Search clinical trials for: Drug interaction

Total 260888 results

Temple University
National Institute on Drug Abuse (NIDA); University of Pennsylvania

Completed

Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study

Cocaine-Related Disorders | Cocaine Dependence | Cocaine Abuse | Cocaine Addiction

United States
Oregon Health and Science University

Enrolling by invitation

Assessing Patient-provider Interactions During the Preoperative Anesthesia Consult (IMPLICIT)

Healthcare Disparities | Minority Health | Racism

United States
Oncotherapeutics
Takeda

Completed

Ixazomib as a Replacement for Carfilzomib and Bortezomib for Multiple Myeloma Patients

Multiple Myeloma

United States
IRCCS San Raffaele

Completed

COMMUNIcation and Patient Engagement at Diagnosis of PAncreatic CAncer (COMMUNICARE)

Pancreatic Cancer | Diagnosis | Interaction

Italy
Centre Medicina Esportiva i Osteopatia, Spain

Completed

Systemic Adverse Effects After Osteopathic Treatment and Vitamin C

Oxidative Stress | Adverse Effects | Ascorbic Acid

Spain
Seoul National University Bundang Hospital

Enrolling by invitation

A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin on the Pharmacokinetics of Methotrexate in Elderly Subjects

Drug Interactions

Korea, Republic of
Boryung Pharmaceutical Co., Ltd

Completed

A Study to Evaluate Drug-drug Interactions and Safety Between "BR3006-1", "BR3006-2", and "BR3006-3" in Healthy Volunteers

Diabetes Mellitus

Korea, Republic of
Bristol-Myers Squibb

Completed

A Study to Assess the Effect of Multiple Doses of Itraconazole, Gemfibrozil, or Carbamazepine on BMS-986278 in Healthy Participants

Healthy Participants

Canada
Pharmacotherapies for Alcohol and Substance Use...
Yale University; United States Department of Defense; VA Connecticut Healthcare... and other collaborators

Completed

Effect of Sublingual Formulation of Dexmedetomidine HCl (BXCL501) - Alcohol Interaction Study

Post Traumatic Stress Disorder (PTSD) | Alcohol Use Disorder (AUD)

United States
National Institutes of Health Clinical Center (CC)

Completed

Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy Volunteers (YODA)

Healthy Volunteers

United States
Dr. Noah Biotech Inc.

Completed

Multiple Dose Study to Evaluate Drug-drug Interactions, Safety and Tolerability of NDC-002 in Healthy Volunteers

Stroke | Stroke Sequelae

Korea, Republic of
Boehringer Ingelheim

Completed

Drug-drug Interaction Between Digoxin, Furosemide, Metformin, and Rosuvastatin

Healthy

Germany
MDI Health
Hadassah Medical Organization

Completed

Assessment of a Novel Algorithm System for Polypharmacy Patient Medication Safety and Consultation

Polypharmacy Patients

Israel
Vigonvita Life Sciences

Completed

Drug-Drug Interaction (DDI) Study for TPN171H

Erectile Dysfunction

China
Instituto de Investigación Sanitaria de la Fundación...

Completed

Interaction Between Benralizumab and Basophils in Eosinophilic Asthma (BASEAS)

Asthma; Eosinophilic

Spain
Fujian Akeylink Biotechnology Co., Ltd.

Completed

Drug-Drug Interaction Study of Itraconazole With GST-HG171/Ritonavir in Healthy Participants

Healthy Participant

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

Drug-Drug Interaction Study Between Henagliflozin Proline and Hydrochlorothiazide

Diabetes in Adults

China
Southeast University, China

Completed

Effects of Glucocorticoid Combined With Vitamin C and Vitamin B1 on Microcirculation in Severe Septic Shock

Septic Shock

China
Helwan University

Active, not recruiting

The Impact of Oral Vitamin C in Prevention for Post Operative Atrial Fibrillation (POAF) in Coronary Artery Bypass Surgery (CABG) Patients

Post Operative Atrial Fibrillation

Egypt
Pfizer

Terminated

A Drug-Drug Interaction Study to Estimate the Effect of PF-07081532 on the Pharmacokinetics of Dabigatran and Rosuvastatin in Overweight or Obese Adult Participants

Healthy

United States
Pfizer

Completed

Drug-Drug Interaction Study Assessing Effect of Carbamazepine on PF-07321332 Boosted With Ritonavir

Healthy Participant

United States
Pfizer

Completed

Drug-Drug Interaction Study to Estimate the Effect of PF-07321332/Ritonavir and Ritonavir on Midazolam in Healthy Participants

Healthy Participants

Belgium
DICE Therapeutics, Inc.

Completed

A Drug-Drug Interaction Study to Assess the Pharmacokinetics of DC-806 When Orally Administered Alone, When Coadministered With Itraconazole, and When Coadministered With Carbamazepine in Healthy Adult Participants

Healthy Volunteers

United States
Sanofi

Completed

Study of Drug-drug Interaction of the Effects of Gemfibrozil and Rifampicin on SAR442168 in Healthy Adult Subjects

Multiple Sclerosis

United States
Agomab Spain S.L.

Completed

Drug-Drug Interaction Study With AGMB-129 and Midazolam in Healthy Participants

Healthy Volunteers

Belgium
LI YAN

Completed

Effect of Azole/Echinocandin Use on Tacrolimus Pharmacokinetics

Kidney Transplant Patients

China
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
Ministero della Salute, Italy; Istituto Nazionale di Genetica Molecolare, Milan... and other collaborators

Active, not recruiting

Novel Epigenetic Biomarker for Prematurity Related Neurodevelopmental Disorders in Childhood

Premature Birth

Italy
Bristol-Myers Squibb

Completed

A Study to Evaluate the Drug-drug Interaction Potential of BMS-986196 in Healthy Participants

Healthy Volunteers

United States
NHS Greater Glasgow and Clyde
British Heart Foundation; University of Glasgow

Completed

Clinical Study of UMOD NKCC2 Interaction on Salt-sensitivity in Hypertension (UMOD)

Cardiovascular Diseases | Hypertension

United Kingdom
Bristol-Myers Squibb

Completed

A Study to Evaluate the Drug-drug Interaction of BMS-986196 With Oral Contraceptives in Healthy Female Participants

Healthy Female Volunteers

United States
Hanmi Pharmaceutical Company Limited

Completed

A Study to Evaluate the Drug-drug Interaction and Safety of RLD2301 and RLD2007 in Healthy Volunteers

Healthy Volunteers

Korea, Republic of
Hanmi Pharmaceutical Company Limited

Completed

A Study to Evaluate Pharmacokinetic/Pharmacodynamic Drug-drug Interaction and Safety/Tolerability Between RLD2202 and RLD2203

Healthy

Korea, Republic of
Donders Centre for Cognitive Neuroimaging
Dr. Hanneke den Ouden, Donders Centre for Cognition, Radboud University; Dr... and other collaborators

Completed

Dopamine and Cognition

Sulpiride's Effect on Striatal BOLD Signal During Working Memory Gating | Interaction of Sulpiride, Average Reward Rate and Evidence Accumulation | Interaction of Sulpiride, Average Reward Rate and Cognitive Effort

Netherlands
Deciphera Pharmaceuticals LLC

Completed

A Phase 1b/2 Study of Rebastinib (DCC-2036) in Combination With Paclitaxel in Patients With Advanced or Metastatic Solid Tumors

Locally Advanced or Metastatic Solid Tumor

United States
University of Cape Town
Wellcome Trust; Medecins Sans Frontieres, Netherlands

Completed

Standard Versus Double Dose Dolutegravir in Patients With HIV-associated Tuberculosis (RADIANT-TB)

HIV Infections | Tuberculosis

South Africa
CTI BioPharma
Covance

Completed

Drug-Interaction Study to Evaluate the Effect of Rifampin, a Potent CYP3A4 Inducer, on the Systemic Exposure of Pacritinib in Healthy Subjects

Healthy Subjects

United States
Centre Hospitalier Universitaire, Amiens

Withdrawn

Evaluation of Interaction Between Immunosuppressive Drugs and Protein-bound Uremic Toxins in Renal Transplant Patients (DRUGTOX)

Immunosuppression | Kidney Transplant | Uremic; Toxemia

France
Obafemi Awolowo University
University of Liverpool

Completed

Pharmacokinetic Interaction Between Nitazoxanide and Atazanavir/Ritonavir in Healthy Volunteers

Drug Interaction

Nigeria
Paion UK Ltd.
University Medical Center Groningen; QPS Holdings LLC

Completed

Assessment of the Pharmacodynamic and Pharmacokinetic Interaction of Remimazolam and Remifentanil

Anesthesia

Netherlands
Boehringer Ingelheim

Completed

Investigation of Potential Drug-drug Interaction of Volasertib With Itraconazole in Patients With Various Tumours

Neoplasms

Hungary
Cinclus Pharma Holding AB

Completed

Effect of Clarithromycin on PK of Linaprazan, Linaprazan on PK of Clarithromycin and Linaprazan on PK of Midazolam

Pharmacokinetics | Safety Issues | Tolerability | Drug Interaction

Sweden
AstraZeneca
Parexel

Completed

A Study to Assess the Effects of Fluvoxamine on Savolitinib Exposure in Healthy Male Subjects

Healthy Male Subjects

United States
Amgen

Completed

A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications

Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

United States
ViiV Healthcare

Completed

Drug-drug Interaction (DDI) Study of GSK3640254 With Darunavir/Ritonavir (DRV/RTV) and Etravirine (ETR)

HIV Infections

United States
Pfizer

Completed

A Drug-Drug Interaction Study Between PF-06882961 and PF-06865571 in Healthy Adult Participants and Overweight Adults or Adults With Obesity Who Are Otherwise Healthy

Healthy Volunteer

United States
Bristol-Myers Squibb

Completed

A Study to Investigate the Interaction of BMS-986322 and a Combined Oral Hormonal Contraceptive (Ethinyl Estradiol [EE]/Norethindrone [NET]) in Healthy Female Participants

Healthy Participants

United States
Washington State University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters

Interaction | Endogenous Biomarkers

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Study Of Fluzoparib (SHR3162) on Patients With Recurrent Ovarian Cancer

Recurrent Ovarian Cancer

China
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Withdrawn

Pharmacokinetic Interactions of ENG Subdermal Implants With Long-Acting Cabotegravir (CAB-LA) and LA Rilpivirine (RPV-LA) (CARLA)

HIV-1-infection
National Institute of Allergy and Infectious Diseases...
ViiV Healthcare

Suspended

Drug-Drug Interactions Between Rifapentine and Dolutegravir in HIV/LTBI Co-Infected Individuals

HIV Infection | LTBI

United States, Haiti, Botswana, Brazil, Thailand, Zimbabwe, Malawi, Peru, South Africa

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