Search clinical trials for: Dose escalation
Total 21232 results
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Universitaire Ziekenhuizen KU LeuvenKU LeuvenCompletedInflammatory Bowel DiseasesBelgium
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Taiho Oncology, Inc.TerminatedAdvanced Solid TumorsUnited States
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Taiho Oncology, Inc.TerminatedAdvanced Solid TumorsItaly, Spain, United States, Netherlands, United Kingdom
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National Cancer Institute (NCI)Active, not recruitingRecurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Oropharyngeal Squamous... and other conditionsUnited States, Puerto Rico, South Africa
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Veloxis PharmaceuticalsCompletedHealthy VolunteersUnited States
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Frederick R. Ueland, M.D.ArtemiLifeActive, not recruiting
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National Cancer Institute (NCI)NRG OncologyActive, not recruitingEndometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Adenocarcinoma | Recurrent Uterine Corpus Cancer | Stage IIIA Uterine Corpus Cancer AJCC v7 | Stage IIIB Uterine Corpus Cancer AJCC v7 | Stage IIIC Uterine Corpus Cancer AJCC v7 | Stage IVA Uterine Corpus Cancer... and other conditionsUnited States
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PfizerTerminatedMelanoma | Carcinoma, Renal Cell | Breast Neoplasms | Liver Neoplasms | Colorectal Neoplasms | Pancreatic Neoplasms | Mesothelioma | Neoplasms, Squamous Cell | Prostate NeoplasmsUnited States
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M.D. Anderson Cancer CenterActive, not recruitingTriple-Negative Breast Carcinoma | Stage I Breast Cancer AJCC v7 | Stage IA Breast Cancer AJCC v7 | Stage IB Breast Cancer AJCC v7 | Stage II Breast Cancer AJCC v6 and v7 | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7 | Stage III Breast Cancer AJCC v7 | Stage IIIA... and other conditionsUnited States
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Basilea PharmaceuticaCompletedNeoplasmsBelgium, United Kingdom, Germany, Switzerland
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Merck Sharp & Dohme LLCActive, not recruitingMetastatic Non-Small Cell Lung CancerPoland, United States, Argentina, Austria, Brazil, Chile, China, Colombia, France, Germany, Israel, Japan, Korea, Republic of, Mexico, Spain, Taiwan, Thailand, Turkey, United Kingdom
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M.D. Anderson Cancer CenterActive, not recruitingStage IB Lung Non-Small Cell Carcinoma AJCC v7 | Stage II Lung Non-Small Cell Cancer AJCC v7 | Stage IIA Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIB Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIIA Lung Non-Small Cell Cancer AJCC v7 | Stage I Lung Non-Small Cell Cancer AJCC v7 | Stage...United States
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National Cancer Institute (NCI)Active, not recruitingAcute Myeloid Leukemia | Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myelodysplastic/Myeloproliferative... and other conditionsUnited States
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Syneos HealthSynerK Pharmatech (Suzhou) LimitedCompletedElevated Low-Density Lipoprotein CholesterolAustralia
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University of Texas Southwestern Medical CenterActive, not recruiting
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Janssen Research & Development, LLCActive, not recruitingMultiple MyelomaUnited Kingdom, United States, France, Netherlands, Denmark
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Eisai Co., Ltd.Active, not recruiting
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National Cancer Institute (NCI)Active, not recruitingInvasive Breast Carcinoma | Triple-Negative Breast Carcinoma | Stage II Breast Cancer AJCC v6 and v7 | Stage III Breast Cancer AJCC v7United States
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Noxopharm LimitedTerminatedMetastatic Castration-resistant Prostate Cancer and Other Solid TumorsUnited States
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Revolution Medicines, Inc.Active, not recruitingAdvanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | Non-Small Cell Lung Cancer (NSCLC) | Colorectal Cancer (CRC)United States, Spain, France, Korea, Republic of, Malaysia, Taiwan, Italy, Thailand, Australia, Czechia, Singapore, Poland, Serbia
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Peloton Therapeutics, Inc., a subsidiary of Merck...Active, not recruitingKidney Cancer | Renal Cell Carcinoma | Clear Cell Renal Cell Carcinoma | ccRCC | RCCUnited States
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Eisai Inc.Active, not recruitingAdvanced NeoplasmsUnited States, United Kingdom
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Byondis B.V.Active, not recruitingSolid TumorBelgium, Italy, Netherlands, United Kingdom
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Medical College of WisconsinActive, not recruitingUnresectable Pancreatic CancerUnited States
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Institut de Recherches Internationales ServierADIR, a Servier Group companyActive, not recruitingAcute Myeloid LeukemiaUnited Kingdom, Spain, France, Hungary, Korea, Republic of, Poland
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Famewave Ltd.Bristol-Myers SquibbActive, not recruitingMelanoma | Pancreatic Cancer | Ovarian Cancer | Solid Tumor | Non Small Cell Lung Cancer | Colorectal Adenocarcinoma | Papillary Thyroid CancerSpain, United States, Israel
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AbbVieActive, not recruitingCancer | Advanced Solid Tumors | Metastatic Solid Tumors | Triple-Negative Breast Cancer (TNBC) | Non-small-cell-lung-cancer (NSCLC)United States, Australia, France, Israel, Spain, Taiwan
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Immune-Onc TherapeuticsCompletedSolid Tumor, AdultUnited States
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National Institute of Allergy and Infectious Diseases...CompletedRabies | Rabies ImmunisationUnited States
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Hoffmann-La RocheActive, not recruitingMetastatic Melanoma | Non-small Cell Lung Cancer (NSCLC) | Solid Tumors | Esophageal Squamous Cell Carcinoma (ESCC) | Small Cell Lung Cancer (SCLC)United States, Korea, Republic of, Denmark, France, Spain, New Zealand
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Hoffmann-La RocheCompletedAcute Myeloid LeukemiaAustralia, Italy, Canada, United Kingdom, United States, Denmark, Spain, Taiwan, Germany, France
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Helix BioPharma CorporationTheradexTerminatedNon-Small Cell Lung CancerUnited States
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St. Jude Children's Research HospitalChildren's Hospital of Philadelphia; National Heart, Lung, and Blood Institute... and other collaboratorsActive, not recruitingHemophilia BUnited States, United Kingdom
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Peptinov SASCompletedKnee OsteoarthritisFrance
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Baylor College of MedicineNational Cancer Institute (NCI); The Methodist Hospital Research Institute; Center...Active, not recruitingHodgkin Disease | Hodgkin Lymphoma | Non-Hodgkin LymphomaUnited States
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Hasselt UniversityZiekenhuis Oost-LimburgCompleted
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Harpoon TherapeuticsActive, not recruitingMultiple Myeloma | Multiple Myeloma in Relapse | Multiple Myeloma With Failed Remission | Multiple Myeloma of BoneUnited States, France, Spain
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Shanghai EpimAb Biotherapeutics Co., Ltd.TerminatedAdvanced Solid TumorsChina, Australia, United States
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National Institute of Allergy and Infectious Diseases...CompletedSchistosomiasisUnited States
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University of Colorado, DenverActive, not recruitingHigh Grade Myelodysplastic SyndromesUnited States
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National Institute of Allergy and Infectious Diseases...PPD; Rho Federal Systems Division, Inc.; Immune Tolerance Network (ITN); Seagen...CompletedDiffuse Cutaneous Systemic Sclerosis | Scleroderma | dcSScUnited States
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ModernaTX, Inc.AstraZenecaActive, not recruitingDose Escalation: Relapsed/Refractory Solid Tumor Malignancies or Lymphoma | Dose Expansion: Triple Negative Breast Cancer, HNSCC, Non-Hodgkins, Urothelial Cancer, Immune Checkpoint Refractory Melanoma, and NSCLC LymphomaUnited States, Israel, Australia
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PfizerActive, not recruitingBreast Cancer | Small Cell Lung Cancer | Ovarian CancerUnited States, China, Japan, Mexico, Bulgaria, Argentina
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National Cancer Centre, SingaporeTerry Fox FoundationCompletedNasopharyngeal CarcinomaSingapore
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AstraZenecaParexelActive, not recruitingRelapsed or Refractory Classical Hodgkin LymphomaItaly, United States, United Kingdom, Canada, Spain, France, Denmark
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TyrNovo Ltd.Active, not recruitingHead and Neck Cancer | Squamous Cell Carcinoma of Head and Neck | Metastatic Solid Tumor | Colorectal Adenocarcinoma | Solid Tumor, Adult | Recurrent Solid TumorUnited States, Israel
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Memorial Sloan Kettering Cancer CenterVanderbilt UniversityActive, not recruitingSolid Tumors | Preoperative Aerobic TrainingUnited States
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4D Molecular TherapeuticsActive, not recruitingChoroideremiaUnited States
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Medikine, Inc.TerminatedAdvanced or Metastatic Solid TumorsUnited States
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Vertex Pharmaceuticals IncorporatedCompleted