Search clinical trials for: Cholesterol metabolism

Total 29393 results

University of Jena

Completed

Effects of Beta-glucan From Barley and Oats on Glucose and Lipid Metabolism, and Satiety (gLUCAn)

Glucose Metabolism | Lipid Metabolism | Satiety

Germany
Stanford University
Nordic Naturals

Completed

Effect of Fish Oil on Plasma Triglycerides in Adults

Hypertriglyceridemia

United States
Diabetes Foundation, India
National Diabetes Obesity and Cholesterol Foundation

Completed

Pre-meal Load of Raw Almonds and Postprandial Hyperglycemia

Intervention

India
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

The Effect of Statin Treatment on Arterial Wall Inflammation as Assessed With 68Ga-DOTATATE PET-CT (CARAMEL)

Diabetes Mellitus, Type 2 | Vascular Inflammation

Netherlands
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Wolman Disease (BioWolman) (BioWolman)

Cholesterol Ester Storage Disease | Acid Lipase Deficiency | Acid Cholesteryl Ester Hydrolase Deficiency, Wolman Type

Germany, India, Sri Lanka
Duke University
Eggland's Best

Completed

PROSPective Evaluation of Fortified Eggs Related to Improvement in The Biomarker Profile for Your Health (PROSPERITY)

Obesity | Hypercholesterolemia | Hyperlipidemia | Vitamin Deficiency

United States
Inova Health Care Services

Terminated

Effects of Evolocumab on Platelet Reactivity in Patients With Diabetes Mellitus (ISS-DMII)

Diabetes Mellitus, Type 2 | Percutaneous Coronary Intervention | Dyslipidemia Associated With Type II Diabetes Mellitus

United States
Universitas Airlangga

Completed

Adiponectin, ICAM-1, VCAM-1 Levels and Metabolic Syndrome in Obese Adolescents (ICAM; VCAM)

Hyperglycemia | Hypertension | Obesity | Metabolic Syndrome | Hypertriglyceridemia | Abdominal Obesity | HDL Cholesterol, Low Serum

Indonesia
Akrikhin
Russian National Atherosclerosis Society

Completed

Statin Monotherapy or Statins in Combination With Ezetimibe in Patients for Prevention of CVD (UNISON)

Cardiovascular Diseases | Lipid Metabolism Disorders

Russian Federation
University of Alberta

Completed

Kefir Cholesterol Lowering Pilot Study

Hypercholesterolemia

Canada
Rush University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Pilot Study of a Lifestyle Intervention on the Metabolic Syndrome (3ELM Study) (3ELM)

Metabolic Syndrome

United States
The Affiliated Hospital of Qingdao University

Completed

Bioavailability and Bioequivalence of Ezetimibe Tablets in Healthy Subjects

Hyperlipidemias

China
Thorne Research Inc.
Indena S.p.A

Terminated

Effects of Quercetin on Metabolic Health

Aging | Lipid Metabolism | Quercetin

United States
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company
Daiichi Sankyo Germany

Completed

SurveY Followed by a Retrospective Chart Review to Describe the Key Factors Leading to Physician's Decision to Treat Patients at High and Very High Cardiovascular Risk With hyperchOlesterolemia or Mixed Dyslipidemia With NUSTENDI®

Hypercholesterolemia | Mixed Dyslipidemia

Germany
Amgen

Completed

Study to Assess in Home Use of Evolocumab (AMG 145) Administration Using Either an Automated Mini-doser or a Prefilled Autoinjector/Pen

Mixed Dyslipidemia | Primary Hypercholesterolemia

United States, Canada
Amgen

Completed

Evolocumab Compared to LDL-C Apheresis in Patients Receiving LDL-C Apheresis Prior to Study Enrollment

Hypercholesterolemia

France, Germany, United States, Czechia, Italy, Australia, Spain, United Kingdom
The University of Hong Kong

Enrolling by invitation

Statin and Bone Health

Diabetes Mellitus, Type 2

Hong Kong
Amgen
TIMI Study Group

Completed

LAPLACE-TIMI 57: Low-density Lipoprotein Cholesterol (LDL-C) Assessment With PCSK9 monoclonaL Antibody Inhibition Combined With Statin thErapy (LAPLACE)

Hyperlipidemia

United States, Canada, Denmark, Czechia, Hungary
Amgen

Completed

Reduction of Low-Density Lipoprotein Cholesterol (LDL-C) With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study (RUTHERFORD)

Hypercholesterolemia, Familial
Touro University, California

Completed

Investigating the Production of Lipoproteins and Acetyl-CoA During a Ketogenic Diet (PLAK)

Cholesterol Metabolism | Ketone Metabolism

United States
Amgen

Completed

Monoclonal Antibody Against PCSK9 to Reduce Elevated LDL-C in Subjects Currently Not Receiving Drug Therapy for Easing Lipid Levels-2 (MENDEL-2)

Hyperlipidemia

United States, Denmark, Taiwan, Korea, Republic of, Australia, Belgium, Canada, South Africa, France, Turkey
Amgen

Completed

Trial Assessing Efficacy, Safety and Tolerability of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition in Paediatric Subjects With Genetic Low-Density Lipoprotein (LDL) Disorders (HAUSER-RCT)

Heterozygous Familial Hypercholesterolemia

United States, Canada, Italy, Norway, Belgium, Turkey, Australia, New Zealand, Austria, Czechia, South Africa, Poland, Spain, Switzerland, Netherlands, Taiwan, Finland, Brazil, Portugal, Slovenia, Russian Federation, Hungary, United... and more
Amgen

Completed

LDL-C Assessment With PCSK9 Monoclonal Antibody Inhibition Combined With Statin Therapy-2 (LAPLACE-2)

Hyperlipidemia

United States, Denmark, France, Italy, Czechia, Taiwan, Switzerland, Korea, Republic of, Germany, Hong Kong, Netherlands, Australia, Belgium, Canada, Hungary, South Africa, Russian Federation, Spain, United Kingdom, Sweden, Mexico
Amgen

Completed

Monoclonal Antibody Against PCSK9 to Reduce Elevated Low-density Lipoprotein Cholesterol (LDL-C) in Adults Currently Not Receiving Drug Therapy for Easing Lipid Levels (MENDEL)

Hyperlipidemia

United States, Denmark, Australia, Belgium, Canada
Amgen

Completed

Estimation Study to Assess the Effect of Severe Renal Impairment and End-stage Renal Disease Hemodialysis on the Pharmacokinetics of Evolocumab

Hyperlipidemia | Mixed Dyslipidemia

United States
Amgen

Completed

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects (GAUSS)

Hyperlipidemia

United States, Denmark, Australia, Belgium, Spain, Finland, Sweden, Canada
Resverlogix Corp

Completed

Safety, Pharmacokinetic Study of RVX000222 in Healthy Subjects and Subjects With Low HDL Cholesterol

Cardiovascular Disease | Atherosclerosis | Dyslipidemia | Acute Coronary Syndrome

United States
Yale University

Withdrawn

Mechanisms and Interventions to Address Cardiovascular Risk of Gender-affirming Hormone Therapy in Trans Men

Hypertension | Hyperlipidemias

United States
University of Coimbra
AstraZeneca

Completed

Rosuvastatin Effect on Atherosclerotic Plaque Metabolism (ROPPET-NAF)

Cardiovascular Diseases | Atherosclerosis | Molecular Imaging

Portugal
Hospices Civils de Lyon

Active, not recruiting

Assessment of Different Equations to Accurately Calculate LDL Cholesterol (LDL FORMULA)

Dyslipidemias | Lipid Disorder

France
New York Medical College

Completed

Human Placental-Derived Stem Cell Transplantation (HPDSC)

Mucopolysaccharidosis I | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Niemann-Pick Disease | Mucopolysaccharidosis VI | Wolman Disease | Adrenoleukodystrophy | Batten Disease | Metachromatic Leukodystrophy | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Fucosidosis | Gaucher... and other conditions

United States
NewAmsterdam Pharma

Completed

Study to Evaluate the Effect of Obicetrapib in Combination With Ezetimibe as an Adjunct to HIS Therapy (ROSE2)

Dyslipidemias | Hypercholesterolemia | High Cholesterol

United States
Yuhan Corporation

Completed

Rosuvastatin/Amlodipine vs Atorvastatin/Amlodipine in Hypertension Patient With Dyslipidemia (CORONA)

Hypertension | Dyslipidemias

Korea, Republic of
University of Alicante

Completed

Improvement of Physical and Physiological Parameters Through the Use of a Mobile App

Hypertension | Obesity | Body Weight | Diet, Healthy | Machine Learning | Cholesterol; Lipidosis

Spain
University Hospital, Clermont-Ferrand
UMR 1019, Unité de Nutrition Humaine, INRA, Centre Auvergne-Rhône Alpes; UMR...

Completed

Nutritional Transitions to More Plant Proteins and Less Animal Proteins: Understanding the Induced Metabolic Reorientations and Searching for Their Biomarkers (ProVegOmics) (ProVegOmics)

Metabolic Syndrome | Hypertriglyceridemia | Fasting Blood Sugar Above Normal | Lower Than Standard HDL-cholesterol Level | Slightly Elevated Blood Pressure

France
Amgen

Completed

Effects of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition on Arterial Wall Inflammation in Patients With Elevated Lipoprotein(a) (Lp(a)) (ANITSCHKOW)

Subjects With Hyperlipidemia, Dyslipidemia

Canada, Netherlands, United States
Amgen

Completed

Open Label Study of Long Term Evaluation Against LDL-C Trial (OSLER)

Hypercholesterolemia

United States, Denmark, Finland, Czechia, Hungary, South Africa, Spain, Australia, Belgium, Canada, Netherlands, Germany, Sweden, Hong Kong, Japan, Singapore, United Kingdom, Norway
Skogli Health and Rehabilitation Center

Completed

Effects of a Single Dose of Brazil Nuts on Blood Lipids

Cholesterol Level, High

Norway
Lisa Gallagher
The Cleveland Clinic; National Endowment for the Arts, United States; Cuyahoga...

Terminated

Arts & Health Education to Improve Health, Resilience, and Well-Being

Depression | Heart Diseases | Stroke | Multiple Sclerosis | Hypertension | Obesity | Diabetes | Chronic Pain | Asthma | Anxiety | COPD | CHF | High Cholesterol

United States
Gloria Vega
Regeneron Pharmaceuticals; Aventis Pharmaceuticals

Terminated

Effect of PCSK9-Antibody (Alirocumab) on Dyslipidemia Secondary to Nephrotic Syndrome

Nephrotic Syndrome

United States
NYU Langone Health

Withdrawn

Evolocumab In Advanced Chronic Kidney Disease Trial (EVO-CKD)

Chronic Kidney Diseases | High Cholesterol

United States
Amgen

Completed

Safety, Tolerability and Efficacy on Low Density Lipoprotein Cholesterol (LDL-C) of Evolocumab in Participants With Human Immunodeficiency Virus (HIV) and Hyperlipidemia/Mixed Dyslipidemia

Subjects With Hyperlipidemia, Dyslipidemia and HIV Infection

Canada, France, United States, Belgium, Italy, Spain, Switzerland, United Kingdom, South Africa, Portugal, Australia, Greece, Brazil, Romania, Poland
Amgen

Completed

Durable Effect of PCSK9 Antibody CompARed wiTh placEbo Study (DESCARTES)

Hypercholesterolemia

United States, Denmark, Belgium, Czechia, Austria, Australia, Canada, Hungary, South Africa
Bioksan
Analysis and Research Network, S.L

Completed

Clinical Trial to Demonstrate the Efficacy of a Dietary Supplement in Decreasing Cardiovascular Risk

Low-Moderate Hypercholesterolemia

Spain
Addpharma Inc.

Completed

A Study to Evaluate the Efficacy and Safety of AD-221 and AD-221A

Primary Hypercholesterolemia

Korea, Republic of
Ayub Teaching Hospital
Khyber Medical University Peshawar

Completed

Effect of Amlodipine on the Lipid Profile of Newly Diagnosed Hypertensive Patients

Hypertension | Hypercholesterolemia | Cholesterol Deposition
Health Clinics Limited

Withdrawn

Study of the Safety, Tolerability and Efficacy of Metabolic Combination Treatments on Cancer (METRICS)

Cancer | Overall Survival

United Kingdom
Cumberland Pharmaceuticals

Completed

Dose-ranging Efficacy and Pharmacokinetics Study of Intravenous Atorvastatin in Hypercholesterolemic Patients

Dyslipidemias | Hypercholesterolemia

United States
Robert Rosenson
University of Michigan; University of Toronto; Amgen

Completed

The Effects of Evolocumab in Patients With Diabetes and Atherosclerotic Vascular Disease

Type2 Diabetes | Microvascular Dysfunction | Atherosclerotic Vascular Disease

United States, Canada
Sanofi

Completed

A Study to Evaluate the Efficacy and the Safety of Single Pill Combination (SPC) Ezetimibe/Rosuvastatin in Chinese Adult Patients With Primary Hypercholesterolemia Not Adequately Controlled on Statin Therapy (ROZEL)

Hypercholesterolemia

China

Search clinical trials for: Cholesterol metabolism

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