Search clinical trials for: Rare Diseases

Total 377150 results

National Center for Research Resources (NCRR)
National Multiple Sclerosis Society

Completed

Antibiotic Treatment Trial Directed Against Chlamydia Pneumonia in Multiple Sclerosis

Multiple Sclerosis

United States
Immunobiology Research Institute

Completed

Double-Blind Study of Timunox (Thymopentin) in Asymptomatic HIV-Infected Patients Receiving Either Mono (AZT or ddI) or Combination (AZT / ddI or AZT / ddC) Anti-Retroviral Therapy

HIV Infections

United States, Puerto Rico
G D Searle

Completed

Initial Phase II Efficacy and Safety Study of SC-48334 Administered in Combination With Low-Dose Zidovudine (AZT) to Symptomatic HIV-1 Infected Patients With = or > 200 to = or < 500 CD4+ Cells/mm3

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

Indinavir Plus Efavirenz Plus Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Had Success With Nelfinavir

HIV Infections

United States
Merck Sharp & Dohme LLC

Terminated

Safety and Effectiveness of Giving L-743,872 to Patients With Thrush That Has Not Been Cured With Fluconazole

HIV Infections | Candidiasis, Oral

United States
Sarawak MediChem Pharmaceuticals

Unknown

The Safety and Effectiveness of (+)-Calanolide A in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Otsuka America Pharmaceutical

Completed

A Long-Term, Follow-On Safety Study of Four Doses of OPC-8212 (Vesnarinone) in HIV-Infected Persons

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of Zidovudine and T Lymphocyte Transfer in the Treatment of HIV Type III in Patients With AIDS

HIV Infections

United States
Glaxo Wellcome

Completed

Trial of an Alternative Dosing Regimen of Oral Retrovir in Patients With AIDS or Advanced ARC

HIV Infections

United States, Puerto Rico
Gilead Sciences

Completed

The Safety and Effectiveness of Adefovir Dipivoxil Plus Indinavir Combined With Zidovudine or Lamivudine or Stavudine in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
G D Searle

Completed

Phase II Study of the Safety and Surrogate Marker Efficacy of Butyldeoxynojirimycin (SC-48334) and AZT in Symptomatic HIV-1 Infected Patients With 200 - 500 CD4+ Cells/mm3. (NOTE: Asymptomatic HIV-1 Infected Patients Also Eligible)

HIV Infections

United States
Immunobiology Research Institute

Completed

Double Blind Study of Thymopentin Effects on HIV-1 Infectivity of Blood Mononuclear Cells and Semen in HIV Infected Patients

HIV Infections

United States
Gathe, Joseph, M.D.

Unknown

Ritonavir and Agenerase Treatment for Patients Who Have Failed Previous Anti-HIV Treatment

HIV Infections

United States
Shaman Pharmaceuticals

Completed

A Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Orally Administered SP-303 for the Treatment of Diarrhea in Acquired Immunodeficiency Syndrome (AIDS) Patients

HIV Infections | Diarrhea

United States, Puerto Rico
Otsuka Pharmaceutical Development & Commercialization...

Completed

Study to Compare the Effects of Two Dosages of Tolvaptan in Congestive Heart Failure Patients

Congestive Heart Failure

United States
Milkhaus Laboratory

Unknown

A 20-Week Study of a New Treatment for Men With Benign Prostatic Hyperplasia (BPH).

Prostatic Hyperplasia

United States
National Center for Research Resources (NCRR)

Completed

A Clinical Trial to Prevent the Complications of Insulin Resistance (Including Type-2 Diabetes)

Diabetes Mellitus | Insulin Resistance

United States
University of Southern California

Completed

Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients

HIV Infections | Salmonella Infections

United States
Glaxo Wellcome

Completed

Safety and Effectiveness of Lamivudine When Given Once a Day Versus Twice a Day in Combination With Other Anti-HIV Drugs in HIV-Infected Adults Who Have Never Received Anti-HIV Drugs

HIV Infections

United States, Canada, Argentina, Brazil, Puerto Rico
Oxo Chemie GmbH

Completed

A Study of WF 10 IV Solution in Patients With Advanced HIV Disease

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

A Study on the Safety and Effectiveness of L-756423 Plus Indinavir in HIV-Positive Patients Who Have Previously Taken Indinavir

HIV Infections

United States
Genentech, Inc.

Completed

A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Patients With AIDS and AIDS-Related Complex

HIV Infections

United States
Hoffmann-La Roche

Completed

A Randomized, Open-Label Study of Alternative Treatment Combinations of Dideoxycytidine (HIVID; ddC) and Zidovudine (AZT) in Patients With HIV Infection

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of Amprenavir in Patients With Protease Inhibitor-Related Complications

HIV Infections

United States
Glaxo Wellcome

Unknown

Effectiveness and Safety of Epivir/Ziagen/Zerit (3TC/ABC/d4T) Versus Epivir/Ziagen/Sustiva (3TC/ABC/EFV) Versus Epivir/Ziagen/Agenerase/Norvir (3TC/ABC/APV/RTV) in HIV Patients Who Have Never Received Treatment

HIV Infections

United States
National Center for Research Resources (NCRR)

Unknown

Effect of Pravastatin on Endothelial Dysfunction Following a Single High Fat Meal

Heart Diseases

United States
Harborview Injury Prevention and Research Center

Unknown

Prevention of Shaken Baby Syndrome

Child Abuse | Shaken Baby Syndrome

United States
Eunice Kennedy Shriver National Institute of Child...
National Institute of Mental Health (NIMH)

Completed

Improving Mental Health Services for Economically Disadvantaged Children: Training Teachers

Psychopathology

United States
Glaxo Wellcome

Completed

An Open-Label Study to Evaluate the Efficacy and Safety of Amprenavir (141W94) and Abacavir Combination Therapy in Protease Inhibitor Experienced Subjects With HIV-1 Infection Who Are Failing Their Current Antiretroviral Treatment Regimen

HIV Infections

United States
Chiron Corporation

Unknown

Safety and Effectiveness of L2-7001 (Interleukin-2) in HIV-Positive Patients Receiving Anti-HIV Therapy

HIV Infections

United States
Pfizer

Completed

A Comparison of Fluconazole and Ketoconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems

HIV Infections | Candidiasis, Esophageal

United States, Canada
National Center for Research Resources (NCRR)
Elizabeth Glaser Pediatric AIDS Foundation

Completed

The Metabolic Effects of Protease Inhibitors in HIV Infected Children

HIV Infections

United States
National Center for Research Resources (NCRR)
Murray Fellowship

Completed

Pediatric Traumatic Brain Injury: Methylphenidate Effects on Early Recovery

Brain Injuries

United States
National Eye Institute (NEI)

Unknown

Early Manifest Glaucoma Trial (EMGT)

Open-Angle Glaucoma

Sweden
National Center for Research Resources (NCRR)

Completed

Double-Blind, Placebo-Controlled Trial of Vitamin E as Add-on Therapy for Children With Epilepsy

Epilepsy

United States
Parexel

Completed

The Safety and Effectiveness of Retrovir Plus HIVID Combined With Either Nevirapine or Invirase in the Treatment of HIV Infection

HIV Infections

United States
National Center for Research Resources (NCRR)

Unknown

The Effect of Estrogen and Progesterone Levels on Knee and Ankle Joint Laxity

Healthy

United States
Chiron Corporation

Completed

A Phase I Study of Subcutaneously Administered Proleukin (Aldesleukin) in HIV-Infected Patients

HIV Infections

United States
National Center for Research Resources (NCRR)

Completed

Continuously Infused Intracerebral (IC) Recombinant-Methionyl Human Glial Cell Line-Derived Neurotrophic Factor (r-metHuGDNF) for the Treatment of Idiopathic Parkinson's Disease

Parkinson Disease

United States
ICOS Corporation

Completed

Interstitial Cystitis

Interstitial Cystitis

United States
Pharmacia

Completed

A Study of Thymic Humoral Factor (THF Gamma 2) in HIV-Infected Patients

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.

Completed

A Phase I Study of the Safety and Pharmacokinetics of Recombinant Human CD4 Immunoglobulin (rCd4-IgG) Administered by Intravenous Bolus in Patients With AIDS and AIDS Related Complex

HIV Infections

United States
Argus Pharmaceuticals

Completed

Pharmacokinetics of Nystatin LF I.V. in Patients With Acquired Immune Deficiency Syndrome-Related Complex (ARC)

HIV Infections

United States
National Eye Institute (NEI)

Completed

Krypton-Argon Regression of Neovascularization Study (KARNS)

Diabetes Mellitus | Diabetic Retinopathy | Retinal Neovascularization
Glaxo Wellcome

Completed

A Phase I Study to Evaluate the Pharmacokinetics, Safety and Antiviral Effects of Concurrent Administration of Zidovudine (AZT) and 2'3'-Dideoxyinosine (ddI) in Patients With Human Immunodeficiency Virus (HIV)

HIV Infections

United States
Advanced Peptides

Completed

Intranasal Peptide T in the Treatment of Painful Peripheral Neuropathy of AIDS

HIV Infections | Peripheral Nervous System Disease

United States
Free Radical Sciences

Completed

A Double-Blind, Randomized Parallel Group Study Comparing Procysteine to Placebo in HIV-Infected Patients Who Are Taking Antiretroviral Nucleosides

HIV Infections
Dupont Merck

Completed

A Study of Efavirenz in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
GlaxoSmithKline

Unknown

Comparison of Two Dosing Regimens of GW433908/Ritonavir Versus Lopinavir/Ritonavir for 48 Weeks in HIV Patients Who Have Taken Protease Inhibitors and Experienced Virological Failure

HIV Infections

United States
R W Johnson Pharmaceutical Research Institute

Completed

Treatment Program for Anemia in AIDS Patients

HIV Infections | Cytopenias

United States

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