Search clinical trials for: General Safety

Total 275001 results

Nimble Science Ltd.
Lallemand Health Solutions

Not yet recruiting

The Safety and Efficacy of a Probiotic Intervention on SIBO and Related Gastrointestinal Symptoms

Small Intestinal Bacterial Overgrowth

Canada
GlaxoSmithKline

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of GSK3915393 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis
89bio, Inc.

Recruiting

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

United States
Children's Hospital of Soochow University

Recruiting

Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation

AML, Childhood | C-KIT Mutation | Refractory AML | Relapse/Recurrence | Core Binding Factor Acute Myeloid Leukemia

China
Centre Hospitalier Universitaire de Liege

Recruiting

Is Local Injection of Mesenchymal Stem Cells After Endoscopic Dilation Safe and Does it Improve the Outcome of Intestinal Stricture in Patients With Crohn's Disease?

Efficacy | Safety Issues

Belgium
MB PHARMA s.r.o.

Recruiting

Clinical Trial to Demonstrate the Safety and Efficacy of DUOFAG®

Bacterial Infections | Surgical Wound Infection | Surgical Site Infection | Staphylococcus Aureus Infection | Pseudomonas Aeruginosa Infection

Czechia
UCB Biopharma SRL

Not yet recruiting

A Study to Test the Long-term Safety and Tolerability of Brivaracetam in Study Participants With Childhood Absence Epilepsy or Juvenile Absence Epilepsy

Childhood Absence Epilepsy | Juvenile Absence Epilepsy
RenJi Hospital
Guangdong Ruishun Biotech Co., Ltd

Recruiting

Safety and Efficacy Study of CD19-CAR-DNT Cells in Autoimmune Diseases

Systemic Lupus Erythematosus | Systemic Sclerosis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Idiopathic Inflammatory Myopathies

China
Henrik Schytz

Recruiting

Safety and Efficacy of Botulinum Toxin A in Patients With Trigeminal Neuralgia

Trigeminal Neuralgia

Denmark
UMC Utrecht
Health Holland; Dutch Kidney Foundation; Servicio Madrileno De Salud (SERMAS); European... and other collaborators

Recruiting

First-in-human Study to Examine Safety of a New Peritoneal Dialysis Device (WEAKID) in End-stage Kidney Disease Patients (CORDIAL)

Chronic Kidney Diseases | Renal Insufficiency, Chronic | Kidney Failure, Chronic

Netherlands, Italy, Spain
Noema Pharma AG

Not yet recruiting

Efficacy and Safety of Gemlapodect in Adults and Adolescents With Tourette Syndrome (Allevia2)

Tourette Syndrome
Valenta Pharm JSC

Recruiting

Efficacy and Safety of Ingavirin®, Capsules, 60 mg, in Children With Influenza and Other Acute Respiratory Viral Infections

Influenza, Human | Common Cold | Acute Respiratory Infection

Russian Federation
ViiV Healthcare
GlaxoSmithKline

Not yet recruiting

First Time in Human Study of Long Acting VH4524184 Formulations

HIV Infections

United States
Urotronic Inc.

Recruiting

Safety and Effectiveness of the Optilume® BPH Catheter System in a Post-Market Study (PEAK)

Benign Prostatic Hyperplasia

United States
Alexion Pharmaceuticals, Inc.

Not yet recruiting

Study of Ultomiris® (Ravulizumab) Safety in Pregnancy

Pregnancy | Paroxysmal Nocturnal Hemoglobinuria (PNH) | Atypical Hemolytic Uremic Syndrome (aHUS) | Ultomiris-exposed Pregnant/ Postpartum | Generalized Myasthenia Gravis (gMG) | Neuromyelitis Optica Spectrum Disorder (NMOSD)
University Hospital, Grenoble

Not yet recruiting

Evaluation of the Safety of Inhaled Sedation With Isoflurane in Head Trauma Patients (IsoSAFE)

Traumatic Brain Injury

France
Assistance Publique - Hôpitaux de Paris

Recruiting

Safety Registry of a Fecal Microbiota Transplant Cohort (COSMIC-FMT)

Clostridium Difficile Infections

France
Genrix (Shanghai) Biopharmaceutical Co., Ltd.

Not yet recruiting

A Study to Evaluate the Safety, Immunogenicity, and Pharmacokinetics of GR2102 in Healthy Adult

Respiratory Syncytial Virus Infections

China
Amgen

Recruiting

A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome

Sjogren's Syndrome

United States
Chen Xiaoping

Not yet recruiting

Efficacy and Safety of Neoadjuvant Therapy in Patients With Resectable HCC Screened by a Multimodal Deep Learning Model.

HCC
University of Massachusetts, Worcester
University of Colorado, Denver; National Institute of Mental Health (NIMH); Ohio... and other collaborators

Not yet recruiting

Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part B (Jaspr-PartB)

Suicidal Ideation | Self Harm | Suicide Attempt

United States
Merck Sharp & Dohme LLC

Recruiting

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Non Small Cell Lung Cancer

United States, Israel, Taiwan, Korea, Republic of, Switzerland, Hong Kong
ProGen. Co., Ltd.

Recruiting

A Study to Assess Safety, Pharmacokinetics and Pharmacodynamics of PG-102(MG12) in Healthy Volunteers

Healthy | Overweight

Korea, Republic of
University Hospital, Toulouse

Not yet recruiting

Safety Study for the Use of Rapamycin in Children With Familial Adenomatous Polyposis (RAPA-4-PAF)

Familial Adenomatous Polyposis

France
AstraZeneca
Parexel

Recruiting

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma (ACADIA)

Asthma

United States
Zhujiang Hospital

Not yet recruiting

Effectiveness of Atorvastatin in Preventing Cerebrovascular Events After Flow Diverter Implantation

Efficacy Endpoint: no New Cerebrovascular Adverse Events Within 1 Year | Safety Endpoint: no New Moderate or Serious Adverse Events Within 1 Year | All-cause Mortality Events (Within 1 Year) | Incident Ischemic Stroke Events (Within 1 Year) | New Hemorrhagic Stroke Events (Within 1 Year) | New... and other conditions
Johns Hopkins University
Magic That Matters

Not yet recruiting

Safety and Feasibility of Hyperkalemic Cardioplegia With Diazoxide in Cardiac Surgery (CPG-DZX) Trial

Myocardial Stunning

United States
Chengdu CoenBiotech Co., Ltd
Jiangsu Province Centers for Disease Control and Prevention; Changde First... and other collaborators

Recruiting

Clinical Trial to Explore the Skin Test Dosage of EEC in People Aged 18 to 65 Years Old and the Safety and Preliminary Efficacy in People Aged 3 to 75 Years Old.

Tuberculosis

China
Shanghai Eye Disease Prevention and Treatment Center
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Recruiting

Efficacy and Safety of Conbercept for Diabetic Macular Edema Combined With Severe Non-proliferative Diabetic Retinopathy

Diabetic Macular Edema

China
Kind Pharmaceuticals LLC

Not yet recruiting

A Study of Efficacy and Safety of AND017 in Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes
Incepta Pharmaceuticals Ltd
Institute for Developing Science and Health Initiatives, Bangladesh

Recruiting

A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edema

Macular Degeneration | Retinal Degeneration | Diabetic Retinopathy | Diabetic Macular Edema | Macular Edema | Retinal Disease

Bangladesh
RenJi Hospital

Not yet recruiting

A Clinical Trial Evaluating the Safety, Tolerability, and Preliminary Efficacy of HCL001 Cell Injection (Homologous Allogeneic Hepatocytes) in Patients With Decompensated Cirrhosis

Decompensated Cirrhosis
Bausch & Lomb Incorporated

Recruiting

A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in Children

Myopia

China
International Vaccine Institute
Bill and Melinda Gates Foundation; Xiamen Innovax Biotech Co., Ltd

Not yet recruiting

Immunogenicity and Safety of Hecolin® in HIV Positive/Negative Adults and in Children

Hepatitis E Virus Infection
Oswaldo Cruz Foundation
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Recruiting

Safety and Efficacy of Decentralized HCV Treatment vs Standard-of-Care in Rio de Janeiro (Brazil) (HCVPCL05/20)

Hepatitis C

Brazil
Cedars-Sinai Medical Center

Recruiting

Blunt Fascial vs. Veress Needle Peritoneal Entry in Laparoscopic Gynecologic Surgery (BluntFascial)

Laparoscopic Surgery

United States
First Affiliated Hospital of Harbin Medical University

Recruiting

Effectiveness and Safety of Finerenone in Chinese CKD Patients Without Diabetes Mellitus

Chronic Kidney Diseases

China
Zongxun Lin

Recruiting

The Effect of Ultrasound Real-time Guidance Technique on the Effectiveness and Safety of Labor Analgesia

Labor Analgesia

China
argenx

Recruiting

A Worldwide Pregnancy Safety Study to Assess Maternal, Fetal, and Infant Outcomes Following Exposure to Efgartigimod During Pregnancy and/or Breastfeeding.

Myasthenia Gravis

United States
Kind Pharmaceuticals LLC

Not yet recruiting

A Study of Safety and Efficiency of AND017 in Patients With Transfusion Dependent and Non-transfusion Dependent β-thalassemia

β -Thalassemia
Sun Jia

Recruiting

Efficacy and Safety of Portable Hydrogen Rich Water Machine is Used for Adjuvant Treatment of Patients With Hyperlipidemia

Hyperlipidemias

China
Poznan University of Medical Sciences

Not yet recruiting

ESPB vs iPACK+ACB in Total Knee Arthroplasty

Knee Osteoarthritis | Knee Arthritis | Knee Arthropathy | Knee Pain Chronic | Knee Disease | Knee Rheumatism

Poland
Seattle Children's Hospital
Children's Hospital of Philadelphia

Not yet recruiting

Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity

Craniopharyngioma | Hypothalamic Obesity | Hypothalamic Tumor

United States
Hopstem Biotechnology Inc.

Recruiting

A Safety and Tolerability Study of Human Forebrain Neural Progenitor Cells Injection (hNPC01) in Subjects With Chronic Ischemic Stroke

Chronic Ischemic Stroke

China
argenx

Not yet recruiting

A Non-interventional, Post-authorisation Safety Study of Patients Treated With Efgartigimod Alfa

Myasthenia Gravis
Chiang Mai University
Faculty of Medicine, Chiang Mai University

Not yet recruiting

Immunogenicity and Safety of Inactivated and Live-attenuated HAV Vaccine Among Thai Healthy Children and Adolescents (HAV-RCT)

Hepatitis A | Vaccine-Preventable Diseases | Hep A | HAV
Gustave Roussy, Cancer Campus, Grand Paris
Daiichi Sankyo

Recruiting

Dose-Expansion Modular Study To Explore the Safety, Tolerability, and Anti-tumor Activity of HER3- DXd Monotherapy and Combinations in Patients With Inoperable Advanced Breast Cancer (ABC) After Progression on T-DXd (ICARUSBREAST02)

Advanced Breast Cancer | HER2-positive Metastatic Breast Cancer | Breast Cancer Metastatic | HER2 Low Breast Carcinoma

France
argenx

Recruiting

A Phase 3 Study to Evaluate the Efficacy and Safety of Efgartigimod IV in Patients With Acetylcholine Receptor Binding Antibody Seronegative Generalized Myasthenia Gravis (ADAPT SERON)

Generalized Myasthenia Gravis

United States
Guangdong Second Provincial General Hospital

Not yet recruiting

To Assess Safety, Tolerability, and Efficacy of Anti-GPRC5D-CD19-CAR-T in Relapsed/Refractory Multiple Myeloma

Relapsed or Refractory Multiple Myeloma

China
Omeros Corporation

Recruiting

Long-Term Safety, Tolerability and Efficacy of OMS906 in Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

Switzerland, Germany, Ukraine, United Kingdom

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