Clinical Trials Sponsored by Singula Institute

Total 75083 results

Institut de Cancérologie de la Loire
National Cancer Institute, France

Unknown

I2S-Health Prevention (I2S)

Secondary School Student in General High School Who Does Not Have a Disability That Does Not Allow a Good Understanding of the Study Requirements

United States, France
Roswell Park Cancer Institute
National Cancer Institute (NCI); National Institutes of Health (NIH); University...

Recruiting

Effect of E-Liquid Flavor on Respiratory Symptoms in People Using Electronic Nicotine Delivery Systems (CRoFT)

Electronic Cigarette Use

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI); AstraZeneca; Genentech, Inc.; National Institutes...

Active, not recruiting

Acalabrutinib, Venetoclax, and Obinutuzumab for Initial Therapy of CLL (AVO)

Chronic Lymphocytic Leukemia (CLL)

United States
Karolinska Institutet
Norwegian Institute of Public Health; Finnish Institute for Health and Welfare and other collaborators

Completed

Tobacco Use and the Risk of COVID-19

Covid19
Jennifer Bramen
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

mSIM: Mobile Simultaneous Aerobic Exercise and Memory Training Intervention for Amnestic Mild Cognitive Impairment (mSIM)

Amnestic Mild Cognitive Impairment

United States
Institut Claudius Regaud
West Cancerology Institute, France; Toulouse Capitole University

Recruiting

Anthropological, Socio-cultural and Psychological Surgeons' Factors in Oncology and Brakes for Evaluation of Innovations (SURGprofil)

Surgery

France
Institut Pasteur
National Institute of Hygiene and Epidemiology - Vietnam (NIHE)

Completed

MOVIDA 1 Ter - Evaluation of the Cobas® Plasma Separation Card in the Field in Vietnam (MOVIDA1-Ter)

HIV Infections

Vietnam
Karolinska Institutet
Umeå University; Eastman Dental Insitute and Hospital

Recruiting

Regenerative Treatment of Traumatized Immature Permanent Incisors With Pulp Necrosis

Regenerative Endodontics in Traumatized Immature Teeth

Sweden
Istituto Giannina Gaslini
Bambino Gesù Hospital and Research Institute

Terminated

Efficacy of Anti-CD20 Antibodies (Rituximab Biosimilar) in the Treatment of Childhood Steroid-dependent Nephrotic Syndrome

Nephrotic Syndrome Steroid-Dependent

Italy
Cancer Prevention and Research Institute, Italy
Istituto Toscano Tumori

Unknown

Self Collected Sampling in Non-attendees Cervical Cancer Screening: DNA Test and Molecular Triage for HPV Positive Women

Cervical Cancer

Italy
Italian Institute of Telemedicine
Istituto Auxologico Italiano; Bracco Corporate

Completed

Blood Pressure Control and Compliance to Treatment in Hypertensive Patients With Metabolic Syndrome: a Study Based on Home Blood Pressure Telemonitoring and Assessment of Psychological Determinants (TELEBPMET)

Metabolic Syndrome | Arterial Hypertension

Italy
Istituto Scientifico H. San Raffaele

Unknown

Hydroxyurea With or Without Imatinib Mesylate in Treating Patients With Recurrent or Progressive Meningioma

Brain and Central Nervous System Tumors

Italy
Istituto Scientifico H. San Raffaele

Unknown

Study of Blood and Tissue Samples in Predicting Response to Second-Line Therapy Using Erlotinib Hydrochloride or Chemotherapy in Patients With Advanced Non-Small Cell Lung Cancer

Lung Cancer

Italy
Children's National Research Institute
National Institute of Nursing Research (NINR); National Institutes of Health... and other collaborators

Active, not recruiting

FACE for Children With Rare Diseases (FACE-Rare)

Rare Diseases

United States
OHSU Knight Cancer Institute
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes...

Terminated

Imaging of Intravenous (IV) Combidex to Brain, Intra-cerebral Tumors and in Central Nervous System (CNS) Inflammation

Brain Neoplasms

United States
National Cancer Institute (NCI)
Finnish Institute for Health and Welfare

Completed

Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study

Stroke | Diabetes Mellitus | Cancer | Heart Disease

Finland
National Eye Institute (NEI)
National Human Genome Research Institute (NHGRI)

Completed

Nitisinone for Type 1B Oculocutaneous Albinism

Albinism | Vision Loss

United States
OHSU Knight Cancer Institute
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes...

Terminated

Neurotoxicity in Primary Central Nervous System Lymphoma (PCNSL): An International Observational Study of Cognition in Long Term Survivors

Primary Central Nervous System Lymphoma (PCNSL)

United States, Germany
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Vaccine Therapy, Tretinoin, and Cyclophosphamide in Treating Patients With Metastatic Lung Cancer

Lung Cancer

United States
Istituto Giannina Gaslini
Bambino Gesù Hospital and Research Institute

Recruiting

Rituximab Versus Mycophenolate Mofetil in Children With Steroid-dependent Idiopathic Nephrotic Syndrome. (RTXvsMMF)

Nephrotic Syndrome Steroid-Dependent

Italy
Duke University
National Eye Institute (NEI); National Institutes of Health (NIH)

Not yet recruiting

Peripheral Retina Robotically Aligned OCT Study (PR-RAOCT)

Retinal Disease

United States
National Cancer Institute (NCI)

Not yet recruiting

A Phase II Study Evaluating an Organ Preservation Strategy Using Immune Checkpoint Blockade for Participants With Primary Colorectal or Gastroesophageal Cancer

Colorectal Cancer | Gastroesophageal Cancer

United States
National Cancer Institute (NCI)

Recruiting

Natural History Study of Kaposi Sarcoma

HIV | Kaposi Sarcoma

United States
National Cancer Institute (NCI)

Not yet recruiting

Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

Glioma | Astrocytoma | Recurrent Glioblastoma

United States
National Cancer Institute (NCI)

Recruiting

Lurbinectedin With or Without Avelumab in Small Cell Carcinoma of the Bladder (LASER)

Small Cell Carcinoma of the Bladder | High Grade Neuroendocrine Tumors of the Urinary Tract

United States
National Cancer Institute (NCI)

Recruiting

Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base Tumors

Locally Advanced Chondrosarcoma | Metastatic Chondrosarcoma | Metastatic Sinonasal Adenocarcinoma | Locally Advanced Sinonasal Adenocarcinoma | Metastatic Large-cell Neuroendocrine Carcinoma | Locally Advanced Large-cell Neuroendocrine Carcinoma | Metastatic Olfactory Neuroblastoma | Locally Advanced... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

Glioma | Ependymoma | Medulloblastoma

United States
National Cancer Institute (NCI)

Not yet recruiting

Erlotinib in Combination With Select Tyrosine Kinase Inhibitors in Adult Patients With Advanced Solid Tumors

Neoplasms

United States
National Cancer Institute (NCI)

Recruiting

18F-Fluciclovine PET/CT in Multiple Myeloma

Multiple Myeloma | Relapsed and/or Refractory Multiple Myeloma (RRMM) | Newly Diagnosed Multiple Myeloma (NDMM)

United States
National Cancer Institute (NCI)

Recruiting

Enzalutamide and M9241 in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering Therapy

Recurrent Prostate Cancer | Prostate Cancer | PET Positive

United States
National Cancer Institute (NCI)

Not yet recruiting

Phase II Study of Pacritinib in Kaposi Sarcoma Herpesvirus (KSHV)-Associated Multicentric Castleman Disease and KSHV-Associated Inflammatory Cytokine Syndrome (KICS)

KSHV Inflammatory Cytokine Syndrome (KICS) | Kaposi Sarcoma Herpesvirus -Associated Multicentric Castleman Disease

United States
National Cancer Institute (NCI)

Recruiting

Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors and Carcinomas

Neuroendocrine Tumors | Carcinoma, Neuroendocrine | Neuroendocrine Carcinomas | Carcinoma, Adrenal Cortical | Carcinoma, Adrenocortical

United States
National Cancer Institute (NCI)

Recruiting

Pilot Prospective Study for PET-CT Imaging in Participants With Relapsed/Refractory Acute Leukemias

Acute Lymphoblastic Leukemia | Relapsed/Refractory | B Cell

United States
National Cancer Institute (NCI)

Recruiting

Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma

Mesothelioma | BRCA1-Associated Protein-1 (BAP1) Mutations | Malignant Mesothelioma (MM) | Early-stage Mesothelioma | Subclinical Mesothelioma | Early-stage BAP1-associated Malignancies

United States
National Cancer Institute (NCI)

Recruiting

Eltanexor (KPT-8602) With Inqovi (Decitabine-Cedazuridine) in High-Risk Myelodysplastic Syndromes

Myelodysplastic Syndromes

United States
National Cancer Institute (NCI)

Recruiting

Phase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG With Entinostat and Nivolumab as Adjuvant Therapy Following Chemoradiation Therapy With or Without Surgery for Locally Advanced Esophageal Cancer

Neoplasms | Esophageal Neoplasms | Esophagus Cancer | Esophagus Neoplasm | Neoplasms, Esophageal | Esophageal Cancer (EsC)

United States
National Cancer Institute (NCI)

Recruiting

Study of Rates of Prostate Cancer Diagnosis in Men of African Ancestry Using MRI and MRI Guided Biopsy

Prostatic Neoplasms | Prostate Specific Antigens | Positive Digital Rectal Examination | Strong Family History of Prostate Cancer

United States
National Cancer Institute (NCI)

Recruiting

Trial of Anti-CD19 and Anti-CD20 Bicistronic Chimeric Antigen Receptor T Cells for Treating B-Cell Malignancies

Lymphoma, B-Cell | Chronic Lymphocytic Leukemia | B-Cell Chronic Lymphocytic Leukemia

United States
National Cancer Institute (NCI)

Recruiting

Study of Aerosolized Antibiotics and Pembrolizumab in Advanced Non-small Cell Lung Cancer

Advanced Non Small Cell Lung Cancer

United States
National Cancer Institute (NCI)

Recruiting

Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung | Non-Small Cell Lung Cancer | Non-Small Cell Lung Carcinoma | Carcinomas

United States
National Cancer Institute (NCI)

Recruiting

Prospective Monitoring of Subjects With Biochemically Recurrent Prostate Cancer Using 18FDCFPyL

Prostate Cancer | Biochemically Recurrent

United States
National Cancer Institute (NCI)

Recruiting

Study of Zotiraciclib for Recurrent High-Grade Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

Cancer | Brain Tumor

United States
National Cancer Institute (NCI)

Recruiting

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation | Peripheral Blood Stem Cell Transplantation

United States
National Cancer Institute (NCI)

Recruiting

Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral Microdialysis

Glioma

United States
National Cancer Institute (NCI)

Recruiting

Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas

Burkitt Lymphoma | Plasmablastic Lymphoma | Non-Hodgkin Lymphoma | Diffuse Large Cell Lymphoma | B-Cell Neoplasm

United States
National Cancer Institute (NCI)

Recruiting

Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial

Neurofibromatosis 1 | Noonan Syndrome | Legius Syndrome | Cardiofaciocutaneous Syndrome | Costello Syndrome

United States
National Cancer Institute (NCI)

Recruiting

Rare Tumors and Cancer Predisposition in Individuals and Families

Cancer | Hereditary Neoplasms | Genetic Predisposition to Cancer | Environment

United States
National Cancer Institute (NCI)

Recruiting

M9241 in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer or Intrahepatic Cholangiocarcinoma

Colorectal Neoplasms | Colorectal Cancer | Cholangiocarcinoma | Bile Duct Cancer | Bile Duct Neoplasms | Metastatic Colorectal Cancer (Mcrc) | Intrahepatic Cholangiocarcinoma (Icc) | Intrahepatic Bile Duct Cancer

United States
National Cancer Institute (NCI)

Recruiting

Olaparib in Subjects With Advanced Pancreatic Acinar Cell Carcinoma

Pancreatic Acinar Cell Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis From Colorectal, Appendiceal, Small Bowel, Gastric, Cholangiocarcinoma, Breast, Ovarian, or Other Gynecologic Primary Cancer

Gynecologic Cancer | Colorectal Neoplasms | Colorectal Cancer | Ovarian Neoplasms | Peritoneal Neoplasms | Ovarian Cancer | Peritoneal Carcinomatosis | Appendiceal Neoplasms | Appendiceal Cancer | Gynecologic Neoplasms

United States

Clinical Trials Sponsored by Singula Institute

Sponsors and Collaborators

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CROs in Malta

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