Search clinical trials for: lysine demethylase 1 (LSD1) inhibition

Total 49013 results

University of Washington
National Center for Advancing Translational Sciences (NCATS)

Not yet recruiting

Parenting Support for Justice Involved Families

Parenting | Mental Health Wellness 1 | Well-Being, Psychological
University of Southern Denmark
University of Copenhagen

Completed

Acute Effects of Physical Activity On Memory, Cognitive Performance and Brain Activity

Mental Health Wellness 1

Denmark
University of Teramo
DAngelino

Completed

Dietary Habits and Lifestyle of Nonagenarians and Centenarians in the Italian Abruzzo Region

Diet Habit | Fasting | Activity, Motor | LONGEVITY 1

Italy
King's College London

Completed

MeT4VeT: Mental Health Toolkit for Military Veterans Trial

Mental Health Wellness 1 | Mental Health Issue

United Kingdom
Psychiatric University Hospital, Zurich
University of Basel

Completed

Neurodynamics of Prosocial Emotional Processing Following Serotonergic Stimulation With N,N-Dimethyltryptamine (DMT) and Harmine in Healthy Subjects

Emotions | Mood | Cognitive Function 1, Social | Empathy

Switzerland
University of South Wales
British Red Cross

Withdrawn

A Mental Health Social Prescribing Trial (British Red Cross) (PROSPECT)

Mental Health Wellness 1

United Kingdom
Janssen Pharmaceutica N.V., Belgium

Completed

Study to Assess the Acceptability of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Fixed-Dose Combination (FDC) Tablets in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Pediatric Participants, Using Matching Placebo Tablets

HIV-1

United States, Spain
Merck Sharp & Dohme LLC

Completed

A Study of Islatravir (MK-8591) in Anti-Retroviral Therapy-Naive, Human Immunodeficiency Virus-1 Infected Participants (MK-8591-003)

HIV-1
Janssen Research & Development, LLC

Completed

Study to Assess the Acceptability/Swallowability of DRV-Containing FDC Tablets in HIV-1 Infected Adolescents, Using Matching Placebo Tablets

HIV-1

United States
Janssen-Cilag Ltd.

Completed

Early Access to Low-dose Ritonavir (TMC114/r) and Other Antiretrovirals (ARVs) for Treatment-naive or Early Treatment Experienced in HIV-1 Patients

HIV-1

Taiwan
Bristol-Myers Squibb

Completed

Korean Post-marketing Surveillance for Reyataz®

HIV-1

Korea, Republic of
Ratiopharm GmbH

Completed

Multiple Dose BE Study With Nevirapine 400mg PR Tablets

HIV-1

United Kingdom
Fundacion para la Investigacion Biomedica del Hospital...
Pfizer

Completed

Effect Of A CCR5 Coreceptor Antagonist On The Latency And Reservoir Of HIV-1

HIV-1

Spain
Pfizer
ViiV Healthcare

Completed

A Study in Asymptomatic HIV Infected Patients to Investigate Pharmacodynamics, Pharmacokinetics, Safety and Toleration of UK-453,061

HIV-1

Germany
ViiV Healthcare
Pfizer

Completed

Trial of Maraviroc (UK-427,857) in Combination With Zidovudine/Lamivudine Versus Efavirenz in Combination With Zidovudine/Lamivudine (MERIT)

HIV-1

United States, Canada, United Kingdom, Netherlands, Argentina, Australia, Belgium, South Africa, Switzerland, Italy, Puerto Rico, Brazil, Mexico, Poland
Gilead Sciences

Completed

ROCKET II - Randomized Open Label Switch for Cholesterol Elevation on Kivexa + Kaletra Evaluation Trial (ROCKET II)

HIV-1

Austria, Germany, Italy, Spain
Swedish Institute for Infectious Disease Control
The Swedish Research Council; European Union; Läkare mot AIDS Forskningsfond

Completed

Dermal HIV-1 Immunization During Anti-retroviral Therapy Followed by Repeated Treatment Interruptions (Vac09)

HIV-1

Sweden
Eunice Kennedy Shriver National Institute of Child...

Completed

Interventions to Decrease the Risk of Mother-to-Child Transmission of HIV in India

HIV-1

United States
Eli Lilly and Company

Not yet recruiting

Lebrikizumab Pen Ease of Use in Participants With Atopic Dermatitis

Atopic Dermatitis

United States
Andrzej Frycz Modrzewski Krakow University
Karolinska Institutet; University of Rzeszow

Completed

Polish Validation 4AT Tool

Delirium, Postoperative | Surgical Procedure

Poland
Activ'inside
CIC Inserm 1405, University Hospital Clermont-Ferrand, France

Completed

Bioavailabity of the Major Metabolites of a Botanical Extract, in Healthy Adults

Healthy

France
Rajesh Deshar

Completed

Effect of Glycopyrrolate on Vasopressors Requirement for Non-elective Caesarean Section Under Spinal Anaesthesia

Hemodynamic Instability | Effect of Drug | Post-spinal Hypotension | Glycopyrrolate

Nepal
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Completed

A Study to Evaluate the Effect of a Dual CYP2C19 and CYP3A4 Inhibitor, Fluconazole, on the Pharmacokinetics of Fedratinib in Healthy Adult Subjects

Healthy Volunteers

United States
DiaSorin Inc.
ICON Clinical Research

Completed

Helicobacter Pylori Sample Collection Protocol Post Therapy Subjects

Nausea | Abdominal Pain | Weight Loss | Helicobacter Pylori Infection | Gastric Ulcer | Stomach Ulcer | Loss of Appetite | Bloating

United States, Italy
Hacettepe University

Not yet recruiting

Body Awareness and Mental Fatigue in Neck Pain

Mental Fatigue | Neck Pain | Mindfulness | Awareness

Turkey
Hacettepe University

Completed

Comprehensive Evaluation in Patients With Meniere's Disease

Quality of Life | Physical Disability | Psychosocial Problem | Meniere Disease

Turkey
National University Hospital, Singapore
Natera, Inc.; The N.1 Institute for Health (N.1)

Recruiting

Nivolumab and Pembrolizumab Dose Optimisation in Solid Tumours With CURATE.AI Platform and Sequential ctDNA Measurements

Solid Tumor

Singapore
Institute of Child Health
Great Ormond Street Hospital for Children NHS Foundation Trust

Not yet recruiting

Exploring Bulbar Function, Speech And Communication Development in SMA Type 1 (ExSpAnD SMA)

SMA1
St. Mary's University, Twickenham

Recruiting

Caffeine, DNA and Cognition

Cognitive Function 1, Social

United Kingdom
University of New Mexico

Completed

Developing Community Partnerships Through Research to Define Community Well-Being With Three (Diné) Navajo Communities

Mental Health Wellness 1 | Behavior, Health | Community

United States
Nanyang Technological University
National Gallery Singapore

Enrolling by invitation

Slow Art Plus: A Single Session Art Gallery-based Intervention for Mental Health Promotion (SAP)

Compassion | Mental Health Wellness 1 | Self Care

Singapore
ANRS, Emerging Infectious Diseases
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Completed

Prevention of Mother-to-child Transmission of HIV-1 Using a Responsive Intervention (PROMISE-EPI)

HIV-1

Burkina Faso, Zambia
University of Electronic Science and Technology...

Unknown

Sex- and Context-dependent Effects of Oxytocin on Social Reward Processing

Mental Health Wellness 1 | Social Behavior | Emotion

China
Hospital Universitari Vall d'Hebron Research Institute
Gilead Sciences

Completed

Evolution of Plasma Lipid Profile in Patients With HIV1 Who Change Atripla to Eviplera Compared to Continue With Atripla

HIV-1

Spain
Hospital Universitari Vall d'Hebron Research Institute
University Hospital, Ghent; IrsiCaixa

Completed

HIV Reservoir Dynamics After Switching to Dolutegravir in Patients on a PI and 2 NRTI Based Regimen

HIV-1

Spain
Gilead Sciences

Completed

Peripheral Body Fat Distribution After Switching Zidovudine and Lamivudine to Truvada (RECOMB)

HIV-1

Spain
University of Aarhus
Aarhus University Hospital Skejby; Bandim Health Project; Abbott; Ministry of Health...

Completed

PI or NNRTI as First-line Treatment of HIV in West Africa - the PIONA Trial (PIONA)

HIV-1

Guinea-Bissau
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-TiDP35-C213: Safety and Antiviral Activity of Etravirine (TMC125) in Treatment-Experienced, HIV Infected Children and Adolescents

HIV-1

United States, France, Spain, Portugal, Canada, United Kingdom, South Africa, Argentina, Brazil, Puerto Rico, Thailand, Netherlands, Romania
Tibotec Pharmaceuticals, Ireland

Completed

An Open-label Trial With TMC125 in Patients Who Have Virologically Failed in a DUET Trial (TMC125-C206 or TMC125-C216).

HIV-1

United States, Canada, France, Belgium, Germany, Spain, Argentina, Chile, Panama, Brazil, Puerto Rico, Thailand, Mexico, Australia
Mymetics Corporation
Institut Cochin; San Raffaele University Hospital, Italy; Kinesis Pharma B.V.; ... and other collaborators

Completed

Investigation of the Safety of an HIV-1 Vaccine Given Intra-muscularly and Intra-nasally to Healthy Female Subjects

HIV-1

Belgium
Ono Pharmaceutical Co. Ltd

Active, not recruiting

Study of ONO-4578 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid Tumors

Advanced or Metastatic Solid Tumors

Japan
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

A Study Comparing Irinotecan and Cisplatin (IP) With Etoposide and Cisplatin (EP) Following EP/TRT for LD-SCLC

Small-Cell-Lung Cancer

Japan
Lixia Sheng

Recruiting

Clinical Study of OR for Second-line Treatment of Refractory MZL

OR Regimen for Relapsed/Refractory Marginal Zone Lymphoma

China
Eli Lilly and Company

Active, not recruiting

A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants With Type 2 Diabetes (SURPASS-EARLY)

Type 2 Diabetes

United States, United Kingdom, Germany, Mexico, Romania, Argentina, Canada, Puerto Rico, Israel, Italy, Slovakia
Istanbul Demiroglu Bilim University

Not yet recruiting

Delirium Prevention Guideline for Intensive Care Patients

Delirium | Nurse's Role

Turkey
Gamze Akay
Artvin Coruh University

Not yet recruiting

The Effect of Reading a Pictorial Storybook on Children's Fear, Anxiety and Emotional Symptoms Before Dental Treatment

Dental Fear

Turkey
University of Florence

Completed

Oral Contraceptive Therapy and Sexuality (COSEX)

Mental Health Wellness 1 | Sexual Behavior | Contraceptive Usage

Italy
Pfizer

Terminated

A Phase 2B Multicenter, Randomized, Comparative Trial Of UK-453,061 Versus Etravirine In Combination With Darunavir/Ritonavir And A Nucleos(t)Ide Reverse Transcriptase Inhibitor For The Treatment Of Antiretroviral Experienced HIV-1 Infected Subjects With Evidence Of NNRTI Resistant HIV-1

HIV-1

Spain, United Kingdom, Malaysia, United States, Portugal, Brazil, Germany, Italy, Poland, Puerto Rico, South Africa, Taiwan, Ukraine
University of Oxford
Medical Research Council

Terminated

Safety and Immunogenicity of MVA.HIVconsv in HIV-1 Seropositive Adults on HAART

HIV-1

United Kingdom
Christoph Stephan
University Hospital Heidelberg

Completed

Impact of Raltegravir on HIV-1 cDNA Slope Following Antiretroviral Therapy (ART) Initiation

HIV-1

Germany

Search clinical trials for: lysine demethylase 1 (LSD1) inhibition

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