Search clinical trials for: tissue plasminogen activator

Total 62159 results

Vanderbilt University Medical Center
National Center for Research Resources (NCRR)

Completed

Diurnal Variation of Plasminogen Activator Inhibitor-1

Metabolic Syndrome X

United States
Cerevast Medical, Inc.

Unknown

Aureva Transcranial Ultrasound Device With tPA in Patients With Acute Ischemic Stroke (TRUST)

Acute Ischemic Stroke

United States
Centre Hospitalier Universitaire, Amiens

Completed

Determination of the RANKL/Osteoprotegerin Ratio in Patients With Systemic Lupus Erythematosus. Role in Osteoporosis and Cardiovascular Calcification (CALCILUP)

Lupus Erythematosus, Systemic | Osteoporosis

France
Pfizer

Completed

Study to Assess the Concentration of Avibactam and Ceftazidime in Epithelial Lining Fluid and Plasma

Healthy

United Kingdom
Uppsala University Hospital
Swedish Heart Lung Foundation

Unknown

Catheter Ablation Compared With Pharmacological Therapy for Atrial Fibrillation (CAPTAF Trial) (CAPTAF)

Quality of Life | Atrial Fibrillation

Sweden
H. Lundbeck A/S

Terminated

Efficacy and Safety Study of Desmoteplase to Treat Acute Ischemic Stroke (DIAS-4)

Stroke

Chile, United States, Belgium, Brazil, Canada, Denmark, Finland, Ireland, Italy, Mexico, Norway, South Africa, Sweden, United Kingdom
University of Messina

Completed

OHRQoL Evaluation After Functional Therapy in JIA Patients

Juvenile Idiopathic Arthritis

Italy
Rigshospitalet, Denmark

Unknown

uPAR PET/CT for Staging Advanced and Localised Oral and Oropharyngeal Cancer

Neoplasms | Neoplasms by Site | Head and Neck Neoplasms | Oral Cancer | Oropharyngeal Cancer | Cancer of Mouth

Denmark
Samsung Medical Center

Unknown

Angiographic Characteristics of CSC, PCV Patients and Thrombotic Bio-markers

Polypoidal Choroidal Vasculopathy | Central Serous Chorioretinopathy

Korea, Republic of
Kristoffer Staal Rohrberg
Janssen-Cilag Ltd.

Terminated

Urokinase Plasminogen Activator Receptor in Abiraterone Treated Patients With Castration Resistant Prostate Cancer (uPARCRPC)

Prostatic Neoplasms

Denmark
H. Lundbeck A/S

Completed

Efficacy and Safety Study of Desmoteplase to Treat Acute Ischemic Stroke (DIAS-3)

Stroke

Spain, Australia, Austria, Estonia, France, Germany, Hong Kong, India, Korea, Republic of, Netherlands, Philippines, Poland, Singapore, Switzerland, Taiwan, Thailand, Vietnam
Alaunos Therapeutics

Completed

Adenoviral Vector Monotherapy or Combination With Chemotherapy in Subjects With Recurrent/Metastatic Breast Cancer.

Breast Cancer Nos Metastatic Recurrent

United States
Alaunos Therapeutics

Completed

Safety Study of Adenovirus Vector Engineered to Express hIL-12 in Combination With Activator Ligand to Treat Melanoma

Melanoma

United States
ThromboGenics

Completed

Trial of Microplasmin Intravitreal Injection for Non-surgical Treatment of Focal Vitreomacular Adhesion. The MIVI-TRUST (TG-MV-006) Trial.

Vitreomacular Adhesion

United States
ThromboGenics

Completed

Trial of Microplasmin Intravitreal Injection for Non-Surgical Treatment of Focal Vitreomacular Adhesion. The MIVI-TRUST (TG-MV-007) Trial.

Vitreomacular Adhesion

United States, Spain, United Kingdom, Germany, Belgium, Czech Republic, Poland
University of Campinas, Brazil

Unknown

The Influence of Glycaemia and Insulinemia on Vasomotor Endothelial Function After Myocardial Infarction (INGLIVEF)

Myocardial Infarction

Brazil
ThromboGenics

Completed

Safety and Efficacy Study of Microplasmin in for Non-Surgical Treatment of Focal Vitreomacular Adhesion (MIVI-8)

Focal Vitreomacular Adhesion

Belgium
Queen's University

Completed

Urokinase Plasminogen Activator System in Benign Prostatic Hyperplasia

BPH

Canada
Marmara University

Completed

The Efficacy of Prophylactic Antibiotic Administration During Breast Cancer Surgery in Overweight Patients.

Breast Cancer

Turkey
University of Oklahoma

Completed

Urokinase Like Plasminogen Activator Levels in Patients Undergoing Bronchoscopy

Hemoptysis

United States
Forest Laboratories

Completed

Study of Desmoteplase (International Nonproprietary Name [INN]) in Acute Ischemic Stroke (DIAS-2)

Stroke, Acute

United States, Austria, Australia, Canada, Finland, Germany, Netherlands, Spain
Hallym University Medical Center

Unknown

4G/5G Polymorphism of Plasminogen Activator Inhibitor-1 Gene and Disseminated Intravascular Coagulation in Severe Sepsis and Septic Shock

Severe Sepsis
University of California, Los Angeles
ThromboGenics

Unknown

Study of Intravitreal Microplasmin in Relieving Vitreo-Macular Adhesion in Neovascular Age-related Macular Degeneration (AMD)

Macular Degeneration

United States
Ankara University

Unknown

Soluble Urokinase Plasminogen Activator Receptor (suPAR) in Late-onset Neonatal Sepsis (suPAR)

Neonatal Sepsis

Turkey
ARCA Biopharma, Inc.

Terminated

Phase 2 Proof-of-Concept Study of the Safety and Efficacy of Alfimeprase to Rapidly Open Arteries and Restore Brain Function Following a Stroke

Acute Ischemic Stroke

United States, Canada
PAION Deutschland GmbH

Completed

Dose Escalation of Desmoteplase in Acute Ischemic Stroke (DEDAS) (DEDAS)

Stroke
PAION Deutschland GmbH

Completed

Desmoteplase in Acute Ischemic Stroke (DIAS)

Stroke

Germany
Heidelberg Pharma AG
United States Department of Defense

Completed

Urokinase-Plasminogen Activator (uPA) Inhibitor WX-UK1 in Combination With Capecitabine in Advanced Malignancies

Advanced Malignancies

United States
ARCA Biopharma, Inc.

Terminated

Study of Alfimeprase's Ability to Dissolve Blood Clots in the Leg and Help Prevent the Need for Surgery

Arterial Occlusive Diseases

United States
ARCA Biopharma, Inc.

Completed

Study of Alfimeprase to Rapidly Dissolve Blood Clots in the Leg and Help Prevent the Need for Surgery on Leg Arteries

Arterial Occlusive Diseases

United States
Global Biotech

Completed

Safety Study of a Recombinant Human Plasminogen Activator to Treat Acute Ischemic Stroke.

Cerebrovascular Accident

Taiwan
King's College London

Not yet recruiting

Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases (PDO)

Breast Neoplasms
University of South Alabama

Not yet recruiting

Low Voltage Electrical Stimulation for Depression in Parkinson's Patients (LVESDIPP)

Parkinson Disease | Depressive Symptoms
AbbVie

Not yet recruiting

A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa
Concerto Biosciences

Not yet recruiting

Topical ENS-002 for Atopic Dermatitis in Adults (EnSync)

Atopic Dermatitis | Atopic Dermatitis Eczema

United States
Centre Hospitalier Universitaire de Saint Etienne
Sanofi Pasteur, a Sanofi Company

Not yet recruiting

Analyzes of Nasal Tissue-resident Memory Immune Cells and Peripheral Memory Cells Able to Migrate to Airway Tissues (MUCOVAC) (MUCOVAC)

Healthy Volunteers

France
Linkoeping University
Region Östergötland

Not yet recruiting

Combined Molecular and Mechanistic Methods for Detection of Pressure Ulcers

Inflammatory Response | Pressure Ulcer

Sweden
Institut du Cancer de Montpellier - Val d'Aurelle

Not yet recruiting

Efficacy of a Mixed Distancial Neuropsychological Rehabilitation Program in Patients With Grade 2 or 3 Diffuse Glioma (FREEDOME)

Glioma, Malignant
Septodont

Recruiting

Measurement of the Performance and Safety of RTR+Membrane in Guided Tissue Regeneration (GTR) in Dental Surgical Procedures (ObsR+)

Guided Bone Regeneration

France
Xin-Wu Cui
Hubei Cancer Hospital; First Affiliated Hospital of Kunming Medical University and other collaborators

Recruiting

Identification of Benign and Malignant Breast Nodules Using Ultrasound-modulated Optical Tomography: A Multicenter Study

Breast Cancer Female

China
Tampere University Hospital
University of Turku; Kuopio University Hospital; Tampere University; University... and other collaborators

Not yet recruiting

Study on Female Patients' Mammographic Texture Features (COMPRESS)

Breast Cancer | Artificial Intelligence | Mammography
Shanghai Simnova Biotechnology Co.,Ltd.

Not yet recruiting

F01 in the Treatment of Moderate-to-severe Refractory Systemic Lupus Erythematosus

Lupus Erythematosis

China
University of Alcala

Recruiting

Radiofrequency and Myofascial Pain Syndrome in Postpartum Pelvic Pain (RASDOP)

To be Approved by the Ethics Committee

Spain
University of Minnesota

Recruiting

Identification of Prodromal Neurodegeneration in Serotonergic-Induced REM Sleep Behavior Disorder

Parkinson Disease | REM Sleep Behavior Disorder | Dementia With Lewy Bodies

United States
Guangdong Hengrui Pharmaceutical Co., Ltd

Not yet recruiting

Efficacy and Safety Study of SHR-1819 Injection in Adult Patients With Severe Atopic Dermatitis

Moderate to Severe Atopic Dermatitis

China
Duke University

Not yet recruiting

A Phase 1 Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of JCXH-211 (SElf-Replicating RNA IL-12) Intratumoral Injection in Patients With Recurrent or Progressive High-Grade Glioma (SERIL)

Recurrent or Progressive High-grade Glioma
Second Affiliated Hospital, School of Medicine,...
Huashan Hospital; The Affiliated Nanjing Drum Tower Hospital of Nanjing University... and other collaborators

Not yet recruiting

Tract-based Artificial Intelligence (AI) Robot Guiding System in Basal Ganglion Hemorrhage Evacuation

Basal Ganglia Hemorrhage

China
Shanghai Bovax Biotechnology Co., Ltd.

Not yet recruiting

A Phase III Study to Evaluate the Efficacy, Immunogenicity and Safety of the 9-valent HPV Vaccine in Chinese Males

Anal Cancer | HPV-Related Carcinoma | Penile Cancer | Genital Wart | AIN3 | AIN2 | PIN-1 | AIN1 | PIN2 | PIN3

China
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Efficacy and Safety of Dupilumab in Combination With Tofacitinib in Moderate to Severe Adult AD Patients

Atopic Dermatitis
University of Nottingham
Wellcome Trust

Not yet recruiting

Measuring and Mapping Cognitive Decline After Brain Radiosurgery (CoDeB-Rad)

Quality of Life | Cognitive Decline | Brain Metastases | SRS | Meningiomas | Stereotactic Radiosurgery

United Kingdom

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