With Pemetrexed to Treat Relapsed/Refractory Primary and Secondary Central Nervous System (CNS) Lymphomas

Primary Central Nervous System Lymphoma | Relapsed Cancer | Refractory Cancer | Secondary Central Nervous System Lymphoma

United States
Cancer Institute and Hospital, Chinese Academy...

Recruiting

A Phase II Study Evaluating the Efficacy and Safety of Pembrolizumab in Combination With Chemotherapy as Neoadjuvant Therapy for Triple-negative Breast Cancer

Breast Cancer

China
M.D. Anderson Cancer Center
Genentech, Inc.

Recruiting

Phase 2 Trial of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab in Patients With Newly Diagnosed PD-L1 CPS Positive Resectable Stage 3-4 Oral Cavity Squamous Cell Carcinoma (OCSCC).

Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma

United States
Ruijin Hospital
The First Affiliated Hospital of Anhui Medical University; The First Affiliated... and other collaborators

Recruiting

Genotype-guided Treatment in Newly Diagnosed PTCL (THEORY)

Peripheral T Cell Lymphoma

China
M.D. Anderson Cancer Center
Gilead Sciences

Recruiting

A Phase II Study of Neoadjuvant Sacituzumab Govitecan and Pembrolizumab Therapy for Immunochemotherapy-resistant Early-stage Triple-negative Breast Cancer (TNBC)

Breast Cancer

United States
M.D. Anderson Cancer Center
Genentech, Inc.; Seagen Inc.

Recruiting

A Phase II Study of Tucatinib and Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2-positive Metastatic Solid Tumors and Metastases to Brain (TUCATEMEB)

Metastatic Solid Tumor | Brain Metastases

United States
Yale University
Boehringer Ingelheim

Recruiting

Effect of Empagliflozin on Peritoneal and Kidney Function in End Stage Renal Disease (EMPA-PD)

End Stage Renal Disease on Dialysis

United States
Zhejiang Cancer Hospital

Recruiting

A Phase III Trial of Anus-preservation in Low Rectal Adenocarcinoma Based on MMR/MSI Status

Radiation | Toripalimab

China
M.D. Anderson Cancer Center
Tvardi Therapeutics, Inc

Not yet recruiting

Phase I/II Open Label Study Evaluating the Safety and Efficacy of Combining STAT3 Inhibition (TTI-101) With Anti-PD-1 Therapy (Pembrolizumab) in Patients With Recurrent or Metastatic (RM) Head and Neck Squamous Cell Carcinoma (HNSCC)

Head and Neck Squamous Cell Carcinoma
InventisBio Co., Ltd

Recruiting

Phase II Study to Evaluate Efficacy and Safety of D-0120 in Combination With Allopurinol in Subjects With Gout

Gout

United States
AstraZeneca

Not yet recruiting

A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide as Compared With Those Who Initiated Other Non-Glucagon-Like Peptide 1 Receptor Agonists Based Glucose Lowering Drugs (EXCEED)

Pancreatic Cancer
Hill Dermaceuticals, Inc.

Recruiting

Phase III Efficacy and Safety Study of Miconazole Oil for Otomycosis

Otomycosis

United States
Jiangsu vcare pharmaceutical technology co., LTD

Recruiting

Assessment of the Effect of Omeprazole on Vicagrel in Healthy Subjects

Healthy Subjects

China
University of Oxford

Recruiting

A Phase 2 Trial Comparing Antiviral Treatments in Early Symptomatic Influenza (AD ASTRA)

Influenza | Influenza, Human

Thailand
AstraZeneca

Recruiting

First in Human Study of AZD9592 in Solid Tumors (EGRET)

Head and Neck Neoplasms | Colorectal Neoplasms | Advanced Solid Tumours | Carcinoma Non-small Cell Lung

United States, China, Korea, Republic of, Spain, Australia, Japan, Malaysia, Taiwan, Canada, France, Italy
Hospital Universitario Dr. Jose E. Gonzalez
Fernando De la Garza Salazar

Recruiting

Cytochrome P450 Inhibition to Decrease Dosage of Dasatinib for Chronic Myelogenous Leukemia

Chronic Myeloid Leukemia, Chronic Phase

Mexico
M.D. Anderson Cancer Center
Jazz Pharmaceuticals

Recruiting

Phase 1b of Lurbinectedin in Combination With Weekly Paclitaxel and Bevacizumab in Platinum-resistant Ovarian Cancer

Ovarian Cancer

United States

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