Search clinical trials for: moderate to severe Alzheimer's disease

Total 477050 results

Stephen Robert Marder

Not yet recruiting

MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder

Post Traumatic Stress Disorder

United States
ApcinteX Ltd
Centessa Pharmaceuticals plc

Recruiting

The Efficacy and Safety of SerpinPC in Participants With Severe Hemophilia A or Moderately Severe to Severe Hemophilia B (PRESent-2)

Hemophilia A | Hemophilia B

United States, Italy, Spain, Taiwan, Australia, Belgium, United Kingdom, France, Germany, India, South Africa, Canada, Poland, Armenia, Turkey
Landos Biopharma Inc.

Recruiting

Study to Evaluate the Clinical Activity and Safety of Oral NX-13 in Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

United States, Belgium, Italy, Poland
Eli Lilly and Company

Recruiting

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis (SHINE-2)

Ulcerative Colitis

United States, Canada, Poland, Japan, Belgium, Israel, Portugal, Korea, Republic of, France, Australia, Italy, Netherlands, Germany, United Kingdom
AbbVie

Recruiting

Study to Assess Adverse Events, Change in Disease Activity, and How Oral Upadacitinib Moves Through the Body of Pediatric Participants With Moderately to Severely Active Ulcerative Colitis.

Ulcerative Colitis

United States, Japan, Spain, Korea, Republic of, Taiwan, Bulgaria, Italy, Poland, France, United Kingdom, Greece, New Zealand, Australia, Belgium, Israel, Hungary, Netherlands
ReAlta Life Sciences, Inc.
Premier Research Group plc

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia (STAR)

Hypoxic-Ischemic Encephalopathy

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Recruiting

A Study of CM326 in Subjects With Moderate to Severe Asthma

Moderate to Severe Asthma

China
Hangzhou Highlightll Pharmaceutical Co., Ltd

Recruiting

The Efficacy and Safety of TLL018 in Moderate-to-severe Plaque Psoriasis

Plaque Psoriasis

United States
Sanofi

Recruiting

Open Label, Long-term Study Evaluating Safety and Efficacy of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis (ATLANTIS)

Dermatitis Atopic

Italy, United Kingdom, Argentina, France, Chile, Czechia, Germany, Japan, Spain, China, Netherlands, Brazil, Canada, Denmark, Korea, Republic of, South Africa, Taiwan, Poland, India, Mexico
Eli Lilly and Company

Recruiting

A Study of Mirikizumab (LY3074828) in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT-URGE)

Ulcerative Colitis | Ulcerative Colitis Chronic

United Kingdom, United States, Poland, Czechia, Hungary, Italy, France, Slovakia, Germany, Belgium
Wuhan Union Hospital, China

Recruiting

Effect of APRV and LTV on Lung Ventilation and Perfusion in Patients With Moderate-to-severe ARDS

Acute Respiratory Distress Syndrome

China
Shanghai Ming Ju Biotechnology Co., Ltd.

Recruiting

CD19-CART(Relma-cel) for Moderate to Severe Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

China
Chulalongkorn University

Recruiting

Effects of Lemborexant as a Treatment for Moderate-to-severe OSA Patients With Low Arousal Threshold (LOSALAT)

OSA

Thailand
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Recruiting

A Study of CM310 in Subjects With Moderate to Severe Asthma

Moderate to Severe Asthma

China
Jiangsu Yahong Meditech Co., Ltd aka Asieris

Recruiting

A Phase 1b Study to Evaluate APL-1401 in Patients With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

United States
Nuance Pharma (shanghai) Co., Ltd
Laboratory Corporation of America

Recruiting

A Study to Evaluate the Efficacy and Safety of Ensifentrine for 24 Weeks in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

China
University of North Carolina, Chapel Hill
Chiesi USA, Inc.

Recruiting

Inhaled Mannitol on Mucociliary Clearance in Moderate to Severe Cystic Fibrosis

Cystic Fibrosis

United States
Eli Lilly and Company

Recruiting

A Study to Assess the Long-Term Safety and Efficacy of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis (ADorable-2)

Eczema | Atopic Dermatitis

United States, Taiwan, Spain, Mexico, Japan, Brazil, Australia, Canada, Czechia, France, Germany, Argentina, Poland
IRCCS San Raffaele

Recruiting

Comparison Between Bowel Ultrasound-based Treat to Target Versus Routine Treat to Target Strategies in Ulcerative Colitis

Ulcerative Colitis Chronic Moderate | Ulcerative Colitis Chronic Severe

Italy
University Hospital, Tours

Recruiting

Intensification of Blood Pressure Lowering Therapeutics Based on Diuretics Versus Usual Management for Uncontrolled Hypertension IN Patients With Moderate to Severe Chronic Kidney Disease (THINK)

Uncontrolled Hypertension | Chronic Kidney Disease(CKD)

France
Sanofi
Regeneron Pharmaceuticals

Recruiting

A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab))

Colitis Ulcerative

Argentina, Korea, Republic of, Mexico, United States, Canada, Chile, Japan, Puerto Rico, South Africa, Taiwan, Turkey
RegenLab France SAS

Recruiting

Combination of PRP and XLHA Prepared With RegenMatrix Medical Device To Treat Moderate to Severe Knee Osteoarthritis

Knee Osteoarthritis

France
Keymed Biosciences Co.Ltd

Recruiting

Study of CM310 Injection in Subjects With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis

China
Amgen

Recruiting

A Study to Evaluate Rocatinlimab (AMG 451) in Adolescent Subjects With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-ASTRO)

Atopic Dermatitis

United States, Korea, Republic of, Taiwan, Spain, Croatia, China, Greece, Belgium, Thailand, Puerto Rico, Hungary, Poland, Germany, Brazil, Italy, Japan, Canada, France, Romania, Chile
Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

Pharmacodynamic Blood Characteristics of ICP-332 in Patients With Moderate to Severe Atopic Dermatitis

Moderate to Severe Atopic Dermatitis

China
Koite Health Oy
Lithuanian University of Health Sciences; University of Helsinki

Recruiting

Regular Home-use of Dual-light Photodynamic Therapy in the Management of Chronic Stage III-IV Periodontitis

Periodontitis Chronic Generalized Moderate | Periodontitis Chronic Generalized Severe

Lithuania
ASLAN Pharmaceuticals

Recruiting

Study of Eblasakimab in Male or Female Moderate-to-Severe Atopic Dermatitis Patients Previously Treated With Dupilumab

Atopic Dermatitis

United States, Canada
The First Affiliated Hospital of Hunan University...

Recruiting

Acupuncture as an Adjunctive Therapy for Covid-19 Omicron Randomised Controlled Trial in Patients With Moderate/Severe Pneumonia (ZCFZZLXGBDFYHZ)

Pulmonary Function | Acupuncture | Covid-19 Omicron

China
Pfizer

Recruiting

A Study to Learn About Abrocitinib in Adult Patients With Moderate to Severe Atopic Dermatitis. (ADAIR)

Eczema | Atopic Dermatitis

France
Poitiers University Hospital

Recruiting

Early High-flow Oxygen Therapy With nebuLized Beta-2-agonist Using a Vibrating Mesh for the Management of Moderate to Severe Asthma Exacerbation in the Emergency Department (EOLE)

Moderate Asthma Exacerbation | Severe Asthma Exacerbation

France
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Recruiting

A Phase III Extended Clinical Trial of Jaktinib Hydrochloride Tablets in the Treatment of Moderate and Severe Atopic Dermatitis

Atopic Dermatitis

China
Frontier Biotechnologies Inc.

Recruiting

Evaluate the Efficacy and Safety of FB2001 for Inhalation in Patients With Mild to Moderate COVID-19

Mild to Moderate COVID-19

China
Amgen

Recruiting

Long-term Safety and Efficacy of Efavaleukin Alfa in Participants With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

United States, Germany, Japan, Denmark, Romania, Argentina, Bulgaria, Hungary, Korea, Republic of, Mexico, Poland, Switzerland, Turkey
Keymed Biosciences Co.Ltd

Recruiting

The Study of CM326 in Moderate-to-severe Atopic Dermatitis

Moderate-to-severe Atopic Dermatitis

China
AbbVie

Recruiting

An Observational Study to Assess Change in Disease Activity and Use of Upadacitinib Tablets in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis in Real World (UPDATE)

Atopic Dermatitis

France
Teva Branded Pharmaceutical Products R&D, Inc.
Sanofi

Recruiting

A Study to Evaluate the Long-Term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease

Crohn Disease | Colitis, Ulcerative

United States, Hungary, Poland, Czechia, Japan, Belgium, Spain, Bulgaria, France, Italy, Slovakia, Austria
Regeneration Biomedical, Inc.

Recruiting

Autologous Activated Adipose-derived Stem Cells (RB-ADSC) Injected Directly Into the Brain for Mild to Moderate Alzheimer's Disease

Alzheimer Disease

United States
Taipei Medical University Hospital

Recruiting

Effects of Multiple Mega-dose of Vitamin D3 Supplementation on Ameliorating Moderate to Severe Chronic Pain in Hemodialysis Patients

Hyperparathyroidism | Chronic Pain | Hemodialysis

Taiwan
Instituto de Investigación Sanitaria de la Fundación...

Not yet recruiting

Benefits of an Aerobic and Strength Rehabilitation Program With Post- SARS-CoV-2 Patients Moderate-severe (SARS-CoV-2)

COVID-19

Spain
Peijia Medical Technology (Suzhou) Co., Ltd.

Recruiting

Safety and Efficacy of the GeminiOne Transcatheter Valve Edge-to-Edge Repair System in Patients With Moderate-severe or Severe Degenerative Mitral Regurgitation

Mitral Regurgitation | Degenerative Mitral Valve Disease

China
Bristol-Myers Squibb

Recruiting

A Study to Evaluate Efficacy and Long-term Safety of Oral Ozanimod in Chinese Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Ulcerative Colitis

China, Taiwan
MurciaSalud

Recruiting

Impact of a PERsonalized CAse MAnagement Program for the Follow-up of Moderate and Severe aSTHma Patients on Exacerbations, Health Resource Use and Asthma Control: PERCASTHMA STUDY (PERCASTHMA)

Asthma | Telemedicine | Case Management

Spain
Jazz Pharmaceuticals

Recruiting

A Study of Suvecaltamide in Adults With Moderate to Severe Residual Tremor in Parkinson's Disease

Parkinson Disease | Tremor

United States, Spain, Germany, Poland
Cognito Therapeutics, Inc.

Recruiting

A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011) (Hope)

Cognitive Impairment | Dementia | Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline | Alzheimer Disease, Early Onset | Alzheimer Disease, Late Onset | MCI | Dementia Alzheimers | Mild Dementia | Dementia of Alzheimer Type | Cognitive Impairment, Mild | Alzheimer Disease 1 | Dementia, Mild | Alzheimer... and other conditions

United States
Indiana University

Recruiting

Intervention to Change Affect Recognition and Empathy (ICARE)

Traumatic Brain Injury | Concussion, Severe | Concussion, Intermediate | Concussion With Brief Loss of Consciousness | Traumatic Brain Injury With Brief Loss of Consciousness | Traumatic Brain Injury With No Loss of Consciousness | Concussion With LOC 31 to 59 Minutes | Traumatic Brain Injury With... and other conditions

United States
Incyte Corporation

Recruiting

A Study to Evaluate the Efficacy and Safety of Povorcitinib (INCB054707) in Participants With Moderate to Severe Hidradenitis Suppurativa (HS) (STOP-HS2)

Hidradenitis Suppurativa (HS)

United States, Canada, Bulgaria, Italy, Spain, Germany, Poland, France, Australia, Denmark, United Kingdom
Incyte Corporation

Recruiting

A Study to Evaluate the Efficacy and Safety of Povorcitinib (INCB054707) in Participants With Moderate to Severe Hidradenitis Suppurativa (STOP-HS1)

Hidradenitis Suppurativa (HS)

United States, Austria, Canada, Czechia, Spain, Germany, Poland, Netherlands, Belgium, France, Greece, Japan
University of Exeter
Royal Devon and Exeter NHS Foundation Trust

Recruiting

Stimulated Glucagon as a Biomarker of Hypoglycemic Risk in Type 1 Diabetes (MUGGLE)

Hypoglycemia | Type 1 Diabetes

United Kingdom
Ralph H. Johnson VA Medical Center
JHSPH Center for Clinical Trials

Not yet recruiting

Dronabinol for Agitation in Dementia Crossover Trial

Behavioral Symptoms | Agitation,Psychomotor | Dementia Moderate | Dementia Severe

United States
Morphic Therapeutic, Inc

Recruiting

A Study to Evaluate MORF-057 in Adults With Moderately to Severely Active UC (EMERALD-2)

Inflammatory Bowel Diseases | Colitis, Ulcerative

United States, Germany, Korea, Republic of, Italy, Poland, Australia, Georgia, Austria, Bulgaria, Czechia, Estonia, France, Hungary, India, Israel, Latvia, Lithuania, Romania, Serbia, Slovakia, Taiwan

Search clinical trials for: moderate to severe Alzheimer's disease

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