Clinical Trials Sponsored by Shield Holdings

Total 3131 results

NICHD Pelvic Floor Disorders Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Combined Treatment for Mixed Incontinence (ESTEEM)

Urinary Incontinence, Stress | Urinary Incontinence, Urge

United States
National Institute of Diabetes and Digestive and...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

The Diabetes Prevention Trial of Type 1 Diabetes (DPT-1) (DPT-1)

Diabetes Mellitus, Type 1

United States, Canada
Eunice Kennedy Shriver National Institute of Child...
University of Pennsylvania; University of Alabama at Birmingham; Duke University and other collaborators

Recruiting

Study of Pregnancy And Neonatal Health (SPAN) (SPAN)

Gestational Diabetes Mellitus

United States
Yale University
Johns Hopkins University; University of Colorado, Denver; Eunice Kennedy Shriver... and other collaborators

Recruiting

Genomic Predictors of Recurrent Pregnancy Loss (GPRPL)

Recurrent Pregnancy Loss

United States
Shandong University
Shandong Provincial Hospital; Qianfoshan Hospital; Jinan Central Hospital; The... and other collaborators

Recruiting

Therapeutic Drug Monitoring of Teicoplanin in Children

Bacterial Infections

China
Children's Hospital Medical Center, Cincinnati
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Adolescent Sexually Transmitted Infection Screening in the Emergency Department (STI)

Chlamydia | Gonorrhea

United States
Ludwig-Maximilians - University of Munich
Bavarian State Ministry of Environment, Public Health and Consumer Protection and other collaborators

Completed

Population Based Intervention to Prevent Obesity in Kindergartens (TigerKids)

Obesity
National Institute of Diabetes and Digestive and...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

ATG-GCSF in New Onset Type 1 Diabetes (ATG-GCSF)

Diabetes Mellitus, Type 1

United States
University of British Columbia
Eli Lilly and Company; Merck Sharp & Dohme LLC; Pfizer; Canadian Institutes of... and other collaborators

Recruiting

National Active Surveillance Network and Pharmacogenomics of Adverse Drug Reactions in Children

Adverse Drug Reaction (ADR)

Canada
Children's Mercy Hospital Kansas City
Karolinska University Hospital; University of Southampton; KK Women's and Children... and other collaborators

Completed

Appendectomy Versus Non-Operative Treatment For Acute Non-Perforated Appendicitis in Children (APPY)

Appendicitis

United States
Xingwang Zhu
University of Southern California; Children's Hospital of Fudan University; The... and other collaborators

Completed

NHFOV vs. NCPAP as a Primary Treatment to Neonatal Respiratory Distress Syndrome(NRDS)

Preterm Infants

China
The First Affiliated Hospital with Nanjing Medical...
The First Affiliated Hospital of Anhui Medical University; RenJi Hospital; The... and other collaborators

Completed

Cumulative Live Birth Rates After Cleavage-stage Versus Blastocyst-stage Embryo Transfer (CLBR-CBSET)

Infertility

China
NICHD Pelvic Floor Disorders Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Controlling Anal Incontinence by Performing Anal Exercises With Biofeedback or Loperamide (CAPABLe) (CAPABLe)

Fecal Incontinence

United States
a2 Milk Company Ltd.
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine and other collaborators

Completed

Comparative Effects of a2 Platinum Stage 1 Infant Formula on Infant Digestion and Comfort

Healthy Infants

China
NICHD Pelvic Floor Disorders Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Apical Suspension Repair for Vault Prolapse In a Three-Arm Randomized Trial Design (ASPIRe)

Visceral Prolapse

United States
Peking Union Medical College Hospital
The First Affiliated Hospital of Nanchang University; Southwest Hospital, China and other collaborators

Recruiting

A Multi-center Registry Study: The Follow-up the Complications for Trans-vaginal Mesh Surgery

Pelvic Organ Prolapse

China
Brigham and Women's Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy Infants

Genetic Predisposition to Disease | Hereditary Diseases

United States
University Hospital, Gasthuisberg
The University of Texas Health Science Center, Houston; Hospital Clinic of... and other collaborators

Completed

Tracheal Occlusion To Accelerate Lung Growth (TOTAL) Trial for Severe Pulmonary Hypoplasia (TOTAL)

Congenital Diseases | Pulmonary Hypoplasia | Diaphragmatic Hernia

United Kingdom, Canada, United States, Belgium, Italy, Germany, France, Japan, Australia, Poland, Spain
China Academy of Chinese Medical Sciences
Renmin Hospital of Wuhan University; Children's Hospital of Soochow University and other collaborators

Unknown

Clinical Study of Reduning Injection for the Treatment of Influenza in Children

Influenza in Children
University College Cork
Institut National de la Santé Et de la Recherche Médicale, France; KU Leuven; University of Alberta and other collaborators

Terminated

Management of Hypotension In the Preterm Infant (HIP)

Hypotension | Low Blood Pressure | Intraventricular Hemorrhage of Prematurity

Canada, Ireland, Belgium, Czechia, United Kingdom
University of Alabama at Birmingham
University of Colorado, Denver; Eunice Kennedy Shriver National Institute of... and other collaborators

Completed

Genetic and Physical Characteristics of Rett Syndrome

Rett Syndrome | MECP2 Duplication Disorder | Rett-related Disorder

United States
Women's Hospital School Of Medicine Zhejiang University
Sun Yat-sen University; Qilu Hospital of Shandong University; Second Affiliated... and other collaborators

Recruiting

Nab-paclitaxel Versus Sb-taxanes As First-Line Treatment in Advanced Ovarian Cancer

Epithelial Ovarian Carcinoma Stage III | Epithelial Ovarian Carcinoma Stage IV | Fallopian Tube Carcinoma Stage III | Fallopian Tube Carcinoma Stage IV | Primary Peritoneal Carcinoma Stage III | Primary Peritoneal Carcinoma Stage IV

China
Yale University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies (CRETE)

Deep Venous Thrombosis

United States
FHI 360
University of Washington; University of North Carolina, Chapel Hill; World Health... and other collaborators

Completed

The Evidence for Contraceptive Options and HIV Outcomes Trial (ECHO)

HIV | Contraception

Kenya, South Africa, Swaziland, Zambia
Daping Hospital and the Research Institute of Surgery...
The First Affiliated Hospital of Anhui Medical University; LanZhou University; Beijing 302 Hospital and other collaborators

Withdrawn

Invasive Ventilation for Neonates With Acute Respiratory Distress Syndrome(ARDS)

Acute Respiratory Distress Syndrome | Conventional Mechanical Ventilation | High Frequency Oscillation Ventilation

China
Daping Hospital and the Research Institute of Surgery...
The First Affiliated Hospital of Anhui Medical University; LanZhou University; Beijing 302 Hospital and other collaborators

Withdrawn

Selective High Frequency Oscillatory Ventilation (HFOV) for Neonates

Acute Respiratory Distress Syndrome | Respiratory Distress Syndrome | High Frequency Oscillatory Ventilation

China
Chongqing University Cancer Hospital
Zhejiang Cancer Hospital; Sun Yat-sen University; Fujian Cancer Hospital; Tongji... and other collaborators

Recruiting

The Efficacy of Lymph Node Dissection for Stage IIICr of Cervical Cancer(CQGOG0103)

Cervical Cancer

China
Maja Thiele
University of Oslo; Novo Nordisk A/S; University of Copenhagen; University of Southern... and other collaborators

Recruiting

Screening At-risk Populations for Hepatic Fibrosis With Non-invasive Markers (SIPHON)

Fibrosis | Liver Diseases, Alcoholic

Denmark
Harbin Medical University
Peking University First Hospital; The Second Hospital of Hebei Medical University and other collaborators

Completed

EROSION III: OCT- vs Angio-based Reperfusion Strategy for STEMI

ST-segment Elevation Myocardial Infarction

China
China Academy of Chinese Medical Sciences
Peking University First Hospital; Peking Union Medical College Hospital; Chengdu... and other collaborators

Unknown

A Clinical Study on Kangfu Anti-inflammatory Suppository of Gynaecology Combined With Antibiotics for Pelvic Inflammatory Diseases (Evidence of Dampness and Heat Accumulation)

Pelvic Inflammatory Diseases
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
The First Affiliated Hospital of Nanchang University; Guangzhou First People... and other collaborators

Recruiting

Treateament of Newly Diagnosed Acute Monocytic Leukemia in Children (SCCLG-M5)

Leukemia, Monocytic, Acute | Pediatric AML

China
Albert Einstein College of Medicine
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

ScreenPlus: A Comprehensive, Flexible, Multi-disorder Newborn Screening Program (ScreenPlus)

Mucopolysaccharidosis II | Fabry Disease | Niemann-Pick Disease, Type C | Mucopolysaccharidosis VI | Lysosomal Acid Lipase Deficiency | Metachromatic Leukodystrophy | Gaucher Disease | Cerebrotendinous Xanthomatosis | Mucopolysaccharidosis IV A | GM1 Gangliosidosis | Mucopolysaccharidosis VII | Acid Sphingomyelinase... and other conditions

United States
Tuberculosis Research Centre, India
All India Institute of Medical Sciences, Bhubaneswar; Institute of Child Health... and other collaborators

Suspended

BCG Revaccination in Children and Adolescents (BRiC)

Tuberculosis | Tuberculosis Infection

India
Daping Hospital and the Research Institute of Surgery...
The First Affiliated Hospital of Anhui Medical University; LanZhou University; Beijing 302 Hospital and other collaborators

Completed

A Trial Comparing Noninvasive Ventilation Strategies in Preterm Infants Following Extubation

Intubated Infants Were Intend to Extubation Using Noninvasive Ventilation Strategies

China
West China Hospital
Beijing Friendship Hospital; Obstetrics and Gynecology Hospital of Zhejiang... and other collaborators

Completed

Epidemiological Study of Iron Deficiency and Iron Deficiency Anemia in Chinese Pregnant Women (EIDACPW)

Anemia, Iron-Deficiency

China
University Hospital, Linkoeping
Rigshospitalet, Denmark; Sahlgrenska University Hospital, Sweden; Aalborg University... and other collaborators

Completed

Scandinavian Miller Collar Study (SCAMICOS)

Critical Limb Ischemia

Sweden
Ailin Luo
The First Affiliated Hospital of Anhui Medical University; The Affiliated Nanjing... and other collaborators

Recruiting

Esketamine on Postpartum Depression in Cesarean Section Women (EKET)

Postpartum Depression | Esketamine

China
Mahidol University
International Centre for Diarrhoeal Disease Research, Bangladesh; International... and other collaborators

Completed

Assessing Exclusive Breastfeeding Practice

Human Milk | Exclusive Breastfeeding | Breast Milk
China Academy of Chinese Medical Sciences
Peking University First Hospital; Peking Union Medical College Hospital; Chengdu... and other collaborators

Unknown

A Clinical Study on Qianjin Capsule of Gynaecology Combined With Antibiotics for Pelvic Inflammatory Diseases (Damp-heat Stasis and Qi Deficiency Syndrome)

Pelvic Inflammatory Diseases
Cancer Institute and Hospital, Chinese Academy...
Zhejiang Cancer Hospital; Peking Union Medical College Hospital; Henan Cancer... and other collaborators

Unknown

Study of Etoposide in Treating Patients With Recurrent or Metastatic Breast Cancer

Breast Cancer

China
Tongji Hospital
Zhejiang Cancer Hospital; Xiangya Hospital of Central South University; Beijing... and other collaborators

Not yet recruiting

Neoadjuvant Chemoimmunotherapy Versus Concurrent Chemoradiotherapy for LACC

Cervical Cancer | Locally Advanced Cervical Cancer | Concurrent Chemoradiotherapy | Neoadjuvant Chemoimmunotherapy

China
Shandong University
Qilu Hospital of Shandong University; The Affiliated Hospital of Qingdao University and other collaborators

Not yet recruiting

Bismuth-containing Quadruple Therapy for Helicobacter Pylori Eradication: A Randomized Clinical Trial of 10 and 14 Days

Helicobacter Pylori Infection

China
Tongji Hospital
Zhejiang Cancer Hospital; Xiangya Hospital of Central South University; Beijing... and other collaborators

Not yet recruiting

Neoadjuvant Immunochemotherapy in PD-L1-negative LACC

Cervical Cancer | Locally Advanced Cervical Cancer | PD-L1 Negative | Neoadjuvant Chemoimmunotherapy

China
First Affiliated Hospital of Guangxi Medical University
Second Affiliated Hospital of Guangzhou Medical University; LiuZhou People's... and other collaborators

Recruiting

PCP in Immunocompromised Population in Southern China (PCP)

Diagnosis | Polymerase Chain Reaction | Immunocompromised Patients | Pneumocystis Pneumonia

China
Harbin Medical University
The First Affiliated Hospital with Nanjing Medical University; Peking University... and other collaborators

Active, not recruiting

Safety and Efficacy of Drug-Coated Balloon for De-novo Lesions in Patients With Acute Coronary Syndromes (DCB-ACS) (DCB-ACS)

Coronary Artery Disease | De Novo Stenosis | Clinical Trial | Acute Coronary Syndromes | ACS | DCB | Drug-Coated Balloon

China
Zi-jiang Chen
The First Affiliated Hospital with Nanjing Medical University; LanZhou University and other collaborators

Unknown

Live Birth After Fresh Embryo Transfer Vs Frozen-thawed Embryo Transfer in Women With Polycystic Ovary Syndrome (FreFro-PCOS)

Polycystic Ovary Syndrome | Infertility

China
Peking Union Medical College Hospital
The First Affiliated Hospital with Nanjing Medical University; Peking University... and other collaborators

Recruiting

The Follow-up of Mesh/Native Tissue Complications Study(Part I)

Pelvic Floor

China
Peking Union Medical College Hospital
The First Affiliated Hospital with Nanjing Medical University; Peking University... and other collaborators

Recruiting

The Follow-up of Mesh/Native Tissue Complications Study(Part II)

Pelvic Organ Prolapse

China
Tongji Hospital
Zhejiang Cancer Hospital; Xiangya Hospital of Central South University; Beijing... and other collaborators

Not yet recruiting

Neoadjuvant Chemoimmunotherapy and Extrafascial Hysterectomy for IB2 Cervical Cancer

Cervical Cancer | Fertility Preservation | Radical Hysterectomy | Neoadjuvant Chemoimmunotherapy

China
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Early Check: Expanded Screening in Newborns

Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions

United States

Clinical Trials Sponsored by Shield Holdings

Sponsors and Collaborators

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Drug Interventions

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CROs in Angola

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