Search clinical trials for: Subthalamic nucleus

Total 571 results

Cerevance

Completed

Phase 1 SAD/MAD Study of CVN766 in Healthy Volunteers

Tolerance | Safety Issues

Australia
Sanofi

Completed

Study to Assess the Plasma Concentration of Tolebrutinib Given as a Tablet to Adult Participants With Mild Hepatic Impairment Compared to Participants With Normal Hepatic Function

Hepatic Function Abnormal

United States, Belgium
University Hospital, Lille
Ministry of Health, France

Active, not recruiting

Predictive Factors and Subthalamic Stimulation in Parkinson's Disease (PREDI-STIM)

Parkinson's Disease

France
Medicines for Malaria Venture
Nucleus Network Ltd; Southern Star Research Pty Ltd.

Completed

A Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetic Profile of a Single Doses of MMV533.

Malaria

Australia
Medicines for Malaria Venture
Nucleus Network Ltd; Southern Star Research Pty Ltd.

Completed

MMV533 Plasmodium Falciparum Volunteer Infection Study

Malaria

Australia
Respira Therapeutics, Inc.

Completed

A Healthy Volunteer Study Evaluating the the Safety, Tolerability, and Pharmacokinetics of RT234

Healthy Volunteer

Australia
RANI Therapeutics

Completed

Study Evaluating PK of PTH Administered Orally Via RaniPill™ Capsule

Healthy Volunteers

Australia
JD Bioscience Inc.
Novotech (Australia) Pty Limited

Enrolling by invitation

First-in-Human Study of GM-60106 in Healthy Adults and Otherwise Healthy Adults With an Increased Body Mass Index and Markers of Non-Alcoholic Fatty Liver Disease

Non-alcoholic Steatohepatitis

Australia
Symvivo Corporation

Completed

Evaluating the Safety, Tolerability and Immunogenicity of bacTRL-Spike Vaccine for Prevention of COVID-19

COVID-19

Australia
AceLink Therapeutics, Inc.
Novotech (Australia) Pty Limited

Completed

To Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AL01211 in Healthy Volunteers

Autosomal Dominant Polycystic Kidney

Australia
Cochlear
University of Iowa

Completed

Implantation of the Cochlear™ Nucleus® Hybrid S Round Window (S-RW) in Adults

Sensorineural Hearing Loss

United States
Cochlear

Completed

Implantation of the Cochlear® Nucleus® System in Adults With Single-Sided Deafness

Single Sided Deafness

United States
Ashvattha Therapeutics, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of D-4517.2 After Subcutaneous Administration in Healthy Participants

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

Australia
Cochlear
Avania

Completed

Acceptance and Performance of CP1110 Sound Processor With Experienced Adult Cochlear Implant Recipients. (PINNA)

Adult Cochlear Implant Recipients

Australia
Gadjah Mada University

Completed

Learning Curve, Outcome Parameters, and MRI Assessment of Disc Evacuation After Transforaminal Percutaneous Endoscopic Lumbar Discectomy

Herniated Nucleus Pulposus

Indonesia
Haisco Pharmaceutical Group Co., Ltd.
Haisco Pharmaceutical(Australia) Pty Ltd.

Completed

A Study of Safety, Tolerability, and Pharmacokinetics of Single Ascending Dosed of HSK31858 in Healthy Volunteers

Healthy

Australia
Supernus Pharmaceuticals, Inc.

Completed

Evaluating the Safety and Relative Bioavailability of Three SPN-817 Treatments (A, B and C) in Healthy Adult Subjects

Healthy Volunteer

Australia
Pfizer

Completed

Pharmacokinetic Comparability Study in Healthy Participants - PF-06881894 On-Body Injector Relative to Prefilled Syringe

Healthy Volunteers

United States
ModernaTX, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of mRNA-6231 in Healthy Adults

Healthy Volunteers

Australia
Connect Biopharma Australia Pty Ltd

Completed

Safety, Tolerability and Pharmacokinetics of CBP-174 in Healthy Adults

Healthy Adult Subjects

Australia
Q32 Bio Inc.

Completed

Single and Multiple Ascending Dose Study of ADX-914 in Healthy Adult Volunteers

Safety Issues

Australia
Cortexyme Inc.

Completed

A Single and Multiple Ascending Dose Study of COR588

Healthy Volunteers

Australia
Basking Biosciences, Inc.

Completed

Study of DTRI-031 in Healthy Volunteers

Healthy Volunteers | Pharmacokinetics | Pharmacodynamics

Australia
HUYABIO International, LLC.

Completed

Drug-Drug Interaction Study of HBI-3000 and Paroxetine in Healthy Adult Male and Female Subjects

Drug-drug Interaction

United States, Australia
AN2 Therapeutics, Inc

Completed

A Study of Epetraborole Tablets in Subjects With Degrees of Renal Function

Renal Insufficiency

United States
Circadian Therapeutics Ltd
Neuroscience Trials Australia

Completed

First in Human Study of CT-1500 in Healthy Participants

Healthy

Australia
Bristol-Myers Squibb

Completed

Study of BMS-986158 in Subjects With Select Advanced Cancers (BET)

Advanced Tumors

United States, France, Australia, Spain, Canada
Bruce J Gantz

Completed

Hybrid Cochlear Implants in Severe to Profound Adults, Children, and Adolescents

Hearing Loss, High-Frequency

United States
Vania Martínez-Nahuel
ANID - Millennium Science Initiative Program - NCS17_03 Millennium Nucleus... and other collaborators

Terminated

EMA Baseline Screening System for Therapists Who Treat Youths With Depressive Symptoms

Depressive Symptoms

Chile
Alvotech Swiss AG
Iqvia Pty Ltd

Completed

Pharmacokinetics, Safety and Tolerability Study of AVT04 to EU Approved and US Licensed Stelara (Ustekinumab)

Psoriasis

Australia, New Zealand
Blade Therapeutics

Completed

Drug-Drug Interaction (DDI) Study in Healthy Volunteers

Drug Drug Interaction

Australia
Canopy Growth Corporation

Completed

Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of CHI-915 in Healthy Participants

Healthy Adults

United States
Apollomics (Australia) Pty. Ltd.
Novotech (Australia) Pty Limited; Apollomics Inc. (formerly CBT Pharmaceuticals...

Completed

APL-501 Study for Select Advanced or Relapsed/Recurrent Solid Tumors

Solid Tumor | Microsatellite Instability | Mismatch Repair Deficiency | Cancer of Unknown Primary Site

Australia
Foresee Pharmaceuticals Co., Ltd.

Completed

Multiple-Dose, Dose-Escalation Study to Evaluate the Safety/Tolerability and Pharmacokinetics of FP-045

Healthy Volunteers

Australia
Syneos Health

Completed

First-in-Human Study of SRT-015 in Healthy Subjects.

Nonalcoholic Steatohepatitis

Australia
University Hospital, Grenoble

Completed

Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Epilepsy (FRANCE)

Surgery | Partial Epilepsy

France
BioFactura Australia Pty Ltd.
Avance Clinical Pty Ltd.

Completed

Bioequivalence Phase I Study of BFI-751 Compared With EU and US-STELARA® in Healthy Adults

Psoriasis

Australia, New Zealand
Landos Biopharma Inc.

Completed

Safety, Tolerability and Pharmacokinetics of Oral NX-13 in Healthy Adults Male and Female Volunteers

Ulcerative Colitis

Australia
Inventage Lab., Inc.

Completed

A Clinical Trial to Assess Pharmacokinetic/Pharmacodynamic Profiles and Safety of IVL3001

Androgenetic Alopecia

Australia
Otsuka Pharmaceutical Development & Commercialization...

Completed

A Phase 1, Drug Interaction Study Between AVP-786 and Paroxetine and Between AVP-786 and Duloxetine in Healthy Subjects

Drug-drug Interaction

Australia
Protagonist Therapeutics, Inc.

Completed

Pharmacokinetics of PN-235 in Healthy Volunteers

Healthy Volunteers

Australia
Atridia Pty Ltd.

Terminated

A Trial of SHR-1703 in Healthy Subjects

Asthma

Australia
Cochlear
Mayo Clinic; University of Iowa; NYU Langone Health; Ohio State University; University... and other collaborators

Completed

Nucleus Hybrid L24 Extended Duration Post Approval Study (HED)

Hearing Loss
Novavax

Completed

Study to Evaluate the Immunogenicity and Safety of an Ebola Virus (EBOV) Glycoprotein (GP) Vaccine in Healthy Subjects

Ebola

Australia
TFF Pharmaceuticals, Inc.

Completed

Pharmacokinetic Profile of Voriconazole Inhalation Powder in Adult Subjects With Asthma

Asthma

Australia
BeiGene

Completed

Study of the Safety, Pharmacokinetics and Antitumor Activities of BGB-A317 in Participants With Advanced Tumors

Advanced Cancer

United States, Taiwan, Australia, Korea, Republic of, New Zealand
Altimmune, Inc.

Completed

ALT-801 in Healthy Overweight and Obese Volunteers to Study Safety and Tolerability

NASH - Nonalcoholic Steatohepatitis

Australia
BeiGene

Terminated

Study of BGB-A333 Alone and in Combination With Tislelizumab in Advanced Solid Tumors

Advanced Solid Tumors

Australia, Spain, New Zealand
Sciwind Biosciences APAC CO Pty. Ltd.
Hangzhou Sciwind Biosciences Co., Ltd.

Completed

To Evaluate the Safety, Tolerability, PK, and PD of XW003 Injection in Healthy Adult Participants (XW003)

Obesity | Type 2 Diabetes Mellitus | Nonalcoholic Steatohepatitis

Australia
Kasey Phifer
The National Centre for ElectroMagnetic Therapies CIC

Completed

Pulsed ElectroMagnetic Field (PEMF) Therapy in Treating Post-Traumatic Stress Disorder (PTSD) & Trauma

Unspecified Trauma- and Stressor-Related Disorder

United Kingdom

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