Search clinical trials for: de novo lesions

Total 486804 results

National Cancer Institute (NCI)

Enrolling by invitation

Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Center for Immuno-Oncology Studies

Cervical Intraepithelial Neoplasia | Oropharyngeal Neoplasms | Squamous Intraepithelial Lesions of the Cervix | Cervical Neoplasms | Hematologic Malignacies

United States
Turku University Hospital

Active, not recruiting

Prospective Clinical Safety and Efficacy Study of Lesion-targeted MRI-TULSA for Localized Prostate Cancer (PRO-TULSA-PC)

Localized Prostate Cancer

Finland
Abbott Medical Devices

Completed

Abbott Next Generation Drug Eluting Stent 48mm Study (SPIRIT 48)

Coronary Artery Disease

United States, Australia, Taiwan
Thomas Jefferson University
National Cancer Institute (NCI)

Terminated

Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions

Oral Cavity Carcinoma | Leukoplakia | Erythroplakia | Proliferative Verrucous Leukoplakia

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer

Cervical Intraepithelial Neoplasia | Cervical Adenocarcinoma | Cervical Squamous Cell Carcinoma, Not Otherwise Specified | Vaginal Adenocarcinoma | Vulvar Intraepithelial Neoplasia | Stage I Cervical Cancer AJCC v8 | Stage IA Cervical Cancer AJCC v8 | Stage IA1 Cervical Cancer AJCC v8 | Stage IA2 Cervical... and other conditions

United States
IRCCS San Raffaele

Terminated

Ex-vivo Ultrasound Guided Radiofrequency Ablation on Pancreatic Solid Lesions

Pancreatic Cancer | Radiofrequency Ablation | Endoscopic Ultrasound

Italy
University Hospital, Brest

Active, not recruiting

Comparison of MORbidity of Submucosal DIssection Resection of Giant cOlon Lesions Versus Surgery: a National Multicenter Study (MORDIGO) (MORDIGO)

Colonic Neoplasms

France
Rockefeller University

Completed

A Study Investigating the Safety and Tolerability of an Immune Treatment in Cancer Patients With Lesions to the Skin

Cancer | Solid Tumor | Cancer of Skin

United States
University Medical Center Groningen

Completed

VEGF-targeted Fluorescence Near-Infrared (NIR) Endoscopy in (Pre)Malignant Esophageal Lesions (VICE)

Esophageal Cancer | Dysplasia

Netherlands
University Medical Center Groningen

Completed

Molecular Fluorescence Endoscopy of (Pre)Malignant Esophageal Lesions (EAGLE)

Esophageal Cancer | Barrett Esophagus | Dysplasia in Barrett Esophagus

Netherlands
Centre Hospitalier Universitaire de Saint Etienne

Completed

Comparison of Dermatoscopy X400 Interpreted by 6 Non-dermatologists and an Artificial Intelligence Software Skin Artificial Intelligence Versus Dermatoscopy x 20

Pigmented Lesions | Genital Tumor

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Contrast-enhanced MRI in Detecting Benign and Malignant Liver Lesions

Hepatocellular Carcinoma | Liver and Intrahepatic Bile Duct Disorder | Metastatic Malignant Neoplasm in the Liver | Primary Malignant Liver Neoplasm

United States
Children's Hospital of Philadelphia

Available

18F-L-Fluoro-DOPA PET/CT Scan Localization of Focal Pancreatic Lesions in Subjects With Hyperinsulinemic Hypoglycemia

Insulinoma | Beckwith-Wiedemann Syndrome | Congenital Hyperinsulinism (CHI)

United States
Procare Health Iberia S.L.
Adknoma Health Research

Active, not recruiting

Clinical Trial to Explore Papilocare Gel Efficacy to Repair of the Cervico-vaginal Mucosa With HPV High Risk Lesions. (PALOMA2)

Human Papilloma Virus Infection | Human Papilloma Virus | Cervix Lesion

Spain
Huazhong University of Science and Technology
LanZhou University; The Affiliated Nanjing Drum Tower Hospital of Nanjing University...

Completed

Artificial Intelligence in EUS for Diagnosing Pancreatic Solid Lesions

Pancreatic Ductal Adenocarcinoma | Pancreatitis, Chronic | Pancreatic Neuroendocrine Tumor | Autoimmune Pancreatitis

China
Xijing Hospital

Active, not recruiting

Paclitaxel-coated Balloon for Treatment of De-novo Non-complex Coronary Artery Lesions

Coronary Artery Disease | De Novo Stenosis

China
Sichuan Cancer Hospital and Research Institute

Completed

Association Between Surgical Timing and Route of Total Hysterectomy After LEEP and Perioperative Risk in Patients With Cervical HSIL

High-Grade Squamous Intraepithelial Lesions

China
Azienda USL Modena

Completed

Endoscopic Submucosal Dissection of Large Recto-sigmoid Lesions Under Spinal Anesthesia

Colorectal (Colon or Rectal) Cancer

Italy
British Columbia Cancer Agency
Canadian Institutes of Health Research (CIHR)

Terminated

OCT-AF Imaging of Pre-cancers of Vulva and Cervix

Cervical Cancer | Vulvar Cancer | Precancerous Lesions | Cervical Dysplasia | Vulvar Dysplasia

Canada
Ain Shams University

Active, not recruiting

Comparative Study Between Isolated Iliac Vein Stenting Versus Concomitant Iliac Vein Stenting With Pelvic Vein Embolization in Patients With Pelvic Venous Insufficiency Secondary to Nonthrombotic Iliac Vein Lesions

Pelvic Congestive Syndrome | Nonthrombotic Iliac Vein Lesions

Egypt
Ascelia Pharma AB

Completed

Safety and Diagnostic Efficacy of Mangoral in Participants With Focal Liver Lesions and Reduced Kidney Function (SPARKLE)

Severe Renal Impairment | Known or Suspected Focal Liver Lesions

United States, Italy, Germany, Poland, Russian Federation, Sweden, Turkey, Argentina, Colombia, Mexico
University Health Network, Toronto

Completed

Comparison Between Dual Energy/Subtraction CT With MRI for the Identification of Predictors of Malignancy in Cystic Pancreatic Lesions

Pancreatic Cyst

Canada
Boston Scientific Corporation

Withdrawn

iNod™ Ultrasound-Guided Needle Biopsy System Study

Multiple Pulmonary Nodules | Solitary Pulmonary Nodule | Biopsy, Fine-Needle

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); The Emmes Company, LLC; Inovio Pharmaceuticals

Active, not recruiting

VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions

Anal Intraepithelial Neoplasia | High Grade Squamous Intraepithelial Neoplasia | HIV Positivity | Human Papillomavirus-16 Positive | Human Papillomavirus-18 Positive

United States, Puerto Rico
Auris Health, Inc.

Completed

Transbronchial Biopsy Assisted by Robot Guidance in the Evaluation of Tumors of the Lung (TARGET)

Lung Cancer | Pulmonary Nodule

United States, Canada, China
Rush University Medical Center

Active, not recruiting

MRI Guided SBRT for Localized Prostate Cancer

Prostate Cancer

United States
Memorial Sloan Kettering Cancer Center

Completed

Vemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid Cancers

Thyroid Cancer, Papillary | Thyroid Cancer, Follicular | Thyroid Carcinoma | Thyroid Cancer | Thyroid Cancer (Follicular Cell) | BRAF V600E Mutation Positive

United States
Xijing Hospital of Digestive Diseases

Completed

A Study on the Relationship Between Gastric Xanthoma and Gastric Cancer and Precancerous Lesions

Gastric Cancer | Helicobacter Pylori Infection | Intestinal Metaplasia | Precancerous Lesions | Gastric Xanthoma

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

HPV Vaccine Therapy in Interrupting Progression in Patients With High-Grade Vulvar or Anal Lesions

High Grade Anal Canal Intraepithelial Neoplasia | High Grade Vulvar Squamous Intraepithelial Lesion

United States
Crescendo Biologics Ltd.
University Medical Center Groningen

Active, not recruiting

A Phase I Study to Assess PSMA+ and PSMA- Tumour Lesions

Advanced and/or Metastatic Solid Tumours

Netherlands
Dana-Farber Cancer Institute

Active, not recruiting

PORTAL: Patient-reported Outcomes After Routine Treatment of Atypical Lesions

Breast Cancer

United States
Karolinska Institutet

Active, not recruiting

Multi-omics Analyses on Etiology and Early Detection of Stomach Cancer Precursor Lesions

Chronic Atrophic Gastritis

Sweden
Nobelpharma

Active, not recruiting

Clinical Study of NPC-12Y Gel in Patients With Skin Lesions Associated With TSC

Tuberous Sclerosis Complex

Japan
Centre hospitalier de l'Université de Montréal...

Completed

Evaluation of Deployment Capability and Accuracy of an Outside the Scope (OTS), Detachable Catheter System for Ablation of Peripheral Lung Lesions: An Ex-Vivo Human Lung Model Study

Lung Cancer

Canada
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Study of the Nevisense Device to Assess Atypical Skin Lesions

Nevus | Skin Lesion | Multiple Nevi | Large Acquired Nevi

United States
Centre Hospitalier Universitaire de Nice

Terminated

Interest of the Confocal Microscope in the Diagnosis of Epidermoid Carcinoma of the Vulva and Their Precursors

Vulvar Intraepithelial Neoplasia | Vulvar Mucosa Lesions

France
Xijing Hospital

Active, not recruiting

Paclitaxel-Coated Balloon Versus Zotarolimus-Eluting Stent for Treatment of De Novo Coronary Artery Lesions (CAGE-FREEIII)

Coronary Artery Disease | Percutaneous Coronary Intervention | De Novo Stenosis

China
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, Los Angeles; Merck... and other collaborators

Active, not recruiting

HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV (COVENANT)

HIV Infection | AIDS-Related Human Papillomavirus Infection | High Grade Cervical Squamous Intraepithelial Neoplasia

Uganda, Kenya, Zimbabwe, South Africa, Malawi
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Studying a New Piece of Equipment That Can Help Plan Radiation Therapy of the Spine

Thoracic Neoplasms | Thoracic Cancer | Thoracic Diseases | Spine Metastases | Spine Disease | Spine Cancer

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC

Active, not recruiting

Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions

HIV Infection | Anal Intraepithelial Neoplasia | High-grade Squamous Intraepithelial Lesion

United States, Puerto Rico
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, San Francisco; University... and other collaborators

Active, not recruiting

Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions (ANCHOR)

HIV Infection | Anal Cancer | Human Papilloma Virus Infection | High-grade Squamous Intraepithelial Lesion

United States, Puerto Rico
Boston Scientific Corporation

Terminated

Tracking Renal Tumors After Cryoablation Evaluation (TRACE)

Kidney Neoplasms

United States
Tanta University

Completed

Bone Lid Technique Versus Standard Technique for Treatment of Mandibular Lesions

Mandibular Diseases | Mandible Tumor | Mandible Cyst

Egypt
Zhejiang University
Lanxi Hospital of Traditional Chinese Medicine; Lanxi Red Cross Hospital

Active, not recruiting

Lifestyle and Dietary Pattern in Relation to Precursor Lesions of Colorectal Cancer and Cardiometabolic Diseases

Cardiovascular Diseases | Polyps

China
M.D. Anderson Cancer Center

Withdrawn

Robotic Bronchoscopy With Cone CT and Indocyanine Green to Aid Removal of Lung Lesions in Patients With Stage I Non-small Cell Lung Cancer or Lung Metastases, REPLACING Study

Lung Non-Small Cell Carcinoma | Stage I Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Lung

United States
Centre Hospitalier William Morey - Chalon sur Saône

Completed

Structural Description of Skin Biopsies With Dynamic Full-field Optical Coherence Tomography on Suspected Basal Cell Carcinoma Lesions, a Pilot Study (DOCTOBA) (DOCTOBA)

Basal Cell Carcinoma | Tomography, Optical Coherence

France
Fundacin Biomedica Galicia Sur

Completed

Clinical Validation of PolyDeep: an Artificial Intelligence-based Computer-aided Polyp Detection (CADe) and Characterization (CADx) System. Polydeep Advance 2.

Colorectal Cancer

Spain
Peking University People's Hospital
BeijingNewBiorayTechnologyCo.,Ltd.; Hangzhou Newhorizon Health Technology Co...

Active, not recruiting

Primary Cervical Cancer Screening by Self-sampling HPV Test (PREVENT)

Cervical Cancer | Cervical Adenocarcinoma | Cervical Squamous Cell Carcinoma | Human Papillomavirus Infection | Adenocarcinoma in Situ | Low-Grade Squamous Intraepithelial Lesions | High-Grade Squamous Intraepithelial Lesions | Cervical Intraepithelial Neoplasia Grade II | Cervical Intraepithelial Neoplasia... and other conditions

China
The University of Texas Health Science Center,...
Texas Neurofibromatosis Foundation

Completed

Everolimus for Treatment of Disfiguring Cutaneous Lesions in Neurofibromatosis1 CRAD001CUS232T (DCLNF1)

Neurofibromatosis 1

United States
Norbert Avril, M.D.

Completed

Digital PET/CT Using [Ga-68]PSMA for Characterization of Prostate Lesions

Prostate Cancer

United States

Search clinical trials for: de novo lesions

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