Search clinical trials for: Severe Congenital Diaphragmatic Hernia

Total 19791 results

EndoGastric Solutions

Completed

Randomized EsophyX Versus Sham / Placebo Controlled TIF Trial: The RESPECT Study (RESPECT)

Hiatal Hernia | Gastroesophageal Reflux Disease

United States
National Eye Institute (NEI)

Completed

A Phase I/II Trial for Intravitreous Treatment of Severe Ocular Von Hippel-Lindau Disease Using a Combination of the PDGF Antagonist E10030 and the VEGF Antagonist Ranibizumab

Von Hippel-Lindau Syndrome

United States
State University of New York - Upstate Medical...
Carol M. Baldwin Breast Cancer Research Fund, Inc.

Terminated

Predictive Blood Tests for Severe Radiation Reactions in Breast Cancer Patients

Abnormalities, Radiation-Induced

United States
Hospices Civils de Lyon

Completed

BABH Study: Efficacy and Safety of Bevacizumab on Severe Bleedings Associated With Hemorrhagic Hereditary Telangiectasia (HHT). (BABH)

Telangiectasia, Hereditary Hemorrhagic | Rendu Osler Disease

France
Indiana University

Terminated

Evaluation of Glycerin Suppositories to Improve Bowel Function in Gastroschisis

Gastroschisis

United States
University of Zurich

Completed

Patients With Pulmonary Hypertension or Interstitial Lung Disease at Altitude - Effect of Oxygen on Exercise Performance

Interstitial Lung Disease | Precapillary Pulmonary Hypertension

Switzerland
Oslo University Hospital

Enrolling by invitation

Physical Activity, Motor Competence, Pulmonary Function, and Quality of Life in Children With Severe Spinal Disease

Scoliosis | Scoliosis; Juvenile | Scoliosis; Idiopathic, Infantile | Scoliosis Neuromuscular | Scoliosis in Neurofibromatosis | Scoliosis; Congenital, Postural | Scoliosis in Skeletal Dysplasia | Scoliosis Associated With Other Conditions | Scoliosis; Congenital, Due to Bony Malformation

Norway
Karolinska University Hospital
Ersta Hospital, Sweden

Completed

Partial Versus Total Fundoplication in the Surgical Repair of Para-esophageal Hernia.

Gastro Esophageal Reflux | Paraesophageal Hernia

Sweden
Omeros Corporation

Completed

A Randomized Study in Children Ages Birth Through Three Years Undergoing Unilateral Cataract Extraction With or Without Lens Replacement (ILR7)

Congenital Cataract | Unilateral Cataract Extraction

United States
CSL Behring

Terminated

CSL200 Gene Therapy in Adults With Severe Sickle Cell Disease

Anemia, Sickle Cell

United States
Christopher Dvorak

No longer available

Expanded Access Protocol (EAP) Using the CliniMACS® Device for Pediatric Haplocompatible Donor Stem Cell Transplant

Acute Myeloid Leukemia | Leukocyte Disorders | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Cytopenias | Immune Deficiency | Lymphomas | Bone Marrow Failure | Osteopetrosis | Hemoglobinopathy | Anemia Due to Intrinsic Red Cell Abnormality

United States
Baxalta now part of Shire
Baxter Healthcare, Ltd. (New Zealand), Baxter Healthcare Pty. Ltd. (Australia)

Completed

Pharmacokinetic Study of ARALAST (Human Alpha1- PI)

Alpha 1-Antitrypsin Deficiency

Australia, New Zealand
Baxalta now part of Shire

Completed

Efficacy and Safety Study of Protein C Concentrate in Subjects With Severe Congenital Protein C Deficiency

Protein C Deficiency

United States
Baxalta now part of Shire

Completed

Retrospective Study to Capture Dosing and Treatment Outcome Data in Participants With Severe Congenital Protein C Deficiency Who Were Treated With Protein C Concentrate Under an Emergency Use IND

Protein C Deficiency

United States
Minia University

Completed

Single Anastomosis Sleeve Iejenal Bypass in Obese Patient With Hiatus Hernia

Obesity, Morbid

Egypt
Eli Lilly and Company

Completed

A Study to Assess if Mirikizumab is Effective and Safe Compared to Secukinumab and Placebo in Moderate to Severe Plaque Psoriasis (OASIS-2)

Psoriasis

United States, Spain, Puerto Rico, Canada, France, Korea, Republic of, Australia, Italy, Israel, Japan, Germany, Argentina, Czechia, Hungary, Poland, United Kingdom
St. Justine's Hospital

Completed

The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery.

Trauma | Necrotizing Enterocolitis | Intestinal Obstruction | Gastroschisis | Intussusception | Intestinal Atresia | Hirschsprung Disease | Incarcerated Hernia | Malrotation | Volvulus | Meconium Ileus | Intestinal Perforation

Canada
Hospital Angeles Lomas

Enrolling by invitation

Assess the Correlation With Severe Respiratory Syncytial Virus Disease in the First 6 Months in Children With Congenital Heart Disease and Maternal Ac-AntiVSR Titers During Pregnancy ((VSRyCC))

Respiratory Syncytial Virus, Congenital Heart Disease

Mexico
Brigham and Women's Hospital
United States Department of Defense

Completed

Face Transplantation for Treatment of Severe Facial Deformity

Severe Facial Deformity

United States
Novo Nordisk A/S

Completed

A Multinational, Open-Label, Non-Controlled Trial on Safety, Efficacy and Pharmacokinetics of NNC 0129-0000-1003 in Previously Treated Paediatric Patients With Severe Haemophilia A (pathfinder™5)

Congenital Bleeding Disorder | Haemophilia A

France, United States, Switzerland, Malaysia, Brazil, Canada, Japan, United Kingdom, Israel, Portugal, Ukraine, Greece, Lithuania, Puerto Rico, Turkey, Italy
Bayer

Completed

Extension at 10 Years of the: "Observational Study Evaluating Efficacy and Costs of Secondary Prophylaxis vs On-demand Therapy With Kogenate Bayer in Patients With Severe Haemophilia A." (POTTER 10)

Hemophilia A

Italy
Children's Hospital of Philadelphia
Cigna Foundation

Completed

Impact of Serious Pediatric Illness on Parent and Sibling Health

Family Members of: Newborns Extremely Premature | Family Members of: New Pediatric Oncology Patients | Family Members of: Critical Congenital Heart Defect Patients | Family Members of: Children Severe Neurological Impairment

United States
Tami D. John
Baylor College of Medicine; The Methodist Hospital Research Institute

Terminated

Bone Marrow Transplantation, Hemoglobinopathies, SCALLOP (SCALLOP)

Sickle Cell Disease | Hemoglobin SC

United States
Shanghai Ninth People's Hospital Affiliated to...

Completed

Postoperative Follow up After Head and Face Reconstructive Surgeries

Deformity of Face

China
Al-Azhar University

Unknown

Needlescopic Inversion and Snaring Versus Ligation of Hernia Sac in Girls

Recurrent Hernia | Congenital Inguinal Hernia | Hernia Sac | Round Ligament; Injury | Fallopian Tube Injury | Ovarian Injury

Egypt
Baylor College of Medicine

Terminated

Allogeneic Stem Cell Transplantation, Severe Homzygous 0/+Thalassemia or Sever Variants of Beta 0/+ Thalassemia, THALLO (THALLO)

Thalassemia

United States
Mayo Clinic

Completed

Pasireotide LAR in Severe Polycystic Liver Disease (SOM230)

Autosomal Dominant Polycystic Kidney Disease | Polycystic Liver Disease | Autosomal Dominant Polycystic Liver Disease | Somatostatin Analogs

United States
Novo Nordisk A/S

Completed

Safety and Efficacy of Turoctocog Alfa During Long-Term Treatment of Severe and Moderately Severe Haemophilia A (guardian™ 5)

Congenital Bleeding Disorder | Haemophilia A

Italy, Sweden, Netherlands, Austria, Spain, United States, Switzerland, Germany, France, Hungary, Greece, Slovenia, Czechia, Slovakia, Poland
Duke University
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Genetics of Spina Bifida and Anencephaly

Anencephaly | Acrania

United States
NHS Lothian

Completed

Regional Blood Saturation Levels in Gastroschisis

Gastroschisis | Intestinal Ischemia
Masonic Cancer Center, University of Minnesota
National Marrow Donor Program

Completed

Stem Cell Transplant for Hemoglobinopathy

Sickle Cell Disease | Thalassemia | Severe Congenital Neutropenia | Diamond-Blackfan Anemia | Shwachman-Diamond Syndrome

United States
King's College London
Kamuzu Central Hospital; University Teaching Hospital, Lusaka, Zambia; Komfo... and other collaborators

Unknown

Multi-Centre Gastroschisis Interventional Study Across Sub-Saharan Africa

Gastroschisis

Canada, Ghana, Malawi, Tanzania, United Kingdom, Zambia
University of California, San Francisco

Terminated

Pilot Trial of Clofarabine Added to Standard Busulfan and Fludarabine for Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation

Myeloid Malignancy | Metabolic Disease | Bone Marrow Failure Syndrome | Transfusion-dependent Red Blood Cell (RBC) Defect | Congenital Immunodeficiency | Severe Immune Dysregulation

United States
Le Bonheur Children's Hospital

Completed

Sham Feeding Post-operative Infants

Newborn Morbidity | Gastroschisis | Bowel Obstruction | Short Bowel Syndrome | Oral Aversion

United States
Al-Azhar University

Completed

Laparoscopic Recurrent Inguinal Hernia Repair

Congenital Hernia

Egypt
Julia Finkel

Completed

QST-Pupillometry in Sickle Cell Disease Patients (QST)

SCD With Severe Phenotype (HbSS, HbSβ0 Thalassemia, HbSOARab)

United States
Al-Azhar University

Completed

Laparoscopic Inguinal Hernia Repair in Infancy and Childhood (LIHR-2014)

Congenital Inguinal Hernia

Egypt
Minia University

Completed

Management of Severe Congenital Blepharoptosis

Blepharoptosis

Egypt
University Hospital, Angers

Unknown

Ostomy in Continuity or Conventional Ileostomy: a Retrospective Multicentric Analysis (StomaPed)

Enterocolitis, Necrotizing | Intestinal Obstruction | Gastroschisis | Hirschsprung Disease

France
The Hospital for Sick Children
The Physicians' Services Incorporated Foundation

Terminated

Metoclopramide Pilot Trial

Gastroschisis

Canada
Emory University

Completed

Bone Marrow Transplant With Abatacept for Non-Malignant Diseases

Sickle Cell Disease | Fanconi Anemia | Hurler Syndrome | Chronic Granulomatous Disease | Severe Congenital Neutropenia | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Glanzmann Thrombasthenia | Shwachman-Diamond Syndrome | Thalassemia Major | Leukocyte... and other conditions

United States
University of Oklahoma
OU Medical Center

Completed

Compassionate Use of Omegaven in Children

Infant, Premature, Diseases | Cholestasis | Gastroschisis | Intestinal Atresia | Short Bowel Syndrome | Cholestasis of Parenteral Nutrition | Total Parenteral Nutrition-induced Cholestasis

United States
Zagazig University

Completed

Double Mesh Modification of Incisional Hernia Can be Effective Without Severe Local Complications

Incisional Hernia of Midline of Abdomen | Incisional Hernia of Midline of Upper Abdomen | Incisional Hernia of Midline of Lower Abdomen

Egypt
Grubnik Volodymyr

Completed

Approach to Hiatal Hernia Repair Based on Collagen Study

Hiatal Hernia | Gastroesophageal Reflux Disease
Novartis Pharmaceuticals

Terminated

Safety and Efficacy of Deferasirox in Combination With Desferoxamine in β-thalassaemia Patients With Severe Cardiac Iron Overload

Cardiac Iron Overload | Transfusion-dependent β-thalassemia Patients

Greece
Miromatrix Medical Inc.

Completed

Complications, Outcomes and Revisions Following Hiatal Hernia Repair With MIROMESH

Gastroesophageal Reflux | GERD | Hiatal Hernia With Gastroesophageal Reflux Disease

United States
Roswell Park Cancer Institute

Completed

Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Primary Myelofibrosis | Polycythemia Vera | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma and other conditions

United States
Miromatrix Medical Inc.

Completed

Miromatrix Biological Mesh for Hiatal Hernia Repair

Hiatal Hernia

United States
Instituto de Investigacion Sanitaria La Fe

Unknown

Utility of a Supraaponeurotic Mesh as Prophylaxis of the Midline Eventration After an Oncological Colorrectal Resection

Eventration

Spain
The Hospital for Sick Children

Completed

Dynamic Contrast Enhanced Magnetic Resonance Perfusion Imaging in Congenital Heart Disease and Lung Disease

Asthma | Cystic Fibrosis | Heart Disease

Canada

Search clinical trials for: Severe Congenital Diaphragmatic Hernia

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