Clinical Trials Sponsored by Walton Centre NHS Foundation Trust

Total 3638 results

Manchester University NHS Foundation Trust
University of Manchester; National Institute for Health Research, United Kingdom

Active, not recruiting

Manchester Intermittent Diet in Gestational Diabetes Acceptability Study (MIDDAS-GDM)

Diabetes | Pregnancy Related | Gestational Diabetes | Gestational Diabetes Mellitus in Pregnancy | Intermittent Fasting | Diabetes in Pregnancy

United Kingdom
University of Cambridge
Cambridgeshire and Peterborough NHS Foundation Trust; Cambridge Cognition Ltd; Big Health Inc...

Completed

CBT to Reduce Insomnia and Improve Social Recovery in Early Psychosis (CRISP)

Psychotic Disorders | Sleep | Psychosis

United Kingdom
Norfolk and Norwich University Hospitals NHS Foundation...
University of East Anglia; Dynamic Metrics Ltd

Completed

Modelling and AI Using Sensor Data to Personalise REHABilitation Following Joint Replacement (MAPREHAB)

Arthroplasty Complications

United Kingdom
University Hospital Birmingham NHS Foundation Trust
University of Birmingham; Dystrophic Epidermolysis Bullosa Research Association...

Enrolling by invitation

Genotype-phenotype Correlation in Junctional Epidermolysis Bullosa

Junctional Epidermolysis Bullosa | Laryngo Onycho Cutaneous Syndrome

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
University of Exeter; NIHR Exeter Clinical Research Facility

Completed

The Genetics of Adipose Tissue Function and Its Link to Type 2 Diabetes and Heart Disease (FATFUNgenes)

Diabetes Mellitus

United Kingdom
University Hospitals of Derby and Burton NHS Foundation...
University of Nottingham; University of Birmingham

Withdrawn

A Feasibility Study of the SNUBY®, a Skin-to-skin Garment, in the Preterm Infant (Preterm SNUBY®)

Premature Birth | Breast Feeding
King's College London
Guy's and St Thomas' NHS Foundation Trust; University of Liverpool; Universidad...

Completed

Effects of Dietary Fibre in Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome

United Kingdom
Papworth Hospital NHS Foundation Trust
Roche Pharma AG; National Institute for Health Research, United Kingdom

Completed

A Therapeutic Open Label Study of Tocilizumab in the Treatment of Pulmonary Arterial Hypertension (TRANSFORM-UK)

Pulmonary Arterial Hypertension

United Kingdom
University Hospital Birmingham
Royal Free Hospital NHS Foundation Trust; University of Edinburgh; University...

Unknown

Comparing the Effects of Spironolactone With Chlortalidone on LV Mass in Patients With CKD (SPIRO-CKD)

Renal Insufficiency, Chronic | Cardio-Renal Syndrome

United Kingdom
Michael Reddington
National Institute for Health Research, United Kingdom

Completed

Physiotherapy for Sciatica; Is Earlier Better? (POLAR)

Low Back Pain | Sciatica | Radiculopathy
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; National Osteoporosis Society; Orthopaedic Research UK

Completed

The Effects of Obesity on Bone Structure and Strength

Obesity | Osteoporosis

United Kingdom
Thayyil, Sudhin
University College London Hospitals; Great Ormond Street Hospital for Children...

Completed

Magnetic Resonance Imaging Autopsy Study (MARIAS)

Sudden Infant Death | Stillbirths

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University Hospital, Angers; Imperial College London; Sheffield Hallam University

Completed

Subjective and Objective Methods of Assessing Walking Limitation Due to Claudication

Intermittent Claudication

United Kingdom
pSiMedica Limited
Singapore General Hospital; Guy's and St Thomas' NHS Foundation Trust; pSiOncology...

Unknown

32P BioSiliconTM in Addition to Gemcitabine in Pancreatic Cancer

Pancreatic Cancer

Singapore, United Kingdom
Imperial College London
Imperial College Healthcare NHS Trust; Experimental Cancer Medicine Centres

Recruiting

How Does Prostate Cancer Metastasize? Studying the Role of Secreted Packages (Exosomes) From Fat Tissue in Lean and Obese Patients (EXOPRO)

Obesity | Prostate Cancer

United Kingdom
St. Anna Kinderkrebsforschung
Centre Leon Berard; Medical University of Graz; Fondazione IRCCS Istituto Nazionale... and other collaborators

Unknown

Long Term Continuous Infusion ch14.18/CHO Plus s.c. Aldesleukin (IL-2) (LTI)

Neuroblastoma

France, Spain, Austria, Germany, Israel, Italy, United Kingdom
Liverpool John Moores University
University of Liverpool; Liverpool Heart and Chest Hospital NHS Foundation... and other collaborators

Recruiting

High-intensity Interval Training in Patients With Atrial Fibrillation (HIIT-AF)

Atrial Fibrillation

United Kingdom
University Hospital Birmingham NHS Foundation Trust
University of Birmingham; National Institute for Health Research, United Kingdom and other collaborators

Unknown

Can Vitamin D Supplementation in People With Crohn's Disease Improve Symptoms as an Adjunct Therapy? (D-CODE)

Vitamin D Deficiency | Crohn Disease

United Kingdom
St George's University Hospitals NHS Foundation...
University College, London; St George's, University of London; University of... and other collaborators

Recruiting

LFD of Aspergillus Antigen in Paediatrics (LFD-AsPaeds)

Invasive Pulmonary Aspergillosis | Invasive Fungal Disease

United Kingdom
University of Cambridge
Imperial College London; Cambridge University Hospitals NHS Foundation Trust; Wellcome Trust and other collaborators

Active, not recruiting

PET Imaging of Giant Cell and Takayasu Arteritis (PITA)

Giant Cell Arteritis | Takayasu Arteritis

United Kingdom
Imperial College London
University of Pennsylvania; University of Oxford; University of Edinburgh; Royal... and other collaborators

Completed

Single Dose of pGM169/GL67A in CF Patients

Cystic Fibrosis

United Kingdom
Sunnybrook Health Sciences Centre
Alzheimer's Drug Discovery Foundation; Weston Brain Institute

Recruiting

Nabilone for Agitation Blinded Intervention Trial (NAB-IT)

Alzheimer Disease | Agitation

Canada
Nottingham University Hospitals NHS Trust
University of Nottingham; Vertex Pharmaceuticals Incorporated; Cystic Fibrosis... and other collaborators

Completed

Gut Imaging for Function & Transit in Cystic Fibrosis Study 2 (GIFT-CF2)

Cystic Fibrosis

United Kingdom
King's College London
Guy's and St Thomas' NHS Foundation Trust; Institut Pasteur; The Leona M. and...

Active, not recruiting

The ADDapt Diet in Reducing Crohn's Disease Inflammation

Inflammatory Bowel Diseases | Crohn Disease

United Kingdom
Kingston University
National Institute for Health Research, United Kingdom; St George's University... and other collaborators

Recruiting

Non-medical Practitioner Workforce in the Urgent and Emergency Care System Skill-mix in England (SKILLmix-ED)

Emergencies

United Kingdom
Cardiff and Vale University Health Board
University College, London; University Hospital Birmingham NHS Foundation Trust and other collaborators

Completed

Patient Reported Outcome Measures for Ablation of Cardiac Arrhythmias

Cardiac Arrhythmia

United Kingdom
Milton S. Hershey Medical Center
Hospice Foundation of America; John and Wauna Harman Foundation

Completed

Using an End-of-life Conversation Game to Engage Underserved Communities in Advance Care Planning

Terminal Illness | Advance Care Planning | Advance Directives | Vulnerable Populations

United States
Sunnybrook Health Sciences Centre
Alzheimer's Drug Discovery Foundation; Weston Brain Institute

Recruiting

Telmisartan vs. Perindopril in Mild-Moderate Alzheimer's Disease Patients (SARTAN-AD)

Alzheimer's Disease

Canada
Shrewsbury and Telford Hospitals NHS Trust
The Shropshire and Mid Wales Fertility Centre

Recruiting

A Trial of Sperm Injection (PICSI) on Miscarriage Rates in Assisted Conception (PICSI)

Infertility | Miscarriage

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
JP Moulton Charitable Foundation; PRO.MED.CS Praha a.s.; Clinical Trials Research...

Completed

Trial of Ursodeoxycholic Acid (UDCA) for Parkinson's Disease: The "UP" Study

Parkinson's Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
CORDA, The Heart Charity; Apotex Inc.; The Cooley's Anemia Foundation,; The UK...

Unknown

Combined Chelation Treatment With Deferiprone and Deferoxamine in Thalassemia Major

Beta-Thalassemia

Italy
University College, London
M.D. Anderson Cancer Center; Mayo Clinic; Radboud University Medical Center; Sunnybrook... and other collaborators

Completed

PRostate Evaluation for Clinically Important Disease: Sampling Using Image-guidance Or Not? (PRECISION)

Prostate Neoplasm

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; National Institute for Health Research, United Kingdom

Recruiting

SDF for the Management of Dental Caries in Children in Primary Dental Care: Protocol for a Feasibility Study

Dental Caries in Children

United Kingdom
Manchester University NHS Foundation Trust
Roche Pharma AG; Imperial College London; University of Manchester; Unity Insights

Recruiting

Real-world Elecsys® GAAD Implementation and Validation to Improve Surveillance and Early Detection of HCC (REVISE-HCC)

Liver Cirrhosis | Hepatocellular Carcinoma

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
National Institute for Health Research, United Kingdom

Recruiting

Swallowing, Feeding and Eating in Children Born With Oesophageal Atresia/Trache-oesophageal Fistula (OA/TOF) (SaFE)

Esophageal Atresia With Tracheoesophageal Fistula

United Kingdom
Institute of Child Health
University College, London; Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Natural History Study of ATP1A3-related Disease

Alternating Hemiplegia of Childhood | ATP1A3-related Disease | Rapid Onset Dystonia Parkinsonism | CAPOS

United Kingdom
CCTU- Cancer Theme
AstraZeneca; Cancer Research UK; University of Cambridge

Recruiting

WIRE - Novel Treatments in Renal Cell Cancer (WIRE)

Renal Cell Cancer

United Kingdom
Queen Mary University of London
Barts & The London NHS Trust; Child Growth Foundation; The Patients Association

Active, not recruiting

Child Growth and Development in East London (CGDEL)

Growth Disorders | Child Development | Stunting | Stunted Growth

United Kingdom
Liverpool John Moores University
Liverpool University Hospitals NHS Foundation Trust; Royal Liverpool University... and other collaborators

Active, not recruiting

Can Brisk Walking Combined With Ingestion of a Lipid-lowering Drug Improve Fat Metabolism in Muscle?

Pre Diabetes

United Kingdom
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; National Institute for Health...

Completed

Intelligent Oxygen Therapy During Activities of Daily Living

Hypoxia | COPD | Hyperoxia

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
University of Oxford; National Institute for Health Research, United Kingdom

Completed

The POSA Trial - Positional Therapy for Positional OSA (POSA)

Sleep Apnea, Obstructive | Positional Sleep Apnea

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; National Institute for Health Research, United Kingdom

Completed

Selenium for Musculoskeletal Health

Osteoporosis

United Kingdom
Papworth Hospital NHS Foundation Trust
Innovate UK; Cambridge Respiratory Innovations Limited; Motor Neurone Disease... and other collaborators

Active, not recruiting

Validation Of Tidal/End -Tidal CO2 in ALS (VOTECO2ALS)

Motor Neuron Disease | Amyotrophic Lateral Sclerosis

United Kingdom
Karolinska University Hospital
University College London Hospitals; St. George's Hospital, London; Poole Hospital...

Completed

Pre-oxygenation With High-flow Nasal Cannula in Adults During Rapid Sequence Induction Anesthesia (PRIOR2)

Hypoxia | Surgery | Anesthesia | Acute

Sweden, Switzerland
Julie Dawson
University of East Anglia; GN Otometrics

Completed

Accuscreen Equipment Evaluation For Newborn Hearing Screening

Hearing Loss

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
University of Bristol; National Institute for Health Research, United Kingdom

Unknown

Mesothelioma and Radical Surgery 2 (MARS2)

Mesothelioma

United Kingdom
University of East Anglia
Norfolk and Norwich University Hospitals NHS Foundation Trust; British Medical...

Unknown

Nitrite in Hypertrophic Cardiomyopathy (HCM) Study

Cardiomyopathy, Hypertrophic

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
Novartis Pharmaceuticals; National Institute for Health Research, United Kingdom

Completed

The Vascular Effects of Vildagliptin in Insulin Resistant Individuals

Insulin Resistance | Microvascular Disease

United Kingdom
Birmingham Women's and Children's NHS Foundation...
University of Sheffield; Royal Manchester Children' s Hospital, Manchester

Completed

Whole Body Vibration Training in Children With Osteogenesis Imperfecta and Limited Mobility

Osteogenesis Imperfecta

United Kingdom
Jane Barnes
National Institute for Health Research, United Kingdom

Completed

Antiglucocorticoid Augmentation of antiDepressants in Depression (ADD)

Depression

United Kingdom

Clinical Trials Sponsored by Walton Centre NHS Foundation Trust

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