Clinical Trials Sponsored by SymbioPharm GmbH

Total 3283 results

Leipzig Heart Institute GmbH
Charite University, Berlin, Germany; University Hospital Schleswig-Holstein... and other collaborators

Unknown

SecOnd-generation seLf-expandable Versus Balloon-expandable Valves and gEneral Versus Local Anesthesia in TAVI (SOLVE-TAVI)

Aortic Stenosis

Germany
University of Latvia
Karolinska Institutet; Lithuanian University of Health Sciences; Technion, Israel... and other collaborators

Completed

Volatile Markers in Digestive Cancer (VOLGACORE)

Gastric Cancer | Colorectal Cancer | Colorectal Adenoma | Intestinal Metaplasia | Atrophic Gastritis | H.Pylori Infection | Peptic Ulcer Disease | Normal Control | Average-risk General Population

Latvia, Lithuania
James BOYD MD
Michael J. Fox Foundation for Parkinson's Research; Philipps University Marburg... and other collaborators

Unknown

Disease-modifying Potential of Transdermal NICotine in Early Parkinson's Disease (NIC-PD)

Parkinson's Disease

United States, Germany
Leipzig Heart Science gGmbH
Heart Center Leipzig - University Hospital; Zentrum für Klinische Studien Leipzig and other collaborators

Recruiting

Resuscitation Registry in CHD (PRO-CHD)

Cardiac Arrest | Congenital Heart Disease

Germany
Leibniz-Institut für Resilienzforschung (LIR) gGmbH
European Regional Development Fund; Ministry of Science and Health of Rhineland-Palatinate... and other collaborators

Recruiting

"resiLIR Healthcare Professionals": A Psychological Online Intervention to Enhance Resilience in Healthcare Professionals

Resilience

Germany
Leibniz-Institut für Resilienzforschung (LIR) gGmbH
European Regional Development Fund; Ministry of Science and Health of Rhineland-Palatinate... and other collaborators

Recruiting

"resiLIR Basic": A Psychological Online Intervention to Enhance Resilience in the General Population

Resilience

Germany
Kliniken Ludwigsburg-Bietigheim gGmbH
University Hospital, Essen; University of Leipzig; University Hospital Tuebingen and other collaborators

Unknown

Endoscopic Treatment of Non-variceal Upper GI-bleeding With High Risk of Recurrency - OTSC (Over-the-scope-clip) Versus Standard Therapy (STING2) (STING2)

Acute Upper Gastrointestinal Hemorrhage

Germany
Vivantes Netzwerk für Gesundheit GmbH
Medizinische Hochschule Brandenburg Theodor Fontane; Vivantes Klinikum am Urban and other collaborators

Active, not recruiting

Implementation, Efficacy and Costs of Inpatient Equivalent Home-Treatment in German Mental Health Care (AKtiV)

Personality Disorders | Anxiety Disorders | Addiction | Schizo Affective Disorder | Mental Disorder | Eating Disorders

Germany
Heidelberg University
German Federal Ministry of Education and Research; University of Ulm; Universitätsklinikum... and other collaborators

Completed

Comparison of a Group-delivered vs. Individually Delivered 'LiFE' Program (LiFE-is-LiFE)

Exercise | Fall Prevention

Germany
Heidelberg University
German Federal Ministry of Education and Research; University of Ulm; Universitätsklinikum... and other collaborators

Completed

Pilot of a Group-based Program on Lifestyle-integrated Functional Exercise (LiFE) in Older Persons

Physical Activity | Fall Prevention

Germany
Cardioangiologisches Centrum Bethanien
Goethe University; Ruhr University of Bochum; Technische Universität Dresden; University... and other collaborators

Completed

Reversal Agent Use in Patients Treated With Direct Oral Anticoagulants or Vitamin K Antagonists (RADOA)

Urgent Surgery | Severe Bleeding

Germany
Jacobs University Bremen gGmbH
Dr. Becker Hospital Group; Dr. Becker Klinik Möhnesee; Dr. Becker Burg-Klinik... and other collaborators

Completed

Feasibility and Benefits of Digital Services During the COVID19 Pandemic (AnhandCOV19)

Anxiety | Communication | Psychological Distress | Health Risk Behaviors | Healthy Lifestyle | Psychological Adjustment | Psychological Stress | Psychological Disorder | Behavior, Health | Psychological Disease | Psychosomatic Disorder | Psychological Adaptation | Health Care Seeking Behavior | Psychological Disability and other conditions

Germany
IRCCS Fondazione Stella Maris
University of Pisa; The University of Queensland; University of Castilla-La Mancha and other collaborators

Not yet recruiting

Validation of AI for Personalized Assessment and Rehabilitation of Upper Limb in Children With Unilateral Cerebral Palsy (AInCP)

Unilateral Cerebral Palsy

Italy, Spain
Australasian Gastro-Intestinal Trials Group
Bristol-Myers Squibb; Bayer; Syneos Health; University of Sydney; National Cancer... and other collaborators

Active, not recruiting

RegoNivo vs Standard of Care Chemotherapy in AGOC (INTEGRATEIIb)

Gastro-Oesophageal Cancer

Korea, Republic of, Australia, Taiwan, United States, Germany, Japan, Spain, Italy, Austria
Cystinose Stiftung
Labor Becker & Kollegen, Munich, Germany; Screening Labor Hannover; Genetikum... and other collaborators

Completed

Genetic Newborn Screening for Cystinosis and Spinal Muscular Atrophy (GENESIS1)

Spinal Muscular Atrophy | Cystinosis | Cystinosis, Nephropathic

Germany
Anne Birgitte Raben
University of Leeds; Wageningen University; University of Liverpool; Maastricht... and other collaborators

Completed

Sweeteners and Sweetness Enhancers: Prolonged Effects on Health, Obesity and Safety (SWEET)

Obesity

Spain, Denmark, Netherlands, Greece
Technical University of Munich
Rotkreuzklinikum München gGmbH; Klinikum Freising; Klinikum Landshut-Achdorf; Städtisches... and other collaborators

Completed

The Diagnostic Yield of Cap Assisted Upper Endoscopy in Esophagus (Kappa-III)

Endoscopic Diagnosis in Esophagus

Germany
Science Consulting in Diabetes
DexCom, Inc. a Delaware corporation, USA; Institut für Diabetes-Technologie...

Completed

Real-Time Continuous Glucose Monitoring (RT-CGM) in Patients With Type 1 Diabetes at High Risk for Low Glucose Values Using Multiple Daily Injections (MDI) in Germany (HYPODE-STUDY)

Diabetes

Germany
Hannover Medical School
University Hospital, Ghent; Johann Wolfgang Goethe University Hospital; University... and other collaborators

Unknown

Treatment of Adults Aged Up to 60 Years With De Novo Acute Myeloblastic Leukaemia,Secondary AML, or RAEB-T

De Novo Akute Myeloid Leukemia (AML) | Secondary Acute Myeloid Leukemia (AML) | Refractory Anemia With Excess of Blasts in Transformation

Germany
University Hospital Tuebingen
Coordination Centre for Clinical trials (KKS), 69120 Heidelberg, Germany; European... and other collaborators

Terminated

Penumbral Rescue by Normobaric O2 Administration in Patients With Ischemic Stroke and Target Mismatch ProFile (PROOF)

Acute Ischemic Stroke

Belgium, Germany, Finland, France, Spain
Stryker Trauma GmbH
St. Boniface Hospital; Fowler Kennedy Sport Medicine Clinic; Kelsey-Seybold Clinic and other collaborators

Completed

Use of Graft Jacket for Rotator Cuff Repair

Rotator Cuff Tear

Canada, United States
Prof Gerhard Walzl
London School of Hygiene and Tropical Medicine; Makerere University; Leiden University... and other collaborators

Completed

Evaluation of Host Biomarker-based Point-of-care Tests for Targeted Screening for Active TB (ScreenTB)

Pulmonary Tuberculosis

United Kingdom, Uganda, Ethiopia, Gambia, Germany, Namibia, Netherlands, South Africa
Amsterdam UMC, location VUmc
University Medical Center Groningen; Academisch Medisch Centrum - Universiteit... and other collaborators

Terminated

Cholinesterase Inhibitors to Slow Progression of Visual Hallucinations in Parkinson&Apos;s Disease (CHEVAL)

Parkinson's Disease

Netherlands
University of Warwick
King's College London; KU Leuven; University Hospital, Montpellier; Erasmus Medical... and other collaborators

Unknown

The MILESTONE Study: Improving Transition From Child to Adult Mental Health Care (MILESTONE)

Mental Health Disorder | Mental Health Impairment

Ireland, United Kingdom, Netherlands, Germany, Belgium, Croatia, France, Italy
Prof. Dr. Sonia Lippke
Dr. Becker Hospital Group; Dr. Becker Kiliani Clinic; Dr. Becker Clinic Möhnesee and other collaborators

Completed

ASAP - Assisted Immediate Augmented Post-/Long-COVID Plan for Patients Infected With COVID-19 (ASAP)

Psychological Distress | Healthy Lifestyle | Psychological Adjustment | Psychological Disorder | Psychological Disease | Long-COVID | Psychosomatic Disorder | Post-COVID | Psychological Impairment | Physiological Disease | Physiological Disorder | Physiological Impairment | Physiological Adjustment

Germany
Wuerzburg University Hospital
Helmholtz Zentrum München; Kassenärztliche Vereinigung Bayern; Klinikum Nürnberg and other collaborators

Active, not recruiting

Adipositas Care & Health Therapy (ACHT)

Obesity, Morbid | Patients After Metabolic-bariatric Surgery

Germany
New York Medical College
Washington University School of Medicine; University of California, Los Angeles and other collaborators

Active, not recruiting

Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease (HaploSCD)

Sickle Cell Disease

United States
Serum Institute of India Pvt. Ltd.
University of Stellenbosch; South African Tuberculosis Vaccine Initiative; Vakzine... and other collaborators

Completed

Study to Evaluate the Safety and Immunogenicity of VPM1002 in Comparison With BCG in HIV-exposed/-Unexposed Newborn Infants in South Africa

Tuberculosis

South Africa
London School of Hygiene and Tropical Medicine
Imperial College London; University of Sheffield; London School of Economics... and other collaborators

Unknown

TB Reduction Through ART and TB Screening Project (TREATS)

HIV/AIDS | Tuberculosis

South Africa, Zambia
Medisch Spectrum Twente
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; University of... and other collaborators

Recruiting

REal-time Data Monitoring for Shared Adaptive, Multi-domain and Personalised Prediction and Decision Making for Long-term Pulmonary Care Ecosystems (RE-SAMPLE) (RE-SAMPLE)

Pulmonary Disease, Chronic Obstructive | Comorbidities and Coexisting Conditions | Exacerbation Copd

Netherlands
University of Latvia
Uppsala University; Pontificia Universidad Catolica de Chile; Technion, Israel... and other collaborators

Recruiting

Screening of Gastric Cancer Via Breath Volatile Organic Compounds by Hybrid Sensing Approach (VOGAS)

Gastric Cancer | Gastric Dysplasia | Atrophic Gastritis | H.Pylori Infection

Brazil, Chile, Colombia, Latvia, Ukraine
Aalen University
DGUV (Deutsche Gesetzliche Unfallversicherung/German Social Accident Insurance... and other collaborators

Completed

Validation of Mesopic and Photopic Contrast Vision Tests With Respect to Nighttime Driving Ability (ContrastVal)

Cataract | Vision Disorders | Traffic Accident | Driving Impaired

Germany
Mukoviszidose Institut gGmbH
Hannover Medical School; Goethe University; Federal Ministry of Health, Germany; Wuerzburg University Hospital and other collaborators

Completed

Effects of a Comprehensive Patient-centered Health Service in Cystic Fibrosis (VEMSE-CF) (VEMSE-CF)

Cystic Fibrosis

Germany
Charite University, Berlin, Germany
Association of Statutory Health Insurance Physicians (KV Berlin); Statutory... and other collaborators

Active, not recruiting

PräVaNet - Structured, Intersectoral, Multiprofessional, Digitized Program to Optimize Cardiovascular Prevention (PräVaNet)

Arteriosclerosis | Type 2 Diabetes | Lipid Metabolism Disorders | Arterial Hypertension

Germany
Klinikum Rosenheim
Charite University, Berlin, Germany; Medtronic; University Hospital Tuebingen; Herz-Zentrums... and other collaborators

Unknown

CHOCO-CABANA Trial

Atherosclerosis

New Zealand, Austria, Germany
University of Oxford
King's College London; Bayer; Boston Children's Hospital; Queen Mary University... and other collaborators

Completed

Translational Research in Pelvic Pain (TRiPP)

Chronic Pain | Endometriosis | Bladder Pain Syndrome

United Kingdom, Portugal
Mats Heyman
Assistance Publique - Hôpitaux de Paris; Karolinska Institutet; Pfizer; The Swedish... and other collaborators

Recruiting

A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

Leukemia, Acute Lymphoblastic

Belgium, United Kingdom, Denmark, Germany, Portugal, Netherlands, Estonia, France, Finland, Iceland, Norway, Sweden, Lithuania, Ireland
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Unknown

Beta Testing of a New Assessment in Huntington's Disease (HD) (CAPIT-HD Beta)

Huntington Disease

France
Technical University of Munich
Paracelsus Medical University; Ludwig Boltzmann Institute for Digital Health... and other collaborators

Recruiting

Connect2Move: Valorization of Natural Cardio Trekking Hiking Trails (Connect2Move)

Healthy | Healthy Lifestyle | Cardiovascular Prevention

Germany
Universidade Nova de Lisboa
Hospital Santa Cruz, Centro Hospitalar de Lisboa Ocidental; Department of Neurology... and other collaborators

Completed

Shotgun Mass Spectrometry-based Lipid Profiling in Chronic Inflammatory Diseases

Cardiovascular Diseases | Inflammation | Healthy | Ischemic Stroke | Systemic Lupus Erythematosus | Biomarker | Lipid
University of Exeter
University of Oxford; Ludwig-Maximilians - University of Munich; Universitat... and other collaborators

Active, not recruiting

App-based Mental Health Promotion in Young European Adults (ECoWeB)

Wellbeing | Mental Disorder

Belgium, Germany, Spain, United Kingdom
Klinikum Oldenburg gGmbH
Deutsche Kinderkrebsstiftung; Gesellschaft fur Padiatrische Onkologie und Hamatologie... and other collaborators

Completed

Prospective Study of Children and Adolescents With Craniopharyngioma

Obesity | Craniopharyngioma

Germany
German Institute of Human Nutrition
Charite University, Berlin, Germany; University of Southern California; German... and other collaborators

Completed

NUtriGenomic Analysis in Twins (NUGAT)

Metabolic Response to Dietary Modification

Germany
Universitätsklinikum Hamburg-Eppendorf
Lithuanian University of Health Sciences; Örebro University, Sweden; University... and other collaborators

Recruiting

Proof of Concept Human Study: Dietary Intervention to Modify Intestinal Inflammation in IBD

Reduction of Intestinal Inflammatory Activity

Germany
Merck KGaA, Darmstadt, Germany
Merck Serono GmbH, Germany; Merck B.V., Netherlands; Merck A.E., Greece; Merck... and other collaborators

Completed

PERgoveriS In Stratified Treatment for Assisted Reproductive Technique (PERSIST)

Assisted Reproductive Techniques | Reproductive Technology, Assisted

Italy, Russian Federation, United Kingdom, Germany, Poland, Finland, Slovakia, Netherlands, Denmark, France, Greece
Universitätsklinikum Hamburg-Eppendorf
Hannover Medical School; Ludwig-Maximilians - University of Munich; Heidelberg... and other collaborators

Terminated

Neoadjuvant Treatment in Resectable Pancreatic Cancer (NEOPA)

Pancreatic Cancer

Germany
University of Medicine and Pharmacy Craiova
Odense University Hospital; University of Bergen; University College, London; University... and other collaborators

Completed

Contrast Enhanced Harmonic Endoscopic Ultrasound (CEH-EUS) in Focal Pancreatic Masses

Chronic Pancreatitis | Adenocarcinoma Pancreas

Denmark, France, Germany, Italy, Norway, Romania, Spain, United Kingdom
Charite University, Berlin, Germany
Ludwig-Maximilians - University of Munich; Technische Universität Berlin; BARMER and other collaborators

Completed

Enhanced Recovery After Intensive Care (ERIC)

Critical Illness

Germany
Professor Dr. Bernd Mühlbauer
Dept. of Statistics and Medical Biometry, University of Bremen; INSERM (Institut... and other collaborators

Unknown

An International Randomized Trial of Additional Treatments for COVID-19 in Hospitalized Patients Who Are All Receiving the Local Standard of Care - WHO-SOLIDARITY-GERMANY

COVID-19 | SARS-CoV-2 Infection | Moderate and Severe COVID-19

Germany
Michael Hoelscher
Karolinska Institutet; University of Stellenbosch; University of Cape Town Lung... and other collaborators

Completed

Rapid and Accurate Diagnosis of Paediatric TB (RaPaed-AIDA-TB) (RaPaed)

Tuberculosis | Diagnoses Disease

India, Mozambique, Tanzania, Malawi, South Africa

Clinical Trials Sponsored by SymbioPharm GmbH

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