Search clinical trials for: efficacy and safety

Total 476568 results

Bio-Thera Solutions

Recruiting

A Multicenter Open Clinical Study of Safety, Tolerability, Pharmacokinetic Profile, and Initial Clinical Efficacy of BAT 8010 for Injection Combined With BAT 1006 in the Treatment of Locally Advanced or Metastatic Tumors

Advanced Solid Tumors

China
Second Affiliated Hospital, School of Medicine,...
Ningbo Medical Center Lihuili Hospital; The Second Affiliated Hospital of Jiaxing... and other collaborators

Not yet recruiting

Real-world Study of Efficacy and Safety of Zonisamide in add-on Therapy for Patients With Focal Epilepsy

Epilepsies, Partial

China
The First Affiliated Hospital with Nanjing Medical...
Zhejiang Cancer Hospital

Recruiting

Efficacy and Safety of Ribociclib in Combination With NSAI Versus Physician's Choice of Chemotherapy Sequential Endocrine Therapy in HR+/HER2- Advanced Breast Cancer

Advanced Breast Cancer

China
Nanfang Hospital, Southern Medical University

Not yet recruiting

A Clinical Study on the Efficacy and Safety of ABCD in the Treatment of Patients With Invasive Fungal Disease

Invasive Fungal Disease
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Efficacy and Safety of Ixekizumab in Patients With Refractory Guttate Psoriasis

Guttate Psoriasis
Swiss Tropical & Public Health Institute
National Institute of Public Health, Vientiane, Laos

Recruiting

Efficacy and Safety of Emodepside in Adults Infected With Strongyloidiasis Stercoralis

Strongyloidiasis | Strongyloides Stercoralis Infection

Lao People's Democratic Republic
Stealth BioTherapeutics Inc.

Recruiting

ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD) (ReNEW)

Age-Related Macular Degeneration

United States
yilong Wang

Recruiting

The Efficacy and Safety of Y-3 Intracalvariosseous Injection Versus Intravenous Injection in the Treatment of Acute Large Hemispheric Infarction (SOLUTION-2)

Stroke, Acute Ischemic | Blood-Brain Barrier

China
EdiGene Inc.
The First Affiliated Hospital of Henan University of Science and Technology; Changping Laboratory

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of ATHENA CAR-T in Subjects With Systemic Lupus Erythematosus

Lupus Erythematosus, Systemic

China
Ting Chang, MD

Not yet recruiting

Safety and Efficacy of CD19-BCMA Targeted CAR-T Therapy for Refractory Generalized Myasthenia Gravis

Myasthenia Gravis

China
Shanghai Children's Medical Center

Not yet recruiting

Comparative Study on the Efficacy and Safety of Ondansetron Oral Membrane for the Prevention of Vomiting During Moderate Hypoemetic Chemotherapy (Ondansetron)

To Analyze and Compare the Efficacy and Safety of Ondansetron and Tablet for the Prevention of Moderate and Hypoemetic Chemotherapy
Sun Yat-sen University

Not yet recruiting

A Randomized Controlled Trial of the Safety and Efficacy of Robotic Telesurgery Versus Laparoscopic Surgery

Rectal Cancer | Renal Cancer | Liver Cancer

China
First Affiliated Hospital of Zhejiang University
Shanghai Longfine Biotechnology Co., Ltd.; TopAlliance

Not yet recruiting

A Study on the Efficacy and Safety of Oral All-trans Retinoic Acid Combined With Toripalimab in TNBC.

Triple-negative Breast Cancer

China
Eilean Therapeutics

Not yet recruiting

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated Relapsed or Refractory Acute Myeloid Leukemia

AML With Gene Mutations

Australia
Potsawat Surabotsopon

Not yet recruiting

Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF : Double Blinded, Randomized Control Trial (MIS-TLIF)

Surgery | Disc Degeneration | Spinal Stenosis Lumbar | Fusion of Spine | Disc Disease
Health Science Center of Xi'an Jiaotong University
Huazhong University of Science and Technology; LinkDoc Technology (Beijing)...

Recruiting

The Study of Huaier Granule in Postoperative Adjuvant Therapy of Resectable Pancreatic Cancer

Pancreatic Cancer Resectable

China
L&C Bio
PROMeDis

Recruiting

Clinical Study to Evaluate the Anti-adhesion Efficacy and Safety of MegaShield®-SP in Comparison With Guardix-SP Plus After Spine Surgery

Herniation, Disc

Korea, Republic of
First Affiliated Hospital of Wenzhou Medical University

Recruiting

Efficacy and Safety of Antiviral Therapy With Peg-interferon for Chronic Hepatitis B Complicated With Nonalcoholic Fatty Liver Disease（OCEAN PROJECT）

Chronic Hepatitis b | Nonalcoholic Fatty Liver Disease

China
The Central Hospital of Lishui City

Not yet recruiting

Efficacy and Safety of DEB-BACE Combined With Serplulimab in First-line Treatment of SCLC

Carcinoma | Small Cell Lung Cancer

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

An Phase III Study, Multicenter，Randomized Controlled Trail to Determine the Safety and Efficacy of the Combination of Tislelizumab With Cisplatin and Gemcitabine, With or Without Trilaciclib for Patients With Untreated Unresectable and Metastatic Urothelial Carcinoma.

Bladder Cancer

China
Peking University People's Hospital

Not yet recruiting

Efficacy and Safety of Anti-CD25 rhMAb in the Treatment of Steroid-Refractory cGVHD

cGVHD
Erasmus Medical Center

Not yet recruiting

Esophageal Self-expandable Metal Stent for Malignant Strictures: a Safety and Efficacy Study (ENTRANCE)

Oesophageal Cancer
Qianfoshan Hospital

Recruiting

Study on the Efficacy and Safety of Conversion Therapy in Patients With Initially Unresectable Hepatocellular Carcinoma

Carcinoma, Hepatocellular

China
Taizhou Mabtech Pharmaceutical Co.,Ltd

Not yet recruiting

To Compare Efficacy and Safety of CMAB007 and Xolair® in Patients With Chronic Spontaneous Urticaria

Chronic Spontaneous Urticaria
The People's Hospital of Gaozhou

Recruiting

The Efficacy and Safety of Dapagliflozin in Improving Heart Failure in Dialysis Patients

The Efficacy and Safety of Dapagliflozin in Improving Heart Failure in Dialysis Patients

China
Editas Medicine, Inc.

Not yet recruiting

A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301

Sickle Cell Disease | Hemoglobinopathies | Transfusion-dependent Beta-Thalassemia
Capital Medical University

Not yet recruiting

Exploratory Study on the Efficacy and Safety of Semaglutide for Idiopathic Intracranial Hypertension Treatment

Idiopathic Intracranial Hypertension
Anhui Provincial Hospital

Not yet recruiting

The Efficacy and Safety of Desensitation Regimen for Patients With High Titers of Anti-HLA Antibodies Prior to Allo-HSCT

High Titers of Anti-HLA Antibody (MFI ≥5000)

China
Hutchmed

Recruiting

A Phase II/III Trial to Evaluate the Efficacy and Safety of Surufatinib Combined With Camrelizumab, Nab-paclitaxel, and Gemcitabine in Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer

China
Rejuva Medical Aesthetics
HealMD, LLC

Not yet recruiting

Evaluating Microneedling With CBD and Hempseed Oil for Acne Vulgaris Safety and Efficacy

Acne Vulgaris (Disorder)

United States
Zhejiang Hanmai Pharmaceutical Technology Co.,...

Not yet recruiting

Multiple-Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of YJ001 for Spray Use in Patients With Diabetic Peripheral Neuropathic Pain

Diabetic Peripheral Neuropathic Pain

United States
Cabaletta Bio

Recruiting

RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia Gravis

Generalized Myasthenia Gravis (gMG)

United States
Byondis B.V.

Recruiting

Safety, Pharmacokinetics, and Preliminary Efficacy of BYON4413 in Acute Myeloid Leukemia and Myelodysplastic Neoplasms.

Relapsed / Refractory AML | Relapsed / Refractory MDS

Spain, Netherlands, Belgium
Shanghai Ark Biopharmaceutical Co., Ltd.

Not yet recruiting

A Study to Evaluate the Efficacy, Safety and Tolerability of Oral AK0901 in Children With ADHD

ADHD

China
Allife Medical Science and Technology Co., Ltd.
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Safety and Preliminary Efficacy of Allogeneic Endothelial Progenitor Cells (EPCs) in Patients With Critical Limb Ischemia

Critical Limb Ischemia

China
Ache Laboratorios Farmaceuticos S.A.

Not yet recruiting

Efficacy/ Safety of DNN.22.17.036 in Male Patients With Pattern Hair Loss (CAPELLI)

Alopecia
Starmed
Helptrial

Not yet recruiting

To Compare and Evaluate the Efficacy and Safety Between TS-RF System and BRK Transseptal Needles Used for Transseptal Puncture for Left Atrial Access.

Heart Diseases | Atrial Fibrillation | Arrhythmias, Cardiac
Sun Jing

Not yet recruiting

A Clinical Study on the Efficacy and Safety of Paclitaxel Polymer Micelles and Cisplatin Combined With Cadonilimab as a Neoadjuvant Therapy for Locally Advanced Esophageal Squamous Cell Carcinoma

Neoadjuvant Therapy | Locally Advanced Esophageal Squamous Cell Carcinoma
RenJi Hospital
Huashan Hospital; First Affiliated Hospital of Zhejiang University; Shenzhen... and other collaborators

Not yet recruiting

Safety and Efficacy of Ventricular Irrigation for Ventriculitis

Central Nervous System Infections

China
Blokhin's Russian Cancer Research Center

Not yet recruiting

A Prospective Clinical Study on the Safety and Efficacy of Radiofrequency Ablation for the Treatment of Patients With Desmoid Tumors (RFAdesmoid)

Desmoid Fibromatosis | Desmoid Tumor | Desmoid

Russian Federation
Vedic Lifesciences Pvt. Ltd.

Recruiting

A Study for Assessing the Efficacy and Safety ParActin® in Individuals With Upper Respiratory Tract Infections

Upper Respiratory Tract Infections

India
Merck Sharp & Dohme LLC
Orion Corporation, Orion Pharma

Recruiting

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

Prostatic Neoplasms, Castration-Resistant

Israel, Taiwan, Australia, Korea, Republic of
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

A Study to Evaluate the Efficacy and Safety in Subjects With Advanced Breast Cancer Treated With SYHX2011

Advanced Breast Cancer

China
Tang Ziren

Not yet recruiting

Butylphthalide's Safety and Efficacy for Improving Neurological Function Prognosis in Patients With Cardiac Arrest (BNCA Trial)

Cardiac Arrest | Butylphthalide | Neuroprotective Drugs

China
Ferrer Internacional S.A.

Recruiting

A Study to Assess the Efficacy, Safety, and Pharmacokinetics of FNP-223 to Slow Progression of Progressive Supranuclear Palsy (PSP)

Progressive Supranuclear Palsy

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Efficacy and Safety of Angiotensin II Injection Versus Placebo in Patients With Refractory Distributed Shock

Vasodilatory Shock

China
InnoCare Pharma Inc.

Not yet recruiting

Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ICP-248 in Mature B-cell Malignancies

Mature B-cell Malignancies
Richard Frye

Not yet recruiting

Safety and Efficacy of tPBM for Epileptiform Activity in Autism (tPBM)

Epilepsy | Neurodevelopmental Disorders | Autism Spectrum Disorder | Neurological Disorder | EEG With Periodic Abnormalities

United States
Tufts University
Guangdong Bixdo Health Technology Co., Ltd.

Not yet recruiting

Evaluation of Safety and Efficacy of Bixdo Ultra Compact Water Flosser

Plaque Induced Gingivitis

United States
920th Hospital of Joint Logistics Support Force...

Recruiting

Efficacy and Safety of CAR-T Cells Therepy for Chronic or Refractory Primary Immune Thrombocytopenia (ITP)

ITP - Immune Thrombocytopenia

China

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