Search clinical trials for: Reduced Toxicity

Total 3073 results

Fifth Affiliated Hospital, Sun Yat-Sen University

Recruiting

The Efficacy and Safety of De-escalated Postoperative Radiotherapy in Locally Advanced HNSCC With pCR/MPR

Head and Neck Squamous Cell Carcinoma

China
Impulse Dynamics

Recruiting

Assessment of Combined CCM and ICD Device in HFrEF (INTEGRA-D)

Heart Failure | Arrhythmias, Cardiac | Ventricular Fibrillation | Ventricular Tachycardia | Implantable Defibrillator User | Heart Failure With Reduced Ejection Fraction | Ischemic Cardiomyopathy | Sudden Cardiac Arrest | Non-ischemic Cardiomyopathy | CCM Therapy

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Not yet recruiting

A Big Data Approach to Predict NEOnatal Acute Kidney Injury in Newborns expoSed to nephroTOxic Drugs (NeoAKI STOP) (NeoAKISTOP)

Premature Birth | Acute Kidney Injury | Drug Use | Machine Learning | Newborn Morbidity | Drug Interaction | Drug Toxicity | Drug-Induced Nephropathy

Italy
Bayer
Regeneron Pharmaceuticals

Recruiting

A Study to Learn How Well a Higher Amount of Aflibercept Given as an Injection Into the Eye Works and How Safe it is in People With Reduced Vision Due to Swelling in the Macula, Central Part of the Retina Caused by a Blocked Vein in the Retina (Macula Edema Secondary to Retinal Vein Occlusion) (QUASAR)

Macular Edema Secondary to Retinal Vein Occlusion

Japan, Korea, Republic of, China, Israel, Lithuania, United States, Italy, Spain, Hungary, Portugal, Serbia, Poland, United Kingdom, Thailand, Czechia, Austria, Germany, Turkey, Australia, Bulgaria, Estonia, France, Georgia, Latvia, Mal... and more
Imperial College London

Recruiting

Video Game Hearing Tests for Remote Monitoring of Ototoxicity (VAROT)

Hearing Loss | Aminoglycoside Toxicity | Video Games | Aminoglycoside-Induced Hearing Loss

United Kingdom
Moi University
Amsterdam UMC, location VUmc; Princess Maxima Center for Pediatric Oncology

Recruiting

CHildren Treated With Vincristine: A Trial Regarding Pharmacokinetics, DNA And Toxicity of Targeted Therapy In Pediatric Oncology Patients. (CHAPATI)

Pediatric Cancer

Kenya
Ludwig-Maximilians - University of Munich

Recruiting

Lower Urinary Tract Symptoms After Intravesical Therapy (LUTSI)

Overactive Bladder | Lower Urinary Tract Symptoms | Chemotherapy Effect | Chemotherapeutic Toxicity

Germany
Rigshospitalet, Denmark

Recruiting

Investigating Cognitive Impairment in Young Patients With Cancer Prospectively (MyBrain)

Sarcoma | Leukemia | Cancer | Hodgkin Lymphoma | Non Hodgkin Lymphoma | Childhood Cancer | Chemotherapeutic Toxicity | Chemotherapy-Related Cognitive Impairment | Chemo-brain | Testicular Cancer

Denmark
NorthShore University HealthSystem

Recruiting

Mesh-Reduced Sling For Treating Stress Urinary Incontinence, Efficacy and Durability Trial

Stress Urinary Incontinence

United States
Morten Ladekarl
Odense University Hospital; Aarhus University Hospital; Vejle Hospital; Herlev... and other collaborators

Recruiting

Gemcitabine Versus Reduced-dose Combination Chemotherapy in Fragile Patients With Non-resectable Pancreatic Cancer

Pancreas Cancer | Non-Resectable Pancreas Carcinoma

Denmark
St. Petersburg State Pavlov Medical University

Recruiting

AHSCT With Fludarabine and Cyclophosphamide Based Conditioning Regimes in Patients With Multiple Sclerosis

Multiple Sclerosis

Russian Federation
Board of Trustees of Illinois State University
University of Colorado, Denver; Abbott; University of North Carolina, Greensboro and other collaborators

Recruiting

Consistently Assess Signs and Symptom of Heart Failure (CLASS-HF)

Heart Failure | Heart Failure With Reduced Ejection Fraction | Heart Failure With Preserved Ejection Fraction

United States
Universitair Ziekenhuis Brussel

Recruiting

Food Intervention to Reduce Immunotherapy toXicity (FORX01)

Dietary Habits | Immune-related Adverse Event

Belgium
Samsung Medical Center

Recruiting

Revascularization Versus Medical Treatment in Patients With Ischemic Left Ventricular Dysfunction (RESTORE-PCI)

Heart Failure With Reduced Ejection Fraction | Ischemic Cardiomyopathy

Korea, Republic of
Pulnovo Medical (Wuxi) Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Recruiting

A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure (PADN-HF-PH)

Cardiovascular Diseases | Vascular Diseases | Heart Failure | Hypertension | Pulmonary Hypertension | Heart Failure With Reduced Ejection Fraction | Heart Failure With Preserved Ejection Fraction | Heart Failure With Mid Range Ejection Fraction

China
Centro di Riferimento Oncologico - Aviano

Recruiting

Vitamin D and Head and Neck Cancer: Impact on Toxicity and Prognosis

Head and Neck Cancer

Italy
University of Florida
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Next Generation ORS: Controlled Trial Comparing ORS With Calcium vs Standard ORS in Reducing Severity of Acute Watery Diarrhea (ORS)

Diarrhea | Cholera

Bangladesh
Federal University of Rio Grande do Sul
Hospital A.C. Camargo

Recruiting

Comparison of Prophylactic Photobiomodulation Protocols in Chemoinduced Oral Mucositis in Oncology Patients

Childhood Cancer | Chemotherapeutic Toxicity | Oral Mucositis

Brazil
Sichuan Cancer Hospital and Research Institute
Sichuan Provincial People's Hospital; The Second People's Hospital of Chengdu

Not yet recruiting

Reduced Dissemination of Tumor Cells With Primary Ligation of the Inferior Mesenteric Vein in Rectal Cancer Patients.

Rectal Cancer
Institut de cancérologie Strasbourg Europe
UR 3072

Recruiting

Characterization and Kinetic of Chemotherapy-induced Cardiovascular Toxicity in Breast Cancer (PROTECT-COEUR)

Breast Cancer

France
National Medical Research Center for Cardiology...

Recruiting

Administration of the SGLT-2 Inhibitor Dapagliflozin in the Patients With Amyloid Cardiomyopathy

Heart Failure With Reduced Ejection Fraction | Heart Failure With Preserved Ejection Fraction | Heart Failure With Mid Range Ejection Fraction | Amyloid Cardiomyopathy

Russian Federation
British Columbia Cancer Agency
Princess Margaret Hospital, Canada; London Regional Cancer Program, Canada; Tom...

Not yet recruiting

Single vs. Multiple Fraction Trial of Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastases/Progression

Quality of Life | Toxicity Due to Radiotherapy | Oligometastatic Disease | Oligoprogression

Canada
Sun Yat-sen University
Zhejiang Cancer Hospital; Chongqing University Cancer Hospital; Jiangxi Provincial... and other collaborators

Recruiting

Reduced Volume of Neck Prophylactic Irradiation in Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma | Radiotherapy; Complications

China
Alexandria University

Recruiting

Effect of Empagliflozin on NT-Pro Brain Natriuretic Peptide in Heart Failure Patients With Reduced Ejection Fraction

Heart Failure With Reduced Ejection Fraction

Egypt
Universidad de Granada
University of Copenhagen; University of Oxford; Harvard University; University... and other collaborators

Recruiting

Cardiovascular Risk Prevention With a Mediterranean Dietary Pattern Reduced in Saturated Fat (CADIMED)

LDL Cholesterol

Spain
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Recruiting

Treatment of Non-ischemic Cardiomyopathies by Intravenous Extracellular Vesicles of Cardiovascular Progenitor Cells (SECRET-HF)

Heart Failure With Reduced Ejection Fraction

France
Centro Cardiologico Monzino

Recruiting

Effects of Dapagliflozin on Cardiorespiratory Parameters in Heart Failure

Heart Failure | Sleep Apnea | Heart Failure With Reduced Ejection Fraction | Cardiopulmonary Exercise Test | Left Ventricle Remodeling

Italy
Chinese University of Hong Kong

Not yet recruiting

Trial of Reduced Alteplase Dose for Parapneumonic Effusion (TRAPPE)

Pleural Infection

Hong Kong
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Ultra-hypofractioNated Adjuvant Radiotherapy ± sImultaneous Integrated Boost for Low-risk Breast Cancer Patients (UNIQUE)

Breast Cancer | Radiotherapy Side Effect

China
Duke University

Recruiting

Oxygen Toxicity: Mechanisms in Humans

Seizures | Hypercapnia | Oxygen Toxicity

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent Severe Aplastic Anemia

Recurrent Severe Aplastic Anemia | Refractory Severe Aplastic Anemia

United States
Ottawa Hospital Research Institute

Recruiting

Evaluating an Endocrine Therapy Dose-frequency Escalation Strategy and Its Effects on Tolerability and Compliance (REaCT-TEMPO)

Breast Cancer

Canada
Medical College of Wisconsin
Advancing a Healthier Wisconsin

Recruiting

Pilot Study Lp299v Supplementation in Chronic Heart Failure

Heart Failure | Heart Failure, Diastolic | Heart Failure, Systolic | Heart Failure With Reduced Ejection Fraction | Heart Failure With Preserved Ejection Fraction

United States
Centre Hospitalier Universitaire Saint Pierre

Recruiting

Cardiovascular Effects of Intrathecal Hyperbaric Prilocaine or Bupivacaine in Surgery Under Spinal Anesthesia

Spinal Anesthesia | Cardiac Toxicity

Belgium
Ain Shams University
Misr International University

Recruiting

Effect of Genetic and Epigenetic Factors on the Clinical Response and Toxicity to Cisplatin Among Egyptian Non-small Cell Lung Cancer Patients

Non Small Cell Lung Cancer | Cardiotoxicity | Nephropathy

Egypt
University of Arizona
American Heart Association

Not yet recruiting

Reduced Volume of Inspiratory Resistance Training (REVIRT)

Hypertension

United States
Julie Lemieux

Recruiting

App for Adverse Events to Oral Chemotherapy - Pilot Study

Breast Neoplasms | Chemotherapeutic Toxicity

Canada
UNC Lineberger Comprehensive Cancer Center

Recruiting

Disease Outcomes and Toxicities in Patients With Gastrointestinal and Sarcomatous Malignancies

Sarcoma | Gastrointestinal Cancer

United States
NYU Langone Health
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Time Restricted Eating for Weight Loss Maintenance (TWIST)

Obesity

United States
Vittore Buzzi Children's Hospital

Recruiting

Lung Ultrasound Guided Choice of Best Positive End-Expiratory Pressure in Neonatal Anesthesia

Oxygen Toxicity | Anesthesia; Adverse Effect

Italy
Ain Shams University

Recruiting

Effect of Genetic and Epigenetic Factors on the Clinical Response and Toxicity to Doxorubicin Among Egyptian Breast Cancer Patients

Breast Cancer

Egypt
UMC Utrecht
Julius Clinical

Not yet recruiting

Mitochondrial dysfUnction: a Key Player in Doxorubicin-induced Skeletal and Cardiac muscLE Damage (MUSCLE)

B-cell Lymphoma | Chemotherapeutic Toxicity | T-cell Lymphoma | Doxorubicin Induced Cardiomyopathy

Netherlands
Peking University Third Hospital

Not yet recruiting

Correlation Between Myocardial Injury and Intestinal Flora Changes Associated With Oncology Drug Therapy and the Preventive of Probiotics

Cancer Therapy-related Cardiovascular Toxicity

China
Peking University Third Hospital

Recruiting

Correlation Between Myocardial Injury and Intestinal Flora Changes Associated With Oncology Drug Therapy

Cancer Therapy-related Cardiovascular Toxicity

China
Bayer

Recruiting

An Observational Study, Called VERI-China, to Learn More About How Well Vericiguat Works and How Safe it is in Real-world Setting in People With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) in China (VERI-China)

Chronic Heart Failure With Reduced Ejection Fraction

China
Universitaire Ziekenhuizen KU Leuven
University Hospital, Ghent; Gasthuis Zusters Antwerpen

Recruiting

Neurocognition After Radiotherapy in CNS- and Skull-base Tumors (NARCiS)

Glioma | Pituitary Adenoma | Brain Tumor | Magnetic Resonance Imaging | Meningioma | Cognition

Belgium
University Hospital, Geneva

Recruiting

Bleeding of Unknown Cause: a Swiss Case-control Study (SWISS-BUC)

Bleeding Disorder

Switzerland
Weill Medical College of Cornell University
Cerus Corporation

Recruiting

Transfusion of Pathogen Reduced Cryoprecipitated Fibrinogen to Expedite Product Availability in Perioperative Bleeding

Bleeding | Hypofibrinogenemia

United States
Hackensack Meridian Health
Impulse Dynamics

Recruiting

Arrythmia Burden in Cardiac Contractility Modulation (CCM) (ABC)

Atrial Fibrillation | Arrythmia

United States
Rambam Health Care Campus

Recruiting

Low Dose Antenatal Corticosteroids for Late Preterm Delivery (LoDAC)

Preterm Labor | Respiratory Morbidity

Israel

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