Clinical Trials Sponsored by Motif Bio

Total 2362 results

Bio-Thera Solutions

Terminated

Assessment of Safety and Preliminary Efficacy With BAT6021 in Solid Tumor Patients in China

Solid Tumor

China
Provention Bio, Inc.

Completed

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of PRV-3279 in Healthy Subjects (PREVAIL1)

Safety

United States
ReNetX Bio, Inc.

Completed

AXER-204 in Participants With Chronic Spinal Cord Injury (RESET)

Chronic Spinal Cord Injury

United States
Bio 54, LLC

Completed

Treatment of Post-Punch Biopsy Bleeding in Anticoagulated Patients Using Self-Administered BXP154

Wound Bleeding

United States
Bio-Thera Solutions

Completed

Comparative Study of BAT2206 With Stelara® in Patients With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

China
Nuvation Bio Inc.

Withdrawn

Study of NUV-422 in Combination With Fulvestrant in Patients With HR+HER2- aBC

Breast Cancer | Advanced Breast Cancer | Metastatic Breast Cancer | Breast Carcinoma | Cancer of Breast | Malignant Tumor of Breast | Breast Tumor | Cancer of the Breast

United States
Upstream Bio Inc.

Completed

Safety and Blood Levels After a Single Injection of UPB-101 in Healthy Japanese and Non-Japanese Non-East Asian Adults

Healthy

United Kingdom
Bio-Thera Solutions

Terminated

Assessment of Safety and Preliminary Efficacy With BAT6026 in Solid Tumour Patients

Advanced Solid Tumour

Australia
Qlaris Bio, Inc.

Completed

Safety and Tolerability Study of QLS-101 in Adolescents With Sturge-Weber Syndrome (SWS)-Related Glaucoma Due to Elevated Episcleral Venous Pressure (EVP)

Ocular Hypertension | Glaucoma | Sturge-Weber Syndrome

United States
Qlaris Bio, Inc.

Completed

Study to Evaluate QLS-101 Compared to Timolol Maleate Eye Drops in Subjects With High Eye Pressure (Glaucoma or Ocular Hypertension).

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Bio-Thera Solutions

Completed

A Phase I Clinical Trial of BAT4306F on Safety, Tolerability and Pharmacokinetics for Patients

Non-Hodgkin's Lymphoma

China
AmMax Bio, Inc.

Withdrawn

A Phase 2 Study to Evaluate Safety and Efficacy of AMB-05X in Subjects With Idiopathic Pulmonary Fibrosis

IPF
CKD Bio Corporation

Completed

Safety and Efficacy of CKDB-501A in Subjects With Moderate-to-severe Glabellar Lines

Glabellar Lines

Korea, Republic of
Goldfinch Bio, Inc.

Terminated

An Open-Label, Long-term Study of GFB-887 in Patients With Glomerular Kidney Diseases

Kidney Diseases | Glomerulonephritis | Nephritis | Nephrosis | Glomerulosclerosis | Focal Segmental Nephrosis | Lipoid Urologic Disease

United States
Goldfinch Bio, Inc.

Terminated

A Study of TRPC5 Channel Inhibitor in Patients With Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, and Treatment-Resistant Minimal Change Disease

Kidney Diseases | Urologic Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Complications | Diabetic Nephropathies | Glomerulonephritis | Nephritis | Glomerulosclerosis, Focal Segmental | Nephrosis | Nephrosis, Lipoid

United States
Bio-Thera Solutions

Completed

Evaluate the Pharmacokinetics of BAT2022 in Healthy Chinese Subjects

SARS-CoV-2 Infection

China
Gritstone bio, Inc.

Completed

A Screening Study Targeting Tumor-specific Antigens

Metastatic Colorectal Cancer | Stage II/III Colon Cancer

United States
L&C Bio

Active, not recruiting

Clinical Trial to Evaluate the Efficacy and Safety of MegaCarti® in Knee Cartilage Defects

Osteoarthritis, Knee

Korea, Republic of
ExeVir Bio BV

Terminated

Dose-Finding, Safety, and Efficacy Study of XVR011 Added to Standard of Care in Patients Hospitalised for COVID-19

Covid19

Italy, Belgium, Moldova, Republic of
Goldfinch Bio, Inc.

Completed

First-In-Human Study of GFB-024 in Healthy Overweight and Obese Participants, and Participants With Type 2 Diabetes

Kidney Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Complications | Diabetic Nephropathies

United States
Epirium Bio Inc.

Completed

Safety and Biomarker Response to (+)-Epicatechin in Becker Muscular Dystrophy

Becker Muscular Dystrophy

United States
Inmune Bio, Inc.

Terminated

INB03 for the Treatment of Pulmonary Complications From COVID-19

COVID-19

United States
PT Bio Farma

Completed

Immunogenicity and Safety of Vi-DT (Diphtheria Toxoid) Typhoid Conjugate Vaccine (Phase III)

Safety Issues | Immunogenicity

Indonesia
Versanis Bio, Inc.

Completed

Variability of Physical Assessments in an Older Population That is Overweight or Obese

Obesity | Aging

United States
Bio-Thera Solutions

Completed

Comparative Study to Evaluate the Pharmacokinetics of BAT1806 vs Actemra® in Healthy Subjects

Rheumatoid Arthritis

China
Bio Products Laboratory

Completed

Registry Study of COAGADEX® Patients With Moderate or Severe Hereditary Factor X Deficiency Undergoing Major Surgery

Factor 10 Deficiency

United States
Tetra Bio-Pharma

Unknown

Safety and Efficacy of Inhaled Cannabis For the Uncontrolled Pain Relief in Patients With Advanced Cancer (PLENITUDE)

Quality of Life | Pain, Acute | Cannabis Use | Cancer Pain

United States
Bio-Thera Solutions

Withdrawn

A Phase 1/2 Study to Assess Safety and Efficacy of BAT2020 in Hospitalized COVID-19 Patients

COVID-19

United States
Bio Products Laboratory

Terminated

Post-Marketing Safety Study Following Long-Term Prophylactic OptivateTreatment in Subjects With Severe Haemophilia A

Haemophilia A

Colombia, Germany, Poland
Entera Bio Ltd.

Completed

A Six-month Phase 2 Study of Oral hPTH(1-34) (EBP05) in Postmenopausal Women With Low Bone Mass

Osteoporosis

Israel
Belite Bio, Inc

Completed

Safety and Tolerability of Escalating Doses of BPN-14967 in Healthy Adults

Healthy Volunteers

United States
J Ints Bio

Withdrawn

Heat Shock Protein Inhibitor- MPT0B640 for COVID-19 Infection

Covid19
Atox Bio Ltd

Completed

AB103 Peptide Antagonist in Healthy Volunteers

Healthy Volunteer Safety Study

United States
Tetra Bio-Pharma

Suspended

Safety and Efficacy of Inhaled Synthetic THC/CBD for Improving Physical Functioning and for Modulating Cachexia Progression in Patients With Advanced Cancer and Associated Cachexia (SERENITY)

Advanced Cancer | Cannabis Use | Cachexia; Cancer

Canada
Bio Sidus SA

Unknown

Study of HEMAX PFS Versus EPREX/ ERYPO® in Predialysis Chronic Kidney Disease

Anemia of Chronic Kidney Disease

Argentina, Paraguay
CTC Bio, Inc.

Completed

A Clinical Trial to Compare Pharmacokinetics of the "CDFF0318" and "Champix Tab. 1mg"

Smoking Cessation | Pharmacokinetics

Korea, Republic of
Fundatia Bio-Forum

Completed

Efficacy of a Spirulina Supplement for Amelioration of Benign ThYroid Nodules (ESSAY)

Benign Thyroid Nodule

Romania
Sesen Bio, Inc.

Completed

Study of Vicinium for Treating Patients With Non-Invasive Urothelial Carcinoma In Situ

Urinary Bladder Cancer | Bladder Cancer | Bladder Neoplasms | Bladder Tumors

United States, Canada
Tetra Bio-Pharma

Completed

Safety and Pharmacokinetics of Smoked Cannabis in Healthy Patients

Healthy Volunteers

Canada
Bio-Thera Solutions

Unknown

A Clinical Trial of BAT8001 on Safety, Tolerability and Pharmacokinetics for Patients

HER2-Positive Solid Tumors

China
Bio-Thera Solutions

Completed

A Phase III Study Evaluate the Efficacy and Safety of BAT1406 and Humira

Ankylosing Spondylitis
Tetra Bio-Pharma

Terminated

Safety and Efficacy of Smoked Cannabis for Improving Quality of Life in Advanced Cancer Patients

Cancer | Chronic Pain Due to Malignancy (Finding)

Canada
Lexent Bio, Inc.

Terminated

Detection of Tumor DNA in Blood Samples From Patients With Early Stage Cancer and "Healthy Controls"

Neoplasms, Non-hematologic - Stage I-III

United States
Takara Bio Inc.

Completed

Study of HF10 in Patients With Refractory Head and Neck Cancer or Solid Tumors With Cutaneous and/or Superficial Lesions

Malignant Melanoma | Carcinoma of the Breast | Squamous Cell Carcinoma, Skin | Refractory Head and Neck Cancer

United States
Bio Products Laboratory

Terminated

Safety & Efficacy of BPL's High Purity FACTOR X in Treatment of Factor X Deficient Subjects Undergoing Surgery (Ten03)

Factor X Deficiency

United Kingdom, United States, Spain, Turkey
Fundatia Bio-Forum

Completed

Post-Stroke Improvement of Motor Function (PSIOM)

Cerebrovascular Accident

Romania
Bio Products Laboratory

Completed

An Open Study to Investigate the Safety and Efficacy of Replenine®-VF in Severe Haemophilia B Patients

Haemophilia B

United Kingdom, Poland
Bio Products Laboratory

Completed

An Open-study to Investigate the Safety and Efficacy of Replenine®-VF in Haemophilia B Subjects Undergoing Surgery

Haemophilia B

Poland, Romania, Russian Federation
Bio Products Laboratory

Completed

A Study of the Safety and Efficacy of Vigam® Liquid in Patients With Primary or Secondary Antibody Deficiency

Primary or Secondary Antibody Deficiency

United Kingdom
Bio Products Laboratory

Completed

A Study to Compare the Pharmacokinetics and Safety of Current Factor VIII Concentrate and Optivate® in Haemophilia A.

Von Willebrand Disease

Poland, United Kingdom

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