Search clinical trials for: MTHFR genotype

Total 1430 results

University of Pittsburgh
National Institutes of Health (NIH); National Institute of Dental and Craniofacial...

Completed

Acute Pain Genomic Study

Osteoarthritis | Postoperative Pain

United States
AbbVie

Completed

A Study to Evaluate the Pharmacokinetics, Safety, and Efficacy of Glecaprevir/Pibrentasvir in Pediatric Subjects With Genotypes 1-6 Chronic Hepatitis C Virus (HCV) Infection (DORA)

Hepatitis C Virus (HCV)

United States, Belgium, Canada, Germany, Japan, Puerto Rico, Russian Federation, Spain, United Kingdom
University Medicine Greifswald

Completed

Impact of OCT1 and CYP2D6 Genotypes on Pharmacokinetics of Berberine in Healthy Volunteers (BERKI-1)

Pharmacokinetic Study in Healthy Volunteers

Germany
Damascus University

Completed

Corticosteroid Injection Combined With Cataract Surgery in Diabetic Eyes.

Cataract | Intravitreal Injection | Diabete Type 2 | Triamcinolone Acetonide

Syrian Arab Republic
University of Southern California

Completed

Alcohol Metabolism and Disease Risk in Asians (R21AA28365)

Healthy

United States
Columbia University

Completed

Evaluating Long Acting Beta Agonists Used to Treat Asthma Among Those With Either Arg/Arg or Gly/Gly Genotypes (ARGARG)

Asthma

United States
University of Mostar

Completed

MTHFR Mutation and Concentration of B12,Folic Acid,Homocysteine and HS CRP in the Blood of Pregnant Women With GDM.

Gestational Diabetes

Bosnia and Herzegovina
Centre Hospitalier Universitaire de Saint Etienne
Kyoto University, Graduate School of Medicine

Completed

Analysis of the Genotype/Phenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in France. (F3S)

Fuchs Endothelial Corneal Dystrophy

France
AbbVie

Completed

A Study to Evaluate Long-term Outcomes Following Treatment With ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 With or Without Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection (TOPAZ-I)

Chronic Hepatitis C Virus (HCV) Infection Genotype 1

Algeria, Australia, Belgium, Bulgaria, Canada, Denmark, Finland, France, Germany, Greece, Israel, Italy, Mexico, Netherlands, Norway, Poland, Portugal, Romania, Russian Federation, Saudi Arabia, Spain, Switzerland, Turkey, Austria, Ireland and more
IRCCS Burlo Garofolo

Completed

Genetic and Immunologic Characterization of IEI

Immunity Disorders | Inborn Errors of Immunity

Italy
Papworth Hospital NHS Foundation Trust
NHS Greater Glasgow and Clyde

Completed

PRIZE ET Sub-Study

Microvascular Angina

United Kingdom
Spanish Breast Cancer Research Group
Hoffmann-La Roche; IBEROAMERICAN COALITION FOR BREAST ONCOLOGY RESEARCH (CIBOMA)

Completed

Maintenance Treatment With Capecitabine Versus Observation in Breast Cancer Patients

Breast Cancer

Spain
Zhongshan Ophthalmic Center, Sun Yat-sen University

Completed

Genetic Diagnosis in Congenital Cataracts

Congenital Cataract

China
Vanderbilt University Medical Center

Completed

Preemptive Pharmacogenetic-guided Metoprolol Management for PostoperativeAtrial Fibrillation in Cardiac Surgery (PREEMPTIVE)

Post-operative Atrial Fibrillation

United States
Perspectum

Completed

Mapping Organ Health Following COVID-19 Disease Due to SARS-CoV-2 Infection (COVERSCAN)

COVID-19

United Kingdom
National Taiwan Normal University

Completed

Cardiorespiratory Fitness, Apolipoprotein E Genotype, and Cognitive Functions: A Prospective Study

Cognitive Change | Aging

Taiwan
Second Affiliated Hospital, School of Medicine,...

Completed

Comparison of Different Helicobacter Pylori Detection Methods in Patients With Chronic Atrophic Gastritis

Helicobacter Pylori Infection

China
National Taiwan Normal University

Completed

Acute Exercise on Neurocognitive Function Among Adults With/Without Generic Risk of AD

Alzheimer Disease 2 Due to Apoe4 Isoform

Taiwan
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Role of HLA Genes and Innate Immunity in the Phenotypic Variability of COVID-19 (3490)

COVID-19

Italy
Karolinska University Hospital

Active, not recruiting

Follow-up of Cell Changes in the Cervix

Cancer of Cervix

Sweden
University of Florida

Terminated

Genotype-guided Supportive Care in Symptom Treatment of Cancer Patients

Chemotherapy | Supportive Care | Genotyping

United States
Memorial Sloan Kettering Cancer Center

Completed

Interest and Impact of Skin Cancer Genetic Testing

Non-melanoma Skin Cancer (NMSC)

United States
Yonsei University

Completed

Precision Treatment With Angiotensin Converting Enzyme Inhibitor

Hypertension

Korea, Republic of
Queen Mary University of London
Nottingham University Hospitals NHS Trust; Barts & The London NHS Trust; Janssen-Cilag... and other collaborators

Completed

Telaprevir in Genotype 3 HCV (TIG3)

Hepatitis C

United Kingdom
University Hospital, Geneva

Terminated

Evaluation of Pupillometry for cyp2d6 Phenotyping in Children Treated With Tramadol (PUPICYP)

Drug Effect | Drug Intolerance | Cytochrome P450 CYP2D6 Enzyme Deficiency

Switzerland
Scripps Health
Bristol-Myers Squibb; Sanofi; Accumetrics, Inc.

Completed

Genotype Information and Functional Testing Study (GIFT)

Coronary Artery Disease

United States
University Medical Centre Ljubljana
University of Ljubljana, Faculty of Medicine; National Institute of Chemistry... and other collaborators

Completed

Genotype-phenotype Correlations in Children and Adults With CTNNB1 Mutation (Gen-Phe CTNNB1)

CTNNB1 Gene Mutation

Slovenia, Australia
University of Southern Denmark
Odense University Hospital

Completed

Implementation and Quality Assurance of DPYD-genotyping in Patients Treated With Fluoropyrimidines.

Breast Cancer | Gastric Cancer | Rectal Cancer | Bile Duct Cancer | Colon Cancer | Pancreas Cancer | Oesophageal Cancer | Adverse Drug Event

Denmark
Southern Illinois University Carbondale

Completed

EEG & Behavioral Predictors of Changes in Smoking Trajectories in Young Light Smokers

Nicotine Dependence

United States
R-Pharm
Almedis; Scientific Center EFiS; ChromSystemsLab

Completed

Efficacy and Safety of All-Oral Combination of Narlaprevir/Ritonavir and Sofosbuvir in Treatment-naïve Patients With Chronic Hepatitis C Genotype 1

Chronic Hepatitis c Genotype 1

Russian Federation
AeskuLab Pathology Prague
Institute of Biostatistics and analyses, Ltd.

Completed

Algorithm for Cervix Carcinoma Screening in CZ Using the Detection of HPV DNA and CINtec Plus (LIBUSE)

Algorithm for Cervix Carcinoma Screening

Czechia
University Medical Centre Maribor
Faculty of Medicine, University of Maribor

Completed

Genetics of Self-injurious Behaviour

Self-Injurious Behavior | Self Injurious Behavior Without Suicidal Intent
Hossam Hassan Aly Hassan El Sokkary

Completed

Cervical Carcinoma in Shatby University Hospital and Its Relation to Human Papilloma Virus

Cervical Cancer

Egypt
Shanghai Mental Health Center
Shanghai Jiao Tong University School of Medicine; Shanghai Municipal Science...

Completed

Efficacy of Exposure and Response Prevention(ERP) and SSRIs in Chinese OCD Patients

Mental Disorders | Obsessive-Compulsive Disorder | Anxiety Disorders

China
Universiti Sains Malaysia

Completed

Impact of CYP2C19 Genotype-guided Clopidogrel and Ticagrelor Treatment on Platelet Function Test and Metabolomics Profile

Coronary Artery Disease (CAD)

Malaysia
PharmaEssentia

Completed

The Pharmacokinetics of P1101 + Ribavirin in Interferon Treatment-Naïve Subjects With Chronic Hepatitis C Virus (HCV) Genotype 2 Infection

Hepatitis C, Chronic

Taiwan
Nalagenetics Pte Ltd
Indonesia University; SJH Initiatives; MRCCC Siloam Hospitals Semanggi

Active, not recruiting

CYP2D6 Genotypes and Breast Cancer Clinical Outcomes in the Indonesian Population

Breast Cancer

Indonesia
NYU Langone Health

Completed

Identify Predictors That Distinguish Between Tofacitinib Responders and Non-responders Based on Genotype and Cellular and Molecular Profiles From Pinch Biopsies, Blood and Stool Samples

Ulcerative Colitis

United States
University of Ulster
DSM Nutritional Products, Inc.

Enrolling by invitation

Intervention With Riboflavin to Improve Vascular Health and ENdothelial Functioning in Genetically at- Risk Adults (InteRVENE)

Hypertension | Blood Pressure

United Kingdom
Brigham and Women's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Interaction of Melatonin With MTNR1B Genotype on Glucose Control - Study 2

Circadian Rhythm | Melatonin | Glucose | Genes | Light

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Subjects 6 Through 11 Years of Age With Cystic Fibrosis and F/MF Genotypes

Cystic Fibrosis

Canada, France, Germany, United Kingdom, Israel, Australia, Spain, Netherlands, Denmark, Switzerland
Brigham and Women's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Interaction of Melatonin and MTNR1B Genotype on Glucose Control - Study 1

Circadian Rhythm | Melatonin | Glucose | Genes

United States
Cellectar Biosciences, Inc.

Completed

A Trial of NOV-205 in Hepatitis C Patients Who Failed Standard Therapy (NOV-205)

Hepatitis C

United States
Atlas Biomed

Terminated

Study of the Genome, Gut Metagenome and Diet of Patients With Incident Parkinson's Disease

Parkinson Disease | Genetic Predisposition

Russian Federation
Atlas Biomed

Completed

Study of the Genome, Gut Metagenome and Lifestyle of Patients With Incident Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2 | Genetic Predisposition | Metagenome

Russian Federation
AbbVie

Completed

A Study to Evaluate Long-term Outcomes Following Treatment With ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 With or Without Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection (TOPAZ-II)

Chronic Hepatitis C Virus (HCV) Infection Genotype 1

United States
Poznan University of Life Sciences

Completed

Vegetables Intake and Polymorphism TAS2R38 Gene by Healthy Adults

Diet Habit | Taste Disorders | Healthy Lifestyle

Poland
Universitas Padjadjaran

Completed

Disorders of Sex Development (DSD) 46.XY in Three Siblings

Genotype

Indonesia
AbbVie

Completed

A Study of the Effectiveness and Clinical Practice Use of Glecaprevir/Pibrentasvir in Adolescents With Chronic Hepatitis C Genotypes 1 to 6 in Russian Federation (DETI-2)

Hepatitis C Virus (HCV)

Russian Federation
Case Comprehensive Cancer Center

Completed

Apalutamide and Leuprolide in Intermediate and High-risk Prostate Cancer

Prostate Cancer

United States

Search clinical trials for: MTHFR genotype

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