Search clinical trials for: Moderate To Severe Dry Eye

Total 476528 results

Dompé Farmaceutici S.p.A

Recruiting

A Study to Evaluate Safety and Efficacy of a New Formulation of Recombinant Human Nerve Growth Factor (rhNGF) Eye Drop Solution in Patients With Dry Eye Disease (REDUCO)

Dry Eye Disease

United States, Italy
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor (AQUA)

Dermatitis Atopic

Chile, United Kingdom, United States, Canada, Turkey, Israel, Korea, Republic of
University of Alicante
Pharmactive Biotech Products S.L.U

Not yet recruiting

Effects of AffronEye®/ Crocuvis+® on Dry Eye Syndrome

Dry Eye Syndrome

Spain
Shanghai 6th People's Hospital

Not yet recruiting

Safety and Efficacy of Enhanced Recovery After Surgery in Neurocritical Care

Traumatic Brain Injury | Cerebrovascular Disease | Neurocritical Care | Moderate or Severe Coma

China
medac GmbH

Not yet recruiting

Efficacy and Safety of Methotrexate Versus Placebo in Adults With Atopic Dermatitis.

Moderate to Severe Atopic Dermatitis
EMS

Not yet recruiting

Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third Molars (ALIV)

Moderate Pain | Severe Pain
Olympic Ophthalmics, Inc.

Recruiting

A Usability Study of iTEAR100 For Combined EyeLid Microblepharoexfoliation and Neurostimulation

MicroBlepharoexfoliation, NuLids, iTEAR100, iLIDS100, Blepharitis, Dry Eye Syndrome

United States
LumiThera, Inc.
National Eye Institute (NEI)

Recruiting

Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITEIIIB)

Dry Age-related Macular Degeneration

United States
Morphic Therapeutic, Inc

Recruiting

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease (GARNET)

Inflammatory Bowel Diseases | Crohn's Disease

United States, Georgia
Telios Pharma, Inc.

Recruiting

A Study of TL-925 Ophthalmic Emulsion as a Treatment for Dry Eye Disease

Dry Eye Disease

United States
McMaster University
Center for Medicinal Cannabis Research

Not yet recruiting

Psilocybin in the Treatment of Cannabis Use Disorder: A-Proof-of-Concept Study (PSI_CUD)

Cannabis Use Disorder, Moderate | Cannabis Use Disorder, Severe
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis on Background Topical Corticosteroids (SHORE)

Dermatitis Atopic

Japan, Chile, Canada, Argentina, United States, Turkey, China
Amgen

Recruiting

A Study With Self-administered Rocatinlimab in Adolescent and Adult Participants With Moderate-to-severe AD (ROCKET-Outpost)

Atopic Dermatitis

United States, Canada
The University of Hong Kong

Recruiting

Therapeutic Efficacy and Safety of Non-Invasive RF Treatment in Refractory MGD

Dry Eye Syndromes | Meibomian Gland Dysfunction

Hong Kong
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis (ICONIC-ADVANCE 2)

Plaque Psoriasis

United States, Korea, Republic of, Taiwan, Germany, Poland, Brazil, Spain, Hungary, Australia, Canada, Romania
He Eye Hospital

Recruiting

Corneal and Tear Film Changes in Chinese Patients With Type 2 Diabetes

Dry Eye Disease | Tear Film | Corneal Nerve

China
Incyte Corporation

Recruiting

A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa (STOP-HS LTE)

Hidradenitis Suppurativa (HS)

United States, Austria, Belgium, Canada, Germany, Poland, Spain, Australia, Denmark, France, United Kingdom, Japan, Bulgaria, Netherlands, Czechia, Greece, Italy
Assistance Publique Hopitaux De Marseille

Not yet recruiting

Effects on Biotrauma of NMBAs and PP Association During ARDS (CURA-PRONE)

Moderate to Severe Acute Respiratory Distress Syndrome

France
Chang Gung Memorial Hospital

Recruiting

Dual-Polymer Hydroxypropyl Guar-and Hyaluronic Acid Lubricants in Rheumatoid Arthritis

Dry Eye Syndromes

Taiwan
JHM BioPharma (Tonghua) Co. , Ltd.

Recruiting

A Phase I/II, Randomized, Double-blind, Placebo, and Active Controlled Clinical Study to Evaluate the Safety, Tolerability, Immunogenicity, and Preliminary Efficacy of JHM03 in Subjects With Moderate to Severe Glabellar Lines

Moderate to Severe Glabellar Lines

China
Fidia Farmaceutici s.p.a.

Recruiting

Evaluation of Performance and Safety of Carbopol 980 NF 0.2%- Based Medical Device in the Management of Patients With Glaucomar or Ocular Hypertension and Concomitant Dry Eye Syndrome on Multiple Long-term Topical Hypotensive Therapy

Dry Eye Syndrome | Glaucoma and Concomitant Dry Eye Syndrome | Ocular Hypertension and Concomitant Dry Eye Syndrome | Multiple Long-term Topical Hypotensive Therapy

Italy
Ascletis Pharmaceuticals Co., Ltd.

Recruiting

A Study to Evaluate the Safety and Efficacy of ASC40 (Denifanstat) Tablets in the Treatment of Patients With Moderate to Severe Acne Vulgaris

Acne

China
Fidia Farmaceutici s.p.a.

Recruiting

Evaluation of Performance and Safety of Eye Drops With Hydroxypropyl-methylcellulose and Inositol in Drye Eye Disease

Dry Eye Disease Associated to Asthenopia and Accommodative Effort in Video Display Terminal Users

Italy
Fidia Farmaceutici s.p.a.

Recruiting

Evaluation of Performance and Safety of Eye Drops With Hyaluronic Acid 0.30% and 0.15%

Dry Eye Syndrome (DES)

Italy
The Hong Kong Polytechnic University
Alcon Research

Recruiting

Efficacy of a New Nanoemulsion Artificial Tear in Dry Eye Disease Management

Dry Eye Syndromes

Hong Kong
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

A Clinical Study to Compare the Safety and Pharmacokinetics of SHR-1314 Injection in Healthy Subjects at Different Specifications Devices

Moderate-to-Severe Plaque Psoriasis

China
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)

Dermatitis Atopic

Argentina, Japan, China, Czechia, Spain, United States, South Africa, United Kingdom, Denmark, Sweden, Turkey
ORA, Inc.
Stuart Therapeutics, Inc.

Recruiting

Safety and Efficacy of ST-100 (Vezocolmitide) Ophthalmic Solution 60 μg/ml Ophthalmic Solution in Subjects Diagnosed With Dry Eye Disease (DED)

Dry Eye Disease

United States
Eli Lilly and Company

Recruiting

A Study of LY3972406 in Adult Participants With Moderate-to-Severe Plaque Psoriasis

Plaque Psoriasis

United States
Seoul National University Hospital

Recruiting

Rezum for 30-80ml Patients With Moderate-severe LUTS to Study Surgical Principles for Median Lobe Enlargement

Prostatic Hyperplasia of the Medial Lobe

Korea, Republic of
Direction Centrale du Service de Santé des Armées

Recruiting

Preventive TREatment of Dry Eye in Patients Receiving Repeated Intravitreal Injections for Age-related Macular Degeneration (TREDIA)

Age-Related Macular Degeneration | Dry Eye Syndromes

France
Mabwell (Shanghai) Bioscience Co., Ltd.

Recruiting

Study to Evaluate the Pharmacokinetic Characteristics, Safety, Tolerability, and Preliminary Efficacy of 9MW1911 in Patients With Chronic Obstructive Pulmonary Disease (COPD).

Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

China
University of Southern California
Ophthalmic Surgeons & Consultants of Ohio, Inc.

Not yet recruiting

BroadBand Light for the Treatment of Dry Eye Disease

Dry Eye Syndromes | Meibomian Gland Dysfunction
Hanlim Pharm. Co., Ltd.

Recruiting

Observational Study on the Improvement of Dry Eye Syndrome, Treatment Satisfaction, and Intraocular Tolerance With Diquasol Eye Drops

Dry Eye Syndrome

Korea, Republic of
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

Evaluation of 611(Recombinant Humanized Anti-interleukin-4 Receptor Alpha IgG4 Monoclonal Antibody) in Chinese Adults With Moderate to Severe Atopic Dermatitis

Dermatitis, Atopic

China
St. Antonius Hospital

Recruiting

Future Optimal Research and Care Evaluation - Aortic Stenosis (FORCE-AoS)

Severe Aortic Valve Stenosis | Moderate Aortic Valve Stenosis

Netherlands
Shanghai Yueyang Integrated Medicine Hospital

Not yet recruiting

The Relationship Between Moderate-to-severe Psoriasis and Sleep Disturbance

Moderate-to-severe Psoriasis

China
Navamindradhiraj University

Recruiting

Effects of Antiplatelet and Antioxidant Agents on Drusen Progression: A Pilot, Prospective Cohort Study

Dry Age-related Macular Degeneration

Thailand
Aston University

Not yet recruiting

Protecting the Eyes of Gamers With Lubricating Eyedrops (PROTEGE)

Dry Eye Syndromes | Computer Vision Syndrome
Keymed Biosciences Co.Ltd

Not yet recruiting

Study of CM310 in Children Subjects With Moderate-to-severe Atopic Dermatis

Atopic Dermatitis
Tecnoquimicas

Recruiting

Management of the Ocular Surface With Preservative-Free Lubricants in Patients With Dry Eye

Dry Eye Disease

Colombia
He Eye Hospital

Not yet recruiting

Safety and Effectiveness of EyePeace on Signs and Symptoms of Dry Eye Disease

Evaporative Dry Eye

China
Guangzhou JOYO Pharma Co., Ltd
Chengdu JOYO pharma Co., Ltd.

Not yet recruiting

A Study to Evaluate JYP0061 Tablets in Patients With Moderate-to-severe Atopic Dermatitis

Moderate-to-severe Atopic Dermatitis
Southern California College of Optometry at Marshall...

Recruiting

Eyelid Androgen Treatment in Dry Eye

Aqueous Tear Deficiency | Meibomian Gland Dysfunction of Bilateral Eyes (Disorder)

United States
UCB Biopharma SRL

Not yet recruiting

A Study of Rozanolixizumab in Pediatric Study Participants With Moderate to Severe Generalized Myasthenia Gravis (roMyG)

Generalized Myasthenia Gravis
Indonesia University
Santen Pharmaceutical Co., Ltd.

Recruiting

Effectiveness of Diquafosol Prophylactic Therapy to Prevent Dry Eye Disease for Cataract Surgery Patients in Indonesia

Dry Eye Disease

Indonesia
St. Joseph's Healthcare Hamilton
Trudell Medical International

Not yet recruiting

Effect of OPEP on Mucus Plugging and Airflow Obstruction in Patients With Moderate-to-severe Asthma (AeroMUC)

Asthma

Canada
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

Korea, Republic of, United Kingdom, United States, Poland, Germany, Brazil, Spain, Taiwan, Hungary, Japan, Canada, Argentina, Australia
Novartis Pharmaceuticals

Recruiting

Secukinumab Drug Survival, Effectiveness and Tolerability in Pediatric Patients With Psoriasis (SPARROW)

Moderate-to-severe Plaque Psoriasis

Russian Federation
Genentech, Inc.

Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Vixarelimab in Participants With Moderate to Severe Ulcerative Colitis (UC)

Ulcerative Colitis

United States, Poland

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