Search clinical trials for: LPS endotoxin

Total 391 results

Boehringer Ingelheim

Completed

Effect of BIBT 986 Followed by BIBT 986 Given as IV Infusion on Tissue Factor Triggered Coagulation in Healthy Male Volunteers

Healthy
Brugmann University Hospital

Completed

Effect of Anti-Inflammatory Agents on Biological Responses to Endotoxin Inhalation in Healthy Subjects

Innate Immunity
Nanjing Luye Sike Pharmaceutical Co., Ltd.

Unknown

Dose Escalation and Pharmacokinetic Study of Paclitaxel Liposome Injection in Treating Patients With Advanced Solid Tumor After Failure From Conventional Treatments

Solid Tumors

China
Nanjing Luye Sike Pharmaceutical Co., Ltd.

Unknown

Weekly Paclitaxel Liposome Injection Plus Cisplatin in Preoperative Treatment of Breast Cancer

Breast Cancer

China
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Endotoxin and Bronchial Inflammation in Asthma

Lung Diseases | Inflammation | Asthma
Boehringer Ingelheim

Completed

Effect of Single Oral Dose BIRB 796 BS on Endotoxin-induced Inflammatory Responses in Healthy Human Subjects

Healthy
Nanjing Luye Sike Pharmaceutical Co., Ltd.

Unknown

Weekly and Every 3 Week Administration of Paclitaxel Liposome Injection in Metastatic Breast Cancer

Breast Cancer

China
Eisai Inc.

Terminated

A Study of Eritoran (E5564) Administered IV Over 14 Days Prior to and During Bone Marrow Engraftment in BMT Patients Who Have Received Myeloablative Conditioning Treatment and Are Receiving Bone Marrow or Stem Cells From Matched Related Donors

Leukemia

United States
University of California, Los Angeles
National Institute of Mental Health (NIMH)

Completed

Inflammation-Induced Depressed Mood: The Role of Social Neurocognitive Mechanisms

Depression

United States
Peking University

Unknown

Study on Neoadjuvant Chemotherapy for Advanced Gastric Cancer

Advanced Gastric Carcinoma

China
Washington University School of Medicine
Barnes-Jewish Hospital

Completed

Quantifying Airway Inflammation With Radiologic Tests

Lung Inflammation

United States
Washington University School of Medicine
Barnes-Jewish Hospital

Completed

PET Imaging of Endotoxin-induced iNOS Activation

Pneumonia

United States
Pfizer

Completed

PH-797804 LPS Study in Healthy Volunteers

Healthy

United Kingdom
Shanghai Changzheng Hospital

Unknown

Rifaximin Predicts the Complications of Decompensated Cirrhosis

Cirrhosis

China
Beth Israel Deaconess Medical Center
Walter Reed Army Medical Center

Completed

Docetaxel Followed by Radical Prostatectomy in Patients With High Risk Localized Prostate Cancer

Prostate Cancer

United States
Meditor SAS

Completed

Effects of Hemoperfusion With a Polymyxin B Membrane in Peritonitis With Septic Shock (ABDO-MIX)

Septic Shock | Peritonitis

France
University Medicine Greifswald

Unknown

LenusPro Safety (LPS) Study in Patients With PH

Pulmonary Hypertension

Austria, Germany, Netherlands
TNO
Alloksys Life Sciences B.V.

Completed

Microdose and First-In-Human (FIH) Study of Recombinant Human Placental Alkaline Phosphatase (hRESCAP)

Healthy

Netherlands
University of North Carolina, Chapel Hill
National Institute of Environmental Health Sciences (NIEHS)

Completed

Inhalation of 20,000 Endotoxin Units(EU) of Clinical Center Reference Endotoxin in Healthy Volunteers (Entox)

Healthy Adults

United States
Radboud University Medical Center

Completed

Concentration/Meditation Limits Inflammation

Autoimmune Diseases

Netherlands
Michelle Hernandez, MD
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Effect of Interleukin-1 Receptor Antagonist on Inhalation of 20,000 EU Clinical Ctr Reference Endotoxin in Normal Volunteers (Kintox)

Healthy Control Subjects

United States
Radboud University Medical Center

Completed

The Effects of Immunostimulation With GM-CSF or IFN-y on Immunoparalysis Following Human Endotoxemia

Sepsis | Inflammation | Endotoxemia | Multi Organ Dysfunction Syndrome

Netherlands
Janssen Research & Development, LLC

Completed

Safety, Tolerability and Pharmacodynamic Activity of JNJ-26528398 in Healthy Male Participants

Healthy Participants

Belgium
TNO
Unilever R&D; Netherlands Metabolomic Center (NMC), The Netherlands

Completed

Ex Vivo LPS Stimulation in Healthy and Compromised Subjects

Healthy | Compromised Health

Netherlands
OPKO Health, Inc.

Completed

Effects of TT301 on Cytokine Levels Post Endotoxin Challenge

Traumatic Brain Injury

United States
Rush University Medical Center

Completed

Increased Gut Permeability to Lipopolysaccharides (LPS) in Parkinson's Disease

Parkinson's Disease | Multiple System Atrophy

United States
Charite University, Berlin, Germany
Pfizer

Unknown

Temsirolimus in Recurrent Primary Central Nervous System (CNS) Lymphoma

Recurrent or Refractory Primary CNS Lymphoma

Germany
Green Beat

Completed

Probiotic Sport Study

Inflammation | Endotoxemia | Oxidative Stress

Austria
Mahidol University

Completed

Accuracy of MRI-based Patients Matched Instruments vs Jig-based Instruments in Total Knee Arthroplasty (TKA)

Osteoarthritis of Knee
Baxter Healthcare Corporation

Completed

e-STEPS: Endotoxin-Associated Sterile Peritonitis Observational Study (e-STEPS)

Endotoxin-associated Sterile Peritonitis

United Kingdom, Germany, Hungary, Netherlands, Portugal
Meir Medical Center

Unknown

Testosterone Undecanoate and Quality of Life of Men and Spouses

Hypogonadism
Seoul National University Hospital

Unknown

Comparison of Outcomes in Mobile and Fixed-bearing Total Knee Arthroplasty

Osteoarthritis of Knee

Korea, Republic of
Seoul National University Hospital

Completed

Comparison of the Tibiofemoral Rotational Alignment After Mobile and Fixed Bearing Total Knee Arthroplasty

Osteoarthritis
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Study of Inhalation of 20,000 EU CCRE in Normal Volunteers Compared to Allergic Asthmatic Individuals (Endomac)

Hypersensitivity | Asthma

United States
University of North Carolina, Chapel Hill
National Institutes of Health (NIH)

Terminated

Safety Study of 20,000 EU of Clinical Center Reference Endotoxin in Allergic Adults With and Without Mild Asthma

Mild Allergic Rhinitis | Mild Allergic Rhinitis With Mild Asthma

United States
University of Nottingham

Unknown

Immune Function in Patients With Obstructive Jaundice

Obstructive Jaundice | Immune Tolerance | Disease as Reason for ERCP | Immune Dysfunction

United Kingdom
University of Lausanne
Centre Hospitalier Universitaire Vaudois

Completed

Lactate Metabolism After an Endotoxin Challenge in Healthy Humans

Sepsis

Switzerland
Azienda Ospedaliero, Universitaria Pisana

Unknown

Endotoxin in Gram-negative Septic Shock

Gram Negative Septic Shock

Italy
International Centre for Diarrhoeal Disease Research...
Göteborg University; Kyoto University

Completed

Effect of Probiotic on Immunogenicity of Oral Cholera Vaccine

Cholera

Bangladesh
Zimmer Biomet

Completed

A Study to Compare the NexGen LPS and LPS-Flex Knee Implants

Osteoarthritis | Total Knee Arthroplasty

United States, Canada
Govind Ballabh Pant Hospital

Completed

S. Endotoxin, Inflammatory Mediators and MRS Before and After Treatment in MHE (endtxninHE)

Hepatic Encephalopathy

India
AM-Pharma
CRM Biometrics GmbH; Sintesi Research Srl; Vigilex BV

Completed

Safety/Efficacy Study of Bovine Intestinal Alkaline Phosphatase in Patients With Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

Czech Republic, Italy
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Suitability of a Low Dose Lipopolysaccharide (LPS) Inhalation as a Challenge Model

Healthy

Germany
Università degli Studi dell'Insubria

Completed

Transumbilical Versus Transvaginal Specimen Retrieval at Minilaparoscopy

Postoperative Complications | Postoperative Pain | Intraoperative Complications | Patients Satisfaction

Italy
Pfizer

Completed

Single Dose Lipopolysaccharide (LPS) Study In Healthy Volunteers

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Maria Sklodowska-Curie National Research Institute...
Medical University of Gdansk; The Greater Poland Cancer Centre; Medical University... and other collaborators

Completed

Prospective Study of Quality of Life in Non-small Cell Lung Cancer (NSCLC) Patients Treated With/Without Postoperative Radiotherapy

Non-Small Cell Lung Cancer

Poland
Ewha Womans University

Completed

Do We Need High-Flexing Total Knee Arthroplasty to Improve the Survivorship and to Decrease the Incidence of Osteolysis?

Osteoarthritis

Korea, Republic of
Medical University of Vienna

Completed

The Role of the P2Y12 Receptor in Tissue Factor Induced Coagulation

Sepsis | Healthy Volunteers

Austria
Centre de Recherche en Nutrition Humaine Rhone-Alpe
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Metabolic Fate Modifications of Saturated Fats After an Overfeeding (SURNUT)

Inflammation | Obesity | Lipid Metabolism

France
Radboud University Medical Center
Maastricht University Medical Center

Completed

Anti-inflammatory Effects of Enriched Enteral Nutrition During Human Experimental Endotoxemia (VIHE)

Endotoxemia

Netherlands

Search clinical trials for: LPS endotoxin

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