Search clinical trials for: Transcriptional Signature

Total 455 results

Morten Hostrup, PhD

Completed

Effect of Exercise on Muscle Proteome Signature

Healthy

Denmark
Potrero Medical

Withdrawn

Collective Accuryn Physiologic Signals and Signatures (CAPSS)

Sepsis | Critical Illness | Septic Shock | Acute Kidney Injury | Abdominal Compartment Syndrome

United States
St George's, University of London
Max Planck Institute for Infection Biology; Innovative Medicine Initiative

Completed

Vaccination In Pregnancy Gene Signature: VIP Signature Study

Pregnancy Related | Vaccination

United Kingdom
University Hospital, Montpellier

Completed

Better Delineation of BCL11B Related Phenotype and Epigenetic Signature.

Intellectual Developmental Disorder | BCL11B Related Disorder

France
Institut Curie

Completed

Isolation of Volatile Organic Compounds (VOCs) Related to the Olfactory Signature of Breast Cancer (KDOG2)

Breast Cancer | Surgery

France
Taipei Veterans General Hospital, Taiwan
Ministry of Science and Technology, R.O.C.

Completed

Neurologic Signatures of Chronic Pain Disorders

Chronic Pain | Fibromyalgia | Chronic Migraine

Taiwan
University of South Dakota
Iowa Physical Therapy Foundation

Completed

Correlation of Trust and Outcomes Following Physical Therapy for Chronic Low Back Pain

Chronic Low Back Pain | Physical Therapy | Trust

United States
VA Office of Research and Development

Completed

Biological Signatures, Probiotic Among Those With mTBI and PTSD

Post Traumatic Stress Disorder | Mild Traumatic Brain Injury

United States
Medical University of Graz

Completed

Genomic Signatures to Predict Treatment Response (AGO-Austria)

Breast Neoplasms

Austria
Curatek Pharmaceuticals, LLC

Completed

Multi-Center Study of New Medications to Treat Vaginal Infections (SMART GIVES)

Vaginal Infection

United States
Cairo University

Unknown

Diagnostic Accuracy of Human Transcriptional Activator(MYB) Expression by ELISA Technique Versus Immmunohistochemistry in Detecting Salivary Gland Carcinomas

Malignant Neoplasm of Salivary Gland | Benign Neoplasm of Salivary Gland

Egypt
The Cleveland Clinic
STERIS Corporation

Completed

Effect of the Built Operating Room Environment on Patient Outcome

Anxiety

United States
Side-Out Foundation
Translational Drug Development

Completed

Utilizing Multiomic Advanced Diagnostics to Identify CDK 4/6 Inhibitor Response Predictors and a Post-treatment Multiomic Signature for Patients With ER+/HER2- Metastatic Breast Cancer

Metastatic Breast Cancer

United States
University Hospital, Montpellier
Association Xtraordinaire sub-group DDX3X; Genida

Unknown

Better Delineation of DDX3X Related Phenotype and Epigenetic Signature.

Intellectual Developmental Disorder | X-LINKED

France
Huazhong University of Science and Technology
Zhejiang University; Wuhan Central Hospital

Unknown

Specific Molecular Signatures Predict Neoadjuvant Chemotherapy Response in Cervical Cancer

Cervical Cancer | Uterine Cervical Neoplasms | Uterine Cervical Cancer

China
Novartis Vaccines

Completed

Safety and Immunogenicity of Different Meningitis Vaccine Formulations in Adolescents and Young Adults

Invasive Meningococcal Disease

United States, Poland
Sun Yat-sen University

Unknown

Predictive Value of a mRNA Signature and Liquid Biopsy in Diffuse Large B Cell Lymphoma

Diffuse Large B Cell Lymphoma

China
Chang Gung Memorial Hospital

Completed

Prognostic Utility of the Imaging and Biological Signatures in Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma
Baylor College of Medicine

Completed

Catheter Biofilm Microbiome in Infected Neonatal Catheters.

Catheter-associated Bloodstream Infections (CLABSI)

United States
University of Khartoum
University of York

Completed

Tissue Microenvironment Signatures of the Mycetoma Granuloma

Mycetoma

Sudan
University Hospital, Montpellier

Unknown

Better Delineation of CDK13 Related Phenotype and Epigenetic Signature. (CDK13)

Congenital Heart Defects | Dysmorphic Facial Features and Intellectual Developmental Disorder

France
University Hospital, Montpellier

Unknown

Better Delineation of YY1 Related Phenotype and Epigenetic Signatures.

YY1 Related Disorder

France
Maastricht University
Radboud University Medical Center; University of California, San Francisco

Unknown

CT-based Radiomic Signature Can Identify Adenocarcinoma Lung Tumor Histology

Nonsmall Cell Lung Cancer

Netherlands
MolecuLight Inc.

Unknown

Presence of Fluorescence Signature to Predict Graft Failure Using MolecuLight i:X

Skin Graft (Allograft)(Autograft) Failure

United Kingdom
Josef Smolen, Univ. Prof. Dr.

Unknown

A Study to Target the Type I IFN Receptor by Administrating Anifrolumab in RA Patients With a High IFN Signature (TarIFNiRA)

Rheumatoid Arthritis

Austria
University Hospital Inselspital, Berne

Completed

The Radiation Metabolic Signature of Patient Undergoing Radiotherapy. A Pilot Study

Breast Cancer

Switzerland
Assistance Publique - Hôpitaux de Paris

Unknown

Signature of the Host Response to a Respiratory Viral Infection, in the Prediction of Bronchiolitis Obliterans (ALLOPIV)

Acute Respiratory Infection | Allogeneic Hematopoietic Stem Cell Recipients | Parainfluenza Virus (PIV)

France
Assistance Publique - Hôpitaux de Paris

Unknown

Microbiotic Analysis in Digestive Endocrine Tumors (MicroTEND)

Fecal Microbiota | Digestive Neuroendocrine Tumor | Bacterial Signature
Universiti Putra Malaysia
Universiti Teknologi Mara; Ministry of Health, Malaysia

Unknown

Exploring Nutritype Signature of Type 2 Diabetes Risks in Women Post-Gestational Diabetes Mellitus

Type 2 Diabetes | Gestational Diabetes

Malaysia
Otsuka Pharmaceutical Development & Commercialization...

Terminated

A Trial to Measure the Difference in All-cause Hospitalizations for Participants Who Are Using Abilify MyCite Versus Virtual Matched Controls in Adults With Schizophrenia, Bipolar 1 Disorder, and Major Depressive Disorder

Schizophrenia | Major Depressive Disorder | Bipolar 1 Disorder

United States
Technical University of Munich

Terminated

BOSTRIP: Biomarkers of Systemic Treatment Response in Psoriasis (Bostrip)

Psoriasis

Germany
Cairo University

Completed

Comparative Study Between Nifedipine and Ritodrine as Maintenance Tocolytic Therapy in Preterm Labor

Preterm Birth

Egypt
University Hospital Muenster

Unknown

Signatures of Immune Reprogramming in Anti-CD52 Therapy of MS: Markers for Risk Stratification and Treatment Response (ProgramMS)

Multiple Sclerosis

Germany
University of Michigan

Completed

Character Strengths Intervention Among Psychiatrically Hospitalized Youth

Mental Disorders | Psychiatric Hospitalization | Child/Adolescent Problems
Sergio Polakof
Centre de Recherche en Nutrition Humaine d'Auvergne; Agroscope Liebefeld-Posieux...

Completed

Metabolic Signatures of Dairy Products Ingestion in Humans: Effect of Age (FermentoMilk)

Nutrition

France
Groupe Hospitalier Pitie-Salpetriere

Completed

Sub-study of the NEURODOC Project : Neurophysiological Evaluation of a Routine Care Open Label tDCS Session (Neurodoc)

Stroke | Traumatic Brain Injury | Disorder of Consciousness | Anoxic Brain Injury

France
Novartis Pharmaceuticals

Completed

LEE011 for Patients With CDK4/6 Pathway Activated Tumors (SIGNATURE) (SIGNATURE)

Tumors With CDK4/6 Pathway Activation

United States
Cliniques universitaires Saint-Luc- Université...

Unknown

Development of a Response Signature to Neoadjuvant Chemotherapy for Breast Cancer (Breast-sign)

Breast Cancer

Belgium
Novartis Pharmaceuticals

Terminated

BGJ398 for Patients With Tumors With FGFR Genetic Alterations (CBGJ398XUS04)

Solid Tumor | Hematologic Malignancies

United States
Samsung Medical Center

Completed

Single-arm Study of Selumetinib in Combination With Docetaxel, in Advanced Gastric Adenocarcinoma Patients With Low/High MEK Signature, RAS Mutation or RAS Amplification as a Second-line Chemotherapy

Gastric Adenocarcinoma

Korea, Republic of
PTC Therapeutics

Terminated

PTC299 for Treatment of Advanced Cancer

Advanced Cancer

United States
National Jewish Health
MedImmune LLC

Unknown

Identification of Epidermal Signatures in Patients With Atopic Dermatitis

Atopic Dermatitis

United States
PTC Therapeutics
United States Department of Defense

Terminated

PTC299 for Treatment of Neurofibromatosis Type 2

Neurofibromatosis 2

United States
University of North Carolina, Chapel Hill
National Institutes of Health (NIH)

Completed

Application of a Novel Allergen-Specific Immune Signature Directed Approach to Dietary Elimination Therapy in Patients With Eosinophilic Esophagitis (IDiET) (IDiET)

Eosinophilic Esophagitis

United States
Novartis Pharmaceuticals

Completed

Secukinumab in Tumor Necrosis Factor (TNF) - Inadequate Response (IR) Psoriasis Participants. (SIGNATURE)

Psoriasis

United Kingdom, Ireland
Assistance Publique - Hôpitaux de Paris

Completed

Reverse Transcriptase Inhibitors in AGS (RTIs in AGS)

Aicardi-Goutières Syndrome (AGS)

France
Hospices Civils de Lyon

Completed

BRAN Pilot Study: Metabolic Signature of Wheat Bran Related to Gut Fermentation in Humans (FITABLE)

Healthy

France
Shanghai Zhongshan Hospital
Fudan University; West China Hospital; Guangzhou First People's Hospital; Singlera... and other collaborators

Unknown

Diagnosis of Colorectal Cancer and Advanced Adenoma Using Cancer-specific Methylation Signatures

Colorectal Cancer | Advanced Adenoma

China
Signature Medical, Inc.

Withdrawn

Early Feasibility Study to Assess Safety and Device Performance of AcoustiCare™

Heart Failure，Congestive
Nanfang Hospital of Southern Medical University
Beijing YouAn Hospital; Beijing 302 Hospital; Beijing Shijitan Hospital, Capital... and other collaborators

Completed

Radiomics Signature of Hepatic Venous Pressure Gradient (rHVPG) With CT Angiography (CHESS1701) (rHVPG)

Hypertension, Portal

China

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