Clinical Trials Sponsored by Luna Innovations

Total 6390 results

SCRI Development Innovations, LLC
Genentech, Inc.; Amgen

Completed

Combination Chemotherapy and Rituximab With Pegfilgrastim Followed by Rituximab, in Large B-Cell Non-Hodgkin's Lymphoma

Non-Hodgkins Lymphoma

United States
SCRI Development Innovations, LLC
Bristol-Myers Squibb

Completed

Ixabepilone and Cyclophosphamide as Neoadjuvant Therapy in HER-2 Negative Breast Cancer

Breast Cancer

United States
SCRI Development Innovations, LLC
Achieve Life Sciences

Completed

Phase II Trial of Carboplatin and Pemetrexed +/- OGX-427 in Untreated Stage IV Non-Squamous-Non-Small-Cell Lung Cancer (Spruce)

Non Squamous Non Small Cell Lung Cancer

United States
SCRI Development Innovations, LLC
Bristol-Myers Squibb

Completed

A Randomized Trial of Ixempra Versus Taxol in Adjuvant Therapy of Triple Negative Breast Cancer (TITAN)

Breast Cancer

United States, Puerto Rico
SCRI Development Innovations, LLC
Sanofi; GlaxoSmithKline; Novartis

Terminated

Cabazitaxel Plus Lapatinib as Therapy for HER2-Positive Metastatic Breast Cancer Patients With Intracranial Metastases

Metastatic Breast Cancer With Intracranial Metastases

United States
SCRI Development Innovations, LLC
GlaxoSmithKline; OSI Pharmaceuticals

Completed

Randomized, Double-Blind Trial of Erlotinib/Pazopanib or Erlotinib/Placebo in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer

Non Small Cell Lung Cancer

United States
SCRI Development Innovations, LLC
GlaxoSmithKline; Aventis Pharmaceuticals

Completed

Docetaxel, Vinorelbine and Trastuzumab in the Treatment of Patients With Metastatic Her-2 Positive Breast Cancer

Breast Cancer
MEI Pharma, Inc.
SCRI Development Innovations, LLC

Completed

Dose Escalation Study of the Safety and Pharmacokinetics of ME-344 Single Agent for Refractory Solid Tumors (ME-344-001)

Solid Tumors

United States
SCRI Development Innovations, LLC
Novartis; Genentech, Inc.

Completed

Bevacizumab (Avastin) and RAD001(Everolimus)in the Treatment of Advanced Clear Cell Renal Carcinoma

Kidney Cancer

United States
SCRI Development Innovations, LLC
AstraZeneca; Aventis Pharmaceuticals

Completed

Chemotherapy Plus Gefitinib Followed by Chemotherapy, Radiation Therapy, and Gefitinib For Head and Neck Cancer

Head and Neck Cancer

United States
Queen's University
AFP Innovation Fund

Recruiting

Structural Mitral Valve Project

Mitral Regurgitation

Canada
Interventional Cardiovascular Innovation Group,...

Not yet recruiting

Jordanian Coronary Artery Ectasia Registry (JoCAER)

Coronary Artery Ectasia
Jewish General Hospital
Exactis Innovation

Recruiting

TRIple Negative Breast Cancer Markers In Liquid Biopsies Using Artificial Intelligence (TRICIA)

Breast Cancer

Canada
Johnson & Johnson Enterprise Innovation Inc.

Active, not recruiting

Confocal Laser Endomicroscopy Nodule Localization by Robotic Bronchoscopy (CLEAR)

Lung Neoplasms

United States
GeNeuro Innovation SAS

Completed

Longitudinal Therapeutically Non-interventional Study of MSRV-Env Burden in Patients With Multiple Sclerosis Disease (LOMBARD)

Multiple Sclerosis (MS) | Clinically Isolated Syndrome (CIS) | Secondary Progressive MS | Primary Progressive MS | Relapsing-Remitting MS

France, Spain, Switzerland
GeNeuro Innovation SAS

Completed

Longitudinal Therapeutically Non-interventional Study of MSRV-Env Burden in Normal Population (CONTROL)

Multiple Sclerosis

France
GeNeuro Innovation SAS

Completed

First-in-Human Study With GNbAC1 in Healthy Volunteers

Multiple Sclerosis
GeNeuro Innovation SAS

Completed

Safety Study of GNbAC1 Monoclonal Antibody in Healthy Male Volunteers

Healthy Volunteers

Germany
The Orthopaedic Research & Innovation Foundation

Unknown

Retrospective Analysis on Distal Humerus Fractures ((DHFx))

Distal Humerus Fracture

United States
The Orthopaedic Research & Innovation Foundation

Unknown

Reverse Total Shoulder Arthroplasty: A Data Analysis on Patients Undergoing Reverse Total Shoulder Arthroplasty (rTSA)

Rotator Cuff Tear | Proximal Humeral Fracture | Osteo Arthritis Shoulders | Rotator Cuff Tear Arthropathy

United States
The Orthopaedic Research & Innovation Foundation

Active, not recruiting

Elbow Arthroscopy Data Analysis (EA)

Osteochondritis Dissecans | Lateral Epicondylitis, Left Elbow | Lateral Epicondylitis, Right Elbow | Osteoarthritis Elbow Left | Osteoarthritis Elbow Right | Plica Syndromes

United States
The Orthopaedic Research & Innovation Foundation

Active, not recruiting

Posterior Approach to Total Shoulder Arthroplasty (pTSA)

Osteo Arthritis Shoulders | Total Shoulder Arthroplasty

United States
University of Chicago
Innovations for Poverty Action

Recruiting

Testing Response Bias on Sensitive Topics in Self- Versus Enumerator-administered Surveys

Bias, Implicit

Colombia
Inovio Pharmaceuticals
Coalition for Epidemic Preparedness Innovations

Completed

Safety, Tolerability and Immunogenicity of INO-4700 for MERS-CoV in Healthy Volunteers

Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

Lebanon, Jordan, Kenya
SCRI Development Innovations, LLC
Bristol-Myers Squibb

Completed

Elotuzumab, Lenalidomide and Dexamethasone in Treatment of Transplant-Eligible Newly Diagnosed Multiple Myeloma Patients

Multiple Myeloma

United States
SCRI Development Innovations, LLC
Millennium Pharmaceuticals, Inc.

Completed

Orteronel as Monotherapy in Patients With Metastatic Breast Cancer (MBC) That Expresses the Androgen Receptor (AR)

Metastatic Breast Cancer

United States
SCRI Development Innovations, LLC
Bristol-Myers Squibb

Completed

Vinflunine in Hormone Refractory Prostate Cancer (HRPC)

Prostate Cancer

United States
SCRI Development Innovations, LLC
Novartis; Genentech, Inc.

Completed

RT, Temozolomide, and Bevacizumab Followed by Bevacizumab/Everolimus in First-line Treatment of GBM

Glioblastoma Multiforme

United States
SCRI Development Innovations, LLC
Novartis; Genentech, Inc.

Completed

RAD001 Plus Bevacizumab in Metastatic Melanoma

Metastatic Melanoma

United States
SCRI Development Innovations, LLC
AstraZeneca; Genentech, Inc.

Completed

Bevacizumab Given With Either Anastrozole or Fulvestrant With Trastuzumab for Postmenopausal Metastatic Breast Cancer

Breast Cancer | Breast Neoplasms

United States
SCRI Development Innovations, LLC
Millennium Pharmaceuticals, Inc.

Completed

Determining the Feasibility of MLN9708 as Maintenance After Allogeneic Stem Cell Transplant for Multiple Myeloma

Multiple Myeloma

United States
SCRI Development Innovations, LLC
GlaxoSmithKline; Novartis; Cephalon

Completed

Study of Bendamustine and Ofatumumab in Elderly Patients With Newly Diagnosed Diffuse Large B-Cell Lymphoma Who Are Poor Candidates for R-CHOP Chemotherapy

Diffuse Large B-Cell Lymphoma

United States
MEI Pharma, Inc.
SCRI Development Innovations, LLC

Terminated

ME-344 Given in Combination With Hycamtin® in Patients With Solid Tumors

Solid Tumors

United States, United Kingdom
SCRI Development Innovations, LLC
Infinity Pharmaceuticals, Inc.

Completed

Study of IPI-145 in Combination With Rituximab or Bendamustine/Rituximab in Hematologic Malignancies

Lymphoma | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | T-cell Lymphoma

United States
MEI Pharma, Inc.
SCRI Development Innovations, LLC

Completed

Phase I Dose Escalation Study of the Safety and Pharmacokinetics of ME-143 Single Agent for Refractory Solid Tumors

Solid Tumors

United States
SCRI Development Innovations, LLC
Bristol-Myers Squibb

Completed

Vinflunine in the Treatment of Patients With Relapsed Extensive Small Cell Lung Cancer

Lung Cancer | Carcinoma, Small Cell

United States
SCRI Development Innovations, LLC
GlaxoSmithKline; Genentech, Inc.

Completed

Topotecan in Combination With Docetaxel in Refractory and/or Advanced Solid Tumors

Cancer
SCRI Development Innovations, LLC
Acerta Pharma, LLC

Completed

Treatment With Acalabrutinib Post Blood or Marrow Transplantation in Subjects With Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
SCRI Development Innovations, LLC
Bristol-Myers Squibb

Completed

Bevacizumab and Cetuximab in Combination With FOLFOX6 in Patients With Metastatic Colorectal Cancer

Colon Cancer

United States
SCRI Development Innovations, LLC
Novartis; Genentech, Inc.

Terminated

Trial of the Combination of Bevacizumab and Everolimus in Patients With Refractory, Progressive Intracranial Meningioma

Intracranial Meningioma

United States
TG Therapeutics, Inc.
SCRI Development Innovations, LLC

Completed

Evaluate the Safety and Efficacy of TGR 1202 in Patients With Relapsed or Refractory Hematologic Malignancies

Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Chronic Lymphocytic Leukemia | Peripheral T-Cell Lymphoma

United States
Inovio Pharmaceuticals
Coalition for Epidemic Preparedness Innovations

Completed

Safety, Tolerability and Immunogenicity of INO-4500 in Healthy Volunteers

Lassa Fever

United States
TG Therapeutics, Inc.
SCRI Development Innovations, LLC

Completed

TGR-1202 Alone and in Combination With Either Nab-paclitaxel + Gemcitabine or With FOLFOX in Patients With Select Relapsed or Refractory Solid Tumors

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Rectal Cancer | Gastrointestinal Stromal Tumor (GIST)

United States
Aegis Medical Innovations
Applied Health Research Centre

Active, not recruiting

Feasibility Study of a Left Atrial Appendage Closure Device in Patients With Atrial Fibrillation (LASSO-AF)

Atrial Fibrillation

United States, Canada
SCRI Development Innovations, LLC
Achieve Life Sciences

Completed

Phase II Trial Of Gemcitabine Plus Nab-Paclitaxel +/- OGX-427 In Patients With Metastatic Pancreatic Cancer (Rainier)

Pancreatic Cancer

United States
SCRI Development Innovations, LLC
Daiichi Sankyo, Inc.

Completed

Phase I/II Trial of Tivantinib With FOLFOX for the Treatment of Advanced Solid Tumors and Previously Untreated Metastatic Adenocarcinoma of the Distal Esophagus, Gastroesophageal Junction or Stomach

Malignant Solid Tumour | Gastroesophageal Cancer

United States
SCRI Development Innovations, LLC
Novartis; Aventis Pharmaceuticals

Completed

Docetaxel Plus Imatinib Mesylate in Metastatic Breast Cancer

Breast Cancer

United States
Gayle Gordillo
Vomaris Innovations

Completed

Procellera and Negative Pressure Therapy for Acute Wounds

Wound

United States
SCRI Development Innovations, LLC
Bayer; OSI Pharmaceuticals

Completed

Sorafenib and Erlotinib or Sorafenib Alone in Advanced Non-Small Cell Lung Cancer Progressing on Erlotinib

Non-Small Cell Lung Cancer

United States
SCRI Development Innovations, LLC
Sanofi; Genentech, Inc.

Completed

Carboplatin, Docetaxel, Bevacizumab, and Erlotinib Versus Chemotherapy Alone in Resected NSCLC

Non-Small Cell Lung Cancer

United States

Clinical Trials Sponsored by Luna Innovations

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