Clinical Trials Sponsored by Acesion Pharma

Total 9066 results

Portola Pharmaceuticals

Completed

Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 1 of 4)

Healthy Volunteers

United States
AZ Delta
Alexion

Completed

Retrospective Chart Review Screening Algorithm to Assess the Prevalence of PNH-clones

Thrombosis | PNH

Belgium
Boston University
Actelion

Terminated

Macitentan in Pulmonary Hypertension of Sickle Cell Disease (MENSCH)

Sickle Cell Disease | Pulmonary Hypertension

United States
Ascension Genesys Hospital

Unknown

Oral Acetaminophen Use for Pain Reduction in Electrophysiology Procedures

Post Electrophysiology Procedure Pain

United States
Georgetown University
Actelion

Terminated

Placebo Controlled Trial of Bosentan in Scleroderma Patients

Systemic Scleroderma | Pulmonary Hypertension

United States
Aperion Biologics, Inc.

Unknown

Safety and Efficacy Study of the Z-Lig Medical Device Compared to Allograft (Z-Lig)

Ruptured Anterior Cruciate Ligaments

Italy, Belgium, Denmark, Netherlands, South Africa, Spain
UConn Health
Actelion

Terminated

Bosentan for Poorly Controlled Asthma

Asthma

United States
Ascension Genesys Hospital

Completed

The Use of the FAST (Focused Abdominal Scan for Trauma) Scan by Paramedics in Mass Casualty Incidents

Mass Casualty

United States
Ascension Genesys Hospital

Unknown

Study Comparing Patient Function and Satisfaction With Arthroscopic Subacromial Decompression Before and After Repair of Complete Rotator Cuff Tears

Rotator Cuff Tear | Acromial Spur

United States
Action, France

Unknown

Biological Collection and Registry of Patients Who Will Have a TAVR (Transcatheter Aortic Valve Replacement) Intervention (BIO TAVI)

Transcatheter Aortic Valve Replacement

France
Alexion Pharmaceuticals, Inc.

Not yet recruiting

Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular Hemolysis

Paroxysmal Nocturnal Hemoglobinuria | PNH | Extravascular Hemolysis
Alexion Pharmaceuticals, Inc.

Recruiting

Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN) (ICAN)

Immunoglobulin A Nephropathy | IgAN

Spain, United Kingdom, United States, Italy, Korea, Republic of, Belgium, Germany, Colombia, Japan, China, France, Saudi Arabia, Thailand, Australia, Canada, Brazil, Malaysia, Poland, Taiwan, Austria, Greece, Israel, Netherlands, Arge... and more
Alexion Pharmaceuticals, Inc.

Recruiting

Phase 3 Study of ALXN1850 in Pediatric Participants With HPP Previously Treated With Asfotase Alfa (CHESTNUT)

Hypophosphatasia

Australia, United States, Japan, Germany, Turkey, Italy, India, France, United Kingdom, Argentina, Canada
Alexion Pharmaceuticals, Inc.

Not yet recruiting

Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia (RESTORE)

Hypophosphatasia
Alexion Pharmaceuticals, Inc.

Recruiting

ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE (ARTEMIS)

Chronic Kidney Disease | CKD | Cardiopulmonary Bypass | Cardiac Disease

United States, China, United Kingdom, Germany, Italy, Korea, Republic of, Netherlands, Spain, Japan, Brazil, India, Taiwan, Australia, Canada, Israel, Hong Kong, Poland, Argentina, Turkey
Alexion Pharmaceuticals, Inc.

Recruiting

Evaluation of Pharmacokinetics, Pharmacodynamics, Efficacy, Safety, and Immunogenicity of Ravulizumab Administered Intravenously in Pediatric Participants With Generalized Myasthenia Gravis (gMG)

Generalized Myasthenia Gravis | gMG

Spain, Italy, United States, France, Switzerland, Serbia, Japan, Netherlands
Alexion Pharmaceuticals, Inc.

Recruiting

Safety, PK/PD, and Immunogenicity Study of SC ALXN2030 in Healthy Participants

Healthy

United Kingdom
Alexion Pharmaceuticals, Inc.

Recruiting

Efficacy and Safety Study of Ravulizumab IV in Pediatric Participants With NMOSD

Neuromyelitis Optica Spectrum Disorder

United States, Italy, Korea, Republic of, Japan, France, Germany, Spain, Canada
Alexion Pharmaceuticals, Inc.

Recruiting

Real Life Use of Ravulizumab in Italian Patients With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

Italy
Alexion Pharmaceuticals, Inc.

Recruiting

Study of ALXN2050 in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

Lupus Nephritis | Immunoglobulin A Nephropathy | IgAN | LN

Australia, Spain, United Kingdom, China, Germany, Italy, Argentina, Peru, Korea, Republic of, Taiwan, Thailand, United States, Serbia, Israel, Brazil, Turkey, Mexico, Russian Federation
Alexion Pharmaceuticals, Inc.

Recruiting

Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

Generalized Myasthenia Gravis

United States
Ascension Genesys Hospital

Recruiting

Efficacy of Local Anesthetic Through Continuous Infusion

Pain Control

United States
Alexion
Syneos Health

Recruiting

Atypical Hemolytic-Uremic Syndrome (aHUS) Registry

Atypical Hemolytic-Uremic Syndrome

France, Germany, Israel, Italy, United Kingdom, Canada, United States, Australia, Belgium, Denmark, Korea, Republic of, Poland, Russian Federation, Spain, Taiwan
Alexion Pharmaceuticals, Inc.

Completed

A Study to Investigate the Pharmacokinetic Profile of ALXN2050 Modified Release Prototype Formulations and Immediate Release Reference Tablet in Healthy Adult Participants

Healthy Participants

United Kingdom
Alexion Pharmaceuticals, Inc.

Terminated

Ravulizumab Versus Placebo in Adult Participants With Dermatomyositis

Dermatomyositis

Italy, Spain, United States, France, Germany, Korea, Republic of, United Kingdom, Poland, Japan
Alexion Pharmaceuticals, Inc.

Completed

Potential Drug Interaction Study Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel/Ethinyl Estradiol-containing Oral Contraceptives, and Carbamazepine

Healthy Participants

United States
Alexion Pharmaceuticals, Inc.

Enrolling by invitation

Registry of Patients With Hypophosphatasia

Hypophosphatasia (HPP)

United States, Italy, Russian Federation, Spain, United Kingdom, Germany, Canada, France, Saudi Arabia, Poland, Australia
Alexion Pharmaceuticals, Inc.

Completed

A Study to Investigate the Potential Drug Interactions Between ALXN2080 and Rosuvastatin and Metformin in Healthy Adult Participants

Healthy

United Kingdom
Alexion Pharmaceuticals, Inc.

Completed

Ravulizumab Subcutaneous (SC) Versus Ravulizumab Intravenous (IV) in Adults With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Eculizumab

Paroxysmal Nocturnal Hemoglobinuria

Italy, Spain, Belgium, France, Turkey, Austria, Brazil, Netherlands, Australia, Finland, Russian Federation, Sweden, Canada, United States
Alexion Pharmaceuticals, Inc.

Active, not recruiting

A Long-term Safety and Efficacy Study of Danicopan as an Add-on Therapy to Complement Component 5 Inhibitor (C5i) in Participants With PNH

Paroxysmal Nocturnal Hemoglobinuria

France, Italy, Spain, United States, Thailand, Korea, Republic of, United Kingdom, Israel, Czechia, Greece, Poland, Brazil, Japan, Canada, Malaysia
Alexion Pharmaceuticals, Inc.

No longer available

Expanded Access Program for Participants Who Completed Study 13-601 and Continue to Clinically Benefit From Cerdulatinib

Non-hodgkin's Lymphoma | Relapsed/Refractory Chronic Lymphocytic Leukemia
Ascension St. Vincent

Terminated

Discerning Pseudoprogression vs True Tumor Growth in GBMs

Glioblastoma
Alexion Pharmaceuticals, Inc.

Completed

Bioavailability Study of 2 Oral Formulations of ALXN1840

Healthy

Australia
Alexion Pharmaceuticals, Inc.

Terminated

Study of ALXN1840 Versus Standard of Care in Pediatric Participants With Wilson Disease

Wilson Disease

Spain, Korea, Republic of, France, Germany, Japan, Australia, Poland, United Kingdom
Alexion Pharmaceuticals, Inc.

Terminated

Ravulizumab in Thrombotic Microangiopathy Associated With a Trigger

Thrombotic Microangiopathy

United States, Belgium, France, Italy, Japan, Spain, Taiwan, United Kingdom, Canada, Korea, Republic of, Netherlands
Alexion Pharmaceuticals, Inc.

Available

Danicopan Early Access Program

Paroxysmal Nocturnal Hemoglobinuria | PNH | Extravascular Hemolysis
Alexion Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Safety and Tolerability of CAEL-101 in Patients With AL Amyloidosis

AL Amyloidosis

United States
Portola Pharmaceuticals

Terminated

Safety and Efficacy Study of Adjunctive Antiplatelet Therapy Prior to Primary PCI in Patients With STEMI (ERASE-MI)

Myocardial Infarction

United States, Canada
Portola Pharmaceuticals

Completed

A Study in Older Subjects to Evaluate the Safety and Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Apixaban

Bleeding

United States
Portola Pharmaceuticals

Completed

Acute Medically Ill VTE Prevention With Extended Duration Betrixaban Study (The APEX Study) (APEX)

Venous Thromboembolism (VTE)

Belgium, Israel, Italy, United States, France, Bulgaria, Australia, Germany, Russian Federation, Hungary, Singapore, Austria, Chile, Canada, United Kingdom, Czechia, Poland, Spain, Romania, Latvia, South Africa, Croatia, Serbia, Peru, U... and more
Portola Pharmaceuticals

Completed

Evaluate the Pharmacokinetics and Safety of MK-4448 in Participants With Nonvalvular Atrial Fibrillation or Atrial Flutter

Atrial Fibrillation | Atrial Flutter
Alexion Pharmaceuticals
Celerion

Completed

Study of the Metabolism of Danicopan in Healthy Adults

Healthy

United States
Ascension Genesys Hospital

Withdrawn

Intraoperative Dexamethasone and Its Effect on Hyperglycemia

Diabetes Mellitus

United States
Ascension Genesys Hospital

Completed

The Use of D5LR Versus LR for Induction of Labor and Time to Delivery in Multiparous and Primiparous Patient's With Favorable and Unfavorable Bishop's Scores

Induction of Labor Affected Fetus / Newborn

United States
Ascension Orthopedics, Inc.

Terminated

Ascension® Humeral Resurfacing Arthroplasty Follow-Up Study

Rheumatoid Arthritis Shoulder | Post-traumatic Arthrosis of Other Joints, Shoulder Region | Shoulder Arthritis Osteoarthritis | Acquired Deformity of Head

United States
Ascension Genesys Hospital

Unknown

Comparison of Patient Perceived Pain and Satisfaction Between Lightweight and Heavyweight Mesh for Laparoscopic Inguinal Hernia Repair

Inguinal Hernia

United States
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

Evaluation of Safety, Tolerability, and Antiviral Activity of ACH-0143102 Plus Ribavirin In Treatment-naive Hepatitis C Virus Infection Genotype 1b Participants

Chronic Hepatitis C Infection

United States
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

Study of Once Daily Elvucitabine Versus Lamivudine in Participants With a Documented M184V Mutation (Resistance)

HIV Infections

United States
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

A Long-Term Treatment Study of ACH-0144471 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria

New Zealand, Korea, Republic of, Italy
Alexion
Achillion, a wholly owned subsidiary of Alexion

Terminated

Safety and Antiviral Study of ACH126, 433 (b-L-Fd4C) in Adults With Lamivudine-resistant Chronic Hepatitis B

Chronic Hepatitis B

United States, Canada, China

Clinical Trials Sponsored by Acesion Pharma

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