Clinical Trials Sponsored by Heart Research U.K.

Total 1635 results

Baker Heart Research Institute
National Health and Medical Research Council, Australia

Unknown

The Neurobiology of Depressive Illness

Major Depression

Australia
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

Canadian Study of Arterial Inflammation in Patients With Diabetes and Vascular Events: EvaluatioN of Colchicine (CADENCE)

Cardiovascular Diseases | Inflammation | Diabetes | Atherosclerosis

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Rhythm Control - Catheter Ablation With or Without Anti-arrhythmic Drug Control of Maintaining Sinus Rhythm Versus Rate Control With Medical Therapy and/or Atrio-ventricular Junction Ablation and Pacemaker Treatment for Atrial Fibrillation (RAFT-AF)

Heart Failure | Atrial Fibrillation

Canada, Taiwan, Sweden, Brazil
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

A Pharmacodynamic Study of a Personalized Strategy for P2Y12 Inhibition Versus Ticagrelor in Reducing Ischemic and Bleeding Risk (RAPID MANAGE)

Acute Coronary Syndrome | Percutaneous Coronary Intervention

Canada
Baker Heart Research Institute
National Health and Medical Research Council, Australia

Unknown

Panic Disorder and Cardiac Risk

Panic Disorder

Australia
Cancer Research UK
Aleta BioTherapeutics

Recruiting

A Phase I/II Trial of ALETA-001 for the Treatment of Participants With B-cell Malignancies

Lymphoma, Follicular | Lymphoma, B-Cell | Lymphoma, Large B-Cell, Diffuse | Lymphoma, Non-Hodgkin | Lymphoma, Mantle-Cell

United Kingdom
Cancer Research UK
Latus Therapeutics

Terminated

A Trial Looking at the Use of Camostat in People Who Have Tested Positive for Coronavirus (COVID-19) (SPIKE-1) (SPIKE-1)

COVID-19 Infection

United Kingdom
Cardiff University
Cancer Research UK

Unknown

Trial to Test the Effects of Adding 1 of 2 New Treatment Agents to Commonly Used Chemotherapy Combinations (AML18)

Myelodysplastic Syndrome | Acute Myeloid Leukaemia

Denmark, United Kingdom
Cancer Research UK
Barinthus Biotherapeutics

Suspended

A Trial of ChAdOx1 and MVA Vaccines Against MAGE-A3 and NY-ESO-1

Esophageal Neoplasms | Non-small Cell Lung Cancer (NSCLC)

United Kingdom
Cancer Research UK
Bicycle Therapeutics

Completed

BT1718 in Patients With Advanced Solid Tumours.

Non-Small Cell Lung Cancer | Advanced Solid Tumours | Oesophageal Cancer | Non-Small Cell Lung Sarcoma

United Kingdom
Cancer Research UK
Oxford BioMedica

Completed

Effect of TroVax in Patients Having Colorectal Cancer With Liver Metastases Removed

Colorectal Neoplasms
National Heart Centre Singapore
Singapore Eye Research Institute

Not yet recruiting

JARVISDHL Screening Tools

Coronary Artery Disease

Singapore
Thiel, Alexander, M.D.
Ottawa Heart Institute Research Corporation

Recruiting

Contralesional Inhibitory rTMS for Recovery of Arm Function After Stroke (ConTRAstroke)

Feasibility Study

Canada
Ottawa Heart Institute Research Corporation
AFP Innovation Fund

Recruiting

Effect of a Hybrid Rehabilitation Program on Walking, Quality of Life & Cardiovascular Risk in People With PAD (HY-PAD)

Peripheral Arterial Disease

Canada
Ottawa Heart Institute Research Corporation
University of Calgary

Recruiting

Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance (TITAN:SvS)

Ascending Aorta Aneurysm | Ascending Aortic Aneurysm Enlargement

United States, Canada
Ottawa Heart Institute Research Corporation
Toronto General Hospital

Active, not recruiting

Early Post Transplant Cardiac Allograft Vasculopathy (ECAV)

Cardiac Allograft Vasculopathy

Canada
American Heart Association
Sanofi; Duke Clinical Research Institute

Active, not recruiting

Early Dronedarone Versus Usual Care to Improve Outcomes in Persons With Newly Diagnosed Atrial Fibrillation (CHANGE-AFIB)

Atrial Fibrillation

United States
Sakakibara Heart Institute
Japanese Foundation for Cancer Research

Completed

Pathogenic Mechanisms of Cancer and Cardiovascular Diseases

Cardiovascular Diseases | Cancer | Pathogenesis

Japan
Ottawa Heart Institute Research Corporation
Spartan Bioscience Inc.

Completed

ReAssessment of Anti-Platelet Therapy Using an InDividualized Strategy Based on GENetic Evaluation (RAPID GENE)

Acute Coronary Syndrome | Percutaneous Coronary Intervention | Stable Coronary Artery Disease

Canada
National Heart and Lung Institute
Nutricia Research Fundation

Completed

Enteral Nutrition in Congestive Heart Failure and Cardiac Cachexia

Chronic Heart Failure | Cardiac Cachexia

Poland, Germany
Dr. Anatoly Langer
Amgen

Active, not recruiting

GOAL International QuERI - Protocol CHRC 2019 GOAL INTERNATIONAL (GOAL QuERI)

Dyslipidemia

Kuwait, Mexico, Saudi Arabia, United Arab Emirates
AusculSciences Canada Inc.
Ottawa Heart Institute Research Corporation

Unknown

Evaluating Auscul-X, a Touch Free Digital Stethoscope

COVID-19

Canada
AusculSciences Canada Inc.
Ottawa Heart Institute Research Corporation

Unknown

A Novel Non-Invasive Acoustic Diagnostic for the Diagnosis of Coronary Artery Disease The CAD-det Validation Study

Cardiovascular Diseases | Coronary Artery Disease | Atherosclerosis | Coronary Occlusion

Canada
Ottawa Heart Institute Research Corporation
Jubilant DraxImage Inc.

Completed

Rubidium Elution System Performance Testing (REST-PET)

Coronary Artery Disease

Canada
Ottawa Heart Institute Research Corporation
University of Toronto

Withdrawn

Left Internal Thoracic Artery Bypass Versus Percutaneous Revascularization in Diabetics (LIBERTI)

Coronary Artery Disease | Diabetes Mellitus
Ottawa Heart Institute Research Corporation
The Ottawa Hospital

Terminated

Relation of Carotid Artery Plaque Inflammation, Covert Stroke and White Matter Disease

Stroke | Carotid Artery Stenosis | TIA

Canada
Ottawa Heart Institute Research Corporation
Spartan Bioscience Inc.

Completed

Pharmacogenetic Approach to Anti-platelet Therapy for the Treatment of ST-segment Elevation Myocardial Infarction (STEMI) (RAPID STEMI)

STEMI

Canada
Aspirus Heart and Vascular Institute-Research and...

Completed

Effect of Ranolazine on Arrhythmias and Microvolt T- Wave Alternans (MVTWA) Patients With LV Dysfunction

Sudden Cardiac Death | Ventricular Arrythmias

United States
Ottawa Heart Institute Research Corporation
The Change Foundation

Completed

Using Automated Calls To Improve Compliance With Acute Coronary Syndrome Best Practice Guidelines

Medication Adherence | Acute Coronary Syndrome

Canada
OrbusNeich
Duke Clinical Research Institute; OrbusNeich Medical K.K.

Completed

HARMONEE - Japan-USA Harmonized Assessment by Randomized, Multi-Center Study of OrbusNEich's Combo StEnt (HARMONEE)

Coronary Arteriosclerosis | Non ST Segment Elevation Acute Coronary Syndrome

United States, Japan
Wageningen University and Research
Fonterra (Europe) Cooperatie U.A.

Completed

Palatability and Perceived Satiety of Oral Nutrition Supplements

Sensory Evaluation | Perceived Satiety

Netherlands
U.S. Army Medical Research and Development Command
GlaxoSmithKline

Completed

A Phase I/II Trial of Tetravalent Live Attenuated Dengue Vaccine in Flavivirus Antibody Naive Infants

Dengue

Thailand
Pennington Biomedical Research Center
U.S. Army Medical Research and Development Command

Not yet recruiting

Military Health and Nutrition Examination Study (MHANES)

Cardiovascular Diseases | Hypertension | Dyslipidemias | Type 2 Diabetes

United States
U.S. Army Medical Research and Development Command
Naval Medical Research Center

Withdrawn

A Clinical Trial to Evaluate Plasmodium Falciparum 7G8 and NF54 Challenge Strains (PfSPZ) in a Head-to-head Comparative Study - (ECG-CHMI) (ECG-CHMI)

Plasmodium Falciparum
Huntington Medical Research Institutes
U.S. Army Medical Research and Development Command

Completed

Multimodal Approach to Testing the Acute Effects of Mild Traumatic Brain Injury (mTBI)

Concussion, Mild

United States
Naval Health Research Center
U.S. Army Medical Research and Development Command

Completed

Effectiveness of the Pneumococcal Polysaccharide Vaccine in Military Recruits

Pneumonia | Acute Respiratory Disease

United States
Kansas City Heart Rhythm Research Foundation
Kansas City Heart Rhythm Institute, Overland Park, KS

Recruiting

Efficacy Rate of Unipolar Polarity Switch for Lesion Assessment in Pulmonary Vein Isolation

Atrial Fibrillation

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI); Heart Failure Clinical Research...

Terminated

Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart Failure (SMMART-HF)

Heart Failure | Mitral Valve Insufficiency

United States, Canada
Macmillan Research Group UK
NMP Medical Research Institute

Completed

Impact of an Integrated Intervention on Mental Health in Survivors of Intimate Partner Violence

Domestic Violence

India
NMP Medical Research Institute
Macmillan Research Group UK

Completed

Enhancing Medical Compliance and Health-related Quality of Life of Patients With Epilepsy

Epilepsy
U.S. Army Medical Research and Development Command
GlaxoSmithKline

Completed

A Phase I/II Trial of a Tetravalent Live Attenuated DEN Vaccine in Flavivirus Antibody Naive Children

Dengue

Thailand
U.S. Army Medical Research and Development Command
GlaxoSmithKline

Completed

A Study of Two Doses of WRAIR Dengue Vaccine Administered Six Months Apart to Healthy Adults and Children

Dengue Fever | Dengue Hemorrhagic Fever | Dengue Shock Syndrome

Puerto Rico
U.S. Army Medical Research and Development Command
GlaxoSmithKline

Completed

A Phase II Trial of a Live Attenuated Virus Tetravalent Dengue Vaccine in Healthy Adults in Thailand

Dengue

Thailand
Hennepin Healthcare Research Institute
U.S. Department of Justice

Completed

Stress Biomarkers Among Patients Undergoing Treatment for Excited Delirium and Severe Pain in the Emergency Department (Agitation)

Pain | Agitation | Excited Delirium

United States
U.S. Army Medical Research and Development Command
GlaxoSmithKline

Completed

Safety and Preliminary Efficacy of the Malaria Vaccine Candidates Falciparum Merozoite Protein-1 (FMP1) and SmithKlineBeecham (SKBB) Candidate Malaria Vaccine RTS,S (MAL019)

Malaria, Falciparum

United States
U.S. Army Medical Research and Development Command
GlaxoSmithKline

Completed

A Phase I/II Trial of a Tetravalent Live Attenuated Dengue Vaccine in Flavivirus Antibody Naïve Children

Dengue Fever

Thailand
U.S. Army Medical Research and Development Command
GlaxoSmithKline

Terminated

Study to Evaluate the Efficacy and Safety of Tafenoquine for the Treatment of Plasmodium Vivax in Adults

Malaria | Plasmodium Vivax

Thailand
University College, London
Cancer Research UK; Cancer Research UK & UCL Cancer Trials Centre

Completed

Fludeoxyglucose F 18-PET/CT Imaging in Assessing Response to Chemotherapy in Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Hodgkin Lymphoma

Lymphoma

United Kingdom
Macmillan Research Group UK
NMP Medical Research Institute

Completed

Addition of Homeopathy in Patients With Resistant Arterial Hypertension

Hypertension, Resistant to Conventional Therapy

India
Kansas City Heart Rhythm Research Foundation
Montefiore Medical Center; Texas Cardiac Arrhythmia Research Foundation; Kansas... and other collaborators

Not yet recruiting

The ORCHESTRATE-Myocarditis Registry

Ischemia | Chest Pain | Myocarditis

United States

Clinical Trials Sponsored by Heart Research U.K.

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Venezuela

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations