Search clinical trials for: topical JAK inhibitor

Total 87609 results

Beijing Tiantan Hospital

Recruiting

The Efficacy of WVI in Patients With Localized Basal Ganglia Intracranial Germ Cell Tumors

Intracranial Germ Cell CNS Tumor, Childhood

China
Atsushi Kawakami
AbbVie GK.

Recruiting

Discontinuation of Methotrexate in Rheumatoid Arthritis Patients Achieving Clinical Remission by Treatment With Upadacitinib Plus Methotrexate (DOPPLER)

Rheumatoid Arthritis | Biomarker | JAK Inhibitor | Musculoskeletal Ultrasound

Japan
University of Sao Paulo
Daiichi Sankyo, Inc.

Recruiting

Effects of Edoxaban on Platelet Aggregation (Edoxaban)

SCAD | AMI

Brazil
The Aurum Institute NPC
Johns Hopkins University

Recruiting

Comparing Treatment Completion Of Daily Rifapentine & Isoniazid For One Month (1HP) To Weekly High Dose Rifapentine & Isoniazid For 3 Months (3HP) In Persons Living With HIV and in Household Contacts of Recently Diagnosed Tuberculosis Patients (1 to 3)

Tuberculosis | HIV Seropositivity | Household Contact

South Africa, India, Indonesia, Mozambique
Brian Jerkins, MD
Ocular Therapeutix, Inc.

Not yet recruiting

DEXTENZA for the Treatment of Pain and Inflammation Following Surgical Trabeculectomy and Ahmed Valve Procedures (DEXTenSiVe)

Glaucoma Following Surgery

United States
Atsushi Kawakami
Gilead Sciences

Recruiting

Efficacy and Safety of Selective JAK 1 Inhibitor Filgotinib in Active Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate (TRANSFORM)

Rheumatoid Arthritis | Biomarker | JAK Inhibitor | Musculoskeletal Ultrasound | IL-6 Inhibitor

Japan
Stanford University
Orca Biosystems, Inc.

Recruiting

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Myelodysplastic Syndromes | Myeloproliferative Disorders | Acute Leukemia | Chronic Myelogenous Leukemia | Allogeneic Hematopoietic Cell Transplantation (HCT) | Advanced Hematologic Malignancies

United States
University of Southern California

Not yet recruiting

RCT: Trazodone vs Quetiapine vs Placebo for Treating ICU Delirium (TraQ) (TraQ)

Quality of Life | Delirium | Treatment Side Effects | Morality | Psych

United States
Ankara Training and Research Hospital

Recruiting

Comparison of the Efficacy and Safety of Continuous and Single-Dose Intravesical Epirubicin Instillation

Bladder Cancer | Superficial Bladder Cancer | Tumor Recurrence | Epirubicin Adverse Reaction

Turkey
Icahn School of Medicine at Mount Sinai

Recruiting

JAK Inhibition in Food Allergy

Food Allergy

United States
Fundación Pública Andaluza para la gestión de la...

Recruiting

Persistence of Biological Treatment and Inhibitors of Jak Kinases in Patients With Rheumatoid Arthritis. (Arthritis)

Arthritis, Rheumatoid

Spain
Mount Sinai Hospital, Canada

Recruiting

Low Molecular Weight hEparin vs. Aspirin Post-partum (LEAP)

Venous Thromboembolism

Canada
Chinese University of Hong Kong
National University Hospital, Singapore; The Affiliated Nanjing Drum Tower... and other collaborators

Recruiting

Labor Induction in Preeclampsia High-risk Women (FORECAST-IOL)

Pre-Eclampsia | Induction of Labor

Hong Kong, Thailand, Indonesia, Taiwan, Vietnam, Singapore, China
Britannia Pharmaceuticals Ltd.

Recruiting

Long-Term Observational Study on Effectiveness and Safety of Lecigon in Patients With Advanced Parkinson's Disease (ELEGANCE)

Advanced Parkinson Disease

Germany, Spain, Austria, Croatia, Romania, Slovenia, Belgium, Bulgaria, Czechia, Hungary, Ireland, Netherlands, Sweden
M.D. Anderson Cancer Center

Recruiting

Pembrolizumab and Lenvatinib for the Treatment of Advanced, Unresectable, or Metastatic Gastroesophageal Adenocarcinoma

Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction... and other conditions

United States
Emory University
National Cancer Institute (NCI)

Recruiting

Brentuximab Vedotin and Nivolumab for the Treatment of Relapsed/Refractory Classic Hodgkin Lymphoma Previously Treated With Brentuximab Vedotin or Checkpoint Inhibitors

Recurrent Classic Hodgkin Lymphoma | Refractory Classic Hodgkin Lymphoma

United States
Nerviano Medical Sciences

Recruiting

Ph I Study in Adult Patients With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

United States, Italy
PT. Prodia Stem Cell Indonesia

Recruiting

Combination of Conditioned Medium and Umbilical Cord-Mesenchymal Stem Cells Therapy for Acute Stroke Infarct

Ischemic Stroke

Indonesia
Seoul National University Hospital

Not yet recruiting

Effect of Dexmedetomidine on Quality of Recovery in Non-functioning Pituitary Adenoma Patients Undergoing Endoscopic Transsphenoidal Surgery

Non-functioning Pituitary Adenoma

Korea, Republic of
Chang Gung Memorial Hospital
Chang Gung University

Recruiting

Trial of PCSK9 Inhibition in Patients With Acute Stroke and Symptomatic Intracranial Atherosclerosis (TOPICAL-MRI)

Acute Ischemic Stroke | Intracranial Atherosclerosis | ICAS - Intracranial Atherosclerosis

Taiwan
M.D. Anderson Cancer Center

Recruiting

Immune Related Toxicity and Symptom Burden in Chronic Cancer Survivors With Melanoma Receiving Adjuvant Immunotherapy With Immune Checkpoint Inhibitors

Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Pathologic Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIA Cutaneous Melanoma... and other conditions

United States
Manchester University NHS Foundation Trust

Recruiting

PAIR (Paracetamol and Ibuprofen Research) Pilot Trial (PAIR)

Patent Ductus Arteriosus

United Kingdom
Dr Cipto Mangunkusumo General Hospital

Recruiting

The Role of Hypertonic Dextrose Spray as Endoscopic Topical Hemostatic Agent for Acute Non-Variceal Upper GI Bleeding

Gastro Intestinal Bleeding

Indonesia
Assiut University

Not yet recruiting

Topical Methotrexate Microemulsion in the Treatment of Plaque Psoriasis

Psoriasis | Methotrexate
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

The Efficacy and Safety of JAK Inhibitor in the Treatment of Anti-MDA5 Antibody-positive Dermatomyositis Patients

Dermatomyositis, Adult Type

China
Averitas Pharma, Inc.

Recruiting

Comparison of Qutenza (8% Capsaicin) With a Low-dose Capsaicin for Treatment of Nerve Pain After Surgery

Post Surgical Neuropathic Pain

United States, Spain, France, Netherlands, Poland, United Kingdom
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Recruiting

Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

Congenital Amegakaryocytic Thrombocytopenia | Paroxysmal Nocturnal Hemoglobinuria | Diamond-Blackfan Anemia | Shwachman-Diamond Syndrome | Bone Marrow Failure Syndrome | Hereditary Sideroblastic Anemia | Hematologic Neoplasm With Germline GATA2 Mutation | Hematologic Neoplasm With Germline SAMD9... and other conditions

United States
The University of Texas Health Science Center,...

Recruiting

Combination Intraventricular Chemotherapy Pilot Study: 5-Azacytidine (5-AZA) and Trastuzumab Infusions Into the Fourth Ventricle or Resection Cavity in Children and Adults With Recurrent or Residual Posterior Fossa Ependymoma

Fossa Ependymoma

United States
Louisiana State University Health Sciences Center...
Innovate Anti-Infectives

Recruiting

Outpatient Liquid Aspirin (OLA) (OLA COVID)

Covid19

United States
Wuhan University

Not yet recruiting

Exploratory Study of Neoadjuvant Treatment of HER2-positive Breast Cancer With Py in Combination With HP

Breast Cancer
Hams Hamed Abdelrahman

Recruiting

P11-4 and Nanosilver Fluoride Varnish in Treatment of White Spot Carious Lesions

White Spot Lesion

Egypt
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Radiation Therapy to Immunotherapy for Stage IV Non-Small Cell Lung Cancer Patients Who Are PD-L1 Negative

Lung Adenocarcinoma | Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | Lung Adenosquamous Carcinoma

United States
M.D. Anderson Cancer Center

Recruiting

Predictive Biomarkers for Pneumonitis After Chemoradiotherapy and Immunotherapy in Patients With Non-small Cell Lung Cancer

Lung Non-Small Cell Carcinoma

United States
Thomas Benfield

Recruiting

Changes in Weight, Body Composition and Metabolic Parameters After Discontinuing Dolutegravir or Tenofovir Disproxil (AVERTAS-2)

HIV Infections | Obesity | Renal Insufficiency | Osteoporosis | Hiv | Weight Gain | HIV Lipodystrophy

Denmark
Oregon Health and Science University

Recruiting

Baricitinib in the Treatment of Adults With Pyoderma Gangrenosum (PG)

Skin Diseases | Skin Ulcer | Wound Heal | Pyoderma | Pyoderma Gangrenosum

United States
Penza State University

Recruiting

Evaluation of the Effect of Long-term Lipid-lowering Therapy in STEMI Patients With Coronavirus Infection COVID-19 (CONTRAST-3)

Covid19 | STEMI | NSTEMI

Russian Federation
M.D. Anderson Cancer Center

Recruiting

Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 Therapy

Stage III Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIA Lung Non-Small Cell Cancer AJCC v7 | Stage IIIC Lung Cancer AJCC v8 | Stage IIIB Lung Non-Small Cell Cancer AJCC v7 | Stage III Lung Non-Small Cell Cancer AJCC v7

United States
Emory University
National Cancer Institute (NCI); AstraZeneca

Recruiting

Acalabrutinib and Obinutuzumab for the Treatment of Previously Untreated Follicular Lymphoma or Other Indolent Non-Hodgkin Lymphomas

Mantle Cell Lymphoma | Marginal Zone Lymphoma | Lymphoplasmacytic Lymphoma | Lymphoproliferative Disorder | Indolent Non-Hodgkin Lymphoma | Grade 1 Follicular Lymphoma | Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma

United States
Erasmus Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

NMF-CsA-Dupi Trial

Dermatitis, Atopic

Netherlands
Novartis Pharmaceuticals

Recruiting

Asciminib Roll-over Study

Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Chronic Myelogenous Leukemia

Denmark, Spain, France, Germany, Lebanon, Italy, Argentina, Czechia, Portugal, United Kingdom, Brazil, Mexico, Taiwan, Austria, Canada, Korea, Republic of, Russian Federation, Turkey, United States, Singapore, Japan, Bulgaria, Poland, Romani... and more
University of Michigan
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Recruiting

The Back Pain Consortium Research Program Study (BACPAC)

Chronic Low-back Pain

United States
Ohio State University Comprehensive Cancer Center

Recruiting

Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
Genentech, Inc.

Recruiting

A Study Assessing Corneal Endothelial Cells in Patients With Neovascular Age-related Macular Degeneration Treated With the Port Delivery System With Ranibizumab (PDS) (Belvedere)

Neovascular Age-related Macular Degeneration

United States
Tongji Hospital

Recruiting

Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis

Ischemic Stroke | Large-Artery Atherosclerosis (Embolus/Thrombosis)

China
Vanderbilt University Medical Center
Veloxis Pharmaceuticals

Recruiting

Cognitive Outcomes in Stable Renal Transplant Patients Switched fromTacrolimus to Envarsus XR™ (OPERATOR)

Renal Transplant

United States
Pharmtechnology LLC
ClinPharmInvest, LLC

Not yet recruiting

Bioequivalence Study of Two Formulations of Etoricoxib Tablets 120 mg in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
Mingzhi Zhang

Recruiting

A Prospective Clinical Study of BTK Inhibitor, PD-1 and Formustine in the First-line Treatment of Primary Central Nervous System Lymphoma

Primary Central Nervous System Lymphoma

China
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Futibatinib and Pembrolizumab for Treatment of Advanced or Metastatic FGF19 Positive BCLC Stage A, B, or C Liver Cancer

Advanced Hepatocellular Carcinoma | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma | Metastatic Hepatocellular Carcinoma | BCLC Stage A Hepatocellular Carcinoma

United States
Chang Gung Memorial Hospital

Recruiting

Statin and Dual Antiplatelet Therapy to Prevent Early Neurological Deterioration in Branch Atheromatous Disease (SATBRAD)

Dual Antiplatelet Therapy | Acute Stroke | Statin

Taiwan
University of Michigan
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Vigor and the LDR in Parkinson Disease

Parkinson Disease

United States

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