Search clinical trials for: Immune modulation

Total 59450 results

University of California, San Francisco
Merck Sharp & Dohme LLC; Astellas Pharma Inc

Not yet recruiting

Enfortumab Vedotin and Pembrolizumab Combined With Radiotherapy in Muscle Invasive Bladder Cancer

Bladder Cancer | Muscle-Invasive Bladder Carcinoma | Stage IIIA Bladder Cancer AJCC v8 | Stage II Bladder Cancer AJCC v8

United States
AstraZeneca

Not yet recruiting

A Study to Investigate Efficacy and Safety of PT027 Compared With PT007 in Symptomatic Chinese Adults With Asthma (BAIYUN)

Asthma

China
UCB Biopharma SRL

Not yet recruiting

A Study to Evaluate the Safe and Effective Use of a Zilucoplan Auto-injector by Study Participants With Generalized Myasthenia Gravis

Generalized Myasthenia Gravis
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-88998377 for Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin | Relapsed B-cell NHL | Refractory B-Cell NHL

Turkey
Merck Sharp & Dohme LLC

Not yet recruiting

Substudy 06C: A Study of Sacituzumab Tirumotecan (MK-2870) With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

Esophageal Cancer | Esophageal Neoplasms | Gastroesophageal Adenocarcinoma | Gastroesophageal Junction
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Virus-associated Tumour Microenvironment (VIRONMENT)

Lymphoma | Cancers of the Lung | Cancer Anal Canal
Yuanquan Yang

Not yet recruiting

Siltuximab for the Prevention of Severe Immune-Related Adverse Events During Immune Checkpoint Inhibitor Rechallenge in Patients With Advanced Cancer, CIRES Trial

Advanced Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
University Hospital, Montpellier

Not yet recruiting

Specific Biomarkers of Immune-mediated Hepatitis Secondary to Immune Checkpoint Inhibitors (Pro-CHILI)

Immune-mediated Hepatitis

France
Anaveon AG
Merck Sharp & Dohme LLC

Not yet recruiting

A Study Evaluating ANV600 Single Agent or in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (EXPAND-1)

Advanced Solid Tumor
The Cleveland Clinic

Not yet recruiting

A Multi-Disciplinary Technology-Based Care for Diabetic Ketoacidosis in Patients With Type 1 Diabetes (DKA)

Diabetic Ketoacidosis

United States
Scientific Institute San Raffaele

Recruiting

The Lymphocytic Infiltrate of Lung Tumors. (TREGILC)

Lung Cancer | Immune System

Italy
Concerto Biosciences

Not yet recruiting

Topical ENS-002 for Atopic Dermatitis in Adults (EnSync)

Atopic Dermatitis | Atopic Dermatitis Eczema

United States
Chinese University of Hong Kong

Recruiting

Boiled Tree Nut for Oral Immunotherapy in Food-allergic Children

Food Allergy | Food Allergy in Children

Hong Kong
Tang-Du Hospital

Recruiting

Study on the Therapeutic Effect of Irinotecan Liposomes in Small Cell Lung Cancer

Small Cell Lung Cancer

China
King's College London

Not yet recruiting

Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases (PDO)

Breast Neoplasms
IRCCS San Raffaele
GlaxoSmithKline

Not yet recruiting

Antiviral Long Acting Drugs Landing in People Living With HIV (ALADDIN)

HIV | Antiviral Agents

Italy
Centre Hospitalier Universitaire de Saint Etienne
Sanofi Pasteur, a Sanofi Company

Recruiting

Analyzes of Nasal Tissue-resident Memory Immune Cells and Peripheral Memory Cells Able to Migrate to Airway Tissues (MUCOVAC) (MUCOVAC)

Healthy Volunteers

France
Xianmin Song, MD

Recruiting

Reduced Intensity Conditioning With Thiotepa Combined With Bu/Flu/Ara-C in Allo-HSCT for Relapsed or Refractory Peripheral T-cell Lymphoma.

Peripheral T Cell Lymphoma

China
Shanghai Simnova Biotechnology Co.,Ltd.

Not yet recruiting

F01 in the Treatment of Moderate-to-severe Refractory Systemic Lupus Erythematosus

Lupus Erythematosis

China
Changhai Hospital
Rui Therapeutics

Not yet recruiting

An Exploratory Clinical Study of Anti-CD19 CAR NK Cell (KN5501) in the Treatment of Relapsed/Refractory Immune Nephropathy

Nephropathy
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

United States
Ruijin Hospital

Recruiting

A Trial on the Recurrence Free Survival Rate of Type I AIP With High-risk of Recurrence

Type 1 AIP

China
Steno Diabetes Center Copenhagen
Aarhus University Hospital

Recruiting

Automated Insulin Delivery for Type 1 Diabetes - Beyond Glucose Metrics (AID-BEYOND)

Diabetes Mellitus, Type 1

Denmark
Guangdong Hengrui Pharmaceutical Co., Ltd

Not yet recruiting

Efficacy and Safety Study of SHR-1819 Injection in Adult Patients With Severe Atopic Dermatitis

Moderate to Severe Atopic Dermatitis

China
University of British Columbia

Recruiting

The UBC Long-distance Triathlon Adaptation Study (ULTRA)

Healthy Participants

Canada
Peter Timoney
Inflammasome Therapeutics

Not yet recruiting

Evaluation of K9 in Subjects With Thyroid Eye Disease (TED)

Thyroid Eye Disease

United States
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Efficacy and Safety of Dupilumab in Combination With Tofacitinib in Moderate to Severe Adult AD Patients

Atopic Dermatitis
Brigham and Women's Hospital
Gilead Sciences; Trutag Technologies

Not yet recruiting

Development of a Silica Microparticle Taggant System to Measure ART Adherence (TruTag)

Medication Adherence | Hiv | Compliance, Medication
Kerry Rogers

Not yet recruiting

Pirtobrutinib (LOXO-305) and Venetoclax for the Treatment of Patients With CLL or SLL Resistant to Covalent BTKi

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
David Ilan Sandberg

Not yet recruiting

Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies

Recurrent Ependymoma | Recurrent Medulloblastoma | CNS Malignancies

United States
KalVista Pharmaceuticals, Ltd.

Not yet recruiting

Open-Label Safety, PK, and Efficacy Trial of Sebetralstat (KVD900) in Pediatric Patients (Ages 2-11) With HAE Type I or II (KONFIDENT-KID)

Hereditary Angioedema
University Hospital, Clermont-Ferrand

Not yet recruiting

Validation of a French Version of the DHEQ (DHEQ-VALID)

Quality of Life | Dentin Hypersensitivity

France
University of Zurich

Recruiting

Mastocytosis Registry (of Zurich) (MastoR)

Mastocytosis | Hypertryptasemia

Switzerland
University Hospital, Montpellier
McGill University Health Centre/Research Institute of the McGill University...

Not yet recruiting

Effect of Binocular Treatment Using a Dichoptic Reading Application in Children With Convergence Insufficiency. (ALEDICE)

Ophthalmological Disorder
University of Cape Town

Recruiting

B.R.A.I.N in People Living With HIV Study (BRAIN)

HIV-associated Neurocognitive Disorders

South Africa
Walden Biosciences

Not yet recruiting

Study of WAL0921 in Patients With Glomerular Kidney Diseases

Diabetic Nephropathies | Minimal Change Disease | Primary Focal Segmental Glomerulosclerosis | Primary Membranous Nephropathy | Primary Immunoglobulin A Nephropathy
Gruppo Italiano Malattie EMatologiche dell'Adulto

Not yet recruiting

Observational Study on the Outcome of Patients With ITP Who Underwent Splenectomy After 2010

Primary Immune Thrombocytopenia
Castilla-La Mancha Health Service

Not yet recruiting

Clinical Utility of Tight Objectives of Advanced Hybrid Closed-loop Systems Among Type 1 Diabetes Patients (TightT1AHCL) (TightT1AHCL)

Type 1 Diabetes

Spain
University of Kiel
University Hospital Schleswig-Holstein

Not yet recruiting

Impact of Diet on the Microbiome-Immune-Brain Axis in Parkinson's Disease

Parkinson Disease

Germany
Hunter Holmes Mcguire Veteran Affairs Medical Center

Recruiting

Microbiome Modulation With Prebiotics in PTSD and Cirrhosis (RESIST-PTSD)

PTSD | Cirrhosis

United States
AstraZeneca

Recruiting

STEP: Phase IIIb Study of Benralizumab to Step-down Maintenance Therapy in Patients With Severe Eosinophilic Asthma (STEP)

Severe Eosinophilic Asthma

China
Institute of Hematology & Blood Diseases Hospital...

Recruiting

A Prospective Clinical Study of CD3-CD20 Bisspecific Antibody Based Therapy Combined With CD19-CAR T Cells in the Treatment of Relapsed Refractory B-cell Non-Hodgkin Lymphoma

B-cell Non-Hodgkin Lymphoma

China
Dow University of Health Sciences

Recruiting

A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH

Hypersensitivity | Dentin Sensitivity | Cervical Lesion

Pakistan
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Sequential Treatment of CD19 CARNK and 7x19 CAR-T in R/R B Cell Lymphoma (CD19-CARNK/T)

Mantle Cell Lymphoma (MCL) | Primary Mediastinal B-cell Lymphoma (PMBCL) | Diffuse Large B Cell Lymphoma( DLBCL)
ETH Zurich

Recruiting

Pilot Trial: Bioavailability Animal vs. Plant Protein Drink

Nutrition, Healthy | Leucine Sensitivity

Switzerland
First Affiliated Hospital of Zhejiang University
First Affiliated Hospital of Wenzhou Medical University; The Affiliated Hospital... and other collaborators

Recruiting

Primary Multiple Myeloma Who Achieved MRD Negativity After Induction Therapy, ASCT or Not

Multiple Myeloma | Minimal Residual Disease

China
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...
EMD Serono Research & Development Institute, Inc.

Recruiting

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Generalized Myasthenia Gravis

Japan
Seattle Children's Hospital

Not yet recruiting

REACT-01: Reversing Autoimmunity Through Cell Therapy

Systemic Lupus Erythematosus

United States
Nanjing IASO Biotechnology Co., Ltd.

Recruiting

A Phase III Study of Eque-cel in Subjects With Len-refractory RRMM (FUMANBA-03) (FUMANBA-03)

Multiple Myeloma

China
Wuhan University

Not yet recruiting

A Real-World Study of Neoadjuvant/Conversion Therapy for Locally Advanced or Metastatic Gastric Cancer

Gastric Cancer

China

Search clinical trials for: Immune modulation

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