Search clinical trials for: incretins

Total 1804 results

The Cleveland Clinic

Active, not recruiting

EMI-EHP Weight Management and Type 2 Diabetes Pragmatic Trial (EMPOWER-T2D)

Obesity | Type 2 Diabetes

United States
Oregon Health and Science University

Suspended

Effects of DPP-4 Inhibition on Triglycerides

Type 2 Diabetes | Hypertriglyceridemia

United States
Genuine Research Center, Egypt
Eva Pharma

Completed

Bioequivalence Study of of Metformin HCl From Gleptomet 50/1000 mg F.C.Tablets (EVA Pharma, Egypt) and Janumet 50/1000 mg F.C.Tablets (Merck Sharp & Dohme, The Netherlands)

Healthy

Egypt
Eli Lilly and Company

Completed

A Study of the Effect of Tirzepatide on How the Body Handles Birth Control Pills in Healthy Female Participants

Healthy

United States
Eli Lilly and Company

Completed

A Study of Tirzepatide in Participants With Impaired Liver Function

Hepatic Insufficiency

United States
Eli Lilly and Company

Completed

Study of Tirzepatide in Healthy Participants

Healthy

United Kingdom
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) in Participants With Impaired Kidney Function

Renal Insufficiency | End Stage Renal Disease

United States
Shenzhen Salubris Pharmaceuticals Co., Ltd.

Completed

SAL067 Treatment in Patients With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise

Diabetes Mellitus, Type 2

China
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) in Japanese Participants With Type 2 Diabetes

Type 2 Diabetes Mellitus

Japan
Eli Lilly and Company

Completed

A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus (T2DM)

Diabetes Mellitus, Type 2

Germany
James J. Peters Veterans Affairs Medical Center
Kessler Institute for Rehabilitation

Completed

Once Weekly GLP-1 in Persons With Spinal Cord Injury

Obesity | Insulin Resistance | Spinal Cord Injuries | Pre Diabetes

United States
University of Maryland, Baltimore

Terminated

Pharmacogenomics of GLP1 Receptor Agonists

Type 2 Diabetes

United States
Assistance Publique - Hôpitaux de Paris
Assistance Publique Hopitaux De Marseille; Institut National de la Santé Et... and other collaborators

Active, not recruiting

Incretin-mimetic Hypoglycemic Drugs and Severe Retinopathy (ANGIOSAFE2)

Type 2 Diabetes

France
David Sanchez Garcia
Instituto Mexicano del Seguro Social

Completed

Effect of Liraglutide on Subclinical Atherosclerosis in Patients With Type 1 Diabetes Mellitus

Diabetes Mellitus, Type 1

Mexico
Eli Lilly and Company

Completed

A Study of LY3537021 in Healthy Participants

Healthy

Singapore
Hua Medicine Limited

Completed

Drug Interaction Study Between Dorzagliatin and Sitagliptin

Patients

United States
University of Leeds

Completed

Targeting Beta-cell Failure in Lean Patients With Type 2 Diabetes (Lean-DM)

Diabetes Mellitus, Type 2

United Kingdom
University at Buffalo
Kaleida Health

Completed

The Effect of LINAGLIPTIN on Inflammation, Oxidative Stress and Insulin Resistance in Obese Type 2 Diabetes Subjects (1971)

Type 2 Diabetes

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

GLP-1 Agonism for Blocking Cocaine Euphoria and Self-Administration

Cocaine Dependence

United States
Erasme University Hospital

Terminated

Pathophysiological Study of the Increase in Pancreatic Volume in Type 2 Diabetes Treatments.

Type 2 Diabetes | Pancreas | Incretinomimetics

Belgium
Novo Nordisk A/S

Withdrawn

INSPIRE Turkey :A Research Study Looking at the Clinical Parameters Associated With Use and Discontinuation of Saxenda® in Local Clinical Practice in Turkey by Analysing Past Patient Medical Records (INSPIRE Turkey)

Obesity

Turkey
Novo Nordisk A/S

Completed

In-market Utilisation of Liraglutide Used for Weight Management in Europe

Obesity | Metabolism and Nutrition Disorder

Italy, Germany
George Washington University
Boehringer Ingelheim

Completed

Linagliptin's Effect on CD34+ Stem Cells

Type 2 Diabetes | Impaired Renal Function

United States
Celltrion

Completed

A Bioequivalence Study of CT-L01 Compared to Co-administration (ALO 12.5 mg and MET XR 500 mg) in Healthy Volunteers

Healthy

Korea, Republic of
Celltrion

Completed

A Bioequivalence Study of CT-L01 Compared to Co-administration (ALO 25 mg and MET XR 1,000 mg) in Healthy Volunteers

Healthy

Korea, Republic of
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes on Metformin With or Without Sulfonylurea (SURPASS-AP-Combo)

Type 2 Diabetes

China, Australia, Korea, Republic of, India
Washington University School of Medicine
Merck Sharp & Dohme LLC

Completed

Efficacy Study of Sitagliptin to Prevent New-onset Diabetes After Kidney Transplant

Posttransplant Diabetes Mellitus

United States
VA Office of Research and Development
Durham VA Medical Center

Completed

Regulation of Insulin Secretion by the GLP-1 Receptor

Insulin Secretion

United States
Novo Nordisk A/S

Completed

A Trial Comparing Insulin Degludec/Liraglutide, Insulin Degludec, and Liraglutide in Chinese Subjects With Type 2 Diabetes Inadequately Controlled on Oral Antidiabetic Drugs (OADs) (DUAL™ I China)

Diabetes Mellitus, Type 2 | Diabetes

China
Sichuan Haisco Pharmaceutical Group Co., Ltd

Completed

HSK7653 Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

China
NYU Langone Health
Novo Nordisk A/S

Completed

Clinical Efficacy and Safety of Using 3.0mg Liraglutide to Treat Weight Regain After Roux-en-Y Gastric Bypass Surgery

Obesity

United States
Yale University

Completed

Effect of Liraglutide on Neural Responses to High Fructose Corn Syrup in Individuals With Obesity.

Obesity, Childhood | Neural Development

United States
Novo Nordisk A/S

Completed

Timely Detection of Treatment Emergent Serious and Non-serious Adverse Events for Saxenda® in Mexican Patients

Obesity

Mexico
Novo Nordisk A/S

Completed

In Market Utilisation of Liraglutide Used for Weight Management in the UK: a Study in the CPRD Primary Care Database

Obesity | Overweight

Denmark
Novo Nordisk A/S

Completed

A Research Study About Weight Loss and Treatment Patterns With the Use of Saxenda® in Adults in Real-life Settings in Switzerland

Obesity or Overweight

Denmark
Icahn School of Medicine at Mount Sinai
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Withdrawn

Mechanisms Underlying Predictors of Success From Obesity Surgery

Obesity

United States
Novo Nordisk A/S

Completed

Glycaemic Control and Other Clinical Parameters in Adult Type 2 Diabetes Patients on Basal Insulin Initiating Treatment With IDegLira in Routine Clinical Practice in Colombia (SPIRIT)

Diabetes Mellitus, Type 2

Colombia
University of Pisa

Completed

Effects of Dapagliflozin+Saxagliptin in Addition to Metformin v/s Saxagliptin or Dapagliflozin in Patients With DM2.

Type2 Diabetes Mellitus

Italy
University Health Network, Toronto
Novo Nordisk A/S

Enrolling by invitation

Semaglutide vs Sitagliptin

Diabetes Mellitus | NAFLD | NASH - Nonalcoholic Steatohepatitis | Liver Transplant; Complications

Canada
Novo Nordisk A/S

Withdrawn

A Research Study Looking at Blood Sugar Control in People With Type 2 Diabetes Previously Treated With Premix Insulin and Initiating Treatment With Insulin Degludec/Liraglutide (IDegLira) in Local Clinical Practice in Croatia (GLIDE)

Diabetes Mellitus, Type 2
Mayo Clinic

Completed

Assess the Efficacy and Safety of Exenatide SR for the Prevention of Diabetes After Kidney Transplantation

Pre Diabetes

United States
SK Chemicals Co., Ltd.

Completed

A Pharmacokinetic Study of SID1903 (FDC of Dapagliflozin and Sitagliptin) in Healthy Adult Volunteers

Healthy Subjects

Korea, Republic of
Takeda
Takeda Development Center Americas, Inc.

Completed

Phase 3 Alogliptin Pediatric Study

Diabetes Mellitus, Type 2

United States, Italy, Mexico, Russian Federation, Brazil, Israel, Poland
Vanderbilt University Medical Center
American Heart Association

Completed

Cardiovascular Effects of GLP-1 Receptor Activation

Obesity | PreDiabetes

United States
Peking Union Medical College Hospital

Active, not recruiting

[68Ga]Ga-HBED-CC-exendin-4 and [68Ga]Ga-NOTA-exendin-4 PET/CT Imaging in the Same Group of Insulinoma Patients

Insulinoma

China
University at Buffalo
Amylin Pharmaceuticals, LLC.

Completed

Exeantide in Type 2 Diabetes on Insulin

Type 2 Diabetes

United States
Seoul National University Bundang Hospital
Astellas Pharma Korea, Inc.

Completed

Efficacy of Ipragliflozin Compared With Sitagliptin in Uncontrolled Type 2 Diabetes With Sulfonylurea and Metformin

Type 2 Diabetes Mellitus

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

A Pooled Analysis of the Safety and Efficacy of MK-0431A and MK-0431A XR in Pediatric Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Therapy (Alone or in Combination With Insulin) (MK-0431A-170/MK-0431A-289)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

Study to Assess Safety & Efficacy of Sitagliptin as Initial Oral Therapy for Treatment of Type 2 Diabetes Mellitus in Pediatric Participants. (MK-0431-083)

Diabetes Mellitus | Type 2 Diabetes
Galenicum Health

Completed

Comparative Bioavailability Study of Sitagliptin/Metformin 50 mg/1000 mg Tablets in Healthy Male and Female Volunteers

Type 2 Diabetes | Bioequivalence

Canada

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