Search clinical trials for: nucleoside analogues

Total 455 results

Cliniques universitaires Saint-Luc- Université...
Belgian Study Group for Pediatric Endocrinology

Unknown

Long-term Outcome of GnRH Analogues Treatment of Children With Idiopathic Central Precocious Puberty

Puberty, Precocious | Adiposity

Belgium
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

Incretin-based Drugs and the Risk of Heart Failure

Type 2 Diabetes Mellitus

Canada
Tibotec Pharmaceuticals, Ireland

Completed

TMC278-TiDP6-C215: A Clinical Trial in Treatment Naive HIV-subjects Patients Comparing TMC278 to Efavirenz in Combination With 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors

HIV Infections | HIV-1

United States, France, United Kingdom, China, Belgium, Germany, Spain, Chile, Mexico, Portugal, Costa Rica, Panama, South Africa, Canada, Brazil, Puerto Rico, Russian Federation, Thailand, Australia, India
Tibotec Pharmaceuticals, Ireland

Completed

TMC278-TiDP6-C209: A Clinical Trial in Treatment Naive HIV-1 Patients Comparing TMC278 to Efavirenz in Combination With Tenofovir + Emtricitabine.

HIV Infections | HIV-1 | Human Immunodeficiency Virus Type 1

United States, Australia, France, United Kingdom, Taiwan, Spain, Argentina, Portugal, Romania, South Africa, Canada, Denmark, Sweden, Netherlands, Brazil, Puerto Rico, Austria, Russian Federation, Thailand, Mexico
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

Incretin-based Drugs and Pancreatic Cancer

Diabetes Mellitus, Type 2

Canada
AHS Cancer Control Alberta

Terminated

Cisplatin, Carboplatin, and Oxaliplatin Interactions With Plasma Proteins

Colorectal Cancer | Lung Cancer

Canada
Rigshospitalet, Denmark
University of Copenhagen

Completed

Backup With Combivir or Single Dose (SD) Truvada in Order to Avoid Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI) Resistance After SD Nevirapine for the Prevention of Mother-to-child Transmission (PMTCT)

HIV Infections

Tanzania
The First Affiliated Hospital of Guangzhou Medical...

Unknown

Lingdancao Granules in the Treatment of Seasonal Influenza

Influenza
Yale University
Bristol-Myers Squibb; Merck Sharp & Dohme LLC

Completed

Pilot Study of a Raltegravir Based NRTI Sparing Regimen

HIV Infections | Human Immunodeficiency Virus | AIDS | Acquired Immune Deficiency Syndrome

United States
Duke University
Genzyme, a Sanofi Company

Completed

How Vitamin D Analogues Affect Endothelial Cells in Patients on Dialysis

Kidney Failure, Chronic | Hyperparathyroidism, Secondary

United States
VA Puget Sound Health Care System
Novartis Pharmaceuticals; University of Washington

Completed

Innate Immune Response in COPD

Inflammation | Pulmonary Disease, Chronic Obstructive | Bronchitis, Chronic | Immunity, Innate | Toll-Like Receptors

United States
Gilead Sciences

Completed

Study to Evaluate Switching From Regimens Consisting of a Ritonavir-boosted Protease Inhibitor (PI) and Two Nucleoside Reverse Transcriptase Inhibitors (NRTIs) to a Fixed-dose Tablet Containing Emtricitabine/Rilpivirine/Tenofovir DF

HIV-1 Infection

United States, Spain, United Kingdom, Canada, Puerto Rico, France, Belgium, Italy, Germany, Austria
University of Aarhus

Completed

Surgical Versus Medical Treatment of Acromegaly

Acromegaly

Denmark
Instituto de Investigacion Sanitaria La Fe

Completed

The Effect of Pre-treatment With GnRH Analogues Prior in Vitro Fertilization in Patients With Endometriosis (ENDOFIV)

Infertility | Endometriosis

Spain
Medical College of Wisconsin

Completed

Placental and Cord Blood Markers Associated With Premature Birth and Disorders of Premature Birth in Newborn Infants

Premature Birth

United States
UMC Utrecht
European Association of Cardiothoracic Anaesthesiologists

Completed

Inflammatory Response During Anesthesia and Surgery (IRAS)

Myocardial Ischemia | Systemic Inflammatory Response Syndrome

Netherlands
Vancouver Infectious Diseases Centre
Gilead Sciences; Regina General Hospital

Unknown

STRIBILD in Non-Nucleoside Resistant Patients (SINNR STUDY) (SINNR)

HIV | Illicit Drug User

Canada
University Health Network, Toronto

Unknown

Sustained Off-treatment Response After HBeAg Loss in Chronic Hepatitis B Patients Treated With Nucleos(t)Ide Analogues (Stop)

Chronic Hepatitis B

Canada
University of Minnesota
Merck Sharp & Dohme LLC

Withdrawn

Raltegravir Activity In Lymphoid Tissues

HIV Infections | HIV Infection

United States
Asan Medical Center
Novartis Korea Ltd.

Unknown

Hormonal Outcomes in Acromegalic Patients With Treated Surgery With or Without Long Acting Somatostatin Analogues (acromegaly)

Acromegaly

Korea, Republic of
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

A Study to Evaluate the Pharmacokinetic Profile (How the Body Absorbs, Distributes, Metabolizes and Eliminates a Drug) of TMC125 Plus Tenofovir/Emtricitabine Once Daily With or Without Darunavir/r Once Daily in Antiretroviral (ARV) Naive HIV-1 Patients (Patients Have Never Received ARV Treatment).

HIV-1 Infection
The HIV Netherlands Australia Thailand Research...
Chulalongkorn University; Khon Kaen University

Completed

PK TDF in Thai HIV-infected Children

HIV

Thailand
LEO Pharma

Completed

An Irritation Study With New Calcipotriol Ointment Formulations in Healthy Subjects

Irritation

France
M.D. Anderson Cancer Center

Completed

Clofarabine in Chronic Lymphocytic Leukemia

Lymphoproliferative Disorders | Leukemia | Hematologic Neoplasms | Leukemia, Lymphocytic, Chronic

United States
USDA, Western Human Nutrition Research Center
U.S. Highbush Blueberry Council

Completed

The Effects of Antioxidants in Blueberry Powder on Inflammation Induced by a Single High Fat Meal. (FL89)

Inflammation

United States
Medical University of Vienna

Completed

On the Impact of Therapeutic Tumor Necrosis Factor-alpha Inhibition on Anogenital Human Papillomavirus Infection

Inflammatory Bowel Diseases | Psoriasis
Central Institute of Mental Health, Mannheim

Completed

Processing of Salient Emotional Stimuli as a Function of Tetrahydrocannabinol (THC) and Cannabidiol (CBD) (AB_THC_CBD)

Healthy Humans

Germany
Steen Andersen
Medtronic

Completed

Effect of CSII and CGM on Progression of Late Diabetic Complications

Type 1 Diabetes Mellitus

Denmark
Vanderbilt University
Sanofi

Completed

Insulin Exposure and Glucose Response to Meals in Type 1 Diabetic Subjects Administered Two Different Insulin Regimens Compared to the Endogenous Insulin Exposure and Glucose Response to Meals In Healthy Adult Controls

Type 1 Diabetes
Jia Fan
SciClone Pharmaceuticals

Unknown

Thymalfasin Adjuvant Therapy in Hepatitis B Virus (HBV)-Related Hepatocellular Carcinoma (HCC) After Curative Resection

Curable Hepatitis B Virus-Related Hepatocellular Carcinoma

China
Pusan National University Hospital

Unknown

HBsAg Decline After Pegylated-interferon-α in e Antigen Positive Chronic Hepatitis B With Nucleoside Maintenance

Chronic Hepatitis B

Korea, Republic of
Universidad Nacional de Asunción

Completed

Basal Bolus Versus Human Insulin in Hospitalized Patients With Diabetes in Paraguay

Hyperglycemia | Diabetes

Paraguay
Boehringer Ingelheim

Completed

Effects of Tipranavir/Ritonavir on the Pharmacokinetic Characteristics of Triple Drug Nucleoside and Non-nucleoside Reverse Transcriptase Inhibitor Therapy in HIV-1-infected Subjects

HIV Infections
Boehringer Ingelheim

Terminated

Tipranavir and Ritonavir vs. Saquinavir and Ritonavir Used With Two Nucleoside Reverse Transcriptase Inhibitors in Single Protease Inhibitor-experienced HIV-1 Patients

HIV Infections
Boehringer Ingelheim

Completed

Exploratory Study of Tipranavir and Ritonavir in Multiple Protease Inhibitor-experienced HIV Patients

HIV Infections
Boehringer Ingelheim

Completed

Study to Determine the Antiviral Activity and Safety of Alovudine in Nucleoside-experienced HIV-infected Subjects Experiencing Virologic Failure

HIV Infections
Clovis Oncology, Inc.

Completed

Safety and Pharmacokinetic Profiles of Two Formulations of CO-1.01 in Patients With Advanced Solid Tumors

Advanced Solid Tumor

Netherlands
Boehringer Ingelheim

Completed

Observational Study With Antiretroviral Treated Patients Switching to Nevirapine Plus Two Nucleoside Reverse Transcriptase Inhibitor (NRTI) Regimens

HIV Infections
Boehringer Ingelheim

Completed

Impact of Switching to NNRTI-based Therapy on the Quality of Life of HIV-infected Patients With Virological Suppression

HIV Infections
Boehringer Ingelheim

Terminated

Investigation of the Potential Pharmacokinetic Interaction Between Nevirapine, Abacavir and Amprenavir in HIV-1 Infected Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Naive Adults

HIV Infections
Radboud University Medical Center
Ipsen

Completed

Somatostatin Analogues as a Volume Reducing Treatment of Polycystic Livers (RESOLVE) (RESOLVE)

Polycystic Liver Disease

Netherlands
Boehringer Ingelheim

Terminated

SPRING: Safety, Efficacy, Pharmacokinetics of tipRanavir/r IN Race/Gender HIV+ Patients Randomized to TDM or SoC

HIV Infections

United States, Argentina, Brazil, Canada, Germany, Italy, Spain
Tibotec Pharmaceuticals, Ireland

Completed

A Study of TMC278 in Human Immunodeficiency Virus Type 1 Infected Patients, Who Are Not Treated With Antiretroviral Medicines

Human Immunodeficiency Virus Type 1

United States, France, United Kingdom, China, Germany, South Africa, Russian Federation, Argentina, Brazil, Puerto Rico, Austria, Thailand, Mexico, Uganda
Nanfang Hospital of Southern Medical University
Major Science and Technology Special Project of China Eleventh Five-year

Unknown

Efficacy Optimizing Extension Study of Chronic Hepatitis B Patients With Inadequate Response to NUC Therapy (Dragon-Ex)

Chronic Hepatitis B | Inadequate Response | Nucleos(t)Ide Analogues Treatment

China
M.D. Anderson Cancer Center
Access Pharmaceuticals, Inc.

Completed

4'-Thio-araC (Thiarabine) in Advanced Hematologic Malignancies

Leukemia

United States
Clovis Oncology, Inc.

Completed

A Study Comparing CO-1.01 With Gemcitabine as First Line Therapy in Patients With Metastatic Pancreatic Adenocarcinoma (LEAP)

Metastatic Pancreatic Adenocarcinoma

United States, Belgium, Canada, Australia, United Kingdom, Germany, Italy, Argentina, Russian Federation, France, Brazil, Sweden, Norway, Netherlands, Ukraine
University of Miami

Completed

Eyelash Growth From Application of Bimatoprost in Gel Suspension to the Base of the Eyelashes

Hypertrichosis

United States
Italfarmaco

Completed

A Two Part Phase 1, Repeated Doses and Continuous Infusion Study With ITF2984 in Healthy Volunteers (14 days MAD)

Healthy

Italy
Clovis Oncology, Inc.

Terminated

A Dose Ascending Study of Gemcitabine Elaidate (CO-101) in Combination With Cisplatin

Lung Cancer | Solid Tumor | Non-small-cell Lung Cancer

United States, United Kingdom
Novartis Pharmaceuticals

Completed

A 6-month, Randomized, Open-label, Patient OutComes, Safety and Tolerability Study of Fingolimod (FTY720) 0.5 mg/Day vs. Comparator in Patients With Relapsing Forms of Multiple Sclerosis (EPOC)

Relapsing Forms of Multiple Sclerosis

United States, Canada, Puerto Rico

Search clinical trials for: nucleoside analogues

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Portugal

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations