Search clinical trials for: [11C]ORM-13070

Total 392 results

Centre for Addiction and Mental Health

Completed

Exploring Regulation and Function of Dopamine D3 Receptors in Alcohol Use Disorders: A [11C]-(+)-PHNO Study

Alcohol Use Disorder

Canada
Gitte Moos Knudsen

Completed

Evaluation of [11C]Cimbi-36 as an Agonist PET Radioligand for Imaging of 5-HT2A Receptors

Healthy

Denmark
Amsterdam UMC, location VUmc

Unknown

Excitatory Amino Acids and Activated Microglia After Traumatic Brain Injury: a (R)-[11C]PK11195 PET Study

Traumatic Brain Injury

Netherlands
Imperial College London
GlaxoSmithKline

Terminated

I2PETPG - Imidazoline2 Binding Sites in a Group of Participants Diagnosed With AD (I2PETPG)

Alzheimer Disease

United Kingdom
University of Aarhus
Novo Nordisk A/S; Lundbeck Foundation; Svend Faelding Humanitarian Foundation; Copenhagen... and other collaborators

Terminated

Gastrointestinal Motility Among Diabetes Patients

Diabetes Mellitus | Gastrointestinal Motility Disorder | Change of Transit or Circulation | Diabetic Autonomic Neuropathy

Denmark
Rajesh Narendran

Completed

Characterization of [11C]Flumazenil to Image GABA Transmission in Healthy Adult Subjects and Subjects With Alcohol Dependence

Alcoholism

United States
National Institute of Diabetes and Digestive and...

Completed

Assessment of Beta Cell Mass by PET Scans With [11C] Dihydrotetrabenazine (DTBZ) in Longstanding Type 1 Diabetes.

Type 1 Diabetes
AstraZeneca

Completed

Positron Emission Tomography (PET) Study With (11C)Flumazenil to Determine Central GABAA Receptor Occupancy of AZD7325 (PET)

Anxiety

Sweden
NYU Langone Health
National Institute on Aging (NIA)

Completed

Locus-coeruleus Function in Normal Elderly and AD Risk (LEAD)

Alzheimer Disease

United States
AstraZeneca

Completed

Positron Emission Tomography (PET) Study With (11C) Flumazenil to Determine Central GABAA Receptor Occupancy of AZD6280 (PET)

Anxiety

Sweden
AstraZeneca

Completed

Positron Emission Tomography (PET) Study With [11C]Raclopride to Determine Central D2 Dopamine Occupancy of SEROQUEL (PET)

Depression

Sweden
GlaxoSmithKline

Completed

A Study to Compare Two Different Brain Imaging Techniques in Healthy Volunteers and in Schizophrenic Patients

Schizophrenia

Spain
National Institute of Mental Health (NIMH)

Completed

Protein Synthesis in the Brain of Patients With Fragile X Syndrome

Healthy Volunteers | Fragile X Syndrome

United States
IRCCS San Raffaele

Completed

11C-choline PET/CT Based Helical Tomotherapy as Innovative Treratment Approach for Bone Metastases in Prostate Cancer Patients.

Prostate Cancer

Italy
IRCCS San Raffaele

Completed

Radiation Treatment of Lymph Node Recurrence From Prostate Cancer : is 11C-choline PET/CT Predictive of Survival Outcomes?

Prostate Cancer

Italy
National Institute of Mental Health (NIMH)

Completed

PET Whole Body Biodistribution and Test Retest Bain Imaging Studies Using a Phosphodiesterase 4 Inhibitor (R)-[11C]Rolipram

Healthy | Dosimetry

United States
National Institute of Mental Health (NIMH)

Completed

PET Brain and Whole Body Distribution Studies for Nociceptin/Orphanin FQ Peptide (NOP) Receptor Using [11C]NOP-1A

Depression | Pain | Anxiety

United States
University of Aarhus

Completed

Effect of Obeticholic Acid on Transport of Bile Acids in PBC Examined by 11C-cholyl-sarcosine PET/CT

Primary Biliary Cirrhosis

Denmark
Université de Sherbrooke

Completed

PET Study of Cerebral Metabolism of 11C-acetoacetate and 18F-FDG in Patients Under Moderate Ketosis (TEP-KD)

Healthy
Dart NeuroScience, LLC

Terminated

Study of the Inhibition of [11C]R-rolipram Binding to Brain Phosphodiesterase - 4 (PDE-4) by HT-0712

Healthy Elderly Volunteers

United States
AHS Cancer Control Alberta

Completed

A Study for Patients With Prostate Cancer to See Whether Delivering an Extra Dose of Radiation to Parts of the Body With More Cancer is Better Than Standard Treatment in Which the Same Dose of Radiation is Given Throughout the Prostate Gland (PET PRO)

Prostatic Neoplasms

Canada
Boehringer Ingelheim

Completed

12 / 48 Week Pivotal PFT vs PBO in COPD I

Pulmonary Disease, Chronic Obstructive

United States, Australia, China, Germany, New Zealand, Taiwan
H. Lundbeck A/S

Completed

D2 Dopamine Receptor Occupancy After Oral Dosing of Lu AF35700 in Healthy Men Using [11C]-PHNO as Tracer Compound

Healthy Men

United Kingdom
Washington University School of Medicine

Terminated

Predictors of AAA Expansion and/or Rupture

Abdominal Aortic Aneurysm (AAA)

United States
Commissariat A L'energie Atomique
Assistance Publique - Hôpitaux de Paris

Unknown

Evaluation of 11 C-Choline PET-CT for Detection of Hepatocellular Carcinoma (CHOLPET)

Hepatocellular Carcinoma

France
National Institute on Alcohol Abuse and Alcoholism...

Completed

PET Imaging of DHA Metabolism

Healthy

United States
Ottawa Heart Institute Research Corporation

Active, not recruiting

ASV Effects on Myocardial Energetics and Sympathetic Nerve Function in Heart Failure and Sleep Apnea. (AMEND)

Heart Failure | Obstructive Sleep Apnea | Central Sleep Apnea

Canada
GlaxoSmithKline

Completed

An Open Label Positron Emission Tomography (PET) Study of GSK618334 in Healthy Male Subjects Using 11C-PHNO as PET Ligand

Substance Dependence

United Kingdom
Assistance Publique - Hôpitaux de Paris

Unknown

Prognosis Value of the Neuronal Damage in Early Multiple Sclerosis (Flumatep_2)

Multiple Sclerosis

France
National Institute of Mental Health (NIMH)

Recruiting

Functional Relevance of Dopamine Receptors in Healthy Controls and Patients With Schizophrenia: Characterization Through [11C]NNC-112 and [18F]Fallypride Positron Emission Tomography

Schizophrenia | Schizoaffective Disorder

United States
AbbVie

Terminated

[11C]-PBR28 Positron Emission Tomography Study to Evaluate the Effect of ABT 555 in Subjects With Relapsing Forms of Multiple Sclerosis

Multiple Sclerosis

United Kingdom
Institut National de la Santé Et de la Recherche...

Unknown

PET With [18F]Flumazenil as an Index of Neurodegeneration in MS (FLUMA-SEP-T)

Multiple Sclerosis | Relapsing-Remitting Multiple Sclerosis
IRCCS San Raffaele

Completed

Assessment of Predictive Role of [11C] Choline PET/CT on Survival in Prostate Cancer Patients With Biochemical Failure Without Androgen Deprivation Therapy

Prostate Cancer

Italy
Shanghai Mental Health Center
Yantai University

Completed

Assessing Dopamine Transporter Occupancy in the Healthy Adult Brain With Toludivenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET)

Major Depressive Disorder

China
Université de Sherbrooke
McMaster University; University of Ottawa

Completed

Effects of Fructose/Glucose-rich Diet on Brown Fat in Healthy Subjects (GB7) (GB7)

Type2 Diabetes

Canada
University of California, San Diego
National Institute of Mental Health (NIMH)

Completed

Monoamine Contributions to Neurocircuitry in Eating Disorders

Eating Disorder

United States
Yale University
National Center for Complementary and Integrative Health (NCCIH)

Recruiting

CBD-Microglia PET Study

Healthy | CBD

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

C-11 Choline PET-CT Scan in Finding Metastases in Patients With Newly Diagnosed High-Risk Prostate Cancer

Prostate Cancer

United States
National Institute of Neurological Disorders and...
Uniformed Services University of the Health Sciences

Recruiting

Neural Basis of Decision-Making Deficits in Traumatic Brain Injury

Traumatic Brain Injury

United States
Shanghai Mental Health Center
Yantai University

Recruiting

Assessing Dopamine Transporter Occupancy in the Patients With Depression Brain With Toludesvenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET)

Major Depressive Disorder

China
Tharick Pascoal
National Institute on Aging (NIA)

Recruiting

Head-to-Head Harmonization of Tau Tracers in Alzheimer's Disease (HEAD)

Alzheimer Disease

United States, Canada, Spain
Hoffmann-La Roche

Completed

A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers

Healthy Volunteer, Alzheimer's Disease

Sweden
GlaxoSmithKline
Quintiles, Inc.

Completed

A PH I Pilot Imaging Study to Evaluate Molecular Imaging Methods in HVs and pSS Pts

Autoimmune Diseases

United Kingdom
Abbott

Completed

Exploratory Positron Emission Tomography (PET) Study to Evaluate the Effects of ABT-614 on [11C]-(+)-PHNO Binding Potential to D3 Receptors in the Brain

Healthy Volunteers

Canada
The European Uro-Oncology Group
Centre for Human Drug Research, Netherlands

Completed

Imaging Staging and Response Prediction in Metastatic Hormono-Sensitive Prostate Cancer Patients Receiving Enzalutamide

Prostate Cancer Metastatic

Netherlands
Rigshospitalet, Denmark

Recruiting

The Pill Project - Oral Contraceptive and Serotonergic Brain Signaling

Major Depressive Disorder | Sexual Behavior | Mood Change | Mood Disturbance | Affect Altered | Affect Blunted | Drug Mechanism

Denmark
Medical University of Vienna

Completed

Effects of ECT on Monoamine Oxidase A in Depression Investigated With PET

Major Depression

Austria
Imperial Brands PLC
Nerudia Ltd

Completed

An Exploratory PET-study of Deposition, Disposition and Brain Uptake of [11C]Nicotine After Inhalation of 2 Nicotine Formulations Via the myBluTM E-cigarette in Smokers

Healthy Volunteers

Sweden
AstraZeneca

Completed

PET Study to Determine Muscarinic Receptor Occupancy in Lungs After Inhalation of AZD2115 and Tiotropium

Healthy Volunteers

Sweden
National Institute of Mental Health (NIMH)

Recruiting

Novel PET Radioligands as Inflammatory Biomarkers in Rheumatoid Arthritis and Myositis

Rheumatoid Arthritis | Healthy Volunteers | Myositis | Inflammatory

United States

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